Neil Foster

Contact

• workRoom C21 Veterinary Academic Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 951 6433
• fax0115 951 6440
• n.foster@nottingham.ac.uk

Research Summary

My research interests are concerned with the initial interaction of myeloid immune cells with bacterial pathogens and the development of inflammation. Specifically, my interests include the biology… read more

Selected Publications

• FOSTER, N., CHEETHAM, J., TAYLOR, J.J. and PRESHAW, P.M., 2005. VIP inhibits Porphyromonas gingivalis LPS-induced immune responses in human monocytes Journal of Dental Research. 84(11), 999-1004

• View all publications

Current Research

My research interests are concerned with the initial interaction of myeloid immune cells with bacterial pathogens and the development of inflammation. Specifically, my interests include the biology of novel IL-1 cytokines and the therapeutic potential of vasoactive intestinal peptide (VIP) in humans and also in porcine and murine models. I also have research interests in the development of innate cells vaccines for control of bacterial disease

Past Research

The role of VIP as a TLR inhibitor

Survival of opportunistic pathogens following VIP administration

Future Research

I would welcome enquiries from colleagues regarding any field in which I currently have interests.

• FOSTER N and ELSHEIKHA HM, 2012. The Immune Response To Parasitic Helminths Of Veterinary Importance And Its Potential Manipulation For Future Vaccine Control Strategies. Parasitology Research: 110(5):1587-99. 110(5), 1587-1599
• FOSTER, N., TURNBULL, E.L. and MACPHERSON, G., 2012. Migrating lymph dendritic cells contain intracellular CD40 that is mobilized to the immunological synapse during interactions with Antigen-specific T lymphocytes Journal of Immunology. 189(12), 5632-5637
• FOSTER, N., BERNDT A,, LALMANACH AC, METHNER U, PASQUALI P, RYCHLIK I, VELGE P, ZHOU X and BARROW P, 2011. Emergency and therapeutic vaccination - Is stimulating innate immunity an option? Res Vet Sci. (In Press.)
• FOSTER N., 2011. Analysis of short answer question styles versus gender in preclinical veterinary education. J. Vet. Med Edu. 38, 67-73
• MUTAMBA, S., ALLISON, A., MAHIDA, Y., BARROW, P. and FOSTER, N., 2011. Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9 European Journal of Immunology. 42(3), 607-17
• ROSHIER AL, FOSTER N and JONES MA, 2011. Veterinary Students' Usage And Perception Of Video Teaching Resources. Bmc Medical Education. 11, 1
• FOSTER, N. and ELSHEIKHA HM, 2010. The immune defence of the host. In: ELSHEIKHA, HM and KHAN, NA, eds., Essentials of Clinical Veterinary Parasitology Caister Academic Press. 27-33
• RAUCH C, PLUEN A, FOSTER N, LOUGHNA P, MOBASHERI A, LAGADIC-GOSSMANN D and COUNILLON L, 2010. On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives Cell Biochem Biophys. 56, 73-90
• FOSTER, N. and MACPHERSON, G.G., 2010. Murine cecal patch M cells transport scrapie-associated fibrils in vivo Journal of Infectious Diseases. 202(12), 1916-1919
• IBRAHIM, I., BARROW, P. and FOSTER, N., 2010. Transcriptional regulation by VIP and its therapeutic potential Clinical Epigenetics. 2, 213-222
• FOSTER, N., GARDNER, D., KYDD, J., ROBINSON, R. and ROSHIER, M., 2010. Assessing the influence of gender, learning style and pre-entry experience on student response to delivery of a novel veterinary curriculum Journal of Veterinary Medical Education. 37(3), 266-275
• SMALLEY, S.G.R., BARROW, P.A. and FOSTER, N., 2009. Immunomodulation of innate immune responses by vasoactive intestinal peptide (VIP): its therapeutic potential in inflammatory disease Clinical & Experimental Immunology. 157(2), 225-234
• PRESHAW, P.P and FOSTER, N. AND TAYLOR, J.J, 2007. Cross-susepibilty between periodontal disease and type 2 diabetes mellitus:an immunological persective. Periodontology 2000. 45, 138-157
• FOSTER N, ANDREADOU K, JAMIESON L, PRESHAW P.M, TAYLOR J.J., 2007. Vasoactive Intestinal Peptide Inhibits P. gingivalis Lipopolysaccaride induced IL-18 and IL-18BPa in Monocytes J. Dent Res. 86, 883-887
• FOSTER N., LEA, S.R., PRESHAW, P.M. and TAYLOR, J.J., 2007. Pivotal Advance: vasoactive intestinal peptide inhibits up-regulation of human monocyte TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages Journal of Leukocyte Biology. 81(4), 893-903
• FOSTER, N., HULME, S. D. and BARROW, P. A., 2005. Inhibition of IFN-g-Stimulated Proinflammatory Cytokines by Vasoactive Intestinal Peptide (VIP)Correlates with Increased Survival of Salmonella enterica serovar typhimurium phoP in Murine Macrophages Journal of Interferon and Cytokine Research. VOL 25(NUMBER 1), 31-42
• FOSTER, N., HULME, S., LOVELL, M., REED, K. and BARROW, P., 2005. Stimulation of gp91 phagocytic oxidase and reactive oxygen species in neutrophils by an avirulent Salmonella enterica serovar Infantis strain protects gnotobiotic piglets from lethal challenge with serovar Typhimurium strain F98 without inducing intestinal pathology Infection and Immunity. 73(8), 4539-4547
• VAN IMMERSEEL, F., METHNER, U., RYCHLIK, I., NAGY, B., VELGE, P., MARTIN, G., FOSTER, N., DUCATTELLE, R. and BARROW, P. A., 2005. Vaccination and early protection against non-host-specific Salmonella serotypes in poultry: exploitation of innate immunity and microbial activity Epidemiology and Infection. VOL 133(NUMB 6), 959-978
• LEA, S.R., CUI, Y., TAYLOR, J.J., PRESHAW, P.M. and FOSTER, N., 2005. Novel IL-1 family cytokines stimulate IL-6 production in a human keratinocyte cell line. Immunology. 116, 56
• FOSTER, N., CHEETHAM, J., TAYLOR, J.J. and PRESHAW, P.M., 2005. VIP inhibits Porphyromonas gingivalis LPS-induced immune responses in human monocytes Journal of Dental Research. 84(11), 999-1004
• FOSTER, N. and HIRST, B.H., 2005. Exploiting receptor biology for oral vaccination with biodegradable particulates Advanced Drug Delivery Reviews. 57(3), 431-450
• FOSTER, N., CHEETHAM, J., PRESHAW, P.M. and TAYLOR, J.J., 2004. Dowregulation of inflammatory cytokines by vasoactive intestinal peptide; novel therapeutic for periodintal disease. Immunology. 113, 111
• FOSTER, N., HULME, S. D. and BARROW, P. A., 2003. Induction of Antimicrobial Pathways during Early-Phase Immune Response to Salmonella spp. in Murine Macrophages: Gamma Interferon (IFN-gamma) and Upregulation of IFN-gamma Receptor Alpha Expression Are Required for NADPH Phagocytic Oxidase gp91-Stimulated Oxidative Burst and Control of Virulent Salmonella spp Infection and Immunity. VOL 71(PART 8), 4733-4741
• TOTEMEYER, S., FOSTER, N., KAISER, P., MASKELL, D. J. and BRYANT, C. E., 2003. Toll-Like Receptor Expression in C3H/HeN and C3H/HeJ Mice during Salmonella enterica Serovar Typhimurium Infection Infection and Immunity. VOL 71(PART 11), 6653-6657
• FOSTER, N., LOVELL, M.A., MARSTON, K.L., HULME, S.D., FROST, A.J., BLAND, P. and BARROW, P.A., 2003. Rapid protection of gnotobiotic pigs against experimental salmonellosis following induction of polymorphonuclear leukocytes by avirulent Salmonella enterica Infection and Immunity. 71(4), 2182-2191
• JONES, M.A., FOSTER, N., PAGE, K., HULME, S.D. and BARROW, P.A., 2002. Salmonella enterica serovar Typhimurium F98 modulation of NO production is not host cell dependent and is inv/spa dependent. In: The International Symposium on Salmonella and Salmonellosis.. 203-204
• FOSTER, N., 1998. Immunocytochemical detection of vasoactive intestinal peptide-like and peptide histidine isoleucine-like peptides in the nervous system and the excretory system of adult Nippostrongylus brasiliensis Int J. Parasitol. 28, 825-829
• FOSTER, N., CLARK M.A., JEPSON M.A. and HIRST B.H., 1998. Ulex europaeus 1 lectin targets microspheres to mouse Peyer’s patch M cells in vivo Vaccine. 16, 536-541
• FOSTER N, GARDNER D, KYDD J, ROBINSON R and ROSHIER M, 1. Assessing The Influence Of Gender, Learning Style, And Pre-Entry Experience On Student Response To Delivery Of A Novel Veterinary Curriculum. Journal Of Veterinary Medical Education. 37(3), 266-75
• FOSTER N, 1. Analysis Of Short-Answer Question Styles Versus Gender In Pre-Clinical Veterinary Education. Journal Of Veterinary Medical Education. 38(1), 67-73