Natalie Mack

Contact

• workRoom C08 Bioenergy and Brewing Science building (BABS)
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work01159516623
• Natalie.Mack@nottingham.ac.uk

Biography

Current committee membership and other key roles:

• School of Biosciences UG Academic Misconduct Chair
• Admissions tutor for UG Biotechnology courses
• School of Biosciences Athena SWAN self-assessment team
• School of Biosciences EDI committee
• School of Biosciences Research Ethics Committee

Teaching Summary

I teach on a range of modules for both UG and PGT Biotechnology students, specialising in topics related to animal biotechnology.

I am module convenor for (and teach on) the following 4 modules: BIOS4116 Research Techniques in Biotechnology, BIOS4121 Industrial and Commercial aspects of Animal Biotechnology, BIOS4122 Animal Biotechnology, BIOS2082 Research skills for Biotechnologists.

In addition, I teach on the following 3 modules: BIOS1053 An Introduction to Biotechnology, BIOS4006 Basic Laboratory Techniques, BIOS4128 Cell Factories.

I also supervise Biotechnology student research projects on several topics including Cancer and Alzheimer's disease. I am also the subject coordinator for BSc and MSci Biotechnology student research projects.

Recent Publications

• URAS, GIUSEPPE, MANCA, ALESSIA, ZHANG, PENGFEI, MARKUS, ZSUZSA, MACK, NATALIE, ALLEN, STEPHANIE, BO, MARCO, XU, SHENGTAO, XU, JINYI, GEORGIOU, MARIOS and ZHU, ZHEYING, 2021. In vivo Evaluation of a Newly Synthesized Acetylcholinesterase Inhibitor in a Transgenic Drosophila Model of Alzheimer's Disease. Frontiers in neuroscience. 15, 691222
• COUTINO, BRENDA CANALES, CORNHILL, ZOE E., COUTO, AFRICA, MACK, NATALIE A., RUSU, ALEXANDRA D., NAGARAJAN, USHA, FAN, YUEN NGAN, HADJICHARALAMBOUS, MARINA R., URIBE, MARCOS CASTELLANOS, BURROWS, AMY, LOURDUSAMY, ANBARASU, RAHMAN, RUMAN, MAY, SEAN T. and GEORGIOU, MARIOS, 2020. A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion ISCIENCE. 23(6),
• PORTER AP, WHITE GRM, MACK NA, MALLIRI A, 2019. The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia J Cell Sci.
• COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385

• View all publications

• URAS, GIUSEPPE, MANCA, ALESSIA, ZHANG, PENGFEI, MARKUS, ZSUZSA, MACK, NATALIE, ALLEN, STEPHANIE, BO, MARCO, XU, SHENGTAO, XU, JINYI, GEORGIOU, MARIOS and ZHU, ZHEYING, 2021. In vivo Evaluation of a Newly Synthesized Acetylcholinesterase Inhibitor in a Transgenic Drosophila Model of Alzheimer's Disease. Frontiers in neuroscience. 15, 691222
• COUTINO, BRENDA CANALES, CORNHILL, ZOE E., COUTO, AFRICA, MACK, NATALIE A., RUSU, ALEXANDRA D., NAGARAJAN, USHA, FAN, YUEN NGAN, HADJICHARALAMBOUS, MARINA R., URIBE, MARCOS CASTELLANOS, BURROWS, AMY, LOURDUSAMY, ANBARASU, RAHMAN, RUMAN, MAY, SEAN T. and GEORGIOU, MARIOS, 2020. A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion ISCIENCE. 23(6),
• PORTER AP, WHITE GRM, MACK NA, MALLIRI A, 2019. The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia J Cell Sci.
• COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385
• MACK NA and GEORGIOU M, 2014. The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases. 5(2), 10
• VAUGHAN L, TAN CT, CHAPMAN A, NONAKA D, MACK NA, SMITH D, BOOTON R, HURLSTONE AF and MALLIRI A, 2014. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. Cell reports. 10(1), 88-102
• MACK NA, PORTER AP, WHALLEY HJ, SCHWARZ JP, JONES RC, KHAJA ASS, BJARTELL A, ANDERSON KI and MALLIRI A, 2012. β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nature cell biology. 14(11), 1169-80
• MACK NA, WHALLEY HJ, CASTILLO-LLUVA S and MALLIRI A, 2011. The diverse roles of Rac signaling in tumorigenesis. Cell cycle (Georgetown, Tex.). 10(10), 1571-81
• GRIFFITHS GJ, KOH MY, BRUNTON VG, CAWTHORNE C, REEVES NA, GREAVES M, TILBY MJ, PEARSON DG, OTTLEY CJ, WORKMAN P, FRAME MC and DIVE C, 2004. Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis. The Journal of biological chemistry. 279(44), 46113-21