Centre for Biomolecular Sciences

Archive of Publications

Publications 2013

A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity. Maryati M, Kaur I, Jadhav GP, Olotu-Umoren L, Oveh B, Hashmi L, Fischer PM, Winkler GS. 2013. Nucleic Acids Res. doi: 10.1093/nar/gkt972.

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice. Moreno JA, Halliday M, Molloy C, Radford H, Verity N, Axten JM, Ortori CA, Willis AE, Fischer PM, Barrett DA, Mallucci GR. October 2013. Science Translational Medicine Vol 5, Issue 206ra138.

Exon skipping and gene transfer restore dystrophin expression in hiPSC-cardiomyocytes harbouring DMD mutations. Dick E, Kalra S, Anderson D, George V, Ritso M, Laval SH, Barresi R, Aartsma-Rus A, Lochmüller H and Denning C. 2013. Stem Cells Dev. 2013 Jul 5. [Epub ahead of print]

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes. Matsa E, Dixon JE, Medway C, Georgiou O, Patel MJ, Morgan K, Kemp PJ, Staniforth A, Mellor I and Denning C. 2013. Eur Heart J. 2013 Mar 6. [Epub ahead of print].

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis. Rannou O, Le Chatelier E, Larson MA, Nouri H, Dalmais B, Laughton C, Jannière L and Soultanas P. 2013. Nucleic Acids Res 1;41(10):5303-20.

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis. Oldfield NJ, Matar S, Bidmos FA, Alamro M, Neal KR, Turner DPJ, Bayliss CD and Ala’Aldeen DAA. 2013. PLoS ONE 8, e69746.

Deciphering the contribution of human meningothelial cells to the inflammatory / antimicrobial response at the meninges. Royer P-J, Rogers, AJ, Wooldridge KG, Tighe PJ, Mahdavi J, Rittig MG and Ala'Aldeen, DAA. 2013. Infection and Immunity. (In Press.)

Helicobacter pylori downregulates expression of human β-defensin 1 in the gastric mucosa in a type IV secretion dependent fashion. Patel SR, Smith K, Letley DP, Cook KW, Memon AA, Ingram RJM, Staples E, Backert S, Zaitoun AM, Atherton JC and Robinson K. 2013. Cellular Microbiology DOI10.1111/ cmi.12174

D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors. Bay-Richter C, O'Callaghan MJ, Mathur N, O'Tuathaigh CM, Heery DM, Fone KC, Waddington JL, Moran PM. Neuropsychopharmacology. 2013 Jul;38(8):1512-20.

Keap Calm, and Carry on Covalently. Wilson AJ, Kerns JK, Callahan JF and Moody CJ. J Med Chem 2013, 56, 7463-7476.

Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells. Collins HM, Abdelghany MK, Messmer M, Yue B, Deeves SE, Kindle KB, Mantelingu K, Aslam A, Winkler GS, Kundu TK, Heery DM. BMC Cancer. 2013 Jan 29;13:37.

Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). Ilangovan A, Fletcher M, Rampioni G, Pustelny C, Rumbaugh K, Heeb S, Cámara M, Truman A, Chhabra R, Emsley J and Williams P. (2013) PLoS Pathogens 9(7):e100350).

Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN. Morris ER, Hall G, Li C, Heeb S, Kulkarni RV, Lovelock L, Silistre H, Messina M, Cámara M, Emsley J, Williams P and Searle MS. (2013) Structure. 2013 Sep 21:1659-71.

Interference with the germination and growth of Ulva zoospores by quorum sensing molecules from Ulva-associated epiphytic bacteria. Twigg, MS, Tait K, Williams P, Atkinson S and Cámara M. (2013) Environmental Microbiol. (In press).

A Signature Motif Mediating Selective Interactions of BCL11A with the NR2E/F Subfamily of Orphan Nuclear Receptors. Chan CM, Fulton J, Montiel-Duarte C, Collins HM, Bharti N, Wadelin F, Moran PM, Mongan NP and Heery DM. 2013. Nucleic Acids Research.

PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs. Wadelin FR, Fulton J, Collins HM, Tertipis N, Bottley A, Spriggs KA, Falcone FH and Heery DM. 2013. PLoS ONE 8(2).

Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions: synthesis of alpha-sulfanyl, alpha-sulfonyl, and alpha-phosphono carboxylates. Bartrum HE, Blakemore DC, Moody CJ and Hayes CJ. 2013. Tetrahedron, 69 (10), 2276-2282.

Catalytic Reduction of ortho- and para-Azidonitrobenzenes via tert-Butoxide Ion Mediated Electron Transfer. Burnley J, Carbone G and Moses JE. 2013. Synlett 2013, (5), 652-656.

Foresight Technical Conference Illuminating Feynman's Vision. Champness NR. 2013. Nature Nanotechnology, 8 (3), 163-164.

Small-Scale Structure of the Interstellar Medium Toward rho Oph Stars: Diffuse Band Observations. Cordiner MA, Fossey SJ, Smith AM and Sarre PJ. 2013. Astrophysical Journal Letters, 764 (1).

Chlorostannate(II) Ionic Liquids: Speciation, Lewis Acidity, and Oxidative Stability. Currie M, Estager J, Licence P, Men S, Nockemann P, Seddon KR, Swadzba-Kwasny M and Terrade C. 2013. Inorganic Chemistry, 52 (4), 1710-1721.

Calculating Excited State Properties using Kohn-Sham Density Functional Theory. Hanson-Heine MWD, George MW and Besley NA. 2013. Journal of Chemical Physics 138 (6).

Chitin Nanowhisker Aerogels. Heath L, Zhu LF and Thielemans W. 2013. Chemsuschem, 6 (3), 537-544.

Injection locking of violet laser diodes with a 3.2 GHz offset frequency for driving Raman transitions in Ca-43(+). Keitch BC, Thomas NR and Lucas DM. 2013. Optics Letters, 38 (6), 830-832.

Rheological studies of polycaprolactone in supercritical CO2. Kelly CA, Murphy SH, Leeke GA, Howdle SM, Shakesheff KM and Jenkins MJ. 2013. European Polymer Journal, 49 (2), 464-470.

Single-Molecule Magnetism in a Single-Ion Triamidoamine Uranium(V) Terminal Mono-Oxo Complex**Angew. King DM, Tuna F, McMaster J, Lewis W, Blake AJ, McInnes EJL and Liddle ST. 2013. Chem. Ind. 52, 4921–4924.

Cucurbituril: A promising organic building block for the design of coordination compounds and beyond. Lu J, Lin JX, Cao MN and Cao R. 2013. Coordination Chemistry Reviews, 257 (7-8), 1334-1356.

Reactivity Studies of a T-Shaped Yttrium Carbene: C-F and C-O Bond Activation and C=C Bond Formation Promoted by (Y(BIPM)(I)(THF)(2) (BIPM = C(PPh2NSiMe3)(2)). Mills DP, Lewis W, Blake AJ and Liddle ST. 2013. Organometallics, 32 (5), 1239-1250.

Reactivity of the Yttrium Alkyl Carbene Complex Y(BIPM)(CH2C6H5)(THF) (BIPM = (C(PPh2NSiMe3)(2)))(2-): From Insertions, Substitutions, and Additions to Nontypical Transformations. Mills DP, Soutar L, Cooper OJ, Lewis W, Blake AJ and Liddle ST. 2013. Organometallics, 32 (5), 1251-1264.

Structural Diversity in Alkali Metal Complexes of Sterically Demanding Carbazol-9-yl Ligands. Moorhouse RS, Moxey GJ, Ortu F, Reade TJ, Lewis W, Blake AJ and Kays DL. 2013. Inorganic Chemistry, 52 (5), 2678-2683.

The Inherent Single-Molecule Magnet Character of Trivalent Uranium, Angew. Moro F, Mills DP, Liddle ST and Van Slageren J. 2013. Chem., 52, 3430–3433.

A triamido-uranium(V) inverse-sandwich 10π-toluene tetraanion arene complex. Patel D, Tuna F, McInnes EJL, McMaster J, Lewis W, Blake AJ and Liddle ST. 2013. Dalton Trans, 42, 5524–5227.

The effect of carbon nanotubes on chiral chemical reactions. Rance GA, Miners SA, Chamberlain TW and Khlobystov AN. 2013. Chemical Physics Letters, 557, 10-14.

Densities of the carbon dioxide plus hydrogen, a system of relevance to carbon capture and storage. Sanchez-Vicente Y, Drage TC, Poliakoff M, Ke J and George MW. 2013. International Journal of Greenhouse Gas Control, 13, 78-86.

Stability and dynamics of vacancy in graphene flakes: Edge effects. Santana A, Popov AM and Bichoutskaia E. 2013. Chemical Physics Letters, 557, 80-87.

Inclusion of radiation damage dynamics in high-resolution transmission electron microscopy image simulations: The example of graphene. Santana A, Zobelli A, Kotakoski J, Chuvilin A and Bichoutskaia E. 2013. Physical Review B, 87 (9).

Accommodation of Lattice Mismatch in a Thiol Self-Assembled Monolayer. She Z, Lahaye D, Champness NR, Buhl M, Hamoudi H, Zharnikov M and Buck M. 2013. Journal of Physical Chemistry C, 117 (9), 4647-4656.

Monolayer to Bilayer Structural Transition in Confined Pyrrolidinium-Based Ionic Liquids. Smith AM, Lovelock KRJ, Gosvami NN, Licence P, Dolan A, Welton T and Perkin S. 2013. Journal of Physical Chemistry Letters, 4 (3), 378-382.

Cellulose Nanowhiskers Templating in Conductive Polymer Nanocomposites Reduces Electrical Percolation Threshold 5-Fold. Tkalya E, Ghislandi M, Thielemans W, van der Schoot P, de With G and Koning C. 2013. Acs Macro Letters, 2 (2), 157-163.

The S349T mutation of SQSTM1 links Keap1/Nrf2 signalling to Paget's disease of bone. Wright T, Rea SL, Goode A, Bennett AJ, Ratajczak T, Long JE, Searle MS, Goldring CE, Park BK, Copple IM and Layfield R. 2013. Bone 2013, 52 (2), 699-706.

Publications 2012

High-Nuclearity Metal-Organic Nanospheres: A Cd66 Ball. Argent SP, Greenaway A, del Carmen Gimenez-Lopez M, Lewis W, Nowell H, Khlobystov AN, Blake AJ, Champness NR and Schroder M. 2012. J. Am. Chem.Soc. 134(55-58).

Surface Modification of Polyethylene with Multi-End-Functional Polyethylene Additives. Hardman SJ, Hutchings LR, Clarke N, Kimani SM, Mears LE, Smith EF, Webster JRP and Thompson RI. 2012. Langmuir 28, (5121-5137).

Chromosomal Replication Initiation Machinery of Low-G plus C-Content Firmicutes. Briggs GS, Smits WK and Soultanas P. 2012 Journal of Bacteriology, 194 (19), 5162-5170.

Loading mechanisms of ring helicases at replication origins. Soultanas P. 2013. Molecular Microbiology, 84 (1), 6-16.

Alkali-metal mediated reactivity of a diaminobromoborane: mono- and bis-borylation of naphthalene versus boryl lithium or hydroborane formation. Robinson S, McMaster J, Lewis W, Blake AJ and Liddle S T. 2012. Chem.Commun., 48, (5769-5771).

Moderating the Acidity of Pb(II)-Water Complexes through the Coordination of Nonaqueous Ligands: A Computational Study. Aitken GDC, Cox H and Stace AJ. 2012. J. Phys. Chem. A (116, 3035-3041).

Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites. Collier C, Machon C, Briggs G, Smitts WK, Soultanas P. 2012. Nucleic Acids Research (40(2), 739-750).

Patent WO 201/106347 A2 Biomolecular Labelling using multifunctional biotin analogues

Patent WO 2010/09233 A1 Pathogen Detector Assay Method and Kit

Archive of Publications

Solubilisation of .alpha.-chymotrypsin by hydrophobic ion pairing in fluorous systems and supercritical carbon dioxide and demonstration of efficient enzyme recycling. Benaissi K, Poliakoff M and Thomas NR. 2010. Green Chemistry (12(1), 54-59).

The UDP-Galp mutase catalyzed isomerization: synthesis and evaluation of 1,4-anhydro-.beta.-D-galactopyranose and its [2.2.2] methylene homolog. Sadeghi-Khomami A, Forcada TJ, Wilson C, Sanders DAR and Thomas NR. 2010. Organic & Biomolecular Chemistry (8(7), 1596-1602).

A concise route to L-azidoamino acids: L-azidoalanine, L-azidohomoalanine and L-azidonorvaline.  Roth S and Thomas NR. 2010. Synlett ((4), 607-609).

Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase. Partha SK, Sadeghi-Khomami A, Slowski K, Kotake T, Thomas NR, Jakeman DL and Sanders DAR. 2010. Journal of Molecular Biology (403(4), 578-590).

TylianouComplementary PCAF–Coenzyme A Mutagenesis: Chemoenzymatic Synthesis of a Novel Enlarged Coenzyme A Analogue and Evaluation of Its Biological Activity. Khim L, Han J, Willetts L, Brady K, Gillece P, Rached ONR and Stylianou E. 2010. ChemBiochem, (11, 2100-2103).

Frederic Stanley Kipping—Pioneer in Silicon Chemistry: His Life & Legacy. Thomas NR. 2010. Silicon.

The Role of Toxin A and Toxin B in Clostridium Difficile Infection. Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A and Minton NP. 2010. Nature Letters.

The Biocompatibility of Apoferritin-Encapsulated PbS Quantum Dots. Turyanska L, Bradshaw TD, Sharpe J, Li M, Mann S, Thomas NR and Patane A. 2009. Small , 5(15), 1738-1741.


Centre for Biomolecular Sciences

University of Nottingham
University Park
Nottingham, NG7 2RD

telephone: +44 (0) 115 846 8001
fax: +44 (0) 115 846 8002
email: CBS Enquiries