K. BOUZINAB, H. S. SUMMERS, M. F. G. STEVENS, C. J. MOODY, N. R. THOMAS, P. GERSHKOVICH, N. WESTON, M. B. ASHFORD, T. D. BRADSHAW and L. TURYANSKA, 2020. Delivery of temozolomide and N3-propargyl analog to brain tumors using an apoferritin nanocage: ACS Appl. Mater. Interfaces ACS Appl. Mater. Interfaces. 12, 12609-12617
H. S. SUMMERS, M. B. FOREITER, W. LEWIS, C. J. MOODY, T. D. BRADSHAW and M. F. G. STEVENS, 2020. Modulation of the acidity of the 8-carboxamide group in the temozolomide family of antitumour imidazo[5,1-d]-1,2,3,5-tetrazines: Arkivoc Arkivoc. 36-45
ROBINSON, H., OATLEY, S. A., ROWEDDER, J. E., SLADE, P., MACDONALD, S. J. F., ARGENT, S. P., HIRST, J. D., MCINALLY, T. and MOODY, C. J., 2020. Late-Stage Functionalization by Chan-Lam Amination: Rapid Access to Potent and Selective Integrin Inhibitors: Chemistry-a European Journal Chemistry-a European Journal. 26(34), 7678-7684 K. BOUZINAB, H. SUMMERS, J. ZHANG, M. F. G. STEVENS, C. J. MOODY, L. TURYANSKA, N. R. THOMAS, P. GERSHKOVICH, M. B. ASHFORD, E. VITTERSO, L. C. D. STORER, R. GRUNDY and T. D. BRADSHAW, 2019. In search of effective therapies to overcome resistance to temozolomide in brain tumours: Cancer Drug Resist. Cancer Drug Resist.. 2, 1018-1031
J. BOEHM, R. DAVIS, C. E. MURAR, T. LI, B. MCCLELAND, S. DONG, H. YAN, J. KERNS, C. J. MOODY, A. J. WILSON, A. P. GRAVES, M. MENTZER, H. QI, J. YONCHUK, J.-P. KOU, J. FOLEY, Y. SANCHEZ, P. L. PODOLIN, B. BOLOGNESE, C. BOOTH-GENTHE, M. GALOP, L. WOLFE, R. CARR and J. F. CALLAHAN, 2019. Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo: Bioorg. Med. Chem. Bioorganic & Medicinal Chemistry. 27, 579-588
GEARY, GEMMA C., NORTCLIFFE, ANDREW, PEARCE, CHRISTOPHER A., HAMZA, DANIEL, JONES, GERAINT and MOODY, CHRISTOPHER J., 2018. Densely functionalised spirocyclic oxetane-piperidine scaffolds for drug discovery BIOORGANIC & MEDICINAL CHEMISTRY. 26(4), 791-797
SANTOS, MARILIA S., NORTCLIFFE, ANDREW, LEWIS, WILLIAM, BRADSHAW, TRACEY D. and MOODY, CHRISTOPHER J., 2018. Synthesis of Highly Substituted 1,2-Diazetidin-3-ones, Small-Ring Scaffolds for Drug Discovery CHEMISTRY-A EUROPEAN JOURNAL. 24(33), 8325-+ COUSIN, DAVID, HUMMERSONE, MARC G., BRADSHAW, TRACEY D., ZHANG, JIHONG, MOODY, CHRISTOPHER J., FOREITER, MAGDALENA B., SUMMERS, HELEN S., LEWIS, WILLIAM, WHEELHOUSE, RICHARD T. and STEVENS, MALCOLM F. G., 2018. Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position MEDCHEMCOMM. 9(3), 545-553 FINNEY, LAURA C., MITCHELL, LORNA J. and MOODY, CHRISTOPHER J., 2018. Visible light mediated oxidation of benzylic sp(3) C-H bonds using catalytic 1,4-hydroquinone, or its biorenewable glucoside, arbutin, as a pre-oxidant GREEN CHEMISTRY. 20(10), 2242-2249 WALES, STEVEN M., MERISOR, ELENA G., ADCOCK, HOLLY V., PEARCE, CHRISTOPHER A., STRUTT, IAN R., LEWIS, WILLIAM, HAMZA, DANIEL and MOODY, CHRISTOPHER J., 2018. Diastereoselective Synthesis of Highly Substituted, Amino- and Pyrrolidino-Tetrahydrofurans as Lead-Like Molecular Scaffolds CHEMISTRY-A EUROPEAN JOURNAL. 24(32), 8233-8239 S. M. WALES, H. V. ADCOCK, W. LEWIS, D. HAMZA and C. J. MOODY, 2018. Nitrogen-bridged, natural product-like octahydrobenzofurans and octahydroindoles: scope and mechanism of bridge-forming reductive amination via caged heteroadamantanes European Journal of Organic Chemistry. 4696-4704
A. D. PRZESLAK, M. INMAN, W. LEWIS and C. J. MOODY, 2018. On the origin of the thiopyrone CTP-431 “unexpectedly” isolated from the marine sponge Cacospongia mycofijiensis: J. Org. Chem. Journal of Organic Chemistry. 83, 10595-10601
MURRAY, A. T., PACKARD, E., NORTCLIFFE, A., LEWIS, W., HAMZA, D., JONES, G. and MOODY, C. J., 2017. Synthesis of Epibatidine Analogues by Pyrrole Diels-Alder Reactions: Rapid Access to Azabicyclo 2.2.1 heptane and 3,8-Diazabicyclo 3.2.1 octane Scaffolds for Library Synthesis European Journal of Organic Chemistry. 2017(1), 138-148 NORTCLIFFE, ANDREW, MILNE, GAVIN D. S., HAMZA, DANIEL and MOODY, CHRISTOPHER J., 2017. Synthesis of 4-aminotetrahydropyran scaffolds for drug discovery BIOORGANIC & MEDICINAL CHEMISTRY. 25(7), 2218-2225
INMAN, MARTYN, DEXTER, HANNAH L and MOODY, CHRISTOPHER J, 2017. Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B. Organic letters. 19, 3454−3457 DEXTER HL, WILLIAMS HE, LEWIS W and MOODY CJ, 2017. Total Synthesis of the Post-translationally Modified Polyazole Peptide Antibiotic Goadsporin. Angewandte Chemie (International ed. in English). 56(11), 3069-3073 NICOLLE, SIMON M., NORTCLIFFE, ANDREW, BARTRUM, HANNAH E., LEWIS, WILLIAM, HAYES, CHRISTOPHER J. and MOODY, CHRISTOPHER J., 2017. C-H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery CHEMISTRY-A EUROPEAN JOURNAL. 23(55), 13623-13627 SALEH, MAYSAA M., LAUGHTON, CHARLES A., BRADSHAW, TRACEY D. and MOODY, CHRISTOPHER J., 2017. Development of a series of bis-triazoles as G-quadruplex ligands (vol 7, pg 47297, 2017) RSC ADVANCES. 7(77), 49056-49056 BLUNT, CHRISTOPHER E., NAWRAT, CHRISTOPHER C., LEBOZEC, LUCILLE, LIUTKUS, MANTAS, LIU, YANG, LEWIS, WILLIAM and MOODY, CHRISTOPHER J., 2016. Oxidative Routes to the Heterocyclic Cores of Benzothiazole Natural Products SYNLETT. 27(1), 37-40 PATEL, ALPA, SHARP, SWEE Y., HALL, KATELAN, LEWIS, WILLIAM, STEVENS, MALCOLM F. G., WORKMAN, PAUL and MOODY, CHRISTOPHER J., 2016. Fused imidazoles as potential chemical scaffolds for inhibition of heat shock protein 70 and induction of apoptosis. Synthesis and biological evaluation of phenanthro[9,10-d]imidazoles and imidazo[4,5-f][1,10]phenanthrolines ORGANIC & BIOMOLECULAR CHEMISTRY. 14(16), 3889-3905 DAVID, NADEGE, PASCERI, RAFFAELE, KITSON, RUSSELL R. A., PRADAL, ALEXANDRE and MOODY, CHRISTOPHER J., 2016. Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement CHEMISTRY-A EUROPEAN JOURNAL. 22(31), 10867-10876 D. M. RAMSEY, R. R. A. KITSON, J. I. LEVIN, C. J. MOODY and S. R. MCALPINE, 2015. Recent advances in macrocyclic Hsp90 inhibitors. In: Macrocycles in Drug Discovery Royal Society of Chemistr. 37-77
MULAS A, WILLENER Y, CARR-SMITH J, JOLY KM, MALE L, MOODY CJ, HORSWELL SL, NGUYEN HV and TUCKER JHR, 2015. The effect of central and planar chirality on the electrochemical and chiral sensing properties of ferrocenyl urea H-bonding receptors. Dalton Transactions. 44(16), 7268-75 NICOLLE SM, LEWIS W, HAYES CJ and MOODY CJ, 2015. Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene OH Insertion Reaction. Angewandte Chemie (International ed. in English). 54(29), 8485-9 PATEL, ALPA, LEWIS, WILLIAM, SEARLE, MARK S., STEVENS, MALCOLM F. G. and MOODY, CHRISTOPHER J., 2015. Synthesis of 6-arylisocytosines and their potential for hydrogen bonding interactions TETRAHEDRON. 71(39), 7339-7343 MOODY, CJ, 2015. Charles Wayne Rees CBE Biographical Memoirs of Fellows of the Royal Society. 61, 351-378
WADA, HIROKI, WILLIAMS, HUW E. L. and MOODY, CHRISTOPHER J., 2015. Total Synthesis of the Posttranslationally Modified Polyazole Peptide Antibiotic Plantazolicin A ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(50), 15147-15151 XIONG, RUI, ZHOU, WENBO, SIEGEL, DAVID, KITSON, RUSSELL R. A., FREED, CURT R., MOODY, CHRISTOPHER J. and ROSS, DAVID, 2015. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T alpha-Synuclein Toxicity: Molecular Pharmacology Molecular Pharmacology. 88(6), 1045-1054 DUTTON BL, KITSON RRA, PARRY-MORRIS S, ROE SM, PRODROMOU C and MOODY CJ, 2014. Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90. Organic & biomolecular chemistry. 12(8), 1328-40 NAWRAT, CHRISTOPHER C. and MOODY, CHRISTOPHER J., 2014. Quinones as Dienophiles in the Diels-Alder Reaction: History and Applications in Total Synthesis ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 53(8), 2056-2077 ANDERSON I, LOW JS, WESTON S, WEINBERGER M, ZHYVOLOUP A, LABOKHA AA, CORAZZA G, KITSON RA, MOODY CJ, MARCELLO A and FASSATI A, 2014. Heat shock protein 90 controls HIV-1 reactivation from latency. Proceedings of the National Academy of Sciences of the United States of America. 111(15), E1528-37 CHANG C, DRECHSEL DA, KITSON RRA, SIEGEL D, YOU Q, BACKOS DS, JU C, MOODY CJ and ROSS D, 2014. 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. Molecular pharmacology. 85(6), 849-57 CARVALHO C, SIEGEL D, INMAN M, XIONG R, ROSS D and MOODY CJ, 2014. Benzofuranquinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis and biological evaluation. Organic & biomolecular chemistry. 12(17), 2663-74 JOLIBOIS AER, LEWIS W and MOODY CJ, 2014. Total synthesis of (±)-distomadines A and B. Organic letters. 16(4), 1064-7 GIALLOMBARDO, DANIELE, NEVIN, ADAM C., LEWIS, WILLIAM, NAWRAT, CHRISTOPHER C., KITSON, RUSSELL R. A. and MOODY, CHRISTOPHER J., 2014. Synthesis of toxyloxanthone B TETRAHEDRON. 70(6), 1283-1288 INMAN M, VISCONTI A, YAN C, SIEGEL D, ROSS D and MOODY CJ, 2014. Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells. Organic & biomolecular chemistry. 12(27), 4848-61 R. R. A. KITSON and C. J. MOODY, 2014. Ethyl 2-acetamido acrylate. In: e-EROS Encyclopedia of Reagents for Organic Synthesis 1-3
K. WALSH, H. F. SNEDDON and C. J. MOODY, 2014. Sustainable, mild and efficient p-methoxybenzyl ether deprotections utilizing catalytic DDQ Tetrahedron. 70, 7380-7387
K. WALSH, H. F. SNEDDON and C. J. MOODY, 2014. An efficient method for the synthesis of heteroaryl C-O bonds in the absence of added transition metal catalysts RSC Advances. 4, 28072 – 28077
M. A. HONEY and C. J. MOODY, 2014. Synthesis of indoxylic acid esters by rhodium-catalyzed carbene N-H insertion and thermal cyclization Australian Journal of Chemistry. 67, 1211-1216
INMAN, MARTYN and MOODY, CHRISTOPHER J., 2013. Indole synthesis - something old, something new CHEMICAL SCIENCE. 4(1), 29-41 KITSON, R.R.A., CHANG, C.-H., XIONG, R., WILLIAMS, H.E.L., DAVIS, A.L., LEWIS, W., DEHN, D.L., SIEGEL, D., ROE, S.M., PRODROMOU, C., ROSS, D. and MOODY, C.J., 2013. Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90 Nature Chemistry. 5(4), 307-314 BARTRUM, HANNAH E., BLAKEMORE, DAVID C., MOODY, CHRISTOPHER J. and HAYES, CHRISTOPHER J., 2013. Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions: synthesis of alpha-sulfanyl, alpha-sulfonyl, and alpha-phosphono carboxylates TETRAHEDRON. 69(10), 2276-2282 NEWSOME, JEFFERY J., HASSANI, MARY, SWANN, ELIZABETH, BIBBY, JANE M., BEALL, HOWARD D. and MOODY, CHRISTOPHER J., 2013. Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: Excellent substrates for NAD(P)H:quinone oxidoreductase 1 BIOORGANIC & MEDICINAL CHEMISTRY. 21(11), 2999-3009 PASCERI, RAFFAELE, SIEGEL, DAVID, ROSS, DAVID and MOODY, CHRISTOPHER J., 2013. Aminophenoxazinones as Inhibitors of Indoleamine 2,3-Dioxygenase (IDO). Synthesis of Exfoliazone and Chandrananimycin A JOURNAL OF MEDICINAL CHEMISTRY. 56(8), 3310-3317 NAWRAT, CHRISTOPHER C., PALMER, LEONI I., BLAKE, ALEXANDER J. and MOODY, CHRISTOPHER J., 2013. Two Approaches to the Aromatic Core of the Aminonaphthoquinone Antibiotics JOURNAL OF ORGANIC CHEMISTRY. 78(11), 5587-5603 KITSON, RUSSELL R. A. and MOODY, CHRISTOPHER J., 2013. Learning from Nature: Advances in Geldanamycin- and Radicicol-Based Inhibitors of Hsp90 JOURNAL OF ORGANIC CHEMISTRY. 78(11), 5117-5141 INMAN M and MOODY CJ, 2013. Copper(II)-Mediated Synthesis of Indolequinones from Bromoquinones and Enamines. European journal of organic chemistry. 2013(11), 2179-2187 GEORGE, IAN R., LEWIS, WILLIAM and MOODY, CHRISTOPHER J., 2013. Synthesis of lodopyridone TETRAHEDRON. 69(38), 8209-8215 WILSON AJ, KERNS JK, CALLAHAN JF and MOODY CJ, 2013. Keap Calm, and Carry on Covalently. Journal of medicinal chemistry. 56(19), 7463-7476 MITCHELL, LORNA J., LEWIS, WILLIAM and MOODY, CHRISTOPHER J., 2013. Solar photochemistry: optimisation of the photo Friedel-Crafts acylation of naphthoquinones GREEN CHEMISTRY. 15(10), 2830-2842 HONEY MA, PASCERI R, LEWIS W and MOODY CJ, 2012. Diverse Trifluoromethyl Heterocycles From A Single Precursor. The Journal Of Organic Chemistry. 77(3), 1396-405 NAWRAT, CC and MOODY, CJ, 2012. Total synthesis of mevashuntin Organic Letters. 14(6), 1484-1487 CARBONE A, LUCAS CL and MOODY CJ, 2012. Biomimetic synthesis of the apoptosis-inducing thiazinoquinone thiaplidiaquinone A. The Journal of organic chemistry. 77(20), 9179-89 PASCERI R, BARTRUM HE, HAYES CJ and MOODY CJ, 2012. Nucleophilic fluorination of β-ketoester derivatives with HBF4. Chemical communications (Cambridge, England). 48(99), 12077-9 DUFOUR, M., YAN, C., SIEGEL, D., COLUCCI, M.A., JENNER, M., OLDHAM, N.J., GOMEZ, J., REIGAN, P., LI, Y., DE MATTEIS, C.I., ROSS, D. and MOODY, C.J., 2011. Mechanism-based inhibition of quinone reductase 2 (NQO2): selectivity for NQO2 over NQO1 and structural basis for flavoprotein inhibition ChemBioChem. 12(8), 1203-1208 BUTT, NICHOLAS A and MOODY, CHRISTOPHER J, 2011. Synthesis of Spirotetramates via a Diels-Alder Approach. Organic letters. 13(9), 2224-7 BARTRUM, HANNAH E, BLAKEMORE, DAVID C, MOODY, CHRISTOPHER J and HAYES, CHRISTOPHER J, 2011. Rapid Access to α-Alkoxy and α-Amino Acid Derivatives through Safe Continuous-Flow Generation of Diazoesters. Chemistry (Weinheim an der Bergstrasse, Germany).
LINDER, J., GARNER, T.P., WILLIAMS, H.E.L., SEARLE, M.S. and MOODY, C.J., 2011. Telomestatin: formal total synthesis and cation-mediated interaction of its seco-derivatives with G-quadruplexes Journal of the American Chemical Society. 133(4), 1044-1051 YAN, CHAO, DUFOUR, MARINE, SIEGEL, DAVID, REIGAN, PHILIP, GOMEZ, JOE, SHIEH, BIEHUOY, MOODY, CHRISTOPHER J and ROSS, DAVID, 2011. Indolequinone Inhibitors of NRH:Quinone Oxidoreductase 2. Characterization of the Mechanism of Inhibition in both Cell-Free and Cellular Systems. Biochemistry. 50(31), 6678-88 BATTAGLIA, U., LONG, J., SEARLE, M. and MOODY, C., 2011. 7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine ORGANIC AND BIOMOLECULAR CHEMISTRY. VOL 9(NUMBER 7), 2227-2232 SMITH, MARCUS J, NAWRAT, CHRISTOPHER C and MOODY, CHRISTOPHER J, 2011. Synthesis of Parvistemin A via Biomimetic Oxidative Dimerization. Organic letters. 13(13), 3396-8 INMAN, MARTYN and MOODY, CHRISTOPHER J, 2011. A two step route to indoles from haloarenes--a versatile variation on the Fischer indole synthesis. Chemical communications (Cambridge, England). 47(2), 788-90
NAWRAT, CHRISTOPHER C and MOODY, CHRISTOPHER J, 2011. Natural products containing a diazo group. Natural product reports. 28(8), 1426-1444 PADWAL, J, LEWIS, W and MOODY, CJ, 2011. Synthesis Of Balsaminone A, A Naturally Occurring Pentacyclic Dinaphthofuran Quinone Journal Of Organic Chemistry. 76(19), 8082-8087 DAY, J.E.H., SHARP, S.Y., ROWLANDS, M.G., AHERNE, W., HAYES, A., RAYNAUD, F.I., LEWIS, W., ROE, S.M., PRODROMOU, C., PEARL, L.H., WORKMAN, P. and MOODY, C.J., 2011. Targeting the Hsp90 molecular chaperone with novel macrolactams: synthesis, structural, binding, and sellular studies ACS Chemical Biology. 6(12), 1339–1347 SHI, BAOLU, BLAKE, ALEXANDER J, LEWIS, WILLIAM, CAMPBELL, IAN B, JUDKINS, BRIAN D and MOODY, CHRISTOPHER J, 2010. Rhodium carbene routes to oxazoles and thiazoles. Catalyst effects in the synthesis of oxazole and thiazole carboxylates, phosphonates, and sulfones. Journal of Organic Chemistry. 75(1), 152-61 DAY, JAMES E H, SHARP, SWEE Y, ROWLANDS, MARTIN G, AHERNE, WYNNE, LEWIS, WILLIAM, ROE, S MARK, PRODROMOU, CHRISOSTOMOS, PEARL, LAURENCE H, WORKMAN, PAUL and MOODY, CHRISTOPHER J, 2010. Inhibition of Hsp90 with resorcylic acid macrolactones: synthesis and binding studies. Chemistry - A European Journal. 16(34), 10366-72 BRUDER, MARJORIE, HASELER, PAUL L, MUSCARELLA, MARINA, LEWIS, WILLIAM and MOODY, CHRISTOPHER J, 2010. Synthesis of the oxepinochromone natural products ptaeroxylin (desoxykarenin), ptaeroxylinol, and eranthin. Journal of Organic Chemistry. 75(2), 353-8 DAY, JAMES E H, SHARP, SWEE Y, ROWLANDS, MARTIN G, AHERNE, WYNNE, WORKMAN, PAUL and MOODY, CHRISTOPHER J, 2010. Targeting the Hsp90 chaperone: synthesis of novel resorcylic acid macrolactone inhibitors of Hsp90. Chemistry - A European Journal. 16(9), 2758-63 BATTAGLIA, U. and MOODY, C.J., 2010. A Short Synthesis of the Triazolopyrimidine Antibiotic Essramycin JOURNAL OF NATURAL PRODUCTS. VOL 73(NUMB 11), 1938-1939 JOLY, KÉVIN M, MIRRI, GIORGIO, WILLENER, YASMINE, HORSWELL, SARAH L, MOODY, CHRISTOPHER J and TUCKER, JAMES H R, 2010. Synthesis of an achiral isomer of lipoic acid as an anchor group for SAM formation on gold surfaces. Journal of Organic Chemistry. 75(7), 2395-8
BARTRUM, HANNAH E, BLAKEMORE, DAVID C, MOODY, CHRISTOPHER J and HAYES, CHRISTOPHER J, 2010. Synthesis of β-keto esters in-flow and rapid access to substituted pyrimidines. The Journal of organic chemistry. 75(24), 8674-6 INMAN, MARTYN and MOODY, CHRISTOPHER J, 2010. Synthesis of indolequinones from bromoquinones and enamines mediated by Cu(OAc)2.H2O. Journal of Organic Chemistry. 75(17), 6023-6 SMITH, MATTHEW R, BLAKE, ALEXANDER J, HAYES, CHRISTOPHER J, STEVENS, MALCOLM F G and MOODY, CHRISTOPHER J, 2009. Carbene reactivity of 4-diazo-4H-imidazoles toward nucleophiles and aromatic compounds. Journal of Organic Chemistry. 74(24), 9372-80
SHI, BAOLU, BLAKE, ALEXANDER J, CAMPBELL, IAN B, JUDKINS, BRIAN D and MOODY, CHRISTOPHER J, 2009. The rhodium carbene route to oxazoles: a remarkable catalyst effect. Chemical Communications. 3291-3 DAY, J.E.H., BLAKE, A.J. and MOODY, C.J., 2009. An Improved Synthesis of Resorcylic Acid Macrolactone Inhibitors of Hsp90 Synlett. NUMB 10, 1567-1570
SHI, BAOLU, LEWIS, WILLIAM, CAMPBELL, IAN B and MOODY, CHRISTOPHER J, 2009. A concise route to pyridines from hydrazides by metal carbene N-H insertion, 1,2,4-triazine formation, and Diels-Alder reaction. Organic Letters. 11(16), 3686-8 HONEY, M. A., BLAKE, A. J., CAMPBELL, I. B., JUDKINS, B. D. and MOODY, C. J., 2009. One-pot synthesis of N-methylindoles from N-methylanilines and of benzofurans from phenols using transition-metal carbene X-H insertion reactions Tetrahedron. VOL 65(NUMBER 44), 8995-9001 LE BOZEC, L. and MOODY, C.J., 2009. Naturally Occurring Nitrogen-Sulfur Compounds. The Benzothiazole Alkaloids Australian Journal of Chemistry. VOL 62(NUMB 7), 639-647 BLANCHE, E. A., MASKELL, L., COLUCCI, M. A., WHATMORE, J. L. and MOODY, C. J., 2009. Synthesis of potential prodrug systems for reductive activation. Prodrugs for anti-angiogenic isoflavones and VEGF receptor tyrosine kinase inhibitory oxindoles Tetrahedron. VOL 65(NUMBER 25), 4894-4903 YAN, CHAO, SHIEH, BIEHUOY, REIGAN, PHILIP, ZHANG, ZHIYONG, COLUCCI, MARIE A, CHILLOUX, AURÉLIE, NEWSOME, JEFFERY J, SIEGEL, DAVID, CHAN, DAN, MOODY, CHRISTOPHER J and ROSS, DAVID, 2009. Potent activity of indolequinones against human pancreatic cancer: identification of thioredoxin reductase as a potential target. Molecular Pharmacology. 76(1), 163-72 COUCH, G. D., BURKE, P. J., KNOX, R. J. and MOODY, C. J., 2008. Synthesis of 2-aryl-6-methyl-5-nitroquinoline derivatives as potential prodrug systems for reductive activation TETRAHEDRON -LONDON-. VOL 64(NUMBER 12), 2816-2823
BRUDER, M. and MOODY, C.J., 2008. Synthesis of (+/-)-Smenochromene D (Likonide B) Using a Regioselective Claisen Rearrangement SYNLETT. NUMB 4, 575-577
HURST, T. E., MILES, T. J. and MOODY, C. J., 2008. Intramolecular Diels-Alder reactions of a,b-unsaturated oxime ethers as 1-azadienes: synthesis of [c]-fused pyridines TETRAHEDRON -LONDON-. VOL 64(NUMBER 5), 874-882
LINDER, JÖRG, BLAKE, ALEXANDER J and MOODY, CHRISTOPHER J, 2008. Total synthesis of siphonazole and its O-methyl derivative, structurally unusual bis-oxazole natural products. Organic & biomolecular chemistry. 6(21), 3908-16
KIRKMAN, JOSEPH K, LINDELL, STEPHEN D, MAECHLING, SIMON, SLAWIN, ALEXANDRA M Z and MOODY, CHRISTOPHER J, 2008. Synthesis of 3-(carboxyarylalkyl)imidazo[2,1-f][1,2,4]triazines as potential inhibitors of AMP deaminase. Organic & biomolecular chemistry. 6(23), 4452-9
WILLENER, YASMINE, JOLY, KÉVIN M, MOODY, CHRISTOPHER J and TUCKER, JAMES H R, 2008. An exploration of ferrocenyl ureas as enantioselective electrochemical sensors for chiral carboxylate anions. Journal of Organic Chemistry. 73(4), 1225-33 COOMBES, CATHERINE L and MOODY, CHRISTOPHER J, 2008. First syntheses of 2,2-dimethyl-7-(2'-methylbut-3'-en-2'-yl)-2H-chromen-6-ol and 2-(3'-methylbut-2'-enyl)-5-(2'-methylbut-3'-en-2'-yl)-1,4-benzoquinone, novel prenylated quinone derivatives from the New Zealand brown alga Perithalia capillaris. The Journal of organic chemistry. 73(17), 6758-62
MUSCARELLA, M., KIMBER, M.C. and MOODY, C.J., 2008. Synthesis of Ptaeroxylin (Desoxykarenin): An Unusual Chromone from the Sneezewood Tree Ptaeroxylon obliquum SYNLETT. NUMB 14, 2101-2102
JOLY, KÉVIN M, WILSON, CLAIRE, BLAKE, ALEXANDER J, TUCKER, JAMES H R and MOODY, CHRISTOPHER J, 2008. Competition between planar and central chiral control elements in nucleophilic addition to ferrocenyl imine derivatives. Chemical Communications. 5191-3 MCERLEAN, C. S., SPERRY, J., BLAKE, A. J. and MOODY, C. J., 2007. Synthesis of the calothrixins, pentacyclic indolo[3,2-j]phenanthridine alkaloids, using a biomimetic approach TETRAHEDRON -LONDON-. VOL 63(NUMBER 45), 10963-10970
SPERRY, J., MCERLEAN, C. S., SLAWIN, A. M. and MOODY, C. J., 2007. A biomimetic synthesis of calothrixin B TETRAHEDRON LETTERS. VOL 48(NUMBER 2), 231-234 TADDEI, D., PORIEL, C. and MOODY, C.J., 2007. An expedient approach to the 2,3,5,6-tetrasubstituted pyridine core of nosiheptide using oxidative cleavage of 2,3,5,8-tetrasubstituted quinolines Arkivoc. 56-63
NEWSOME, J. J., SWANN, E., HASSANI, M., BRAY, K. C., SLAWIN, A. M., BEALL, H. D. and MOODY, C. J., 2007. Indolequinone antitumour agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase ORGANIC AND BIOMOLECULAR CHEMISTRY. VOL 5(NUMBER 10), 1629-1640 MASKELL, L., BLANCHE, E. A., COLUCCI, M. A., WHATMORE, J. L. and MOODY, C. J., 2007. Synthesis and evaluation of prodrugs for anti-angiogenic pyrrolylmethylidenyl oxindoles BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. VOL 17(NUMBER 6), 1575-1578 MOODY, C.J., 2007. Enantioselective carbene N–H insertion: a potentially versatile route for the asymmetric synthesis of amine derivatives Angew. Chem. Int. Ed.. 46, 9148-9150 (In Press.)
MCERLEAN, CHRISTOPHER S P, PROISY, NICOLAS, DAVIS, CHRISTOPHER J, BOLAND, NICOLA A, SHARP, SWEE Y, BOXALL, KATHY, SLAWIN, ALEXANDRA M Z, WORKMAN, PAUL and MOODY, CHRISTOPHER J, 2007. Synthetic ansamycins prepared by a ring-expanding Claisen rearrangement. Synthesis and biological evaluation of ring and conformational analogues of the Hsp90 molecular chaperone inhibitor geldanamycin. Organic & biomolecular chemistry. 5(3), 531-46 HUGHES, RACHAEL A and MOODY, CHRISTOPHER J, 2007. From amino acids to heteroaromatics--thiopeptide antibiotics, nature's heterocyclic peptides. Angewandte Chemie International Edition. 46(42), 7930-54 PORIEL, CYRIL, LACHIA, MATHILDE, WILSON, CLAIRE, DAVIES, JAMES R and MOODY, CHRISTOPHER J, 2007. Oxidative rearrangement of indoles: a new approach to the EFHG-tetracyclic core of diazonamide A. Journal of Organic Chemistry. 72(8), 2978-87 COLUCCI, M.A., REIGAN, P., SIEGEL, D., CHILLOUX, A., ROSS, D. and MOODY, C.J., 2007. Synthesis and Evaluation of 3-Aryloxymethyl-1,2-dimethylindole-4,7-diones as Mechanism-Based Inhibitors of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Activity JOURNAL OF MEDICINAL CHEMISTRY. VOL 50(NUMB 23), 5780-5789 REIGAN, PHILIP, COLUCCI, MARIE A, SIEGEL, DAVID, CHILLOUX, AURÉLIE, MOODY, CHRISTOPHER J and ROSS, DAVID, 2007. Development of Indolequinone Mechanism-Based Inhibitors of NAD(P)H:Quinone Oxidoreductase 1 (NQO1): NQO1 Inhibition and Growth Inhibitory Activity in Human Pancreatic MIA PaCa-2 Cancer Cells. Biochemistry. 46(20), 5941-50 NEWSOME, JEFFERY J, COLUCCI, MARIE A, HASSANI, MARY, BEALL, HOWARD D and MOODY, CHRISTOPHER J, 2007. Benzimidazole- and benzothiazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1. Organic and Biomolecular Chemistry. 5(22), 3665-73 PROISY, N., SHARP, S.Y., BOXALL, K., CONNELLY, S., ROE, S.M., PRODROMOU, C., SLAWIN, A.M.Z., PEARL, L.H., WORKMAN, P. and MOODY, C.J., 2006. Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol Chemistry & Biology. 13(11), 1203-1215 D. L. DEHN, D. SIEGEL, K. S. ZAFAR, P. REIGAN, E. SWANN, C. J. MOODY AND D. ROSS, 2006. 5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo Molecular Cancer Therapeutics. 5, 1701-1709 LEWIS, R. J., HUGHES, R. A., ALCARAZ, L., THOMPSON, S. P. and MOODY, C. J., 2006. Solution structures of thiopeptide antibiotics Chemical Communications. VOL 2006(NUMBER 40), 4215-4217 BENTLEY, D. J., SLAWIN, A. M. Z. and MOODY, C. J., 2006. Total Synthesis of Stephanotic Acid Methyl Ester Organic Letters. VOL 8(NUMB 10), 1975-1978 HUGHES, R.A., THOMPSON, S.P., ALCARAZ, L. and MOODY, C.J., 2005. Total synthesis of the thiopeptide antibiotic amythiamicin D Journal of the American Chemical Society. 127(44), 15644-15651 DAVIES, J. R., KANE, P. D. and MOODY, C. J., 2005. The Diazo Route to Diazonamide A. Studies on the Indole Bis-oxazole Fragment Journal of Organic Chemistry. VOL 70(NUMB 18), 7305-7316 COOPER, T. S., LARIGO, A. S., LAURENT, P., MOODY, C. J. and TAKLE, A. K., 2005. Chiral oxime ethers in asymmetric synthesis. O-(1-Phenylbutyl)-benzyloxyacetaldoxime, a versatile reagent for the asymmetric synthesis of protected 1,2-aminoalcohols, alpha-amino acid derivatives, and 2-hydroxymethyl nitrogen heterocycles including iminosugars Organic and Biomolecular Chemistry. VOL 3(NUMB 7), 1252-1262 PALMER, F. N., LACH, F., PORIEL, C., PEPPER, A. G., BAGLEY, M. C., SLAWIN, A. M. Z. and MOODY, C. J., 2005. The diazo route to diazonamide A: studies on the tyrosine-derived fragment Organic and Biomolecular Chemistry. VOL 3(NUMB 20), 3805-3811 WINYARD, P. G., MOODY, C. J. and JACOB, C., 2005. Oxidative activation of antioxidant defence Trends in Biochemical Sciences. VOL 30(NUMBER 8), 453-461 DAVIES, J. R., KANE, P. D. and MOODY, C. J., 2004. N-H Insertion reactions of rhodium carbenoids. Part 5: A convenient route to 1,3-azoles Tetrahedron. VOL 60(NUMBER 18), 3967-3977 FRYATT, T., PETTERSSON, H. I., GARDIPEE, W. T., BRAY, K. C., GREEN, S. J., SLAWIN, A. M., BEALL, H. D. and MOODY, C. J., 2004. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1) Bioorganic and Medicinal Chemistry. VOL 12(NUMBER 7), 1667-1687 VIGUSHIN, D. M., MIRSAIDI, N., BROOKE, G., SUN, C., PACE, P., INMAN, L., MOODY, C. J. and COOMBES, R. C., 2004. Gliotoxin Is a Dual Inhibitor of Farnesyltransferase and Geranylgeranyltransferase I with Antitumor Activity Against Breast Cancer In Vivo Medical Oncology. VOL 21(PART 1), 21-30 BENTLEY, D. J. and MOODY, C. J., 2004. Asymmetric synthesis of the central tryptophan residue of stephanotic acid Organic and Biomolecular Chemistry. VOL 2(NUMB 24), 3545-3547 HUGHES, R. A., THOMPSON, S. P., ALCARAZ, L. and MOODY, C. J., 2004. Total synthesis of the thiopeptide amythiamicin D Chemical Communications. PART 8, 946-949
BENTLEY, D. J., FAIRHURST, J., GALLAGHER, P. T., MANTEUFFEL, A. K., MOODY, C. J. and PINDER, J. L., 2004. Synthesis of the 2,3,4-trisubstituted indole fragments of nosiheptide and glycothiohexide Organic and Biomolecular Chemistry. VOL 2(NUMB 5), 701-708 VIGUSHIN, D. M., BROOKE, G., WILLOWS, D., COOMBES, R. C. and MOODY, C. J., 2003. Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I Bioorganic and Medicinal Chemistry Letters. VOL 13(NUMBER 21), 3661-3663 BASHFORD, K. E., BURTON, M. B., CAMERON, S., COOPER, A. L., HOGG, R. D., KANE, P. D., MACMANUS, D. A., MATRUNOLA, C. A., MOODY, C. J. and ROBERTSON, A. A. B., 2003. The Bohlmann-Rahtz route to functionalised pyridine scaffolds and their use in library synthesis Tetrahedron Letters. VOL 44(PART 8), 1627-1630 DEHN, D. L., SIEGEL, D., SWANN, E., MOODY, C. J. and ROSS, D., 2003. Biochemical, Cytotoxic, and Genotoxic Effects of ES936, a Mechanism-Based Inhibitor of NAD(P)H:quinone Oxidoreductase 1, in Cellular Systems Molecular Pharmacology. VOL 64(PART 3), 714-720 BUCK, R. T., COE, D. M., DRYSDALE, M. J., FERRIS, L., HAIGH, D., MOODY, C. J., PEARSON, N. D. and SANGHERA, J. B., 2003. Asymmetric rhodium carbene insertion into the SiH bond: identification of new dirhodium(II) carboxylate catalysts using parallel synthesis techniques Tetrahedron Asymmetry. VOL 14(NUMBER 7), 791-816 DAVIS, C. J. and MOODY, C. J., 2002. The Claisen Rearrangement Followed by Phenol Oxidation: A Simple Route to Naturally Occurring Benzoquinones Including an Ansa-Bridged Derivative Related to the Ansamycin Antibiotics Synlett. PART 11, 1874-1876
BUCK, R.T., MOODY, C.J. and PEPPER, A.G., 2002. N-H Insertion reactions of rhodium carbenoids. Part 4. New chiral dirhodium(II) carboxylate catalysts Arkivoc. 16-32.
BASHFORD, K. E., COOPER, A. L., KANE, P. D. and MOODY, C. J., 2002. A new protecting-group strategy for indoles Tetrahedron Letters. VOL 43(PART 1), 135-138 LAURENT, PIERRE, MIYAJI, HIDEKAZU, COLLINSON, SIMON R, PROKES, IVAN, MOODY, CHRISTOPHER J, TUCKER, JAMES H R and SLAWIN, ALEXANDRA M Z, 2002. Asymmetric synthesis of chiral alpha-ferrocenylalkylamines and their use in the preparation of chiral redox-active receptors. Organic Letters. 4(23), 4037-40 MOODY, C. J. and PALMER, F. N., 2002. Dirhodium(II) carboxylate-catalysed oxidation of allylic and benzylic alcohols Tetrahedron Letters. VOL 43(PART 1), 139-142 BASHFORD, K. E., COOPER, A. L., KANE, P. D., MOODY, C. J., MUTHUSAMY, S. and SWANN, E., 2002. N-H Insertion reactions of rhodium carbenoids. Part 3. The development of a modified Bischler indole synthesis and a new protecting-group strategy for indoles Perkin 1. PART 14, 1672-1687
EVERETT, S. A., SWANN, E., NAYLOR, M. A., STRATFORD, M. R., PATEL, K. B., TIAN, N., NEWMAN, R. G., VOJNOVIC, B., MOODY, C. J. and WARDMAN, P., 2002. Modifying rates of reductive elimination of leaving groups from indolequinone prodrugs: a key factor in controlling hypoxia-selective drug release Biochemical Pharmacology. VOL 63(NUMBER 9), 1629-1639 BLOXHAM, J., MOODY, C. J. and SLAWIN, A. M., 2002. Synthesis and solid state structures of N,Nprime-linked carbazoles and indoles Tetrahedron. VOL 58(NUMBER 19), 3709-3720 COOPER, T. S., LARIGO, A. S., LAURENT, P., MOODY, C. J. and TAKLE, A. K., 2002. O-(1-Phenylbutyl)benzyloxyacetaldoxime, a Versatile Reagent for the Asymmetric Synthesis of Protected 1,2-Aminoalcohols and 2-Hydroxymethyl Nitrogen Heterocycles Synlett. PART 10, 1730-1732
WHATMORE, JACQUELINE L, SWANN, ELIZABETH, BARRAJA, PAOLA, NEWSOME, JEFFERY J, BUNDERSON, MELISA, BEALL, HOWARD D, TOOKE, JOHN E and MOODY, CHRISTOPHER J, 2002. Comparative study of isoflavone, quinoxaline and oxindole families of anti-angiogenic agents. Angiogenesis. 5(1-2), 45-51
PITTS, M.R., HARRISON, J.R. and MOODY, C.J., 2001. Indium metal as a reducing agent in organic synthesis Perkin 1: an international journal of organic and bio-organic chemistry. 9, 955-977 WINSKI, S.L., FAIG, M., BIANCHET, M.A., SIEGEL, D., SWANN, E., FUNG, K., DUNCAN, M.W., MOODY, C.J., AMZEL, L.M. and ROSS, D., 2001. Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches Biochemistry. 40(50), 15135-15142 MOODY, C. J., MORFITT, C. N. and SLAWIN, A. M., 2001. Preparation of chiral a-diazophosphonic acid derivatives Tetrahedron Asymmetry. VOL 12(NUMBER 11), 1657 - 1661 WINSKI, S. L., SWANN, E., HARGREAVES, R. H., DEHN, D. L., BUTLER, J., MOODY, C. J. and ROSS, D., 2001. Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones BIOCHEMICAL PHARMACOLOGY. VOL 61(NUMBER 12), 1509-1516 E. SWANN, C. J. MOODY, M. R. L. STRATFORD, K. B. PATEL, M. A. NAYLOR, B. VOJNOVIC, P. WARDMAN, S. A. EVERETT, 2001. Rates of reductive elimination of substituted nitrophenols from the (indol–3–yl)methyl position of indolequinones J. Chem. Soc., Perkin Trans. 2. 1340-1345 SWANN, E., BARRAJA, P., OBERLANDER, A. M., GARDIPEE, W. T., HUDNOTT, A. R., BEALL, H. D. and MOODY, C. J., 2001. Indolequinone Antitumor Agents: Correlation between Quinone Structure and Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase. Part 2 Journal of Medicinal Chemistry. VOL 44(PART 20), 3311-3319 BUSHBY, N., MOODY, C. J., RIDDICK, D. A. and WALDRON, I. R., 2001. Double intramolecular hetero Diels-Alder reactions of alpha,beta-unsaturated hydrazones as 1-azadienes: a new route to 2,2'-bipyridines Perkin 1. PART 18, 2183-2193
FAIG, M., BIANCHET, M. A., WINSKI, S., HARGREAVES, R., MOODY, C. J., HUDNOTT, A. R., ROSS, D. and AMZEL, L. M., 2001. Structure-Based Development of Anticancer Drugs: Complexes of NAD(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones Structure. VOL 9(PART 8), 659-668 DOYLE, M. P., HU, W., PHILLIPS, I. M., MOODY, C. J., PEPPER, A. G. and SLAWIN, A. M. Z., 2001. Reactivity Enhancement for Chiral Dirhodium(II) Tetrakis(Carboxamidates) ADVANCED SYNTHESIS AND CATALYSIS. VOL 343(PART 1), 112-117 EVERETT, S. A., NAYLOR, M. A., BARRAJA, P., SWANN, E., PATEL, K. B., STRATFORD, M. R. L., HUDNOTT, A. R., VOJNOVIC, B., LOCKE, R. J. and WARDMAN, P., 2001. Controlling the rates of reductively-activated elimination from the (indol-3-yl)methyl position of indolequinones PERKIN 2. PART 5, 843-860
MOODY, C.J. and ROFFEY, J.R., 2000. Synthesis of N-protected nortopsentins B and D Arkivoc. 1, 393-401
BAGLEY, M. C., BASHFORD, K. E., HESKETH, C. L. and MOODY, C. J., 2000. Total Synthesis of the Thiopeptide Promothiocin A Journal of the American Chemical Society. VOL 122(PART 14), 3301-3313 HARRISON, J. R., MOODY, C. J. and PITTS, M. R., 2000. Indium as a Reducing Agent: Reduction of Oximes Synlett. PART 11, 1601-1602
BAGLEY, M. C., HIND, S. L. and MOODY, C. J., 2000. Studies towards the synthesis of diazonamide A. Synthesis of the indole bis-oxazole fragment Tetrahedron Letters. VOL 41(PART 35), 6897-6900 MOODY, C.J., HUNT, P.A. and SMITH, C., 2000. Iodocyclisation of N-Allyl Ureas; a Route to Imidazolin-2-ones Arkivoc. 1, 698-706
MOODY, C. J. and HUNT, J. C. A., 1999. Synthesis of Virenamide B, a Cytotoxic Thiazole-Containing Peptide Journal of Organic Chemistry. VOL 64(NUMBER 23), 8715-8717 MOODY, C. J. and HUNT, J. C. A., 1999. Addition of 2-Lithiothiazoles to ROPHy/SOPHy Aldoximes: Asymmetric Synthesis of 1-(2-Thiazolyl)ethylamines Synlett. SPI, 984-986
FRYATT, T., GOROSKI, D.T., NILSON, Z.D., MOODY, C.J. and BEALL, H.D., 1999. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1) Bioorganic and Medicinal Chemistry Letters. VOL 9(NUMBER 15), 2195-2198 MOODY, C. J., ROFFEY, J. R. A., SWANN, E., LOCKYER, S., HOULBROOK, S. and STRATFORD, I. J., 1999. Synthesis and cytotoxic activity of thiazolyl indolequinones ANTICANCER DRUGS. VOL 10(NUMBER 6), 577-590 MOODY, C. J. and PITTS, M. R., 1999. Indium as a Reducing Agent: Deprotection of 4-Nitrobenzyl Ethers and Esters Synlett. NUMBER 10, 1575-1576
HUNT, J. C. A., LLOYD, C., MOODY, C. J., SLAWIN, A. M. Z. and TAKLE, A. K., 1999. Chiral oxime ethers in asymmetric synthesis. Part 4. Asymmetric synthesis of N-protected amines and á-amino acids by the addition of organometallic reagents to ROPHy/SOPHy-derived aldoximes Perkin Transactions 1. NUMBER 23, 3443-3454
BUSHBY, N., MOODY, C. J., RIDDICK, D. A. and WALDRON, L. R., 1999. Double intramolecular Diels-Alder reaction of à,á-unsaturated hydrazones: a new route to 2,2'-bipyridines Chemical Communications. NUMBER 9, 793-794 MOODY, C. J. and BAGLEY, M. C., 1998. Total synthesis of (+)-nostocyclamide Perkin Transactions 1. NUMBER 3, 601-608
BEALL, H. D., WINSKI, S., SWANN, E., HUDNOTT, A. R., COTTERILL, A. S., O'SULLIVAN, N., GREEN, S. J., BIEN, R., SIEGEL, D. and ROSS, D., 1998. Indolequinone Antitumor Agents: Correlation between Quinone Structure, Rate of Metabolism by Recombinant Human NAD(P)H:Quinone Oxidoreductase, and in Vitro Cytotoxicity Journal of Medicinal Chemistry. VOL 41(NUMBER 24), 4755-4766 MOODY, C. J. and PITTS, M. R., 1998. Indium as a Reducing Agent: Reduction of Aromatic Nitro Groups Synlett. NUMBER 9, 1028
MOODY, C. J., NORTON, C. L., SLAWIN, A. M. Z. and TAYLOR, S., 1998. Cyclopropyl indolequinones: mechanistic probes for bioreductive anticancer drug action Anti-Cancer Drug Design. VOL 13(NUMBER 6), 611-634
BUCK, R. T., COE, D. M., DRYSDALE, M. J., MOODY, C. J. and PEARSON, N. D., 1998. Parallel Synthesis Techniques in the Identification of New Chiral Dirhodium(II) Carboxylates for Asymmetric Carbenoid Insertion Reactions Tetrahedron Letters. VOL 39(NUMBER 39), 7181-7184 NAYLOR, M. A., SWANN, E., EVERETT, S. A., JAFFAR, M., NOLAN, J., ROBERTSON, N., LOCKYER, S. D., PATEL, K. B., DENNIS, M. F. and STRATFORD, M. R. L., 1998. Indolequinone Antitumor Agents: Reductive Activation and Elimination from (5-Methoxy-1-methyl-4,7-dioxoindol-3-yl)methyl Derivatives and Hypoxia-Selective Cytotoxicity in Vitro Journal of Medicinal Chemistry. VOL 41(NUMBER 15), 2720-2731 BEALL, H. D., HUDNOTT, A. R., WINSKI, S., SIEGEL, D., SWANN, E., ROSS, D. and MOODY, C. J., 1998. Indolequinone antitumor agents: relationship between quinone structure and rate of metabolism by recombinant human NQO1 Bioorganic and Medicinal Chemistry Letters. VOL 8(NUMBER 5), 545-548 EVERETT, S.A., HUDNOTT, A.R., MOODY, C.J., NAYLOR, M.A., NOLAN, J., PATEL, K.B., STRATFORD, M.R., SWANN, E. and WARDMAN, P., 1998. Rational design of novel bioreductively-activated prodrugs for the targeted delivery of effector molecules to tumours Annals of Oncology. 9, 111
MOODY, C. J. and PITTS, M. R., 1998. Indium as a Reducing Agent: Selective Reduction of the Heterocyclic Rings in Quinolines, Isoquinolines and Quinoxalines Synlett. NUMBER 9, 1029-1030
MOODY, C. J. and SWANN, E., 1998. N-H Insertion Reactions of Rhodium Carbenoids: A Modified Bischler Indole Synthesis Synlett. NUMBER 2, 135-136
MOODY, C. J. and BAGLEY, M. C., 1998. Studies on Thiopeptide Antibiotics: Synthesis of an Oxazole-Thiazole-Pyridine Fragment related to Promothiocin A Synlett. NUMBER 4, 361-362
MOODY, C. J., MIAH, S., SLAWIN, A. M. Z., MANSFIELD, D. J. and RICHARDS, I. C., 1998. Ligand Effects in the Metal Catalysed Reactions of N-Aryldiazoamides: Ylide Formation vs. Insertion Reactions Tetrahedron. VOL 54(NUMBER 33), 9689-9700 BAGLEY, M. C., BUCK, R. T., HIND, S. L. and MOODY, C. J., 1998. Synthesis of functionalised oxazoles and bis-oxazoles Perkin Transactions 1. NUMBER 3, 591-600
MOODY, C. J. and HUNT, J. C. A., 1998. Addition of Allylmagnesium Bromide to ROPHy/SOPHy Aldoximes: Asymmetric Synthesis of Protected á-Amino Acids Synlett. NUMBER 7, 733-734
MOODY, C. J., MIAH, S., SLAWIN, A. M. Z., MANSFIELD, D. J. and RICHARDS, I. C., 1998. Stereocontrol in the intramolecular Buchner reaction of diazoamides and diazoesters Perkin Transactions 1. NUMBER 24, 4067-4076
MOODY, C. J. and BAGLEY, M. C., 1998. The first synthesis of promothiocin A Chemical Communications. NUMBER 18, 2049-2050 BRIGGS, M. S. J., BRUCE, I., MILLER, J. N., MOODY, C. J., SIMMONDS, A. C. and SWANN, E., 1997. Synthesis of functionalised fluorescent dyes and their coupling to amines and amino acids Perkin Transactions 1. NUMBER 7, 1051-1058
MOODY, C. I., LIGHTFOOT, A. P. and GALLAGHER, P. T., 1997. Addition of Organolithiums to the (R)-O-(1-Phenylbutyl)hydroxylamine (ROPHy) Oxime of Cinnamaldehyde. Asymmetric Synthesis of à-Aminoacids Synlett. NUMBER 6, 659-660
MIAH, S., MOODY, C. J., RICHARDS, I. C. and SLAWIN, A. M. Z., 1997. Synthesis of the marine dibromooxoindoline convolutamydine C Perkin Transactions 1. NUMBER 16, 2405-2412
MOODY, C. J., LIGHTFOOT, A. P. and GALLAGHER, P. T., 1997. Asymmetric Synthesis of 2-Substituted Piperidines. Synthesis of the Alkaloids (-)-Coniine and (+)-Pseudoconhydrine Journal of Organic Chemistry. VOL 62(NUMBER 3), 746-748 MOODY, C. J. and NORTON, C. L., 1997. Synthesis of 1,2-fused indoles by radical cyclisation Perkin Transactions 1. NUMBER 17, 2639-2644
MOODY, C. J., ROFFEY, J. R. A., STEPHENS, M. A. and STRATFORD, I. J., 1997. Synthesis and cytotoxic activity of indolyl thiazoles ANTICANCER DRUGS. VOL 8(NUMBER 5), 489-499 PITT, M. J., EASTON, C. J., MOODY, C. J., FERRANTE, A., POULOS, A. and RATHJEN, D. A., 1997. Synthesis of Polyunsaturated á-Oxa Fatty Acids via Rhodium Mediated Carbenoid Insertion Stuttgart Synthesis. NUMBER 11, 1240-1242 MOODY, C. J. and SWANN, E., 1997. Novel bioreductive anticancer agents based on indolequinones Farmaco. VOL 52(NUMBER 5), 271-279
MOODY, C. J., FERRIS, L., HAIGH, D. and SWANN, E., 1997. A new approach to peptide synthesis Chemical Communications. NUMBER 24, 2391-2392 MOODY, C. J., DOYLE, K. J., ELLIOTT, M. C. and MOWLEM, T. J., 1997. Studies towards the synthesis of diazonamide A. Unexpected formation of a 3,4-bridged indole Perkin Transactions 1. NUMBER 16, 2413-2420
MOODY, C. J. and DOYLE, K. J., 1997. The Synthesis of Oxazoles from Diazocarbonyl Compounds Progress in Heterocyclic Chemistry. VOL 9, 1-16
GALLAGHER, P. T., HUNT, J. C. A., LIGHTFOOT, A. P. and MOODY, C. J., 1997. Chiral oximes in asymmetric synthesis. Part 2. Addition of butyllithium to benzaldehyde O-(1-phenylalkyl)oximes Perkin Transactions 1. NUMBER 17, 2633-2638
FERRIS, L., HAIGH, D. and MOODY, C. J., 1996. New chiral rhodium(II) carboxylates and their use as catalysts in carbenoid transformations Tetrahedron Letters. VOL 37(NUMBER 1), 107-110 FERRIS, L., HAIGH, D. and MOODY, C. J., 1996. N-H Insertion reactions of rhodium carbenoids. Part 2. Preparation of N-substituted amino(phosphoryl)acetates (N-substituted phosphorylglycine esters) Perkin Transactions 1. NUMBER 24, 2885-2888
MIAH, S., SLAWIN, A. M. Z., MOODY, C. J., SHEEHAN, S. M., MARINO, J. P., SEMONES, M. A., PADWA, A. and RICHARDS, I. C., 1996. ligand effects in the rhodium(II) catalysed reactions of diazoamides and diazoimides Tetrahedron. VOL 52(NUMBER 7), 2489-2514 BAGLEY, M. C., BUCK, R. T., HIND, S. L., MOODY, C. J. and SLAWIN, A. M. Z., 1996. A New Route to Functionalised Oxazoles Synlett. NUMBER 9, 825-826 BUCK, R. T., DOYLE, M. P., DRYSDALE, M. J., FERRIS, L., FORBES, D. C., HAIGH, D., MOODY, C. J., PEARSON, N. D. and ZHOU, Q.-L., 1996. Asymmetric rhodium carbenoid insertion into the Si-H bond Tetrahedron Letters. VOL 37(NUMBER 42), 7631-7634 ALLER, E., BUCK, R. T., DRYSDALE, M. J., FERRIS, L., HAIGH, D., MOODY, C. J., PEARSON, N. D. and SANGHERA, J. B., 1996. N-H Insertion reactions of rhodium carbenoids. Part 1. Preparation of à-amino acid and à-aminophosphonic acid derivatives Perkin Transactions 1. NUMBER 24, 2879-2884
MOODY, C. J. and BAGLEY, M. C., 1996. Total Synthesis of (+)-Nostocyclamide Synlett. NUMBER 12, 1171-1172
HARRISON, C.-A., LEINEWEBER, R., MOODY, C. J. and WILLIAMS, J. M. J., 1995. Cyclopenta[b]indoles. Part 1. Synthesis of cyclopenta[b]indoles by formal [3 + 2] addition of indolylmethyl cations to alkenes Perkin Transactions 1. NUMBER 9, 1127
FERRIS, L., HAIGH, D. and MOODY, C. J., 1995. A Simple Route to N-Acylaminophosphonoacetates (N-protected phosphonylglycine esters) Synlett. NUMBER 9, 921
BROWN, D. S., ELLIOTT, M. C., MOODY, C. J. and MOWLEM, T. J., 1995. Preparation of oxonanes and azonanes by oxidative ring expansion: synthesis of obtusan Perkin Transactions 1. NUMBER 9, 1137
COTTERILL, A. S., MOODY, C. J. and ROFFEY, J. R. A., 1995. An improved synthesis of the indolequinone anticancer agent EO9 Tetrahedron. VOL 51(NUMBER 26), 7223 MOODY, C. J. and NORTON, C. L., 1995. Synthesis of 1,2-Fused Indoles by Radical Cyclisation Tetrahedron Letters. VOL 36(NUMBER 49), 9051-9052 GALLAGHER, P.T., LIGHTFOOT, A.P., MOODY, C.J. and SLAWIN, A.M., 1995. Asymmetric Addition of Organometallic Reagents to O-Phenethyl Aldoximes Synlett. 445-446 BROWN, D. S., GALLAGHER, P. T., LIGHTFOOT, A. P. and MOODY, C. J., 1995. Chiral Oximes in Asymmetric Synthesis. Addition of Organometallic Reagents to O-(1-Phenylethyl) Aldoximes Tetrahedron. VOL 51(NUMBER 42), 11473
MOODY, C. J., SWANN, E., HOULBROOK, S. and STEPHENS, M. A., 1995. Synthesis and Biological Activity of Thiazolylindolequinones, Analogues of the Natural Product BE 10988 Journal of Medicinal Chemistry. VOL 38(NUMBER 6), 1039 HARRISON, C.-A., JACKSON, P. M., MOODY, C. J. and WILLIAMS, J. M. J., 1995. Cyclopenta[b]indoles. Part 2. Model studies towards the tremorgenic mycotoxins Perkin Transactions 1. NUMBER 9, 1131
DAWKINS, J. V., MOODY, C. J., PRICE, D. and CASTLE, L., 1995. Isolation and Structural Characterization of Tetrameric Oligomers of Vinyl Chloride Macromolecules. VOL 28(NUMBER 8), 2985 MOODY, C. J., SIE, E.-R. H. B. and KULAGOWSKI, J. J., 1994. Use of diazophosphonates in the synthesis of cyclic ethers. Part 2. Synthesis of the pyranooxepane and oxepanooxepane subunits of marine polyether toxins Perkin Transactions 1. NUMBER 5, 501
MOODY, C.J., O'SULLIVAN, N., STRATFORD, I.J., STEPHENS, M.A., WORKMAN, P., BAILEY, S.M. and LEWIS, A., 1994. Cyclopropamitosenes, Novel Bioreductive Anticancer Agents; Mechanism of Action and Enzymic Reduction Anti-Cancer Drug Design. 5, 367-372
MOODY, C. J. and MORRELL, A. I., 1994. Intramolecular Diels-Alder Reactions of Pyrano[4,3-b]indol-3-ones. Preparation of [c]-Annelated Carbazoles JOURNAL- INDIAN CHEMICAL SOCIETY. VOL 71(NUMBER 6//8), 309
MOODY, C.J., 1994. Synthesis of Carbazole Alkaloids Synlett. 681-688 DOYLE, K. J. and MOODY, C. J., 1994. Synthesis of Oxazolylindolyl Alkaloids via Rhodium Carbenoids Stuttgart Synthesis. NUMBER 10, 1021
COTTERILL, A. S., MOODY, C. J., MORTIMER, R. J. and NORTON, C. L., 1994. Cyclopropamitosenes, Novel Bioreductive Anticancer Agents. Synthesis, Electrochemistry, and Biological Activity of 7-Substituted Cyclopropamitosenes and Related Indolequinones Journal of Medicinal Chemistry. VOL 37(NUMBER 22), 3834 MOODY, C. J., DOYLE, K. J., ELLIOTT, M. C. and MOWLEM, T. J., 1994. Synthesis of heterocyclic natural products: Model studies towards diazonamide A Pure and Applied Chemistry. VOL 66(NUMBER 10/11), 2107 FRAY, E. B., MOODY, C. J. and SHAH, P., 1993. 1,4-Dihydropyrano[3,4-b]indol-3-ones as precursors to indole-2,3-quinodimethanes Tetrahedron. VOL 49(NUMBER 2), 439 HARRISON, C.-A., LEINEWEBER, R., MOODY, C. J. and WILLIAMS, J. M. J., 1993. Synthesis of cyclopent[b]indoles by formal [3+2]-addition of indolylmethyl cations to alkenes Tetrahedron Letters. VOL 34(NUMBER 52), 8527
MOODY, C. J. and SWANN, E., 1993. Synthesis of the topoisomerase II inhibitor BE 10988 Tetrahedron Letters. VOL 34(NUMBER 12), 1987 MOODY, C. J. and SWANN, E., 1993. Synthesis of the naturally occurring indolequinone BE 10988, an inhibitor of topoisomerase II Perkin Transactions 1. NUMBER 21, 2561
ELLIOTT, M. C. and MOODY, C. J., 1993. Preparation of 9-Membered Cyclic Ethers from Phthalans. Synthesis of Obtusan Synlett. NUMBER 12, 909
MOODY, C.J. and DAVIES, M.J., 1992. Recent Developments in the Synthesis of Medium Ring Ethers Studies in Natural Product Chemistry. 10, 201-239
BECK, A.L., MASCAL, M., MOODY, C.J., SLAWIN, A.M., WILLIAMS, D.J. and COATES, W.J., 1992. Synthesis of 3,4-Bridged Indoles by Photocyclisation Reactions. Part 1. Photocyclisation of Haloacetyl Tryptophan Derivatives Journal of the Chemical Society. Perkin Transactions 1. 797-811 MOODY, C.J. and THOMAS, R., 1992. The Pyridoacridine Alkaloids. Advances in Heterocyclic Natural Product Synthesis. 2, 377-400
MASCAL, M., MOODY, C.J., SLAWIN, A.M. and WILLIAMS, D.J., 1992. Synthesis of (-)-indolactam V Journal of the Chemical Society. Perkin Transactions 1. 823-830 COX, G. G., KULAGOWSKI, J. J., MOODY, C. J. and SIE, E.-R. H. B., 1992. Rhodium(II) Trifluoroacetamide; an Excellent Catalyst for Carbenoid O-H Insertion Reactions Synlett. NUMBER 12, 975
MOODY, C.J., RAHIMTOOLA, K.F., PORTER, B. and ROSS, B.C., 1992. Synthesis of the Staurosporine Aglycone Journal of Organic Chemistry. 57, 2105-2114 MOODY, C.J., REES, C.W. and THOMAS, R., 1992. The synthesis of ascididemin Tetrahedron. 48, 3589-3602 HUNT, P.A., MOODY, C.J., SLAWIN, A.M., WILLIAMS, D.J., MYERS, P.L. and SMITH, C., 1992. Beckmann Rearrangements in Bicyclo[2.2.1]heptan-2-one Oximes Journal of the Chemical Society. Perkin Transactions 1. 831-837 COMBER, M.F. and MOODY, C.J., 1992. 2-Chloro-1-methoxymethylindole-3-carboxaldehyde: Introduction of Nucleophiles into the Indole 2-Position and an Approach to the Unusual TrpHis Fragment of Moroidin. Synthesis-Stuttgart. 731-733
MOODY, C.J., SIE, E.R. and KULAGOWSKI, J.J., 1992. The Use of Diazophosphonates in the Synthesis of Cyclic Ethers Tetrahedron. 48, 3991-4004 KENNEDY, M.G., MOODY, C.J., REES, C.W. and THOMAS, R., 1991. Synthesis of a Novel Tetracyclic Acridine. A Sulphoxide-based Route to the 1,2,3,4-Tetrahydrobenzo[b][1,8]phenanthroline Ring System Journal of the Chemical Society. Perkin Transactions 1. 2499-2504 JACKSON, P.M., MOODY, C.J. and MORTIMER, R.J., 1991. Synthesis and electrochemical properties of the naturally occurring free radical scavenger carazostatin Journal of the Chemical Society. Perkin Transactions 1. 2941-2944 MOODY, C. J., REES, C. W. and YOUNG, R. G., 1991. Generation and reactions of N-(à-lithioalkyl)tetrazoles Perkin Transactions 1. NUMBER 2, 323
JONES, G.B., MOODY, C.J., PADWA, A. and KASSIR, J.M., 1991. Inter- and Intra-molecular Reactions of Indol-2-yl Carbenes and Related Species. Preparation of 1,1a,2,8b-Tetrahydroazirino[2',3':3,4]pyrrolo[1,2-a]indoles Journal of the Chemical Society. Perkin Transactions 1. 1721-1727 MOODY, C.J., REES, C.W. and YOUNG, R.G., 1991. Synthesis of 3-phenylpyrazoles from 2-alkenyl-5-phenyltetrazoles Journal of the Chemical Society. Perkin Transactions 1. 329-333 MOODY, C. J., REES, C. W. and YOUNG, R. G., 1991. Synthesis and properties of 4H-imidazoles. Part 2 Perkin Transactions 1. NUMBER 2, 335
MOODY, C.J., REES, C.W. and THOMAS, R., 1990. Synthesis of the Marine Alkaloid Ascididemin. Tetrahedron Letters. 31, 4375-4376 MOODY, C.J. and G. J. WARRELLOW, ., 1990. Vinyl Azides in Heterocyclic Synthesis. Part 10. Synthesis of the Isoindolobenzazepine Alkaloid Lennoxamine. Journal of the Chemical Society. Perkin Transactions 1. 2929-2936 JACKSON, P.M. and MOODY, C.J., 1990. Diels-Alder Reactions of 2,3-Dimethylenepyrrole Analogues; a New Synthesis of Indoles. Journal of the Chemical Society. Perkin Transactions 1. 2156-2158 MOODY, C.J. and RAHIMTOOLA, K.F., 1990. Diels-Alder Reactivity of Pyrano[4,3-b]indol-3-ones, Indole-2,3-Quinodimethane Analogues Journal of the Chemical Society. Perkin Transactions 1. 673-679 MOODY, C.J. and RAHIMTOOLA, K.F., 1990. Synthesis of the Staurosporine Aglycone Journal of the Chemical Society, Chemical Communications. 1667-1668 BECK, A.L., COATES, W.J. and MOODY, C.J., 1990. Preparation of Tetrahydrobenz[cd]indoles from 1-Tetralones. Journal of the Chemical Society. Perkin Transactions 1. 689-693 DAVIES, M.J., MOODY, C.J. and TAYLOR, R.J., 1990. Synthesis and Coupling Reactions of 2-Substituted Oxepanes Synlett. 93-94 JACKSON, P.M. and MOODY, C.J., 1990. Synthesis of the Free Radical Scavenger Carazostatin. Synlett. 521-522