Contact

• workRoom S/D 2125 D flor South Block Respiratory Medicine
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 8231167
• Roya.Babaei-jadidi@nottingham.ac.uk

Selected Publications

• AHMED, MEHREEN, JINKS, NICHOLAS, BABAEI-JADIDI, ROYA, KASHFI, HOSSEIN, CASTELLANOS-URIBE, MARCOS, MAY, SEAN T., MUKHERJEE, ABHIK and NATERI, ABDOLRAHMAN S., 2020. Repurposing Antibacterial AM404 As a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells CANCERS. 12(1),
• LI, NINGNING, BABAEI-JADIDI, ROYA, LORENZI, FEDERICA, SPENCER-DENE, BRADLEY, CLARKE, PHILIP, DOMINGO, ENRIC, TULCHINSKY, EUGENE, VRIES, ROBERT G. J., KERR, DAVID, PAN, YIHANG, HE, YULONG, BATES, DAVID O., TOMLINSON, IAN, CLEVERS, HANS and NATERI, ABDOLRAHMAN S., 2019. An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance ONCOGENESIS. 8,
• TZELEPIS, KONSTANTINOS, DE BRAEKELEER, ETIENNE, ASPRIS, DEMETRIOS, BARBIERI, ISAIA, VIJAYABASKAR, M. S., LIU, WEN-HSIN, GOZDECKA, MALGORZATA, METZAKOPIAN, EMMANOUIL, TOOP, HAMISH D., DUDEK, MONIKA, ROBSON, SAMUEL C., HERMIDA-PRADO, FRANCISCO, YANG, YU HSUEN, BABAEI-JADIDI, ROYA, GARYFALLOS, DIMITRIOS A., PONSTINGL, HANNES, DIAS, JOAO M. L., GALLIPOLI, PAOLO, SEILER, MICHAEL, BUONAMICI, SILVIA, VICK, BINJE, BANNISTER, ANDREW J., RAD, ROLAND, PRINJHA, RAB K., MARIONI, JOHN C., HUNTLY, BRIAN, BATSON, JENNIFER, MORRIS, JONATHAN C., PINA, CRISTINA, BRADLEY, ALLAN, JEREMIAS, IRMELA, BATES, DAVID O., YUSA, KOSUKE, KOUZARIDES, TONY and VASSILIOU, GEORGE S., 2018. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 NATURE COMMUNICATIONS. 9,
• BABAEI-JADIDI, R., LI, N., SAADEDDIN, A., SPENCER-DENE, B., JANDKE, A., MUHAMMAD, B., IBRAHIM, E.E., MURALEEDHARAN, R., ABUZINADAH, M., DAVIS, H., LEWIS, A., WATSON, S., BEHRENS, A., TOMLINSON, I. and NATERI, A.S., 2011. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation Journal of Experimental Medicine. 208(2), 295-312

• View all publications

• AHMED, MEHREEN, JINKS, NICHOLAS, BABAEI-JADIDI, ROYA, KASHFI, HOSSEIN, CASTELLANOS-URIBE, MARCOS, MAY, SEAN T., MUKHERJEE, ABHIK and NATERI, ABDOLRAHMAN S., 2020. Repurposing Antibacterial AM404 As a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells CANCERS. 12(1),
• MILLER, SUZANNE, STEWART, IAIN D., CLEMENTS, DEBBIE, SOOMRO, IRSHAD, BABAEI-JADIDI, ROYA and JOHNSON, SIMON R., 2020. Evolution of lung pathology in lymphangioleiomyomatosis: associations with disease course and treatment response JOURNAL OF PATHOLOGY CLINICAL RESEARCH. 6(3), 215-226
• CLEMENTS, D., BABAEI-JADIDI, R., MILLER, S. and JOHNSON, S. R., 2019. Lymphangioleiomyomatosis (LAM) Nodules Attract and Activate Alveolar Type II Cells AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 199,
• ALI, REEM, ALABDULLAH, MUSLIM, MILIGY, ISLAM, NORMATOVA, MAKHLIYO, BABAEI-JADIDI, ROYA, NATERI, ABDOLRAHMAN S., RAKHA, EMAD A. and MADHUSUDAN, SRINIVASAN, 2019. ATM Regulated PTEN Degradation Is XIAP E3 Ubiquitin Ligase Mediated in p85 alpha Deficient Cancer Cells and Influence Platinum Sensitivity CELLS. 8(10),
• ALMARS, AMANY, CHONDROU, PANAGIOTA S., ONYIDO, EMENIKE K., ALMOZYAN, SHEEMA, SEEDHOUSE, CLAIRE, BABAEI-JADIDI, ROYA and NATERI, ABDOLRAHMAN S., 2019. Increased FLYWCH1 Expression is Negatively Correlated with Wnt/-catenin Target Gene Expression in Acute Myeloid Leukemia Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 20(11),
• LI, NINGNING, BABAEI-JADIDI, ROYA, LORENZI, FEDERICA, SPENCER-DENE, BRADLEY, CLARKE, PHILIP, DOMINGO, ENRIC, TULCHINSKY, EUGENE, VRIES, ROBERT G. J., KERR, DAVID, PAN, YIHANG, HE, YULONG, BATES, DAVID O., TOMLINSON, IAN, CLEVERS, HANS and NATERI, ABDOLRAHMAN S., 2019. An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance ONCOGENESIS. 8,
• MUHAMMAD, BELAL A., ALMOZYAN, SHEEMA, BABAEI-JADIDI, ROYA, ONYIDO, EMENIKE K., SAADEDDIN, ANAS, KASHFI, SEYED HOSSEIN, SPENCER-DENE, BRADLEY, ILYAS, MOHAMMAD, LOURDUSAMY, ANBARASU, BEHRENS, AXEL and NATERI, ABDOLRAHMAN S., 2018. FLYWCH1, a Novel Suppressor of Nuclear beta-Catenin, Regulates Migration and Morphology in Colorectal Cancer MOLECULAR CANCER RESEARCH. 16(12), 1977-1990
• TZELEPIS, KONSTANTINOS, DE BRAEKELEER, ETIENNE, ASPRIS, DEMETRIOS, BARBIERI, ISAIA, VIJAYABASKAR, M. S., LIU, WEN-HSIN, GOZDECKA, MALGORZATA, METZAKOPIAN, EMMANOUIL, TOOP, HAMISH D., DUDEK, MONIKA, ROBSON, SAMUEL C., HERMIDA-PRADO, FRANCISCO, YANG, YU HSUEN, BABAEI-JADIDI, ROYA, GARYFALLOS, DIMITRIOS A., PONSTINGL, HANNES, DIAS, JOAO M. L., GALLIPOLI, PAOLO, SEILER, MICHAEL, BUONAMICI, SILVIA, VICK, BINJE, BANNISTER, ANDREW J., RAD, ROLAND, PRINJHA, RAB K., MARIONI, JOHN C., HUNTLY, BRIAN, BATSON, JENNIFER, MORRIS, JONATHAN C., PINA, CRISTINA, BRADLEY, ALLAN, JEREMIAS, IRMELA, BATES, DAVID O., YUSA, KOSUKE, KOUZARIDES, TONY and VASSILIOU, GEORGE S., 2018. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 NATURE COMMUNICATIONS. 9,
• AHMED M, CHAUDHARI K, BABAEI-JADIDI R, DEKKER LV and NATERI AS, 2017. Emerging Drugs Targeting Epithelial Cancer Stem-like Cells: A Concise Review. Stem cells (Dayton, Ohio). 35(4), 839-850
• BATSON J, TOOP HD, REDONDO C, BABAEI-JADIDI R, CHAIKUAD A, WEARMOUTH SF, GIBBONS B, ALLEN C, TALLANT C, ZHANG J, DU C, HANCOX JC, HAWTREY T, DA ROCHA J, GRIFFITH R, KNAPP S, BATES DO and MORRIS JC, 2017. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease. ACS chemical biology. 12(3), 825-832
• BATSON, JENNIFER, TOOP, HAMISH D., REDONDO, CLARA, BABAEI-JADIDI, ROYA, CHAIKUAD, APIRAT, WEARMOUTH, STEPHEN F., GIBBONS, BRIAN, ALLEN, CLAIRE, TALLANT, CYNTHIA, ZHANG, JINGXUE, DU, CHUNYUN, HANCOX, JULES C., HAWTREY, TOM, DA ROCHA, JOANA, GRIFFITH, RENATE, KNAPP, STEFAN, BATES, DAVID O. and MORRIS, JONATHAN C., 2017. Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease ACS CHEMICAL BIOLOGY. 12(3), 825-832
• FEDERICA LORENZI, ROYA BABAEI-JADIDI, JONATHAN SHEARD, BRADLEY SPENCER-DENE and ABDOLRAHMAN S NATERI, 2016. Fbxw7-associated drug resistance is reversed by induction of terminal differentiation in murine intestinal organoid culture.: Modeling drug treatment response in organoid culture Molecular Therapy — Methods & Clinical Development. 3, 1-9
• NINGNING LI, FEDERICA LORENZI, ELIANA KALAKOUTI, MAKHLIYO NORMATOVA, ROYA BABAEI-JADIDI, IAN TOMLINSON and ABDOLRAHMAN S. NATERI, 2015. FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15. Oncotarget. 6(11), 9240-56.
• MAVROU, A., BRAKSPEAR, K., HAMDOLLAH-ZADEH, M., DAMODARAN, G., BABAEI-JADIDI, R., OXLEY, J., GILLATT, D. A., LADOMERY, M. R., HARPER, S. J., BATES, D. O. and OLTEAN, S., 2015. Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer ONCOGENE. 34(33), 4311-4319
• BATSON, JENNIFER, TROOP, HAMISH, ROWLINSON, JONATHAN, ALLEN, CLAIRE, BABAEI-JADIDI, ROYA, ZHANG, JINGXUE, WEARMOUTH, STEPHEN, KNAPP, STEFAN, MORRIS, JONATHAN and BATES, DAVID, 2015. Development of SRPK1 inhibitors as novel anti-angiogenic therapeutics for exudative age-related macular degeneration (AMD) INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 56(7),
• ROWLINSON, J., BATSON, J., TOOP, H., ALLEN, C., GIBBONS, B., BABAEI-JADIDI, R., ZHANG, J., WEARMOUTH, S., KNAPP, S., MORRIS, J. and BATES, D., 2015. Novel SRPK1 inhibitors specifically target alternative splicing in human primary retinal epithelial cells ACTA OPHTHALMOLOGICA. 93,
• LI, NINGNING, BABAEI-JADIDI, ROYA, LORENZI, FEDERICA and NATERI, ABDOLRAHMAN S., 2015. FBXW7 ORCHESTRATES A FAILSAFE PROGRAM AGAINST COLORECTAL CANCER PROGRESSION ANTICANCER RESEARCH. 35(7), 4316-4316
• IBRAHIM, ELSAYED E, BABAEI-JADIDI, ROYA and NATERI, ABDOLRAHMAN S, 2013. The streptavidin/biotinylated DNA/protein bound complex protocol for determining the association of c-JUN protein with NANOG promoter. Current protocols in stem cell biology. Chapter 1, Unit 1B.10
• IBRAHIM, E.E., BABAEI-JADIDI, R., SAADEDDIN, A., SPENCER-DENE, B., HOSSAINI, S., ABUZINADAH, M., LI, N., FADHIL, W., ILYAS, M., BONNET, D. and NATERI, A.S., 2012. Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms Stem Cells. 30(10), 2076-2087
• BABAEI-JADIDI, R., LI, N., SAADEDDIN, A., SPENCER-DENE, B., JANDKE, A., MUHAMMAD, B., IBRAHIM, E.E., MURALEEDHARAN, R., ABUZINADAH, M., DAVIS, H., LEWIS, A., WATSON, S., BEHRENS, A., TOMLINSON, I. and NATERI, A.S., 2011. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation Journal of Experimental Medicine. 208(2), 295-312
• KARACHALIAS N, BABAEI-JADIDI R, RABBANI N and THORNALLEY PJ, 2010. Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes. Diabetologia. 53(7), 1506-16
• SAADEDDIN, A., BABAEI-JADIDI, R., SPENCER-DENE, B. and NATERI, A.S., 2009. The links between transcription, β-catenin/JNK signaling, and carcinogenesis Molecular Cancer Research. 7(8), 1189-1196
• XUE M, QIAN Q, ADAIKALAKOTESWARI A, RABBANI N, BABAEI-JADIDI R and THORNALLEY PJ, 2008. Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes. 57(10), 2809-17
• THORNALLEY PJ, BABAEI-JADIDI R, AL ALI H, RABBANI N, ANTONYSUNIL A, LARKIN J, AHMED A, RAYMAN G and BODMER CW, 2007. High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease. Diabetologia. 50(10), 2164-70
• AHMED N, BABAEI-JADIDI R, HOWELL SK, THORNALLEY PJ and BEISSWENGER PJ, 2005. Glycated and oxidized protein degradation products are indicators of fasting and postprandial hyperglycemia in diabetes. Diabetes care. 28(10), 2465-71
• KARACHALIAS N, BABAEI-JADIDI R, KUPICH C, AHMED N and THORNALLEY PJ, 2005. High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats. Annals of the New York Academy of Sciences. 1043, 777-83
• AHMED N, BABAEI-JADIDI R, HOWELL SK, BEISSWENGER PJ and THORNALLEY PJ, 2005. Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes. Diabetologia. 48(8), 1590-603
• AHMED N, MIRSHEKAR-SYAHKAL B, KENNISH L, KARACHALIAS N, BABAEI-JADIDI R and THORNALLEY PJ, 2005. Assay of advanced glycation endproducts in selected beverages and food by liquid chromatography with tandem mass spectrometric detection. Molecular nutrition & food research. 49(7), 691-9
• AGALOU S, AHMED N, BABAEI-JADIDI R, DAWNAY A and THORNALLEY PJ, 2005. Profound mishandling of protein glycation degradation products in uremia and dialysis. Journal of the American Society of Nephrology : JASN. 16(5), 1471-85
• BABAEI-JADIDI R, KARACHALIAS N, KUPICH C, AHMED N and THORNALLEY PJ, 2004. High-dose thiamine therapy counters dyslipidaemia in streptozotocin-induced diabetic rats. Diabetologia. 47(12), 2235-46
• REID, F., LOBO, D. N., WILLIAMS, R. N., ROWLANDS, B. J. and ALLISON, S. P., 2003. (Ab)normal saline and physiological Hartmann's solution: a randomized double-blind crossover study: Clinical science Clinical science. 104(1), 17-24
• AHMED N, BATTAH S, KARACHALIAS N, BABAEI-JADIDI R, HORÁNYI M, BARÓTI K, HOLLAN S and THORNALLEY PJ, 2003. Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency. Biochimica et biophysica acta. 1639(2), 121-32
• THORNALLEY PJ, BATTAH S, AHMED N, KARACHALIAS N, AGALOU S, BABAEI-JADIDI R and DAWNAY A, 2003. Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry. The Biochemical journal. 375(Pt 3), 581-92
• BABAEI-JADIDI R, KARACHALIAS N, AHMED N, BATTAH S and THORNALLEY PJ, 2003. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes. 52(8), 2110-20