Publications 2021
Abdelrazig S, Ortori CA, Doherty M, Valdes AM, Chapman V, Barrett DA. Metabolic signatures of osteoarthritis in urine using liquid chromatography-high resolution tandem mass spectrometry. Metabolomics. 2021 Mar 3;17(3):29. doi: 10.1007/s11306-021-01778-3. PMID: 33655418; PMCID: PMC7925472.
Akin-Akinyosoye K, James RJE, McWilliams DF, Millar B, das Nair R, Ferguson E, Walsh DA. The Central Aspects of Pain in the Knee (CAP-Knee) questionnaire; a mixed-methods study of a self-report instrument for assessing central mechanisms in people with knee pain. Osteoarthritis Cartilage. 2021 Jun;29(6):802-814. doi: 10.1016/j.joca.2021.02.562. Epub 2021 Feb 20. PMID: 33621705; PMCID: PMC8177001.
Aso K, Shahtaheri SM, McWilliams DF, Walsh DA. Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative. Arthritis Res Ther. 2021 Jan 19;23(1):35. doi: 10.1186/s13075-021-02422-0. PMID: 33468243; PMCID: PMC7816469.
Ayub S, Kaur J, Hui M, Espahbodi S, Hall M, Doherty M, Zhang W. Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis-a systematic review and meta-analysis of randomized controlled trials and observational studies. Rheumatology (Oxford). 2021 Apr 6;60(4):1629-1639. doi: 10.1093/rheumatology/keaa808. PMID: 33432345.
Barker KL, Room J, Knight R CORKA Trial group, et alHome-based rehabilitation programme compared with traditional physiotherapy for patients at risk of poor outcome after knee arthroplasty: the CORKA randomised controlled trialBMJ Open 2021;11:e052598. doi: 10.1136/bmjopen-2021-052598
Bauer M, Buckley MG, Bast T. Individual differences in theta-band oscillations in a spatial memory network revealed by electroencephalography predict rapid place learning. Brain and Neuroscience Advances. 2021;5. doi:10.1177/23982128211002725
Bestwick-Stevenson, T., Wyatt, L.A., Palmer, D. et al. Incidence and risk factors for poor ankle functional recovery, and the development and progression of posttraumatic ankle osteoarthritis after significant ankle ligament injury (SALI): the SALI cohort study protocol. BMC Musculoskelet Disord 22, 362 (2021). https://doi.org/10.1186/s12891-021-04230-8
Bonifazi A, Battiti FO, Sanchez J, Zaidi SA, Bow E, Makarova M, Cao J, Shaik AB, Sulima A, Rice KC, Katritch V, Canals M, Lane JR, Newman AH. Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management. J Med Chem. 2021 Jun 10;64(11):7778-7808. doi: 10.1021/acs.jmedchem.1c00611. Epub 2021 May 20. PMID: 34011153; PMCID: PMC9308496.
Cai K., Fuller A., Zhang Y., Hensey O., Grossberg D. Christensen R., Shea B., Singh J.A., McCarthy G.M., Rosenthal A.K., Filippou G., Taylor W.J., Diaz-Torne C., Stamp L.K., Edwards N.L., Pascart T., Becce F., Nielsen S.M., Tugwell P., Beaton D., Abishek A., Tedeschi S.K., Dalbeth N., 2021, Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group. Semin Arthritis Rheum; 51(4):946-950. doi: 10.1016/j.semarthrit.2021.04.019
Cuitavi J, Hipólito L, Canals M. The Life Cycle of the Mu-Opioid Receptor. Trends Biochem Sci. 2021 Apr;46(4):315-328. doi: 10.1016/j.tibs.2020.10.002. Epub 2020 Oct 27. PMID: 33127216.
Feng W, Qin C, Cipolla E, Lee JB, Zgair A, Chu Y, Ortori CA, Stocks MJ, Constantinescu CS, Barrett DA, Fischer PM, Gershkovich P. Inclusion of Medium-Chain Triglyceride in Lipid-Based Formulation of Cannabidiol Facilitates Micellar Solubilization In Vitro, but In Vivo Performance Remains Superior with Pure Sesame Oil Vehicle. Pharmaceutics. 2021 Aug 27;13(9):1349. doi: 10.3390/pharmaceutics13091349. PMID: 34575426; PMCID: PMC8472830.
Feng, Wanshan et al. “Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol.” European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V (2021): n. pag.
Fuller, A., Cai, K., Diaz-Torne, C., Filippou, G., Pascart, T., Hensey, O., Grossberg, D., Christensen, R., Shea, B., Singh, J. A., Tedeschi, S. K., Dalbeth, N., & Abhishek, A. (2021). Outcome domains reported by patients, caregivers, healthcare professionals and stakeholders for calcium pyrophosphate deposition (CPPD): A content analysis based on semi-structured qualitative interviews from the OMERACT CPPD working group. Seminars in Arthritis and Rheumatism, 51(3), 650-654. https://doi.org/10.1016/j.semarthrit.2020.09.021
Hodkinson DJ, Bungert A, Bowtell R, Jackson SR, Jung J. Operculo-insular and anterior cingulate plasticity induced by transcranial magnetic stimulation in the human motor cortex: a dynamic casual modeling study. J Neurophysiol. 2021 Apr 1;125(4):1180-1190. doi: 10.1152/jn.00670.2020. Epub 2021 Feb 24. PMID: 33625934.
Hill R, Canals M. Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology. Pharmacol Ther. 2022 Feb;230:107961. doi: 10.1016/j.pharmthera.2021.107961. Epub 2021 Jul 10. PMID: 34256067; PMCID: PMC7612340.
Hochberg MC, Carrino JA, Schnitzer TJ, Guermazi A, Walsh DA, White A, Nakajo S, Fountaine RJ, Hickman A, Pixton G, Viktrup L, Brown MT, West CR, Verburg KM. Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial. Arthritis Rheumatol. 2021 Jul;73(7):1167-1177. doi: 10.1002/art.41674. Epub 2021 Jun 7. PMID: 33538113.
Ifesemen OS, McWilliams DF, Ferguson E, Wakefield R, Akin-Akinyosoye K, Wilson D, Platts D, Ledbury S, Walsh DA. Central Aspects of Pain in Rheumatoid Arthritis (CAP-RA): protocol for a prospective observational study. BMC Rheumatol. 2021 Jun 24;5(1):23. doi: 10.1186/s41927-021-00187-2. PMID: 34162435; PMCID: PMC8223274.
Jiang T, Yang T, Zhang W, Doherty M, Zhang Y, Wei J, Sarmanova A, Hall M, Yang Z, Li J, Fernandes GS, Obotiba AD, Gohir SA, Courtney P, Zeng C, Lei G. Prevalence of ultrasound-detected knee synovial abnormalities in a middle-aged and older general population-the Xiangya Osteoarthritis Study. Arthritis Res Ther. 2021 Jun 2;23(1):156. doi: 10.1186/s13075-021-02539-2. PMID: 34078472; PMCID: PMC8170794.
Levy N, Quinlan J, El-Boghdadly K, Fawcett WJ, Agarwal V, Bastable RB, Cox FJ, de Boer HD, Dowdy SC, Hattingh K, Knaggs RD, Mariano ER, Pelosi P, Scott MJ, Lobo DN, Macintyre PE. An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients. Anaesthesia. 2021 Apr;76(4):520-536. doi: 10.1111/anae.15262. Epub 2020 Oct 7. PMID: 33027841.
Li Y, Ma J, Lu G, Dou Z, Knaggs R, Xia J, Zhao S, Dong S, Yang L. Hydromorphone for cancer pain. Cochrane Database Syst Rev. 2021 Aug 5;8(8):CD011108. doi: 10.1002/14651858.CD011108.pub3. PMID: 34350974; PMCID: PMC8406835.
McWilliams DF, Thankaraj D, Jones-Diette J, Morgan R, Ifesemen OS, Shenker NG, Walsh DA. The efficacy of systemic glucocorticosteroids for pain in rheumatoid arthritis: a systematic literature review and meta-analysis. Rheumatology (Oxford). 2021 Dec 24;61(1):76-89. doi: 10.1093/rheumatology/keab503. PMID: 34213524; PMCID: PMC8742830.
Morgan CL, Jenkins-Jones S, Knaggs R, Currie C, Conway P, Poole CD, Berni E. Characterization and Associated Costs of Constipation Relating to Exposure to Strong Opioids in England: An Observational Study. Clin Ther. 2021 Jun;43(6):968-989. doi: 10.1016/j.clinthera.2021.03.021. Epub 2021 Apr 27. PMID: 33931241.
Nomikos PA, Hall M, Fuller A, Millar B, Ogollah R, Valdes A, Doherty M, Walsh DA, das Nair R, Abhishek A. Fidelity assessment of nurse-led non-pharmacological package of care for knee pain in the package development phase of a feasibility randomised controlled trial based in secondary care: a mixed methods study. BMJ Open. 2021 Jul 29;11(7):e045242. doi: 10.1136/bmjopen-2020-045242. PMID: 34326044; PMCID: PMC8323379.
Parekh SM, Fernandes GS, Moses JP, Fuller CW, Scammell BE, Batt ME, Zhang W, Doherty M. Risk Factors for Knee Osteoarthritis in Retired Professional Footballers: A Cross-Sectional Study. Clin J Sport Med. 2021 May 1;31(3):281-288. doi: 10.1097/JSM.0000000000000742. PMID: 31157625; PMCID: PMC8061337.
Peach EJ, Pearce FA, Gibson J, Cooper AJ, Chen LC, Knaggs RD. Opioids and the Risk of Fracture: A Self-Controlled Case Series Study in the Clinical Practice Research Datalink. Am J Epidemiol. 2021 Jul 1;190(7):1324-1331. doi: 10.1093/aje/kwab042. PMID: 33604606; PMCID: PMC8245882.
Perry TA, Yang X, van Santen J, Arden NK, Kluzek S. Quantitative and semi-quantitative assessment of synovitis on MRI and the relationship with symptoms in symptomatic knee osteoarthritis. Rheumatology (Oxford). 2021 Apr 6;60(4):1763-1773. doi: 10.1093/rheumatology/keaa619. PMID: 33097941; PMCID: PMC8023988.
Persson MSM, Stocks J, Sarmanova A, Fernandes G, Walsh DA, Doherty M, Zhang W. Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials. Rheumatology (Oxford). 2021 May 14;60(5):2231-2237. doi: 10.1093/rheumatology/keaa561. PMID: 33197270.
Petersen KK, Vaegter HB, Stubhaug A, Wolff A, Scammell BE, Arendt-Nielsen L, Larsen DB. The predictive value of quantitative sensory testing: a systematic review on chronic postoperative pain and the analgesic effect of pharmacological therapies in patients with chronic pain. Pain. 2021 Jan;162(1):31-44. doi: 10.1097/j.pain.0000000000002019. PMID: 32701654.
Phelps CE, Lumb BM, Donaldson LF, Robinson ES. The partial saphenous nerve injury model of pain impairs reward-related learning but not reward sensitivity or motivation. Pain. 2021 Mar 1;162(3):956-966. doi: 10.1097/j.pain.0000000000002177. PMID: 33591111.
Srivastava D., Hill S., Carty S., Rockett M., Bastable R., Knaggs R., Lambert D., Levy N., Hughes J., Wilkinson P., 2021, Surgery and opioids: evidence-based expert consensus guidelines on the perioperative use of opioids in the United Kingdom. British journal of anaesthesia, 126(6), 1208–1216. https://doi.org/10.1016/j.bja.2021.02.030
Swain S, Coupland C, Mallen C, Kuo CF, Sarmanova A, Bierma-Zeinstra SMA, Englund M, Prieto-Alhambra D, Doherty M, Zhang W. Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting. Rheumatology (Oxford). 2021 Sep 1;60(9):4327-4339. doi: 10.1093/rheumatology/keab067. PMID: 33506862; PMCID: PMC8410005.
Vijay A., Kouraki A., Gohir S., Turnbull J., Kelly A., Chapman V., Barrett D.A., Bulsiewicz W.J., Valdes A.M., 2021, Gut Microbes, The anti-inflammatory effect of bacterial short chain fatty acids is partially mediated by endocannabinoids, 13(1):1997559. doi: 10.1080/19490976.2021.1997559.
Walsh DA. Nociplastic pain: helping to explain disconnect between pain and pathology. Pain. 2021 Nov 1;162(11):2627-2628. doi: 10.1097/j.pain.0000000000002323. PMID: 34652319.
Zeng C, Zhang W, Doherty M, Persson MSM, Mallen C, Swain S, Li X, Wei J, Lei G, Zhang Y. Initial analgesic prescriptions for osteoarthritis in the United Kingdom, 2000-2016. Rheumatology (Oxford). 2021 Jan 5;60(1):147-159. doi: 10.1093/rheumatology/keaa244. PMID: 32594175.
Xiong Y., Zeng C., Doherty M., Persson M., Wei J., van Middelkoop M., Lei G., Zhang W., 2021, Identifying predictors of response to oral non-steroidal anti-inflammatory drugs and paracetamol in osteoarthritis: a hypothesis-driven protocol for an OA Trial Bank individual participant data meta-analysis. BMJ open, 11(8), e048652. https://doi.org/10.1136/bmjopen-2021-048652
Yang X., Thudium C. S., Bay-Jensen A. C., Karsdal M. A., van Santen J., Arden N. K., Perry T. A., Kluzek S., 2021, Association between Markers of Synovial Inflammation, Matrix Turnover and Symptoms in Knee Osteoarthritis: A Cross-Sectional Study. Cells, 10(7), 1826. https://doi.org/10.3390/cells10071826