CKD in primary care

A major publication in PLOS Medicine this month (September 2016) has highlighted the impact of results from the Renal Risk in Derby Study. (See press release.)

The RRID study is led by Maarten Taal and in the paper, Adam Shardlow and colleagues report on the progression of chronic kidney disease over 5 years among patients in primary care. Interestingly, remission of CKD stage 3A was described in detail for the first time, occurring in almost 20% of patients. These data emphasise that the management of chronic kidney disease by family doctors should focus on identifying the minority of people who are at high risk of adverse outcomes for more intensive treatment and referral, whilst people at low risk should also be identified so that they can be reassured and spared unnecessary treatment or referral. Conclusions also include the need for an internationally agreed definition for “remission” of chronic kidney disease. 

This publication follows another article from the CKRI group also published in PLOS Medicine this month: International Criteria for Acute Kidney Injury: Advantages and Remaining Challenges.

Article links: 

 Interplay between Diagnostic Criteria and Prognostic Accuracy in Chronic Kidney Disease

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002128

 Accompanying editorial

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002129

International Criteria for Acute Kidney Injury: Advantages and Remaining Challenges

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002122