Helen Barr

Contact

• workRoom B19 Clinical Sciences Building
  Nottingham City Hospital
  Hucknall Road
  Nottingham
  NG5 1PB
  UK
• work0115 823 1326
• Helen.Barr@nottingham.ac.uk

Research Summary

The main focus of my research is in respiratory infection, particularly cystic fibrosis. Areas of specific interest are quorum sensing, biofilm diversity and host response to infection. I also have… read more

Selected Publications

• BARR, H.L., BRITTON, J., SMYTH, A.R. and FOGARTY, A.W., 2011. Association between socioeconomic status, sex, and age at death from cystic fibrosis in England and Wales (1959 to 2008): cross sectional study BMJ. 343(7821), d4662
• BARR HL, MACFARLANE JT, MACGREGOR O, FOXWELL R, BUSWELL V and LIM WS, 2008. Ethical Planning For An Influenza Pandemic. Clinical Medicine (London, England). 8(1), 49-52

• View all publications

Current Research

The main focus of my research is in respiratory infection, particularly cystic fibrosis. Areas of specific interest are quorum sensing, biofilm diversity and host response to infection. I also have interests in lung cancer and respiratory epidemiology.

We have recently completed recruitment for a £850, 000 MRC funded project, exploring the clinical potential of quorum sensing modules as novel biomarkers for pseudomonas aeriginosa infection in cystic fibrosis.

• BARR HL, HALLIDAY N, BARRETT DA, WILLIAMS P, FORRESTER DL, PECKHAM D, WILLIAMS K, SMYTH AR, HONEYBOURNE D, L WHITEHOUSE J, NASH EF, DEWAR J, CLAYTON A, KNOX AJ, CÁMARA M and FOGARTY AW, 2016. Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: A longitudinal study. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 16(2), 230-238
• DARCH, SOPHIE E., MCNALLY, ALAN, HARRISON, FREYA, CORANDER, JUKKA, BARR, HELEN L., PASZKIEWICZ, KONRAD, HOLDEN, STEPHEN, FOGARTY, ANDREW, CRUSZ, SHANIKA A. and DIGGLE, STEPHEN P., 2015. Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection SCIENTIFIC REPORTS. 5,
• SINGH, SONALI, BARR, HELEN, LIU, YI-CHIA, ROBINS, ADRIAN, HEEB, STEPHAN, WILLIAMS, PAUL, FOGARTY, ANDREW, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2015. Granulocyte-Macrophage Colony Stimulatory Factor Enhances the Pro-Inflammatory Response of Interferon-gamma-Treated Macrophages to Pseudomonas aeruginosa Infection PLOS ONE. 10(2),
• BARR, H. L., HALLIDAY, N., CAMARA, M., BARRETT, D. A., WILLIAMS, P., FORRESTER, D. L., SIMMS, R., SMYTH, A. R., HONEYBOURNE, D., WHITEHOUSE, J. L., NASH, E. F., DEWAR, J., CLAYTON, A., KNOX, A. J. and FOGARTY, A. W., 2015. Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis: Eur Respir J Eur Respir J.
• FORRESTER DL, KNOX AJ, SMYTH AR, BARR HL, SIMMS R, PACEY SJ, PAVORD ID, HONEYBOURNE D, DEWAR J, CLAYTON A and FOGARTY AW, 2015. Glutamine supplementation in cystic fibrosis: A randomized placebo-controlled trial. Pediatric pulmonology. 51(3), 253-7
• BARR, H. L., CAMARA, M., BARRETT, D., WILLIAMS, P., FORRESTER, D., HALLIDAY, N., SMYTH, A., HONEYBOURNE, D., WHITEHOUSE, J., NASH, E. F., DEWAR, J., CLAYTON, A., MCKEEVER, T., KNOX, A. and FOGARTY, A., 2014. FACTORS PREDICTING A SHORTER TIME TO NEXT PULMONARY EXACERBATION IN ADULTS WITH CYSTIC FIBROSIS PEDIATRIC PULMONOLOGY. 49, 326-327
• BARR, H.L., BRITTON, J., SMYTH, A.R. and FOGARTY, A.W., 2011. Association between socioeconomic status, sex, and age at death from cystic fibrosis in England and Wales (1959 to 2008): cross sectional study BMJ. 343(7821), d4662
• BARR HL, MACFARLANE JT, MACGREGOR O, FOXWELL R, BUSWELL V and LIM WS, 2008. Ethical Planning For An Influenza Pandemic. Clinical Medicine (London, England). 8(1), 49-52