School of Pharmacy

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Giuseppe Mantovani

Associate Professor in Biomedical Polymers, Director of PGR Studies, Faculty of Science

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Biography

I gained my degree in Industrial Chemistry at the University of Bologna (Italy) in 1998. This included a 12 months research project in organic synthetic methodologies working at the sulphur-mediated total synthesis of enantiopure conduritols starting from reduced sugars, in Prof. V. Cere's group.In Nov 2002 I was awarded my PhD in Chemistry (Corso di Perfezionamento in Scienze degli Idrocarburi) from the Scuola Normale Superiore of Pisa (Italy) working on the design and synthesis of novel transition-metal catalysts based on iminopyridine ligands for the olygomerisation of ethylene to alpha-olefins (research sponsored by ENI spa) in Dr. C. Bianchini's group at the ICCOM-CNR institute in Florence.Shortly afterwards I joined the group of Prof. D. M. Haddleton at the University of Warwick as a post-doctoral research assistant. In the 2003-2005 period I held a Marie Curie Post-doctoral Fellowship awarded by the European Commission.In Warwick I've been involved in a number of different projects mainly focused on the use of controlled radical polymerisation techniques (mainly transition metal-mediated living radical polymerisation, TMM-LRP, often termed ATRP) for:

  • Design and synthesis of novel protein biohybrid materials obtained by site-specific conjugation of precision alpha-functional polymers to appropriate (poly)peptides.
  • Design and synthesis of well-defined functional glycopolymers and study of their ability of recognising specific protein receptors (lectins)
  • Grafting of functional macromolecules to surfaces (glass, cellulose, crosslinked polystyrene beads) via "grafting to" and "grafting from" approaches.
  • 4) Combination of Cu(I)-catalysed Living Radical Polymerisation (LRP) with other synthetic techniques (i.e. "click" chemistry).

In Jan 2009 I was appointed Lecturer in Lecturer in Biologics Delivery in the School of Pharmacy at Nottingham.

Past Research (Keywords)Gycomic and Bioresponsive Materials Science, Macromolecular and Bioconjugation Chemistry, Tandem Organometallic Catalysis, Total Synthesis.

Research Summary

The development of materials able to inform, interrogate, and instruct biological systems is emerging as one of the fastest growing and exciting fields in science. These information-rich materials… read more

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

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