Identifying and targeting modifiable inflammatory factors underlying higher risk of frailty in individuals experiencing deprivation
This projects aims to develop interventions targeting inflammatory mechanisms of ageing, intensified by social deprivation, to prevent premature frailty.
Duration: 18 months
Funder: MRC
Partners:
Adam Gordon, Ana Valdes, Benjamin Ollivere - School of Medicine
CHILL investigators:
Professor Stephen Timmons
Research summary
Background:
The overarching aim of this project is to develop interventions that address the inflammatory mechanisms of ageing, which are exacerbated by social deprivation and contribute to premature frailty. Our interdisciplinary approach integrates microbiome and proteomic data from various dietary supplementation and physiotherapy studies and assesses the feasibility and acceptability among socially deprived groups through qualitative research. This research has the potential to improve the quality of life for older adults and, mitigate premature ageing, frailty, and eventually fractures and death.
