UK researchers have, for the first time, used a chemical to prevent the death of brain tissue in a neurodegenerative disease. Pharmacy researchers at Nottingham have been collaborating with Prof Mallucci at Leicester MRC Toxicology Unit, who led the research.
The paper, which received substantial national and international media attention, can be seen here:
Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
Julie A. Moreno et al.
Sci Transl Med 5, 206ra138 (2013)
To see some of the media attention, please follow the links below:
http://www.bbc.co.uk/news/health-24462699
http://www.bbc.co.uk/news/health-24478942
Nearly every report contains this quote from Professor Roger Morris, at King's College London:
"This finding, I suspect, will be judged by history as a turning point in the search for medicines to control and prevent Alzheimer's disease".
Posted on Tuesday 15th October 2013