School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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BYRNE, C., MCEWAN, P.A., EMSLEY, J., FISCHER, P.M. and CHAN, W.C., 2011. End-stapled homo and hetero collagen triple helices: a click chemistry approach Chemical Communications. 47(9), 2589-2591

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HALL, GARETH, BRADSHAW, TRACEY D, LAUGHTON, CHARLES A, STEVENS, MALCOLM F and EMSLEY, JONAS, 2011. Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464. Protein science : a publication of the Protein Society. 20(1), 210-5

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EDWARDS, J., MALAURIE, E., KONDRASHOV, A., LONG, J., DE MOOR, C.H., SEARLE, M.S. and EMSLEY, J., 2011. Sequence determinants for the tandem recognition of UGU and CUG rich RNA elements by the two N-terminal RRMs of CELF1 Nucleic Acids Research. 39(19), 8638-8650

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MCEWAN, P.A., YANG, W., CARR, K.H., MO, X., ZHENG, X., LI, R. and EMSLEY, J., 2011. Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera Blood. 118(19), 5292-5301

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KAUR, I., SCHRAMM, G., EVERTS, B., SCHOLZEN, T., KINDLE, K.B., BEETZ, C., MONTIEL-DUARTE, C., BLINDOW, S., JONES, A.T., HAAS, H., STOLNIK, S., HEERY, D.M. and FALCONE, F.H., 2011. Interleukin-4 inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake Infection and Immunity. 79(4), 1779-1788

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WANG, S., MEADES, C., WOOD G., O'BOYLE, J., MCINNES, C. and FISCHER, P.M., 2011. Pyrimidine compounds US07897605 03/01/2011 00:00:00

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LIU, XIANGRUI, SHI, SHENHUA, LAM, FRANKIE, PEPPER, CHRIS, FISCHER, PETER M and WANG, SHUDONG, 2011. CDKI-71, a novel CDK9 inhibitor, is preferentially cytotoxic to cancer cells compared to flavopiridol. International journal of cancer. Journal international du cancer.

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MOHAMMED, M.Z., VYJAYANTI, V.N., LAUGHTON, C.A., DEKKER, L.V., FISCHER, P.M., WILSON, D.M., ABBOTTS, R., SHAH, S., PATEL, P.M., HICKSON, I.D. and MADHUSUDAN, S., 2011. Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines British Journal of Cancer. 104(4), 653-663

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REDDY, T.R.K., LI, C., GUO, X., MYRVANG, H.K., FISCHER, P.M. and DEKKER, L.V., 2011. Design, synthesis, and SAR exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2–S100A10 protein interaction Journal of Medicinal Chemistry. 54(7), 2080-2094

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WILSON SC, ATRASH B, BARLOW C, ECCLES S, FISCHER PM, HAYES A, KELLAND L, JACKSON W, JARMAN M, MIRZA A, MORENO J, NUTLEY BP, RAYNAUD FI, SHELDRAKE P, WALTON M, WESTWOOD R, WHITTAKER S, WORKMAN P and MCDONALD E, 2011. Design, Synthesis And Biological Evaluation Of 6-Pyridylmethylaminopurines As Cdk Inhibitors. Bioorganic & Medicinal Chemistry. 19(22), 6949-65

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JADHAV GP, CHHABRA SR, TELFORD G, HOOI DS, RIGHETTI K, WILLIAMS P, KELLAM B, PRITCHARD DI and FISCHER PM, 2011. Immunosuppressive but non-LasR-inducing analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone. Journal of Medicinal Chemistry. 54(9), 3348-3359

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REDDY, T.R.K., LI, C., FISCHER, P.M. and DEKKER, L.V., 2011. Preparation of pyrrole derivatives as S100 protein binding interaction inhibitors for treatment of cancer and other diseases WO2011092505 A1 WO2011-GB50137 GB2010-1596 WO 2011092505 08/04/2011 00:00:00

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MITTAL, S., ASLAM, A., DOIDGE, R., MEDICA, R. and WINKLER, G.S., 2011. The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence Molecular Biology of the Cell. 22(6), 748-758

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BEARON, RN, HAZEL, AL and THORN, GJ, 2011. The spatial distribution of gyrotactic swimming micro-organisms in laminar flow fields Journal of Fluid Mechanics. 680, 602-635

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ASHRAF, S., MAPP, P.I. and WALSH, D.A., 2011. Contributions of angiogenesis to inflammation, joint damage and pain in a rat model of osteoarthritis Arthritis and Rheumatism. 63(9), 2700-2710
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School of Pharmacy

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