Staff listing for the Molecular Therapeutics and Formulation Division
Cynthia Bosquillon
Assistant Professor in Drug Delivery, Faculty of Science
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Biography
I graduated as a pharmacist from the Université catholique de Louvain, Belgium in 1998 and then pursued post-graduate studies under the co-supervision of Profs. Rita Vanbever and Véronique Préat. I gained my PhD in September 2003 and in 2004, I moved to London to work on a post-doctoral project directed by Dr.Ben Forbes (King's College London) and Dr.Nicola Clear (Pfizer R&D). In 2005, I was awarded a University of London Maplethorpe fellowship, which gave me, in addition to a valuable teaching experience, the opportunity to develop my own research area and supervise both undergraduate and postgraduate research students at King's. I was appointed to a lectureship in Drug Delivery at Nottingham in 2007.
My research is mainly focused on drug inhalation, of which I've explored different aspects, from the formulation and characterisation of dry powders for systemic delivery of therapeutic proteins to the development and validation of in vitro and ex vivo models of the lungs as tools to predict pulmonary drug absorption in vivo.
Expertise Summary
pulmonary drug delivery; biopharmaceutics; in vitro models; drug transport mechanisms; drug transporters; pro-drugs
Research Summary
My current research interests include:
- the use of respiratory epithelial cell culture models to investigate drug disposition in the lungs, including the impact of drug transporters and lung pathological conditions.
- the development of in vitro systems to study the interactions between drugs/drug particles and airway mucus.
- the development of strategies based on drug design or formulation to optimise drug retention in the lungs.