This Vasculitis UK project assessed strength of response to Covid-19 vaccination among people with vasculitis and rare autoimmune diseases in Nottingham
This was a University of Nottingham collaboration between the RECORDER team and Prof Lucy Fairclough, immunology scientist in the School of Life Sciences
Background
People with vasculitis and other rare autoimmune rheumatic diseases are often treated with immunosuppression, and may not develop such strong or long-lasting responses to vaccination as people in the general population
Aims
This project aimed to recruit 50 people with vasculitis and rare autoimmune rheumatic diseases and measure their immunological (antibody and T-cell) responses to COVID-19 vaccination and compare these to age and sex-matched controls
Publications
Gumber, L., Jackson, H., Gomez, N., Hopkins, G., Tucis, D., Chakravorty, M., Tighe, P., Grainge, M., Rutter, M., Ferraro, A., Power, S., Pradère, M.-J., Lanyon, P. C., Pearce, F. A., & Fairclough, L. (2023). Antibody response to four doses of SARS-CoV-2 vaccine in rare autoimmune rheumatic diseases: an observational study. Rheumatology Advances in Practice, rkad097. https://doi.org/10.1093/rap/rkad097
Gumber L, Gomez N, Hopkins G et al. Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV-2 vaccination. Rheumatology 2022. https://doi.org/10.1093/rheumatology/keac574