N GOMEZ, V JAMES, KP ARKILL, ZA NIZAMUDEEN, D ONION and LC FAIRCLOUGH, 2023. PBMC derived extracellular vesicles in a smoking-related inflammatory disease model European Journal of Immunology. GV HOPKINS, S COCHRANE, D ONION and LC FAIRCLOUGH, 2022. The Role of Lipids in Allergic Sensitization: A Systematic Review Front. Mol. Biosci. L GUMBER, N GOMEZ, G HOPKINS, D TUCIS, L BARTLETT, L AYLING, K VEDHARA, G STEERS, M CHAKRAVORTY, M RUTTER, H JACKSON, PJ TIGHE, A FERRARO, S POWER, M-J PRADERE, D ONION, P LANYON, F PEARCE and LC FAIRCLOUGH, 2022. Humoral and cellular immunity in patients with rare autoimmune rheumatic diseases following SARS-CoV2 vaccination. Rheumatology. A HAMED, I TODD, PJ TIGHE, RJ POWELL, T HARRISON and LC FAIRCLOUGH, 2021. Array-based measurements of aero-allergen-specific IgE correlate with skin-prick test reactivity in asthma regardless of specific IgG4 or total IgE measurements Journal of Immunological Methods.
P SANGAPHUNCHAI, I TODD and LC FAIRCLOUGH, 2020. Extracellular vesicles and asthma: A review of the literature Clin Exp Allergy. I-L CHEN, PJ TIGHE, I TODD and L FAIRCLOUGH, 2020. Electronic cigarette vapour moderately stimulates pro-inflammatory signalling pathways and interleukin-6 production by human monocyte-derived dendritic cells Arch Tox.
I TODD, RE THOMAS, BD WATT, L SUTHERLAND, A AFRIYIE-ASANTE, B DEB, B JOSEPH, PJ TIGHE, P LANYON and LC FAIRCLOUGH, 2020. Multiple pathways of type 1 interferon production in lupus: the case for amlexanox. Rheumatology.
VEDHARA, K., AYLING, K., SUNGER, K., CALDWELL, D.M., HALLIDAY, V., FAIRCLOUGH, L., AVERY, A., ROBLES, L., GARIBALDI, J., WELTON, N.J. and ROYAL, S., 2019. Psychological Interventions as Vaccine Adjuvants: a systematic review. Vaccine. 37(25), 3255-3266 AYLING, K., FAIRCLOUGH, L., BUCHANAN, H., WETHERELL, M.A. and VEDHARA, K., 2019. Mood and influenza vaccination in older adults: A randomized controlled trial Health Psychology. Epub ahead of print: 5 August 2019, BYRNE R, TODD I, TIGHE PJ and FAIRCLOUGH LC, 2019. Autoantibodies in chronic obstructive pulmonary disease: A systematic review. Immunology letters. 214, 8-15 NEGM OH, SINGH S, ABDULJABBAR W, HAMED MR, RADFORD P, MCDERMOTT EM, DREWE E, FAIRCLOUGH L, TODD I and TIGHE PJ, 2019. Patients with tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) are hypersensitive to Toll-like receptor 9 stimulation. Clinical and experimental immunology. 197(3), 352-360 CHEN IL, TODD I and FAIRCLOUGH LC, 2019. Immunological and pathological effects of electronic cigarettes. Basic & clinical pharmacology & toxicology. 125(3), 237-252 WANG R, PSCHEID R, GHUMRA A, KAN LYL, COCHRANE S, FAIRCLOUGH L and ALCOCER MJC, 2019. Towards a surrogate system to express human lipid binding TCRs. Biotechnology letters. 41(10), 1095-1104 AYLING K, FAIRCLOUGH L, TIGHE P, TODD I, HALLIDAY V, GARIBALDI J, ROYAL S, HAMED A, BUCHANAN H and VEDHARA K, 2018. Positive Mood on the Day of Influenza Vaccination Predicts Vaccine Effectiveness: A Prospective Observational Cohort Study. Brain, behavior, and immunity. 314-23 AYLING, K., FAIRCLOUGH, L., TIGHE, P., TODD, I., HALLIDAY, V., GARIBALDI, J.M., ROYAL, S., HAMED, A., BUCHANAN, H. and VEDHARA, K., 2018. Positive mood on the day of influenza vaccination predicts vaccine effectiveness: A prospective observational cohort study. Brain, Behavior, and Immunity. 67, 314-323 LIANGLIANG LIU, LEONEL MARQUES, RICARDO CORREIA, STEPHEN P. MORGAN, SEUNG-WOO LEE, PADDY TIGHE, LUCY FAIRCLOUGH and SERHIY KORPOSH, 2018. Highly sensitive label-free antibody detection using a long period fibre grating sensor Sensors and Actuators B: Chemical. 271, 24 - 32 SANIKLIDOU, ARIADNE HADJIKYRIACOU, TIGHE, PATRICK J., FAIRCLOUGH, LUCY C. and TODD, IAN, 2018. IgE autoantibodies and their association with the disease activity and phenotype in bullous pemphigoid: a systematic review ARCHIVES OF DERMATOLOGICAL RESEARCH. 310(1), 11-28 TUBBY C, NEGM OH, HARRISON T, TIGHE PJ, TODD I and FAIRCLOUGH LC, 2017. Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction. The Journal of asthma : official journal of the Association for the Care of Asthma. 54(5), 456-466 AYLING K, BOWDEN T, TIGHE P, TODD I, DILNOT EM, NEGM OH, FAIRCLOUGH L and VEDHARA K, 2017. The application of protein microarray assays in psychoneuroimmunology. Brain, behavior, and immunity. 59, 62-66 TODD I, NEGM OH, REPS J, RADFORD P, FIGUEREDO G, MCDERMOTT EM, DREWE E, POWELL RJ, BAINBRIDGE S, HAMED M, CROUCH S, GARIBALDI J, ST-GALLAY S, FAIRCLOUGH LC and TIGHE PJ, 2017. A signalome screening approach in the autoinflammatory disease TNF Receptor Associated Periodic Syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing. Pharmacological Research. SHINDI R, ALMEHAIRI A, NEGM OH, KALSHEKER N, GALE NS, SHALE DJ, HARRISON TW, BOLTON CE, JOHN M, TODD I, TIGHE PJ and FAIRCLOUGH LC, 2017. Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease. Clinical immunology (Orlando, Fla.). (In Press.)
SELVARAJAH S, TODD I, TIGHE PJ, JOHN M, BOLTON CE, HARRISON T and FAIRCLOUGH LC, 2016. Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease. Mediators of inflammation. 2016, 3604842 TIGHE, P. J., RYDER, R. R., TODD, I. and FAIRCLOUGH, L. C., 2015. ELISA in the multiplex era: potentials and pitfalls: Proteomics Clin Appl Proteomics Clin Appl. 9(3-4), 406-22 GALOZZI, P., NEGM, O., GRECO, E., ALKHATTABI, N., GAVA, A., SFRISO, P., FAIRCLOUGH, L., TODD, I., TIGHE, P. and PUNZI, L., 2015. Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome: Reumatismo Reumatismo. 66(4), 277-84 DAFFA, N. I., TIGHE, P. J., CORNE, J. M., FAIRCLOUGH, L. C. and TODD, I., 2015. Natural and disease-specific autoantibodies in chronic obstructive pulmonary disease: Clin Exp Immunol Clin Exp Immunol. 180(1), 155-63 SELVARAJAH S, NEGM OH, HAMED MR, TUBBY C, TODD I, TIGHE PJ, HARRISON T and FAIRCLOUGH LC, 2014. Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators of inflammation. 2014, 820304 ALOTIBY, A. A., FAIRCLOUGH, L. C., TODD, I. and TIGHE, P. J., 2014. Generation and characterisation of transcription activator-like effector nucleases (TALENs) targeting TNFR1 genome editing IMMUNOLOGY. 143, 95-95
HALALA, R. A., TIGHE, P., TODD, I. and FAIRCLOUGH, L., 2014. Profiling of natural autoantibodies in relation to chronic obstructive pulmonary disease IMMUNOLOGY. 143, 79-79
TARBIAH, N., TIGHE, P., FAIRCLOUGH, L. and TODD, I., 2014. Comparing between smokers and non-smokers immunoglobulin levels and B-cell differentiation IMMUNOLOGY. 143, 81-81
ALBOGAMI, S., NEGM, O., ZANG, L., THOMAS, N., FAIRCLOUGH, L., TODD, I. and TIGHE, P., 2014. The inhibitory effects of recombinant PLAD wild type (WT) protein on the inflammatory signalling pathways IMMUNOLOGY. 143, 125-125
HAMED, A., TODD, I., TIGHE, P., POWELL, R. and FAIRCLOUGH, L., 2014. Development of IgE microarray assays for classification of allergic individuals IMMUNOLOGY. 143, 170-170
NEGM OH, MANNSPERGER HA, MCDERMOTT EM, DREWE E, POWELL RJ, TODD I, FAIRCLOUGH LC and TIGHE PJ, 2014. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS). European journal of immunology. 44(7), 2096-110 TODD I, BURR S, WHITTLE J and FAIRCLOUGH L, 2014. Modifying the Hofstee method may overcome problems. Medical teacher. 36(4), 358-9 TIGHE, P., NEGM, O., TODD, I. and FAIRCLOUGH, L., 2013. Utility, reliability and reproducibility of immunoassay multiplex kits Methods. 61(1), 23-29 WANG, J., URBANOWICZ, R.A., TIGHE, P.J., TODD, I., CORNE, J.M. and FAIRCLOUGH, L.C., 2013. Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD) PLoS ONE. 8(3), e58556 TUBBY, C., HARRISON, T., TODD, I. and FAIRCLOUGH, L., 2011. Immunological basis of reversible and fixed
airways disease Clinical Science. 121(7), 285-296 RICHENS, J.L., URBANOWICZ, R.A., METCALF, R., CORNE, J., O’SHEA, P. and FAIRCLOUGH, L., 2010. Quantitative validation and comparison of multiplex cytokine kits Journal of Biomolecular Screening. 15(5), 562-568 URBANOWICZ, R.A., LAMB, J.R., TODD, I., CORNE, J.M. and FAIRCLOUGH, L.C., 2010. Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients Respiratory Research. 11, 76 HASAN, A.A., GHAEMMAGHAMI, A.M., FAIRCLOUGH, L., ROBINS, A., SEWELL, H.F. and SHAKIB, F., 2009. Allergen-driven suppression of thiol production by human dendritic cells and the effect of thiols on T cell function Immunobiology. 214(1), 2-16 RICHENS, JOANNA L, URBANOWICZ, RICHARD A, LUNT, ELIZABETH A M, METCALF, REBECCA, CORNE, JONATHAN, FAIRCLOUGH, LUCY and O'SHEA, PAUL, 2009. Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease. Respiratory Research. 10, 29 URBANOWICZ, R.A, LAMB, J.R., TODD, I., CORNE, J.M. and FAIRCLOUGH, L.C., 2009. Altered effector function of peripheral cytotoxic cells in COPD Respiratory Research. 10(June), 53 FAIRCLOUGH, L., URBANOWICZ, R.A., CORNE, J. and LAMB, J.R., 2008. Killer cells in chronic obstructive pulmonary disease Clinical Science. 114(8), 533-541 RICHENS, J., FAIRCLOUGH, L., GHAEMMAGHAMI, A.M., MAHDAVI, J., SHAKIB, F. and SEWELL, H.F., 2007. The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets Immunobiology. 212(1), 29-38 HARRIS, J., MASON, D.E., LI, J., BURDICK, K.W., BACKES, B.J., CHEN, T., SHIPWAY, A., VAN HEEKE, G., GOUGH, L., GHAEMMAGHAMI, A., SHAKIB, F., DEBAENE, F. and WINSSINGER, N., 2004. Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays Chemistry & Biology. 11(10), 1361-1372 GOUGH, L., CAMPBELL, E., BAYLEY, D., VAN HEEKE, G. and SHAKIB, F., 2003. Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model Clinical and Experimental Allergy. 33(8), 1159-1163 FURTADO, P.B., MCELVEEN, J.E., GOUGH, L., ARMOUR, K.L., CLARK, M.R., SEWELL, H.F. and SHAKIB, F., 2002. The production and characterisation of a chimaeric human IgE antibody, recognising the major mite allergen Der p 1, and its chimaeric human IgG1 anti-idiotype Molecular Pathology. 55(5), 315-324 SHAKIB F, SCHULZ O, GOUGH L AND GHAEMMAGHAMI A.M., 2002. The role of the enzymatic activity of the house dust mite antigen Der p 1 in enhancing its allergenicity Eur. Respir. Mon. 21, 153-160
GHAEMMAGHAMI, A.M., ROBINS, A., GOUGH, L., SEWELL, H.F. and SHAKIB, F., 2001. Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-γ European Journal of Immunology. 31(4), 1211-1216 SHAKIB, F and GOUGH, L, 2000. The proteolytic activity of Der p 1 selectively enhances IgE synthesis: a link between allergenicity and cysteine protease activity. Clinical and Experimental Allergy. 30(6), 751-2