VEDHARA, K, AYLING, K, JIA, R, FAIRCLOUGH, L, MORLING, JR, BLAKE, H, CORNER, J, DENNING, C, BOLTON, C, JACKSON, H, COUPLAND, C and TIGHE, P, 2022. Relationship between Anxiety, Depression and Susceptibility to SARS-CoV-2 Infection: Proof of Concept The Journal of Infectious Diseases. 225(12), 2137-2141 TURNBULL, JAMES, JHA, RAKESH, ORTORI, CATHERINE A, LUNT, ELEANOR, TIGHE, PATRICK J, IRVING, WILLIAM L, GOHIR, SAMEER A, KIM, DONG-HYUN, VALDES, ANA M, TARR, ALEXANDER W, BARRETT, DAVID A and CHAPMAN, VICTORIA, 2022. Serum levels of pro-inflammatory lipid mediators and specialised pro-resolving molecules are increased in SARS-CoV-2 patients and correlate with markers of the adaptive immune response The Journal of Infectious Diseases. SCURR, M. J., ZELEK, W. M., LIPPIATT, G., SOMERVILLE, M., BURNELL, S. E. A., CAPITANI, L., DAVIES, K., LAWTON, H., TOZER, T., REES, T., ROBERTS, K., EVANS, M., JACKSON, A., YOUNG, C., FAIRCLOUGH, L., TIGHE, P., WILLS, M., WESTWELL, A. D., MORGAN, B. P., GALLIMORE, A. and GODKIN, A., 2022. Whole blood-based measurement of SARS-CoV-2-specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid-organ cancers: Immunology Immunology. 165(2), 250-259 GALOZZI, P., NEGM, O., BINDOLI, S., TIGHE, P., SFRISO, P. and PUNZI, L., 2022. A Pro-Inflammatory Signature Constitutively Activated in Monogenic Autoinflammatory Diseases: Int J Mol Sci Int J Mol Sci. 23(3), CHAPPELL, H., PATEL, R., DRIESSENS, C., TARR, A. W., IRVING, W. L., TIGHE, P. J., JACKSON, H. J., HARVEY-COWLISHAW, T., MILLS, L., SHAUNAK, M., GBESEMETE, D., LEAHY, A., LUCAS, J. S., FAUST, S. N. and DE GRAAF, H., 2022. Immunocompromised children and young people are at no increased risk of severe COVID-19: J Infect J Infect. 84(1), 31-39 ASTBURY, S., REYNOLDS, C. J., BUTLER, D. K., MUNOZ-SANDOVAL, D. C., LIN, K. M., PIEPER, F. P., OTTER, A., KOURAKI, A., CUSIN, L., NIGHTINGALE, J., VIJAY, A., CRAXFORD, S., AITHAL, G. P., TIGHE, P. J., GIBBONS, J. M., PADE, C., JOY, G., MAINI, M., CHAIN, B., SEMPER, A., BROOKS, T., OLLIVERE, B. J., MCKNIGHT, A., NOURSADEGHI, M., TREIBEL, T. A., MANISTY, C., MOON, J. C., C. OVIDSORTIUM INVESTIGATORS, VALDES, A. M., BOYTON, R. J. and ALTMANN, D. M., 2022. HLA-DR polymorphism in SARS-CoV-2 infection and susceptibility to symptomatic COVID-19: Immunology Immunology. VEDHARA, K., AYLING, K., JIA, R., FAIRCLOUGH, L., MORLING, J. R., BALL, J. K., KNIGHT, H., BLAKE, H., CORNER, J., DENNING, C., BOLTON, K., JACKSON, H., COUPLAND, C. and TIGHE, P., 2022. Relationship between Anxiety, Depression and Susceptibility to SARS-CoV-2 Infection: Proof of Concept: J Infect Dis J Infect Dis. VEDHARA, K., AYLING, K., JIA, R., FAIRCLOUGH, L., MORLING, J. R., BALL, J. K., KNIGHT, H., BLAKE, H., CORNER, J., DENNING, C., BOLTON, K., JACKSON, H., COUPLAND, C. and TIGHE, P., 2022. Relationship between Anxiety, Depression and Susceptibility to SARS-CoV-2 Infection: Proof of Concept: J Infect Dis J Infect Dis. VOYSEY, M., COSTA CLEMENS, S. A., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., CLUTTERBUCK, E. A., COLLINS, A. M., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DOLD, C., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FLAXMAN, A., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GALIZA, E., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., GREENLAND, M., HILL, C., HILL, H. C., HIRSCH, I., IZU, A., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LIBRI, V., LILLIE, P. J., MARCHEVSKY, N. G., MARSHALL, R. P., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MUJADIDI, Y. F., NANA, A., PADAYACHEE, S. D., PHILLIPS, D. J., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RITCHIE, A. J., ROBINSON, H., SCHWARZBOLD, A. V., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WHITE, T., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials: Lancet Lancet. 397(10277), 881-891 VOYSEY, M., CLEMENS, S. A. C., MADHI, S. A., WECKX, L. Y., FOLEGATTI, P. M., ALEY, P. K., ANGUS, B., BAILLIE, V. L., BARNABAS, S. L., BHORAT, Q. E., BIBI, S., BRINER, C., CICCONI, P., COLLINS, A. M., COLIN-JONES, R., CUTLAND, C. L., DARTON, T. C., DHEDA, K., DUNCAN, C. J. A., EMARY, K. R. W., EWER, K. J., FAIRLIE, L., FAUST, S. N., FENG, S., FERREIRA, D. M., FINN, A., GOODMAN, A. L., GREEN, C. M., GREEN, C. A., HEATH, P. T., HILL, C., HILL, H., HIRSCH, I., HODGSON, S. H. C., IZU, A., JACKSON, S., JENKIN, D., JOE, C. C. D., KERRIDGE, S., KOEN, A., KWATRA, G., LAZARUS, R., LAWRIE, A. M., LELLIOTT, A., LIBRI, V., LILLIE, P. J., MALLORY, R., MENDES, A. V. A., MILAN, E. P., MINASSIAN, A. M., MCGREGOR, A., MORRISON, H., MUJADIDI, Y. F., NANA, A., O'REILLY, P. J., PADAYACHEE, S. D., PITTELLA, A., PLESTED, E., POLLOCK, K. M., RAMASAMY, M. N., RHEAD, S., SCHWARZBOLD, A. V., SINGH, N., SMITH, A., SONG, R., SNAPE, M. D., SPRINZ, E., SUTHERLAND, R. K., TARRANT, R., THOMSON, E. C., TOROK, M. E., TOSHNER, M., TURNER, D. P. J., VEKEMANS, J., VILLAFANA, T. L., WATSON, M. E. E., WILLIAMS, C. J., DOUGLAS, A. D., HILL, A. V. S., LAMBE, T., GILBERT, S. C., POLLARD, A. J. and OXFORD, COVID VACCINE TRIAL GROUP, 2021. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK: Lancet Lancet. 397(10269), 99-111 VALDES, ANA M., MOON, JAMES C., VIJAY, AMRITA, CHATURVEDI, NISH, NORRISH, ALAN, IKRAM, ADEEL, CRAXFORD, SIMON, CUSIN, LOLA M. L., NIGHTINGALE, JESSICA, SEMPER, AMANDA, BROOKS, TIMOTHY, MCKNIGHT, AINE, KURDI, HIBBA, MENNI, CRISTINA, TIGHE, PATRICK, NOURSADEGHI, MAHDAD, AITHAL, GURUPRASAD, TREIBEL, THOMAS A., OLLIVERE, BENJAMIN J. and MANISTY, CHARLOTTE, 2021. Longitudinal assessment of symptoms and risk of SARS-CoV-2 infection in healthcare workers across 5 hospitals to understand ethnic differences in infection risk: EClinicalMedicine EClinicalMedicine. 100835 HAMED, A., TODD, I., TIGHE, P. J., POWELL, R. J., HARRISON, T. and FAIRCLOUGH, L. C., 2021. Array-based measurements of aero-allergen-specific IgE correlate with skin-prick test reactivity in asthma regardless of specific IgG4 or total IgE measurements: J Immunol Methods J Immunol Methods. 492, 112999 ALLEN, C. M., RAMSAMY, S., TARR, A. W., TIGHE, P. J., IRVING, W. L., TANASESCU, R. and EVANS, J. R., 2021. Guillain-Barre Syndrome Variant Occurring after SARS-CoV-2 Vaccination: Ann Neurol Ann Neurol. 90(2), 315-318 URBANOWICZ, RICHARD A., TSOLERIDIS, THEOCHARIS, JACKSON, HANNAH J., CUSIN, LOLA, DUNCAN, JOSHUA D., CHAPPELL, JOSEPH G., TARR, ALEXANDER W., NIGHTINGALE, JESSICA, NORRISH, ALAN R., IKRAM, ADEEL, MARSON, BEN, CRAXFORD, SIMON J., KELLY, ANTHONY, AITHAL, GURUPRASAD P., VIJAY, AMRITA, TIGHE, PATRICK J., BALL, JONATHAN K., VALDES, ANA M. and OLLIVERE, BENJAMIN J., 2021. Two doses of the SARS-CoV-2 BNT162b2 vaccine enhance antibody responses to variants in individuals with prior SARS-CoV-2 infection SCIENCE TRANSLATIONAL MEDICINE. 13(609), TODD, I., THOMAS, R. E., WATT, B. D., SUTHERLAND, L., AFRIYIE-ASANTE, A., DEB, B., JOSEPH, B., TIGHE, P. J., LANYON, P. and FAIRCLOUGH, L. C., 2020. Multiple pathways of type 1 interferon production in lupus: the case for amlexanox: Rheumatology (Oxford) Rheumatology (Oxford). 59(12), 3980-3982 TIGHE, PATRICK J., URBANOWICZ, RICHARD A., FAIRCLOUGH, C. LUCY, MCCLURE, C. PATRICK, THOMSON, BRIAN J., GOMEZ, NANCY, CHAPPELL, JOSEPH G., TSOLERIDIS, THEOCHARIS, LOOSE, MATTHEW, CARLILE, MATTHEW, MOORE, CHRISTOPHER, HOLMES, NADINE, SANG, FEI, HRUSHIKESH, DIVYATEJA, CLARK, GEMMA, TEMPERTON, NIGEL, BROOKS, TIM, BALL, JONATHAN K., IRVING, WILLIAM L. and TARR, ALEXANDER W., 2020. Potent anti-SARS-CoV-2 Antibody Responses are Associated with Better Prognosis in Hospital Inpatient COVID-19 Disease: medRxiv medRxiv. 2020.08.22.20176834 LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAIVA, ANA CAROLINA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2019. Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas Aeruginosa With Bronchial Epithelial Cells (vol 9, 3018, 2018) FRONTIERS IN MICROBIOLOGY. 10, BYRNE, RACHEL, TODD, IAN, TIGHE, PATRICK J and FAIRCLOUGH, LUCY C, 2019. Autoantibodies in chronic obstructive pulmonary disease: A systematic review. Immunology letters. 214, 8-15 TARBIAH, NESRIN, TODD, IAN, TIGHE, PATRICK J and FAIRCLOUGH, LUCY C, 2019. Cigarette smoking differentially affects immunoglobulin class levels in serum and saliva: An investigation and review. Basic & clinical pharmacology & toxicology. NEGM, O. H., SINGH, S., ABDULJABBAR, W., HAMED, M. R., RADFORD, P., MCDERMOTT, E. M., DREWE, E., FAIRCLOUGH, L., TODD, I and TIGHE, P. J., 2019. Patients with tumour necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) are hypersensitive to Toll-like receptor 9 stimulation CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 197(3), 352-360 AYLING K, FAIRCLOUGH L, TIGHE P, TODD I, HALLIDAY V, GARIBALDI J, ROYAL S, HAMED A, BUCHANAN H and VEDHARA K, 2018. Positive Mood on the Day of Influenza Vaccination Predicts Vaccine Effectiveness: A Prospective Observational Cohort Study. Brain, behavior, and immunity. 314-23 LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. Data_Sheet_1_Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells.PDF Figshare.
LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. Data_Sheet_2_Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells.PDF Figshare.
LIU, YI-CHIA, HUSSAIN, FARAH, NEGM, OLA, PAVIA, ANA, HALLIDAY, NIGEL, DUBERN, JEAN-FREDERIC, SINGH, SONALI, MUNTAKA, SIRINA, WHELDON, LEE, LUCKETT, JENI, TIGHE, PADDY, BOSQUILLON, CYNTHIA, WILLIAMS, PAUL, CAMARA, MIGUEL and MARTINEZ-POMARES, LUISA, 2018. Contribution of the Alkylquinolone Quorum-Sensing System to the Interaction of Pseudomonas aeruginosa With Bronchial Epithelial Cells FRONTIERS IN MICROBIOLOGY. 9, TUBBY C, NEGM OH, HARRISON T, TIGHE PJ, TODD I and FAIRCLOUGH LC, 2017. Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction. The Journal of asthma : official journal of the Association for the Care of Asthma. 54(5), 456-466 AYLING K, BOWDEN T, TIGHE P, TODD I, DILNOT EM, NEGM OH, FAIRCLOUGH L and VEDHARA K, 2017. The application of protein microarray assays in psychoneuroimmunology. Brain, behavior, and immunity. 59, 62-66 TODD I, NEGM OH, REPS J, RADFORD P, FIGUEREDO G, MCDERMOTT EM, DREWE E, POWELL RJ, BAINBRIDGE S, HAMED M, CROUCH S, GARIBALDI J, ST-GALLAY S, FAIRCLOUGH LC and TIGHE PJ, 2017. A signalome screening approach in the autoinflammatory disease TNF Receptor Associated Periodic Syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing. Pharmacological Research. NEGM, O. H., MUFTAH, A. A., ALESKANDARANY, M. A., HAMED, M. R., AHMAD, D. A., NOLAN, C. C., DIEZ-RODRIGUEZ, M., TIGHE, P. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. Clinical utility of reverse phase protein array for molecular classification of breast cancer: Breast Cancer Res Treat Breast cancer research and treatment. 155(1), 25-35 ALESKANDARANY, M. A., AGARWAL, D., NEGM, O. H., BALL, G., ELMOUNA, A., ASHANKYTY, I., NUGLOZEH, E., FAZALUDEEN, M. F., DIEZ-RODRIGUEZ, M., NOLAN, C. C., TIGHE, P. J., GREEN, A. R., ELLIS, I. O. and RAKHA, E. A., 2016. The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts: Breast Cancer Res Treat Breast cancer research and treatment. SENTHOORAN SELVARAJAH, IAN TODD, PATRICK TIGHE, MICHELLE JOHN, CHARLOTTE E. BOLTON, TIM HARRISON and LUCY FAIRCLOUGH, 2016. Multiple circulating cytokines are co-elevated in chronic obstructive pulmonary disease. (In Press.)
SALAZAR, F., HALL, L., NEGM, O. H., AWUAH, D., TIGHE, P. J., SHAKIB, F. and GHAEMMAGHAMI, A. M., 2016. The mannose receptor negatively modulates the Toll-like receptor 4-aryl hydrocarbon receptor-indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization: J Allergy Clin Immunol J Allergy Clin Immunol. 137(6), 1841-1851 e2 MOZ S, BASSO D, BOZZATO D, GALOZZI P, NAVAGLIA F, NEGM OH, ARRIGONI G, ZAMBON CF, PADOAN A, TIGHE P, TODD I, FRANCHIN C, PEDRAZZOLI S, PUNZI L and PLEBANI M, 2016. SMAD4 loss enables EGF, TGFβ1 and S100A8/A9 induced activation of critical pathways to invasion in human pancreatic adenocarcinoma cells. Oncotarget. (In Press.)
ABDULJABBAR R, AL-KAABI MM, NEGM OH, JERJEES D, MUFTAH AA, MUKHERJEE A, LAI CF, BULUWELA L, ALI S, TIGHE PJ, GREEN A, ELLIS I and RAKHA E, 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer. Breast cancer research and treatment. 150(3), 511-22 ABDULJABBAR R, NEGM OH, LAI C, JERJEES DA, AL-KAABI M, HAMED MR, TIGHE PJ, BULUWELA L, MUKHERJEE A, GREEN AR, ALI S, RAKHA EA and ELLIS IO, 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Breast cancer research and treatment. 150(2), 335-46 JERJEES DA, NEGM OH, ALABDULLAH ML, MIRZA S, ALKAABI M, HAMEED MR, ABDULJABBAR R, MUFTAH A, NOLAN CC, GREEN AR, TIGHE PJ, BAND V, ELLIS IO and RAKHA EA, 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways. Breast cancer research and treatment. 150(1), 91-103 JEAN-GILLES L, BRAITCH M, LATIF ML, ARAM J, FAHEY AJ, EDWARDS LJ, ROBINS RA, TANASESCU R, TIGHE PJ, GRAN B, SHOWE LC, ALEXANDER SP, CHAPMAN V, KENDALL DA and CONSTANTINESCU CS, 2015. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells. Acta physiologica (Oxford, England). 214(1), 63-74 VILISAAR J, KAWABE K, BRAITCH M, ARAM J, FURTUN Y, FAHEY AJ, CHOPRA M, TANASESCU R, TIGHE PJ, GRAN B, POTHOULAKIS C and CONSTANTINESCU CS, 2015. Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. PMID: 25690155, ALSHAREEDA, A. T., NEGM, O. H., GREEN, A. R., NOLAN, C. C., TIGHE, P., ALBARAKATI, N., SULTANA, R., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer: Br J Cancer Br J Cancer. 112(12), 1929-37 VILISAAR, J., KAWABE, K., BRAITCH, M., ARAM, J., FURTUN, Y., FAHEY, A. J., CHOPRA, M., TANASESCU, R., TIGHE, P. J., GRAN, B., POTHOULAKIS, C. and CONSTANTINESCU, C. S., 2015. Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNgamma/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis: J Neuroimmune Pharmacol J Neuroimmune Pharmacol. TIGHE, P. J., RYDER, R. R., TODD, I. and FAIRCLOUGH, L. C., 2015. ELISA in the multiplex era: potentials and pitfalls: Proteomics Clin Appl Proteomics Clin Appl. 9(3-4), 406-22 NEGM, O. H., HAMED, M. R., DILNOT, E. M., SHONE, C. C., MARSZALOWSKA, I., LYNCH, M., LOSCHER, C. E., EDWARDS, L. J., TIGHE, P. J., WILCOX, M. H. and MONAGHAN, T. M., 2015. Profiling Humoral Immune Responses to Clostridium difficile-Specific Antigens by Protein Microarray Analysis: Clin Vaccine Immunol Clin Vaccine Immunol. JERJEES, D. A., NEGM, O. H., ALABDULLAH, M. L., MIRZA, S., ALKAABI, M., HAMEED, M. R., ABDULJABBAR, R., MUFTAH, A., NOLAN, C. C., GREEN, A. R., TIGHE, P. J., BAND, V., ELLIS, I. O. and RAKHA, E. A., 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways: Breast Cancer Res Treat Breast cancer research and treatment. 150(1), 91-103 JEAN-GILLES, L., BRAITCH, M., LATIF, M. L., ARAM, J., FAHEY, A. J., EDWARDS, L. J., ROBINS, R. A., TANASESCU, R., TIGHE, P. J., GRAN, B., SHOWE, L. C., ALEXANDER, S. P., CHAPMAN, V., KENDALL, D. A. and CONSTANTINESCU, C. S., 2015. Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells: Acta Physiol (Oxf) Acta Physiol (Oxf). 214(1), 63-74 HEATH, C. J., DEL MAR CENDRA, M., WATSON, A., AUGER, J. P., PANDEY, A., TIGHE, P. and CHRISTODOULIDES, M., 2015. Co-Transcriptomes of Initial Interactions In Vitro between Streptococcus Pneumoniae and Human Pleural Mesothelial Cells: PLoS One PLoS One. 10(11), e0142773 GRECO, E., AITA, A., GALOZZI, P., GAVA, A., SFRISO, P., NEGM, O. H., TIGHE, P., CASO, F., NAVAGLIA, F., DAZZO, E., DE BORTOLI, M., RAMPAZZO, A., OBICI, L., DONADEI, S., MERLINI, G., PLEBANI, M., TODD, I., BASSO, D. and PUNZI, L., 2015. The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-kappaB pathway: Arthritis Res Ther Arthritis Res Ther. 17(1), 93 GALOZZI, P., NEGM, O., GRECO, E., ALKHATTABI, N., GAVA, A., SFRISO, P., FAIRCLOUGH, L., TODD, I., TIGHE, P. and PUNZI, L., 2015. Ex vivo and in vitro production of pro-inflammatory cytokines in Blau syndrome: Reumatismo Reumatismo. 66(4), 277-84 FAIRCLOUGH, L. C., STOOP, A. A., NEGM, O. H., RADFORD, P. M., TIGHE, P. J. and TODD, I., 2015. Tumor Necrosis Factor Receptor I blockade shows that TNF-dependent and independent mechanisms synergise in TNF Receptor Associated Periodic Syndrome: Eur J Immunol Eur J Immunol. DAFFA, N. I., TIGHE, P. J., CORNE, J. M., FAIRCLOUGH, L. C. and TODD, I., 2015. Natural and disease-specific autoantibodies in chronic obstructive pulmonary disease: Clin Exp Immunol Clin Exp Immunol. 180(1), 155-63 ABDULJABBAR, R., NEGM, O. H., LAI, C. F., JERJEES, D. A., AL-KAABI, M., HAMED, M. R., TIGHE, P. J., BULUWELA, L., MUKHERJEE, A., GREEN, A. R., ALI, S., RAKHA, E. A. and ELLIS, I. O., 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer: Breast Cancer Res Treat Breast cancer research and treatment. 150(2), 335-46 ABDULJABBAR, R., AL-KAABI, M. M., NEGM, O. H., JERJEES, D., MUFTAH, A. A., MUKHERJEE, A., LAI, C. F., BULUWELA, L., ALI, S., TIGHE, P. J., GREEN, A., ELLIS, I. and RAKHA, E., 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer: Breast Cancer Res Treat Breast cancer research and treatment. 150(3), 511-22 ALSHAREEDA AT, NEGM OH, GREEN AR, NOLAN C, TIGHE P, ALBARAKATI N, SULTANA R, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2014. SUMOylation proteins in breast cancer. Breast cancer research and treatment. 144(3), 519-30 ALESKANDARANY MA, NEGM OH, GREEN AR, AHMED MAH, NOLAN CC, TIGHE PJ, ELLIS IO and RAKHA EA, 2014. Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study. Breast cancer research and treatment. 145(2), 339-48 SELVARAJAH S, NEGM OH, HAMED MR, TUBBY C, TODD I, TIGHE PJ, HARRISON T and FAIRCLOUGH LC, 2014. Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators of inflammation. 2014, 820304 ALOTIBY, A. A., FAIRCLOUGH, L. C., TODD, I. and TIGHE, P. J., 2014. Generation and characterisation of transcription activator-like effector nucleases (TALENs) targeting TNFR1 genome editing IMMUNOLOGY. 143, 95-95
HALALA, R. A., TIGHE, P., TODD, I. and FAIRCLOUGH, L., 2014. Profiling of natural autoantibodies in relation to chronic obstructive pulmonary disease IMMUNOLOGY. 143, 79-79
TARBIAH, N., TIGHE, P., FAIRCLOUGH, L. and TODD, I., 2014. Comparing between smokers and non-smokers immunoglobulin levels and B-cell differentiation IMMUNOLOGY. 143, 81-81
ALBOGAMI, S., NEGM, O., ZANG, L., THOMAS, N., FAIRCLOUGH, L., TODD, I. and TIGHE, P., 2014. The inhibitory effects of recombinant PLAD wild type (WT) protein on the inflammatory signalling pathways IMMUNOLOGY. 143, 125-125
HAMED, A., TODD, I., TIGHE, P., POWELL, R. and FAIRCLOUGH, L., 2014. Development of IgE microarray assays for classification of allergic individuals IMMUNOLOGY. 143, 170-170
NEGM OH, MANNSPERGER HA, MCDERMOTT EM, DREWE E, POWELL RJ, TODD I, FAIRCLOUGH LC and TIGHE PJ, 2014. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS). European journal of immunology. 44(7), 2096-110 GALOZZI, P., GRECO, E., GAVA, A., BASSO, D., SFRISO, P., TIGHE, P., TODD, I. and PUNZI, L., 2014. FUNCTIONAL CHARACTERIZATION OF P.E383K BLAU SYNDROME-RELATED MUTATION ANNALS OF THE RHEUMATIC DISEASES. 73, 807-807 JERJEES, D., NEJM, O., MIRZA, S., ABDULJABBAR, R., GREEN, A., TIGHE, P., BAND, V., ELLIS, I. and RAKHA, E., 2014. The biological and clinical significance of phosphorylated mTOR (pi3k/AKt pathway related) and its association with estrogen receptor and HER2 pathways VIRCHOWS ARCHIV. 465, S99-S99
ALESKANDARANY, MOHAMMED A., NEGM, OLA H., GREEN, ANDREW R., AHMED, MOHAMED A. H., NOLAN, CHRISTOPHER C., TIGHE, PATRICK J., ELLIS, IAN O. and RAKHA, EMAD A., 2014. Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study BREAST CANCER RESEARCH AND TREATMENT. 145(2), 339-348 NEGM, O., MUFTAH, A., GREEN, A., NOLAN, C., TIGHE, P., ELLIS, I. and RAKHA, E., 2014. Unlocking the pathological achieves: High-throughput proteomic study for FFPE tissue using RPPA VIRCHOWS ARCHIV. 465, S24-S25
NEGM, O., JERJEES, D., ALSHAREEDA, A., GREEN, A., BAND, V., MIRZA, S., TIGHE, P., ELLIS, I. and RAKHA, E., 2014. Proteomics of breast cancer VIRCHOWS ARCHIV. 465, S24-S24
JERJEES, D., NEJM, O., MIRZA, S., ABDULJABBAR, R., ALSUBHI, N., NOLAN, C., GREEN, A., TIGHE, P., BAND, V., ELLIS, I. and RAKHA, E., 2014. ERK1/2 expression in breast cancer: The impact of subcellular localisation VIRCHOWS ARCHIV. 465, S107-S107
CHOPRA C, DAVIES G, TAYLOR M, ANDERSON M, BAINBRIDGE S, TIGHE P and MCDERMOTT EM, 2014. Immune deficiency in Ataxia-Telangiectasia: a longitudinal study of 44 patients. Clinical and experimental immunology. 176(2), 275-82 TIGHE, P., NEGM, O., TODD, I. and FAIRCLOUGH, L., 2013. Utility, reliability and reproducibility of immunoassay multiplex kits Methods. 61(1), 23-29 ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., AHMED, M. A., NOLAN, C. C., BALL, G. R., CALDAS, C., GREEN, A. R., TIGHE, P. J. and ELLIS, I. O., 2012. TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome Breast cancer research and treatment. 136(2), 419-27 VAITLA, P.M., RADFORD, P.M., TIGHE, P.J., POWELL, R.J., MCDERMOTT, E.M., TODD, I. and DREWE, E., 2011. Role of interleukin-6 in a patient with tumor necrosis factor receptor–associated periodic syndrome: Assessment of outcomes following treatment with the anti–interleukin-6 receptor monoclonal antibody tocilizumab Arthritis and Rheumatism. 63(4), 1151-1155 DOZMOROV, I.M., JARVIS, J., SABAN, R., BENBROOK, D.M., WAKELAND, E., AKSENTIJEVICH, I., RYAN, J., CHIORAZZI, N., GUTHRIDGE, J.M., DREWE, E., TIGHE, P.J., CENTOLA, M. and LEFKOVITS, I., 2011. Internal standard-based analysis of microarray data2-Analysis of functional associations between HVE-genes Nucleic Acids Research. 39(18), 7881-7899 RENAULT, N. K., GADDIPATI, S. R., WULFERT, F., FALCONE, F. H., MIROTTI, L., TIGHE, P. J., WRIGHT, V. and ALCOCER, M. J., 2011. Multiple protein extract microarray for profiling human food-specific immunoglobulins A, M, G and E: J Immunol Methods J Immunol Methods. 364(1-2), 21-32 REBELO, S. L., RADFORD, P. M., BAINBRIDGE, S. E., TODD, I. and TIGHE, P. J., 2011. Functional consequences of disease-associated mutations in TNFR1 elucidated by transcriptome analysis: Adv Exp Med Biol Adv Exp Med Biol. 691, 461-70 KULKARNI, B.B., TIGHE, P.J., MOHAMMED, I., YEUNG, A.M., POWE, D.G., HOPKINSON, A., SHANMUGANATHAN, V.A. and DUA, H.S., 2010. Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics BMC Genomics. 11(September), 526 ROYER, P. J., EMARA, M., YANG, C., AL-GHOULEH, A., TIGHE, P., JONES, N., SEWELL, H. F., SHAKIB, F., MARTINEZ-POMARES, L. and GHAEMMAGHAMI, A. M., 2010. The mannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity: J Immunol J Immunol. 185(3), 1522-31 BARTON, S.J., KOPPELMAN, G.H., VONK, J.M., BROWNING, C.A., NOLTE, I.M., STEWART, C.E., BAINBRIDGE, S., MUTCH, S., ROSE-ZERILLI, M.J., POSTMA, D.S., MANIATIS, N., HENRY, A.P., HALL, I.P., HOLGATE, S.T., TIGHE, P., HOLLOWAY, J.W. and SAYERS, I., 2009. PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline Journal of Allergy and Clinical Immunology. 123(6), 1391-1400.e17 REBELO, S.L., AMEL-KASHIPAZ, M.R., RADFORD,, P.M., BAINBRIDGE, S.E., FIETS, R., FANG, J., MCDERMOTT, E.M., POWELL, R.J., TODD, I. and TIGHE, P.J., 2009. Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line Arthritis and Rheumatism. 60(1), 269-280 HOU, Q, CHAU, DYS, PRATOOMSOOT, C, TIGHE, PJ, DUA, HS, SHAKESHEFF, KM and ROSE, FRAJ, 2008. In situ gelling hydrogels incorporating microparticles as drug delivery carriers for regenerative medicine. Journal of Pharmaceutical Sciences. 97(9), 3972-3980 HALL, ANDREW J, MORROLL, SHAUN, TIGHE, PATRICK, GÖTZ, FRIEDRICH and FALCONE, FRANCO H, 2008. Human chitotriosidase is expressed in the eye and lacrimal gland and has an antimicrobial spectrum different from lysozyme. Microbes and Infection. 10(1), 69-78 PRATOOMSOOT, C., TANIOKA, H., HORI, K., KAWASAKI, S., KINOSHITA, S., TIGHE, P.J., DUA, H., SHAKESHEFF, K.M. and ROSE, F.R.A.J., 2008. A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair Biomaterials. 29(3), 272-281 TODD, I., RADFORD, P.M., DAFFA, N., BAINBRIDGE, S.E., POWELL, R.J. and TIGHE, P.J., 2007. Mutant tumor necrosis factor receptor associated with tumor necrosis factor receptor-associated periodic syndrome is altered antigenically and is retained within patients' leukocytes Arthritis and Rheumatism. 56(8), 2765-2773 PRATOOMSOOT, C., TANIOKA, H., HORI, K., KAWASAKI, S., KINOSHITA, S., TIGHE, P.J., DUA, H., SHAKESHEFF, K.M. and ROSE, F.R.A.J., 2007. A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair Biomaterials. 29(3), 272-281 TODD, I., RADFORD, P.M., ZIEGLER-HEITBROCK, L., GHAEMMAGHAMI, A., POWELL R.J and TIGHE, P.J., 2007. Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome. Arthritis and Rheumatism. 56(12), 4182-4188 REBELO, S.L., BAINBRIDGE, S.E., AMEL-KASHIPAZ, M.R., RADFORD, P.M., POWELL, R.J., TODD, I. and TIGHE, P.J., 2006. Modelling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function Arthritis and Rheumatism. 54(8), 2674-2687 HOPKINSON, A., MCINTOSH, R.S., SHANMUGANATHAN, V., TIGHE, P.J. and DUA, H.S., 2006. Proteomic analysis of amniotic membrane prepared for human transplantation: characterization of proteins and clinical implications Journal of Proteome Research. 5(9), 2226-2235 GINTY, P.J., HOWARD, D., ROSE, F.R.A.J., WHITAKER, M.J., BARRY, J.J.A., TIGHE, P., MUTCH, S.R., SERHATKULU, G., OREFFO, R.O.C., HOWDLE, S.M. and SHAKESHEFF, K.M., 2006. Mammalian cell survival and processing in supercritical CO2 Proceedings of the National Academy of Sciences of the United States of America. 103(19), 7426-7431 NOWLAN, M.L., DREWE, E., BULSARA, H., ESPOSITO, N., ROBINS, R.A., TIGHE, P.J., POWELL, R.J. and TODD, I., 2006. Systemic cytokine levels and the effects of etanercept in TNF receptor-associated periodic syndrome (TRAPS) involving a C33Y mutation in TNFRSF1A Rheumatology. 45(1), 31-37 HOPKINSON, A., MCINTOSH, R.S., TIGHE, P.J., JAMES, D.K. and DUA, H.S., 2006. Amniotic membrane for ocular surface reconstruction: donor variations and effect of handling on TGF-β content Investigative Ophthalmology and Visual Science. 47(10), 4316-4322 MCINTOSH, R.S., CADE, J.E., AL-ABED, M., SHANMUGANATHAN, V., GUPTA, R., BHAN, A., TIGHE, P.J. and DUA, H.S., 2005. The spectrum of antimicrobial peptide expression at the ocular surface Investigative Ophthalmology and Visual Science. 46(4), 1379-1385 HOPKINSON, A., MCINTOSH, R.S., LAYFIELD, R., KEYTE, J., DUA, H.S. and TIGHE, P.J., 2005. Optimised two-dimensional electrophoresis procedures for the protein characterisation of structural tissues Proteomics. 5(7), 1967-1979 CONSTANTINESCU, C.S., TANI, M., RANSOHOFF, R.M., WYSOCKA, M., HILLIARD, B., FUJIOKA, T., MURPHY, S., TIGHE, P.J., SARMA, J.D., TRINCHIERI, G. and ROSTAMI, A., 2005. Astrocytes as antigen-presenting cells: expression of IL-12/IL-23 Journal of Neurochemistry. 95(2), 331-340 MCCLURE, C.P., TIGHE, P.J., ROBINS, R.A., BANSAL, D., BOWMAN, C.A. and KINGSTON, M. BALL, J. K., 2005. HIV coreceptor and chemokine ligand gene expression in the male urethra and female cervix AIDS. 19(12), 1257-1265 TODD, I., RADFORD, P.M., DRAPER-MORGAN, K-A., MCINTOSH, R., BAINBRIDGE, S., DICKINSON, P., JAMHAWI, L., SANSARIDIS, M., HUGGINS, M.L., TIGHE, P.J. and POWELL. R.J., 2004. Mutant forms of tumour necrosis factor receptor I that occur in TNF-receptor-associated periodic syndrome retain signalling functions but show abnormal behaviour Immunology. 113(1), 65-79 HUGGINS, M.L., RADFORD, P.M., MCINTOSH, R.S., BAINBRIDGE, S.E., DICKINSON, P., DRAPER-MORGAN, K-A., TIGHE, P.J., POWELL, R.J. and TODD, I., 2004. Shedding of mutant tumor necrosis factor receptor superfamily 1A associated with tumor necrosis factor receptor-associated periodic syndrome: Differences between cell types Arthritis and Rheumatism. 50(8), 2651-2659 EL GHRABLY, I., POWE, D.G., ORR, G., FISCHER, D., MCINTOSH, R., DUA, H.S. and TIGHE, P.J., 2004. Apoptosis in proliferative vitreoretinopathy Investigative Ophthalmology and Visual Science. 45(5), 1473-9 DROMEY, J. A., WEENINK, S. M., PETERS, G. H., ENDL, J., TIGHE, P. J., TODD, I. and CHRISTIE, M. R., 2004. Mapping of Epitopes for Autoantibodies to the Type 1 Diabetes Autoantigen IA-2 by Peptide Phage Display and Molecular Modeling: Overlap of Antibody and T Cell Determinants The Journal of Immunology. VOL 172(PART 7), 4084-4090
MYRA,C., SLOPER,L., TIGHE,P.J., MCINTOSH,R.S., STEVENS,S.E., GREGSON,R.H.S., SOKAL,M., HAYNES,A.P. and POWELL,R.J., 2004. Treatment of Erdheim-Chester disease with cladribine: a rational approach. British Journal of Ophthalmology. 88(6), 844-847 JOSEPH, ANNIE, HOSSAIN, PARWEZ, JHAM, SEEMA, JONES, RHODRI E, TIGHE, PADDY, MCINTOSH, RICHARD S and DUA, HARMINDER S, 2003. Expression of CD34 and L-selectin on human corneal keratocytes. Investigative Ophthalmology and Visual Science. 44(11), 4689-92 MCKAIG, B.C., HUGHES, K., TIGHE, P.J. and MAHIDA, Y.R., 2002. Differential expression of TGF-β isoforms by normal and inflammatory bowel disease intestinal myofibroblasts American Journal of Physiology: Cell Physiology. 282(1), C172-C182 TIGHE, P.J., STEVENS, S.E., DEMPSEY, S., LE DEIST, F., RIEUX-LAUCAT, F. and EDGAR, J.D.M., 2002. Inactivation of the Fas gene by Alu insertion: retrotransposition in an intron causing splicing variation and autoimmune lymphoproliferative syndrome Genes and Immunity. 3(Supplement 1), S66-S70 AL-BUKHARI, T.A.M.A., RADFORD, P.M., BOURAS, G., DAVENPORT, C., TRIGWELL, S.M., BOTTAZZO, G.-F., LAI, M., SCHWARTZ, H.L., TIGHE, P.J. and TODD, I., 2002. Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): implications for autoantigen modification during pathogenesis Clinical and Experimental Immunology. 130(1), 131-139 MORGAN, J. P., ROBINS, R. A., DUA, H. S. and TIGHE, P. J., 2002. S antigen specific effector T cell activation detected by cytokine flow cytometry British Journal of Ophthalmology. VOL 86(PART 5), 517-520 GRABOWSKA, A.M., LECHNER, F., KLENERMAN, P., TIGHE, P.J., RYDER, S., BALL, J.K., THOMSON, B.J., IRVING, W.L. and ROBINS, R.A., 2001. Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection European Journal of Immunology. 31(8), 2388-2394 WELLS, D.B., TIGHE, P.J., WOOLDRIDGE, K.G., ROBINSON, K. and ALA'ALDEEN, D.A.A., 2001. Differential gene expression during meningeal-meningococcal interaction: evidence for self-defense and early release of cytokines and chemokines Infection and Immunity. 69(4), 2718-2722 WILSON, Z.A., MORROLL, S.M., DAWSON, J., SWARUP, R. and TIGHE, P.J., 2001. The Arabidopsis MALE STERILITY1 (MS1) gene is a transcriptional regulator of male gametogenesis, with homology to the PHD-finger family of transcription factors Plant Journal. 28(1), 27-39 SIMON, A., VAN DEUREN, M., TIGHE, P. J., VAN DER MEER, J. W. M. and DRENTH, J. P. H., 2001. Genetic Analysis as a Valuable Key to Diagnosis and Treatment of Periodic Fever Archives of Internal Medicine. VOL 161(PART 20), 2491-2496 MCINTOSH, R. S., HUGGINS, M. L., KONTOGIANNIS, V., TIGHE, P. J. and POWELL, R. J., 2001. Retroviral activity in Behcet's syndrome and systemic lupus erythematosus detected by a PCR-based reverse transcriptase assay Rheumatology International. VOL 21(PART 2), 53-57 EL-GHRABLY, I A, DUA, H S, ORR, G M, FISCHER, D and TIGHE, P J, 2001. Intravitreal invading cells contribute to vitreal cytokine milieu in proliferative vitreoretinopathy. British Journal of Ophthalmology. 85(4), 461-70 HAYNES, R. J., MCELVEEN, J. E., DUA, H. S., TIGHE, P. J. and LIVERSIDGE, J., 2000. Expression of Human Beta-Defensins in Intraocular Tissues Investigative Ophthalmology and Visual Science. VOL 41(PART 10), 3026-3031
EL-SHERIF, A. M., SETH, R., TIGHE, P. J. and JENKINS, D., 2000. Decreased synthesis and expression of TGF-beta1, beta2 and beta3 in epithelium of HPV 16-positive cervical precancer: a study by microdissection, quantitative RT-PCR, and immunocytochemistry Journal of Pathology. VOL 192(PART 4), 494-501 FURMONAVICIENE, R., TIGHE, P.J., CLARK, M.R., SEWELL, H.F. and SHAKIB, F., 1999. The use of phage-peptide libraries to define the epitope specificity of a mouse monoclonal anti-Der p 1 antibody representative of a major component of the human immunoglobulin E anti-Der p 1 response Clinical and Experimental Allergy. VOL 29(NUMBER 11), 1563-1571 TIGHE, P.J, POWELL-RICHARDS, A., SEWELL, H.F., FISCHER, D., DONOSO, L. and DUA, H.S., 1999. Epitope discovery using bacteriophage display: the minimum epitope of an anti-IRBP antibody. Experimental Eye Research. 68(6), 679-84 HAYNES, R J, TIGHE, P J and DUA, H S, 1999. Antimicrobial defensin peptides of the human ocular surface. British Journal of Ophthalmology. 83(6), 737-41 HAYNES, R. J., TIGHE, P. J., SCOTT, R. A. H. and DUA, H. S., 1999. Human Conjunctiva Contains High Endothelial Venules That Express Lymphocyte Homing Receptors Experimental Eye Research. VOL 69(NUMBER 4), 397-404 EL-GHRABLY, I. A., DUA, H. S., ORR, G. M., FISCHER, D. and TIGHE, P. J., 1999. Detection of cytokine mRNA production in infiltrating cells in proliferative vitreoretinopathy using reverse transcription polymerase chain reaction British Journal of Ophthalmology. VOL 83(NUMBER 11), 1296-1299 HUGGINS, M. L., TODD, I., CAVERS, M. A., PAVULURI, S. R., TIGHE, P. J. and POWELL, R. J., 1999. Antibodies from systemic lupus erythematosus (SLE) sera define differential release of autoantigens from cell lines undergoing apoptosis Clinical and Experimental Immunology. VOL 118(NUMBER 2), 322-328 HAYNES, R J, TIGHE, P J and DUA, H S, 1998. Innate defence of the eye by antimicrobial defensin peptides. Lancet. 352(9126), 451-2 TIGHE, P.J., POWELL-RICHARDS, A, FRANKEL, T, SEWELL, HF, DONOSO, L and DUA, HS, 1996. Determination Of the Epitope Requirements Of an Anti-IRBP Monoclonal- Antibody Investigative Ophthalmology and Visual Science. 37(3), 2474-2474
TIGHE,P.J. and STEVENS,S., 1996. T-cell expansions in the vitreous infiltrate and subretinal exudate in autoimmune uveoretinitis(abstract Bb307) Immunology. 89(suppl 1), 80
TIGHE, P J, LIVERSIDGE, J, FORRESTER, J V and SEWELL, H F, 1995. Analysis of the T-cell receptor beta chain repertoire expressed in endogenous posterior uveitis. Annals of the New York Academy of Sciences. 756, 421-3 COUTINHO, H B, SEWELL, H F, TIGHE, P, KING, G, NOGUEIRA, J C, ROBALINHO, T I, COUTINHO, V B and CAVALCANTI, V M, 1995. Immunocytochemical study of the ontogeny of the marsupial Didelphis albiventris immune system. Journal of Anatomy. 187 ( Pt 1), 37-46
TIGHE, P.J., FORRESTER, J.V., LIVERSIDGE, J. and SEWELL, H.F., 1995. Peripheral CD25 positive T lymphocytes with biased T cell receptor Vß gene usage in autoimmune endogenous posterior uveitis Journal of Clinical Pathology: Molecular Pathology. 48, M46-M50
LAING,, TIGHE,, KWIATKOWSKI,, MILLIGAN,, PRICE, and SEWELL,, 1995. Selection of peptide ligands for the antimucin core antibody C595 using phage display technology: definition of candidate epitopes for a cancer vaccine. Clinical molecular pathology. 48(3), M136-M141
TIGHE, P. J., GOYAL, P. K., WILSON, Z. A. and WAKELIN, D., 1994. Analysis of genetic variation in isolates of Trichinella using random amplified polymorphic DNA MOLECULAR AND BIOCHEMICAL PARASITOLOGY. VOL 63(NUMBER 1), 175 QUINNELL, R. J., SLATER, A. F. G., TIGHE, P. and WALSH, E. A., 1994. Low rate of reinfection with Enterobius vermicularis in a Papua New Guinea village TRANSACTIONS- ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. VOL 88(NUMBER 1), 44 QUINNELL, R J, SLATER, A F, TIGHE, P, WALSH, E A, KEYMER, A E and PRITCHARD, D I, 1993. Reinfection with hookworm after chemotherapy in Papua New Guinea. Parasitology (Cambridge). 106 ( Pt 4), 379-85
DAWSON, S P, WILDE, C J, TIGHE, P J and MAYER, R J, 1993. Characterization of two novel casein transcripts in rabbit mammary gland. Biochemical Journal. 296 ( Pt 3), 777-84