GILBERT J, PEARCY N, NORMAN R, MILLAT, T, WINZER K, KING J, MINTON NP and TWYCROSS J, 2019. Gsmodutils: A python based framework for test-driven genome scale metabolic model development. Bioinformatics. 35, 3397–3403 ANNAN FJ, AL-SINAWI B, HUMPHREYS CM, NORMAN R, WINZER K, KÖPKE M, SIMPSON SD, MINTON NP and HENSTRA AM, 2019. Engineering of vitamin prototrophy in Clostridium ljungdahlii and Clostridium autoethanogenum. Applied Microbiology and Biotechnology. 103, 4633-4648 ARENAS-LÓPEZ C, LOCKER J, OROL D, WALTER F, BUSCHE T, KALINOWSKI J, MINTON NP, KOVÁCS K and WINZER K, 2019. The genetic basis of 3-hydroxypropanoate metabolism in Cupriavidus necator H16. Biotechnology for Biofuels. 12, 150 PANDER B, HARRIS G, SCOTT DJ, WINZER K, KÖPKE M, SIMPSON SD, MINTON NP and HENSTRA AM, 2019. The carbonic anhydrase of Clostridium autoethanogenum represents a new subclass of β-carbonic anhydrases. Applied Microbiology and Biotechnology. 103, 7275-7286 WOODS C, HUMPHREYS CM, RODRIGUES RM, INGLE P, ROWE P, HENSTRA AM, KÖPKE M, SIMPSON SD, WINZER K and MINTON NP, 2019. A Novel Conjugal Donor Strain for Improved DNA transfer into Clostridium spp. Anaerobe. 59, 184-191 LITTLE GT, EHSAAN M, ARENAS-LÓPEZ C, JAWED K, WINZER K, KOVÁCS K and MINTON NP, 2019. Complete Genome Sequence of Cupriavidus necator H16 (DSM 428) Microbiology Resource Announcements. 8, e00814-19 HANKO, ERIK K. R., MINTON, NIGEL P. and MALYS, NAGLIS, 2019. Design, cloning and characterization of transcription factor-based inducible gene expression systems CHEMICAL AND SYNTHETIC BIOLOGY APPROACHES TO UNDERSTAND CELLULAR FUNCTIONS - PT A. 621, 153-169 INGLE, PATRICK, GROOTHUIS, DAPHNE, ROWE, PETER, HUANG, HE, COCKAYNE, ALAN, KUEHNE, SARAH A., JIANG, WEIHONG, GU, YANG, HUMPHREYS, CHRISTOPHER M. and MINTON, NIGEL P., 2019. Generation of a fully erythromycin-sensitive strain of Clostridioides difficile using a novel CRISPR-Cas9 genome editing system SCIENTIFIC REPORTS. 9, SHERIDAN, PAUL O, MARTIN, JENNIFER C, MINTON, NIGEL P, FLINT, HARRY J, O'TOOLE, PAUL W and SCOTT, KAREN P, 2019. Heterologous gene expression in the human gut bacteria Eubacterium rectale and Roseburia inulinivorans by means of conjugative plasmids. Anaerobe. 59, 131-140
GILBERT, JAMES, PEARCY, NICOLE, NORMAN, RUPERT, MILLAT, THOMAS, WINZER, KLAUS, KING, JOHN, HODGMAN, CHARLIE, MINTON, NIGEL and TWYCROSS, JAMIE, 2019. Gsmodutils: a python based framework for test-driven genome scale metabolic model development BIOINFORMATICS. 35(18), 3397-3403 BASHIR, ZEENAT, SHENG, LILI, ANIL, ANNAMMA, LALI, ARVIND, MINTON, NIGEL P. and ZHANG, YING, 2019. Engineering Geobacillus thermoglucosidasius for direct utilisation of holocellulose from wheat straw BIOTECHNOLOGY FOR BIOFUELS. 12(1), BILVERSTONE, T W, MINTON, N P and KUEHNE, S A, 2019. Phosphorylation and functionality of CdtR in Clostridium difficile. Anaerobe. 58, 103-109
SARMA, SHYAMALI, ORTEGA, DAVID, MINTON, NIGEL P., DUBEY, VIKASH KUMAR and MOHOLKAR, VIJAYANAND S., 2019. Homologous overexpression of hydrogenase and glycerol dehydrogenase in Clostridium pasteurianum to enhance hydrogen production from crude glycerol BIORESOURCE TECHNOLOGY. 284, 168-177 CANADAS, INES C., GROOTHUIS, DAPHNE, ZYGOUROPOULOU, MARIA, RODRIGUES, RAQUEL and MINTON, NIGEL P., 2019. RiboCas: A Universal CRISPR-Based Editing Tool for Clostridium ACS SYNTHETIC BIOLOGY. 8(6), 1379-1390 LI, QI, SEYS, FRANCOIS M., MINTON, NIGEL P., YANG, JUNJIE, JIANG, YU, JIANG, WEIHONG and YANG, SHENG, 2019. CRISPR-Cas9(D10A) nickase-assisted base editing in the solvent producer Clostridium beijerinckii BIOTECHNOLOGY AND BIOENGINEERING. 116(6), 1475-1483 DE TISSERA, SASHINI, KOPKE, MICHAEL, SIMPSON, SEAN D., HUMPHREYS, CHRISTOPHER, MINTON, NIGEL P. and DUERRE, PETER, 2019. Syngas Biorefinery and Syngas Utilization BIOREFINERIES. 166, 247-280 SCHATSCHNEIDER, S., ABDELRAZIG, S., SAFO, L., HENSTRA, A. M., MILLAT, T., KIM, D.-H., WINZER, K., MINTON, N. P. and BARRETT, D. A., 2018. Quantitative Isotope-Dilution High-Resolution-Mass-Spectrometry Analysis of Multiple Intracellular Metabolites in Clostridium autoethanogenum with Uniformly 13C-Labeled Standards Derived from Spirulina Analytical Chemistry. 90(7), 4470–4477 NORMAN ROJ, MILLAT T, WINZER K, MINTON N and HODGMAN C, 2018. Progress towards platform chemical production using Clostridium autoethanogenum. Biochemical Society Transactions. 46(3), 523-535 ALAGESAN S, MALYS N, HANKO EKR, EHSAAN M, WINZER K and MINTON NP, 2018. Functional genetic elements for controlling gene expression in Cupriavidus necator H16. Appl Environ Microbiol. 84, e00878-18 HANKO EKR, MINTON NP and MALYS N, 2018. A Transcription Factor-Based Biosensor for Detection of Itaconic Acid. ACS synthetic biology. 7(5), 1436-1446 SCHOELMERICH, MARIE CHARLOTTE, KATSYV, ALEXANDER, SUNG, WOUNG, MIJIC, VANESSA, WIECHMANN, ANJA, KOTTENHAHN, PATRICK, BAKER, JONATHAN, MINTON, NIGEL PETER and MUELLER, VOLKER, 2018. Regulation of lactate metabolism in the acetogenic bacterium Acetobacterium woodii ENVIRONMENTAL MICROBIOLOGY. 20(12), 4587-4595 WESTPHAL, LARS, WIECHMANN, ANJA, BAKER, JONATHAN, MINTON, NIGEL P. and MUELLER, VOLKER, 2018. The Rnf Complex Is an Energy-Coupled Transhydrogenase Essential To Reversibly Link Cellular NADH and Ferredoxin Pools in the Acetogen Acetobacterium woodii JOURNAL OF BACTERIOLOGY. 200(21), HUMPHREYS, CHRISTOPHER M. and MINTON, NIGEL P., 2018. Advances in metabolic engineering in the microbial production of fuels and chemicals from C1 gas CURRENT OPINION IN BIOTECHNOLOGY. 50, 174-181 KUEHNE, SARAH A., DEMPSTER, ANDREW W., COLLERY, MARK M., JOSHI, NIMITRAY, JOWETT, JAMIE, KELLY, MICHELLE L., CAVE, RORY, LONGSHAW, CHRIS M. and MINTON, NIGEL P., 2018. Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 73(4), 973-980 PAPATHEODOROU, PANAGIOTIS, BARTH, HOLGER, MINTON, NIGEL and AKTORIES, KLAUS, 2018. Cellular Uptake and Mode-of-Action of Clostridium difficile Toxins UPDATES ON CLOSTRIDIUM DIFFICILE IN EUROPE: ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH, VOL 8. 1050, 77-96 ALVAREZ, R., INOSTROZA, O., GARAVAGLIA, M., MINTON, N. P., PAREDES-SABJA, D. and GIL, F., 2018. Effect of antibiotic treatment on the formation of non-spore Clostridium difficile persister-like cells JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 73(9), 2396-2399 SCHWARZ KM, GROSSE-HONEBRINK A, DERECKA K, ROTTA C, ZHANG Y and MINTON NP, 2017. Towards improved butanol production through targeted genetic modification of Clostridium pasteurianum. Metabolic engineering. 40, 124-137 STUDER N, DESHARNAIS L, BEUTLER M, BRUGIROUX S, TERRAZOS MA, MENIN L, SCHÜRCH CM, MCCOY KD, KUEHNE SA, MINTON NP, STECHER B, BERNIER-LATMANI R and HAPFELMEIER S, 2017. Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model. Frontiers in cellular and infection microbiology. 6, 191 LIEW F, HENSTRA AM, KӦPKE M, WINZER K, SIMPSON SD and MINTON NP, 2017. Metabolic engineering of Clostridium autoethanogenum for selective alcohol production. Metabolic Engineering. 40, 104-114 POEHLEIN A, MONTOYA SOLANO JD, FLITSCH SK, KRABBEN P, WINZER K, REID SJ, JONES DT, GREEN E, MINTON NP, DANIEL R and DÜRRE P, 2017. Microbial solvent formation revisited by comparative genome analysis. Biotechnology for Biofuels. 10, 58 MOWDAY, ALEXANDRA M., GUISE, CHRIS P., KUBIAK, ALEKSANDRA M., MINTON, NIGEL P., ABBATTISTA, MARIA R., LAMBIN, PHILIPPE, SMAILL, JEFF B., DUBOIS, LUDWIG J., THEYS, JAN and PATTERSON, ADAM V., 2017. Efficacy of a Novel Enzyme/Prodrug Combination for Clostridia Directed Enzyme Prodrug Therapy MOLECULAR THERAPY. 25(5), 131-132
ZYGOUROPOULOU, MARIA, KUBIAK, ALEKSANDRA M., COPP, JANINE N., DUBOIS, LUDWIG J., MOWDAY, ALEXANDRA M., GUISE, CHRIS P., ACKERLEY, DAVID, LAMBIN, PHILIPPE, SMAILL, JEFF B., PATTERSON, ADAM V., MINTON, NIGEL P. and THEYS, JAN, 2017. Clostridium as "Trojan Horse" Vectors for Cancer Treatment MOLECULAR THERAPY. 25(5), 23-23
JAIN, S, SMYTH, D, O'HAGAN, B.M.G, HEAP, J.T, MCMULLAN, G, MINTON, N.P and TERNAN, N.G, 2017. Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability Scientific Reports. 7(1), 17522 GREEN. E, MINTON, N and HEEG, D, 2017. Making clostridia great again Industrial Biotechnology. 13(2), 52-56 ORTEGA, P, SCHUCHMANN, K, MINTON, N and ZHANG, Y, 2017. Co-production of platform chemicals 1, 3 propane diol and 3-hydroxy propionic acid from waste glycerol by clostridium pasteurianum In: Synthetic Biology Conference, SEED 2017: Engineering, Evolution, and Design. 110-111 MEANEY, CAROLYN A., CARTMAN, STEPHEN T., MCCLURE, PETER J. and MINTON, NIGEL P., 2016. The role of small acid-soluble proteins (SASPs) in protection of spores of Clostridium botulinum against nitrous acid INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY. 216, 25-30 BURBIDGE A and MINTON NP, 2016. SBRC-Nottingham: sustainable routes to platform chemicals from C1 waste gases. Biochemical Society transactions. 44(3), 684-6 HUANG H, CHAI C, LI N, ROWE P, MINTON NP, YANG S, JIANG W and GU Y, 2016. CRISPR/Cas9-Based Efficient Genome Editing in Clostridium ljungdahlii, an Autotrophic Gas-Fermenting Bacterium. ACS Synthetic Biology. 5(12), 1355-1361 MINTON NP, EHSAAN M, HUMPHREYS CM, LITTLE GT, BAKER J, HENSTRA AM, LIEW F, KELLY ML, SHENG L and SCHWARZ K, 2016. A roadmap for gene system development in Clostridium. Anaerobe. 41, 104-112. WILLSON BJ, KOVÁCS K, WILDING-STEELE T, MARKUS R, WINZER K and MINTON NP, 2016. Production of a functional cell wall-anchored minicellulosome by recombinant Clostridium acetobutylicum ATCC 824. Biotechnology for Biofuels. 9, 109 LIEW F, HENSTRA AM, WINZER K, KÖPKE M, SIMPSON SD and MINTON NP, 2016. Insights into CO2 Fixation Pathway of Clostridium autoethanogenum by Targeted Mutagenesis. mBio. 7(3), e1700711 LI Q, CHEN J, MINTON NP, ZHANG Y, WEN Z, LIU J, YANG H, ZENG Z, REN X, YANG J, GU Y, JIANG W, JIANG Y and YANG S, 2016. CRISPR-based genome editing and expression control systems in Clostridium acetobutylicum and Clostridium beijerinckii. Biotechnology Journal. 11(7), 961-72 WALKER DJ, HEAP JT, WINZER K and MINTON NP, 2016. A genetic assay for gene essentiality in Clostridium. Anaerobe. 42, 40-43 COWARDIN CA, BUONOMO EL, SALEH MM, WILSON MG, BURGESS SL, KUEHNE SA, SCHWAN C, EICHHOFF AM, KOCH-NOLTE F, LYRAS D, AKTORIES K, MINTON NP and PETRI WA, 2016. The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia. Nature microbiology. 1(8), 16108 STEVENSON EC, MAJOR GA, SPILLER RC, KUEHNE SA and MINTON NP, 2016. Co-infection and emergence of rifamycin resistance during a recurrent Clostridium difficile infection. Journal of clinical microbiology. 54(11), 2689-2694 (In Press.)
EHSAAN M, KUEHNE SA and MINTON NP, 2016. Clostridium difficile Genome Editing Using pyrE Alleles. Methods in molecular biology (Clifton, N.J.). 1476, 35-52 MOWDAY AM, GUISE CP, ACKERLEY DF, MINTON NP, LAMBIN P, DUBOIS LJ, THEYS J, SMAILL JB and PATTERSON AV, 2016. Advancing Clostridia to Clinical Trial: Past Lessons and Recent Progress. Cancers. 8(7), WEN Z, MINTON NP, ZHANG Y, LI Q, LIU J, JIANG Y and YANG S, 2016. Enhanced solvent production by metabolic engineering of a twin-clostridial consortium. Metabolic engineering. 39, 38-48 STEVENSON E, MINTON NP and KUEHNE SA, 2015. The role of flagella in Clostridium difficile pathogenicity. Trends in microbiology. HUMPHREYS, CHRISTOPHER M., MCLEAN, SAMANTHA, SCHATSCHNEIDER, SARAH, MILLAT, THOMAS, HENSTRA, ANNE M., ANNAN, FLORENCE J., BREITKOPF, RONJA, PANDER, BART, PIATEK, PAWEL, ROWE, PETER, WICHLACZ, ALEXANDER T., WOODS, CRAIG, NORMAN, RUPERT, BLOM, JOCHEN, GOESMAN, ALEXANDER, HODGMAN, CHARLIE, BARRETT, DAVID, THOMAS, NEIL R., WINZER, KLAUS and MINTON, NIGEL P., 2015. Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium BMC GENOMICS. 16, HENSBERGEN, PAUL J., KLYCHNIKOV, OLEG I., BAKKER, DENNIS, DRAGAN, IRINA, KELLY, MICHELLE L., MINTON, NIGEL P., CORVER, JEROEN, KUIJPER, ED J., DRIJFHOUT, JAN WOUTER and VAN LEEUWEN, HANS C., 2015. Clostridium difficile secreted Pro-Pro endopeptidase PPEP-1 (ZMP1/CD2830) modulates adhesion through cleavage of the collagen binding protein CD2831 FEBS LETTERS. 589(24), 3952-3958 WALTER, BEATA M., CARTMAN, STEPHEN T., MINTON, NIGEL P., BUTALA, MATEJ and RUPNIK, MAJA, 2015. The SOS Response Master Regulator LexA Is Associated with Sporulation, Motility and Biofilm Formation in Clostridium difficile PLOS ONE. 10(12), KUBIAK, ALEKSANDRA M. and MINTON, NIGEL P., 2015. The potential of clostridial spores as therapeutic delivery vehicles in tumour therapy RESEARCH IN MICROBIOLOGY. 166(4), 244-254 LITTLE, GARETH T, WINZER, KLAUS and MINTON, NIGEL P, 2015. Genome Sequence of the Solvent-Producing Clostridium beijerinckii Strain 59B, Isolated from Staffordshire Garden Soil. Genome announcements. 3(2),
ROTTA, CARLO, POEHLEIN, ANJA, SCHWARZ, KATRIN, MCCLURE, PETER, DANIEL, ROLF and MINTON, NIGEL P, 2015. Closed Genome Sequence of Clostridium pasteurianum ATCC 6013. Genome announcements. 3(1),
KUBIAK, ALEKSANDRA M, POEHLEIN, ANJA, BUDD, PATRICK, KUEHNE, SARAH A, WINZER, KLAUS, THEYS, JAN, LAMBIN, PHILIP, DANIEL, ROLF and MINTON, NIGEL P, 2015. Complete Genome Sequence of the Nonpathogenic Soil-Dwelling Bacterium Clostridium sporogenes Strain NCIMB 10696. Genome announcements. 3(4), BARKETI-KLAI A, MONOT M, HOYS S, LAMBERT-BORDES S, KUEHNE SA, MINTON N, COLLIGNON A, DUPUY B and KANSAU I, 2014. The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection. PloS One. 9(5), e96876 HEAP JT, THEYS J, EHSAAN M, KUBIAK AM, DUBOIS L, PAESMANS K, MELLAERT LV, KNOX R, KUEHNE SA, LAMBIN P and MINTON NP, 2014. Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. Oncotarget. 5(7), 1761-9 KOVACS-SIMON A, LEUZZI R, KASENDRA M, MINTON N, TITBALL RW and MICHELL SL, 2014. Lipoprotein CD0873 is a novel adhesin of Clostridium difficile. The Journal of infectious diseases. 210(2), 274-84 WASELS F, KUEHNE SA, CARTMAN ST, SPIGAGLIA P, BARBANTI F, MINTON NP and MASTRANTONIO P, 2014. Fluoroquinolone resistance does not impose a cost on the fitness of Clostridium difficile in vitro. Antimicrobial agents and chemotherapy. CARTMAN S.T., HEAP J.T., KUEHNE S., COOKSLEY C.M., EHSAAN M., WINZER K. and MINTON N.P., 2014. Clostridial Gene Tools. In: Systems Biology of Clostridium Imperial College Press. 21-55 MILLAT, THOMAS, VOIGT, CHRISTINE, JANSSEN, HOLGER, COOKSLEY, CLARE M., WINZER, KLAUS, MINTON, NIGEL P., BAHL, HUBERT, FISCHER, RALF-JOERG and WOLKENHAUER, OLAF, 2014. Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum-evidence from a mathematical model APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 98(21), 9059-9072 DAHLSTEN, ELIAS, ZHANG, ZHEN, SOMERVUO, PANU, MINTON, NIGEL P., LINDSTROM, MIIA and KORKEALA, HANNU, 2014. The Cold-Induced Two-Component System CBO0366/CBO0365 Regulates Metabolic Pathways with Novel Roles in Group I Clostridium botulinum ATCC 3502 Cold Tolerance APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 80(1), 306-319 KUEHNE, SARAH A., COLLERY, MARK M., KELLY, MICHELLE L., CARTMAN, STEPHEN T., COCKAYNE, ALAN and MINTON, NIGEL P., 2014. Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain JOURNAL OF INFECTIOUS DISEASES. 209(1), 83-86 KAEHLER, S. T., WALSH, N., MINTON, N., GILLEN, D., FREEMAN, J. and BWIRE, R., 2014. Distinguishing Different Study Types, Biomedical Research, Market Research, Non-Interventional Studies and Clinical Trials: A Newly Developed Decision Tree DRUG SAFETY. 37(10), 846-846
ETHAPA T, LEUZZI R, NG YK, BABAN ST, ADAMO R, KUEHNE SA, SCARSELLI M, MINTON NP, SERRUTO D and UNNIKRISHNAN M, 2013. Multiple Factors Modulate Biofilm Formation by the Anaerobic Pathogen Clostridium difficile. Journal of bacteriology. 195(3), 545-55 JABBARI S, STEINER E, HEAP JT, WINZER K, MINTON NP and KING JR, 2013. The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum. Mathematical Biosciences. 243(2), 223-39 DONALD RGK, FLINT M, KALYAN N, JOHNSON E, WITKO SE, KOTASH C, ZHAO P, MEGATI S, YURGELONIS I, LEE PK, MATSUKA YV, SEVERINA E, DEATLY A, SIDHU M, JANSEN KU, MINTON NP and ANDERSON AS, 2013. A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile. Microbiology (Reading, England). 159(Pt 7), 1254-66 JAFARI NV, KUEHNE SA, BRYANT CE, ELAWAD M, WREN BW, MINTON NP, ALLAN E and BAJAJ-ELLIOTT M, 2013. Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s). PloS one. 8(7), e69846 KOVÁCS, K., WILLSON, B.J., SCHWARZ, K., HEAP, J.T., JACKSON, A., BOLAM, D.N., WINZER, K. and MINTON, N.P., 2013. Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824 Biotechnology for Biofuels. 6, 117 BABAN ST, KUEHNE SA, BARKETI-KLAI A, CARTMAN ST, KELLY ML, HARDIE KR, KANSAU I, COLLIGNON A and MINTON NP, 2013. The Role of Flagella in Clostridium difficile Pathogenesis: Comparison between a Non-Epidemic and an Epidemic Strain. PloS one. 8(9), e73026 COLLERY, M.M, GOVIND, R, MINTON, N and KUEHNE, S.A, 2013. Pathogenicity mechanisms of Clostridium difficile. In: TILLOSTON, G.S and WEISS, K, eds., Clostridium Difficile: New Challenges for an Old Foe 1. Future Medicine Ltd.. 21-33 STEINER, E., SCOTT, J., MINTON, N.P. and WINZER, K., 2012. An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum Applied and Environmental Microbiology. 78(4), 1113-1122 OLLING A, SEEHASE S, MINTON NP, TATGE H, SCHRÖTER S, KOHLSCHEEN S, PICH A, JUST I and GERHARD R, 2012. Release Of Tcda And Tcdb From Clostridium Difficile Cdi 630 Is Not Affected By Functional Inactivation Of The Tcde Gene. Microbial Pathogenesis. 52(1), 92-100 HEAP, J.T., EHSAAN, M., COOKSLEY, C.M., NG, Y.-H., CARTMAN, S.T., WINZER, K. and MINTON, N.P., 2012. Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker Nucleic Acids Research. 40(8), e59 COOKSLEY, C.M., ZHANG, Y., WANG, H., REDL, S., WINZER, K. and MINTON, N.P., 2012. Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway Metabolic Engineering. 14(6), 630-641 KUEHNE SA and MINTON NP, 2012. ClosTron-mediated engineering of Clostridium. Bioengineered. 3(4), 247-54 BURNS DA and MINTON NP, 2011. Sporulation Studies In Clostridium Difficile. Journal Of Microbiological Methods. 87(2), 133-8 KUEHNE SA, HEAP JT, COOKSLEY CM, CARTMAN ST and MINTON NP, 2011. Clostron-Mediated Engineering Of Clostridium. Methods In Molecular Biology (Clifton, N.J.). 765, 389-407 DAWSON LF, DONAHUE EH, CARTMAN ST, BARTON RH, BUNDY J, MCNERNEY R, MINTON NP and WREN BW, 2011. The Analysis Of Para-Cresol Production And Tolerance In Clostridium Difficile 027 And 012 Strains. Bmc Microbiology. 11, 86 STEINER, E., DAGO, A.E., YOUNG, D.I., HEAP, J.T., MINTON, N.P., HOCH, J.A. and YOUNG, M., 2011. Multiple orphan histidine kinases interact directly with
Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum Molecular Microbiology. 80(3), 641-654 SÖDERHOLM H, LINDSTRÖM M, SOMERVUO P, HEAP J, MINTON N, LINDÉN J and KORKEALA H, 2011. Cspb Encodes A Major Cold Shock Protein In Clostridium Botulinum Atcc 3502. International Journal Of Food Microbiology. 146(1), 23-30 MINTON, NP and WINZER K, 2011. Solvent production-not to be sniffed at! Biobutanol: 21st century biofuel. Biochemist. 33, 8-13
COOKSLEY, CLARE M, DAVIS, IAN J, WINZER, KLAUS, CHAN, WENG C, PECK, MICHAEL W and MINTON, NIGEL P, 2010. Regulation of neurotoxin production and sporulation by a putative agrBD signaling system in proteolytic Clostridium botulinum. Applied and Environmental Microbiology. 76(13), 4448-60 HEAP, J.T., KUEHNE, S.A., EHSAAN, M., CARTMAN, S.T., COOKSLEY, C.M., SCOTT, J.C. and MINTON, N.P., 2010. The ClosTron: mutagenesis in Clostridium refined and streamlined Journal of Microbiological Methods. 80(1), 49-55 CARTMAN, S.T. AND MINTON N.P., 2010. A mariner-Based Transposon System for In Vivo Random Mutagenesis of Clostridium difficile. Applied and Environmental Microbiology. 76(4), 1103-1109
HEAP, JOHN T, CARTMAN, STEPHEN T, KUEHNE, SARAH A, COOKSLEY, CLARE and MINTON, NIGEL P, 2010. ClosTron-targeted mutagenesis. Methods in molecular biology (Clifton, N.J.). 646, 165-82 BURNS DA, HEAP JT and MINTON NP, 2010. Clostridium Difficile Spore Germination: An Update. Research In Microbiology. 161(9), 730-4 KUEHNE, S.A., CARTMAN, S.T., HEAP, J.T., KELLY, M.L., COCKAYNE, A. and MINTON, N.P., 2010. The role of toxin A and toxin B in Clostridium difficile infection Nature. 467(7316), 711-713 CARTMAN, S.T., HEAP, J.T., KUEHNE, S.A., COCKAYNE, A. and MINTON, N.P., 2010. The emergence of 'hypervirulence' in Clostridium difficile International Journal of Medical Microbiology. 300(6), 387-395 BRADSHAW M, MARSHALL KM, HEAP JT, TEPP WH, MINTON NP and JOHNSON EA, 2010. Construction Of A Nontoxigenic Clostridium Botulinum Strain For Food Challenge Studies. Applied And Environmental Microbiology. 76(2), 387-93 HEAP, J.T, PENNINGTON, O.J and CARTMAN, S.T. AND MINTON, N.P., 2009. A modular system for Clostridium shuttle plasmids. Journal of Microbiological Methods. 78(1), 79-85
ABUKHADER, MAJED M, HEAP, JOHN, DE MATTEIS, CRISTINA I, DOUGHTY, STEPHEN W, MINTON, NIGEL and PAOLI, MAX, 2007. Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 63(Pt 9), 746-50
HEAP, J.T., PENNINGTON, O.J., CARTMAN, S.T., CARTER, G.P. and MINTON, N.P., 2007. The ClosTron: A universal gene knock-out system for the genus Clostridium. Journal of Microbiological Methods. 70(3), 452-464 SEBAIHIA M, PECK MW, MINTON NP, THOMSON NR, HOLDEN MTG, MITCHELL WJ, CARTER AT, BENTLEY SD, MASON DR, CROSSMAN L, PAUL CJ, IVENS A, WELLS-BENNIK MHJ, DAVIS IJ, CERDEÑO-TÁRRAGA AM, CHURCHER C, QUAIL MA, CHILLINGWORTH T, FELTWELL T, FRASER A, GOODHEAD I, HANCE Z, JAGELS K, LARKE N, MADDISON M, MOULE S, MUNGALL K, NORBERTCZAK H, RABBINOWITSCH E, SANDERS M, SIMMONDS M, WHITE B, WHITHEAD S and PARKHILL J, 2007. Genome Sequence Of A Proteolytic (Group I) Clostridium Botulinum Strain Hall A And Comparative Analysis Of The Clostridial Genomes. Genome Research. 17(7), 1082-92 CHAUDHURI RR, REN C, DESMOND L, VINCENT GA, SILMAN NJ, BREHM JK, ELMORE MJ, HUDSON MJ, FORSMAN M, ISHERWOOD KE, GURYCOVÁ D, MINTON NP, TITBALL RW, PALLEN MJ and VIPOND R, 2007. Genome Sequencing Shows That European Isolates Of Francisella Tularensis Subspecies Tularensis Are Almost Identical To Us Laboratory Strain Schu S4. Plos One. 2(4), e352 THEYS, J., PENNINGTON, O., DUBOIS, L., ANLEZARK, G., VAUGHAN, T., MENGESHA, A., LANDUYT, W., ANNÉ, J., BURKE, P.J., DÛRRE, P., WOUTERS, B.G., MINTON, N.P. and LAMBIN, P., 2006. Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo. British Journal of Cancer. 95(9), 1212-1219 SEBAIHIA M, WREN BW, MULLANY P, FAIRWEATHER NF, MINTON N, STABLER R, THOMSON NR, ROBERTS AP, CERDEÑO-TÁRRAGA AM, WANG H, HOLDEN MTG, WRIGHT A, CHURCHER C, QUAIL MA, BAKER S, BASON N, BROOKS K, CHILLINGWORTH T, CRONIN A, DAVIS P, DOWD L, FRASER A, FELTWELL T, HANCE Z, HOLROYD S, JAGELS K, MOULE S, MUNGALL K, PRICE C, RABBINOWITSCH E, SHARP S, SIMMONDS M, STEVENS K, UNWIN L, WHITHEAD S, DUPUY B, DOUGAN G, BARRELL B and PARKHILL J, 2006. The Multidrug-Resistant Human Pathogen Clostridium Difficile Has A Highly Mobile, Mosaic Genome. Nature Genetics. 38(7), 779-86 VIPOND J, VIPOND R, ALLEN-VERCOE E, CLARK SO, HATCH GJ, GOOCH KE, BACON J, HAMPSHIRE T, SHUTTLEWORTH H, MINTON NP, BLAKE K, WILLIAMS A and MARSH PD, 2006. Selection Of Novel Tb Vaccine Candidates And Their Evaluation As Dna Vaccines Against Aerosol Challenge. Vaccine. 24(37-39), 6340-50 KUIJPER, E. J., COIGNARD, B. and TULL, P., 2006. Emergence of Clostridium difficile-associated disease in North America and Europe CLINICAL MICROBIOLOGY AND INFECTION. 12, 2-18 CARTER, G.P., PURDY, D., WILLIAMS, P. and MINTON, N.P., 2005. Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling system Journal of Medical Microbiology. 54(2), 119-127 ABUKHADER, M., HEAP, J., DE MATTEIS, C., KELLAM, B., DOUGHTY, S.W., MINTON, N. and PAOLI, M., 2005. Binding of the anticancer prodrug CB1954 to the activating enzyme NQ02 revealed by the crystal structure of their complex Journal of Medicinal Chemistry. 48(24), 7714-7719 SHARMA, S. K., PEDLEY, R. B., BHATIA, J., BOXER, G. M., EL-EMIR, E., QURESHI, U., TOLNER, B., LOWE, H., MICHAEL, N. P. and MINTON, N., 2005. Sustained Tumor Regression of Human Colorectal Cancer Xenografts Using a Multifunctional Mannosylated Fusion Protein in Antibody-Directed Enzyme Prodrug Therapy Clinical Cancer Research. VOL 11(NUMB 2), 814-825
SHARMA SK, PEDLEY RB, BHATIA J, BOXER GM, EL-EMIR E, QURESHI U, TOLNER B, LOWE H, MICHAEL NP, MINTON N, BEGENT RHJ and CHESTER KA, 2005. Sustained Tumor Regression Of Human Colorectal Cancer Xenografts Using A Multifunctional Mannosylated Fusion Protein In Antibody-Directed Enzyme Prodrug Therapy. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research. 11(2 Pt 1), 814-25
VAN MELLAERT, LIEVE, THEYS, JAN, PENNINGTON, OLIVER, BARBE, SOFIE, NUYTS, SANDRA, LANDUYT, WILLIAM, LAMBIN, PHILIPPE, MINTON, NIGEL P. and ANNE, JOZEF, 2005. Clostridia as production systems for prokaryotic and eukaryotic proteins of therapeutic value in tumor treatment 877-893
DAVIS, I.J, CARTER, G, YOUNG, M and MINTON, N, 2005. Gene cloning in clostridia. In: DÜRRE, P., ed., Handbook on clostridia 1. CRC Press. 37-52 NIOCHE, P., BERKA, V., VIPOND, J., MINTON, N., TSAI, A.-L. and RAMAN, C.S., 2004. Femtomolar sensitivity of a NO sensor from Clostridium botulinum Science. 306(5701), 1550-1553 MAYER, A, SHARMA, S K, TOLNER, B, MINTON, N P, PURDY, D, AMLOT, P, THARAKAN, G, BEGENT, R H J and CHESTER, K A, 2004. Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT). British Journal of Cancer. 90(12), 2402-10 MINTON, N., CARTER, G., HERBERT, M., O'KEEFFE, T., PURDY, D., ELMORE, M., OSTROWSKI, A., PENNINGTON, O. and DAVIS, I., 2004. The development of Clostridium difficile genetic systems Anaerobe. VOL 10(NUMBER 2), 75-84 HERBERT, M., O'KEEFFE, T. A., PURDY, D., ELMORE, M. and MINTON, N. P., 2003. Gene transfer into Clostridium difficile CD630 and characterisation of its methylase genes FEMS Microbiology Letters. VOL 229(NUMBER 1), 103-110 ROBERTS, A. P., HENNEQUIN, C., ELMORE, M., COLLIGNON, A., KARJALAINEN, T., MINTON, N. and MULLANY, P., 2003. Development of an integrative vector for the expression of antisense RNA in Clostridium difficile Journal of Microbiological Methods. VOL 55(NUMBER 3), 617-624 MINTON NP, 2003. Clostridia In Cancer Therapy. Nature Reviews. Microbiology. 1(3), 237-42 HERBERT M, O'KEEFFE TA, PURDY D, ELMORE M and MINTON NP, 2003. Gene Transfer Into Clostridium Difficile Cd630 And Characterisation Of Its Methylase Genes. Fems Microbiology Letters. 229(1), 103-10 ROBERTS AP, HENNEQUIN C, ELMORE M, COLLIGNON A, KARJALAINEN T, MINTON N and MULLANY P, 2003. Development Of An Integrative Vector For The Expression Of Antisense Rna In Clostridium Difficile. Journal Of Microbiological Methods. 55(3), 617-24 PURDY, D., O' KEEFFE, T.A.T., ELMORE, M., HERBERT, M., MCLEOD, A., BOKORI-BROWN, M., OSTROWSKI, A. and MINTON, N.P., 2002. Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier. Molecular Microbiology. 46(2), 439-452 ANLEZARK, G. M., VAUGHAN, T., FASHOLA-STONE, E., MICHAEL, N. P., MURDOCH, H., SIMS, M. A., STUBBS, S., WIGLEY, S. and MINTON, N. P., 2002. Bacillus amyloliquefaciens orthologue of Bacillus subtilis ywrO encodes a nitroreductase enzyme which activates the prodrug CB 1954 Microbiology. VOL 148(PART 1), 297-306
SPENCER, D. I. R., ROBSON, L., PURDY, D., WHITELEGG, N. R., MICHAEL, N. P., BHATIA, J., SHARMA, S. K., REES, A. R., MINTON, N. P. and BEGENT, R. H. J., 2002. A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics Proteomics. VOL 2(NUMB 3), 271-279 SPENCER DIR, ROBSON L, PURDY D, WHITELEGG NR, MICHAEL NP, BHATIA J, SHARMA SK, REES AR, MINTON NP, BEGENT RHJ and CHESTER KA, 2002. A Strategy For Mapping And Neutralizing Conformational Immunogenic Sites On Protein Therapeutics. Proteomics. 2(3), 271-9 ANLEZARK GM, VAUGHAN T, FASHOLA-STONE E, MICHAEL NP, MURDOCH H, SIMS MA, STUBBS S, WIGLEY S and MINTON NP, 2002. Bacillus Amyloliquefaciens Orthologue Of Bacillus Subtilis Ywro Encodes A Nitroreductase Enzyme Which Activates The Prodrug Cb 1954. Microbiology (Reading, England). 148(Pt 1), 297-306
PURDY D, O'KEEFFE TAT, ELMORE M, HERBERT M, MCLEOD A, BOKORI-BROWN M, OSTROWSKI A and MINTON NP, 2002. Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier. Molecular microbiology. 46(2), 439-52
GODA SK, SHARMAN AF, YATES M, MANN N, CARR N, MINTON NP and BREHM JK, 2000. Recombinant expression analysis of natural and synthetic bovine alpha-casein in Escherichia coli. Applied microbiology and biotechnology. 54(5), 671-6 DAVIS TO, HENDERSON I, BREHM JK and MINTON NP, 2000. Development of a transformation and gene reporter system for group II, non-proteolytic Clostridium botulinum type B strains. Journal of molecular microbiology and biotechnology. 2(1), 59-69
FOX ME, LEMMON MJ, GIACCIA AJ, MINTON NP and BROWN JM, 2000. Genetically modified clostridium for gene therapy of tumors. Methods in molecular medicine. 35, 413-8 JOHNSON AW, MINTON NA, BRENNEMAN TB, BURTON GW, CULBREATH AK, GASCHO GJ and BAKER SH, 1999. Bahiagrass, corn, cotton rotations, and pesticides for managing nematodes, diseases, and insects on peanut. Journal of nematology. 31(2), 191-200
TANGNEY M, BREHM JK, MINTON NP and MITCHELL WJ, 1998. A gene system for glucitol transport and metabolism in Clostridium beijerinckii NCIMB 8052. Applied and environmental microbiology. 64(5), 1612-9
GODA SK, EISSA O, AKHTAR M and MINTON NP, 1997. Molecular analysis of a Clostridium butyricum NCIMB 7423 gene encoding 4-alpha-glucanotransferase and characterization of the recombinant enzyme produced in Escherichia coli. Microbiology (Reading, England). 143 ( Pt 10), 3287-94
LEMMON MJ, VAN ZIJL P, FOX ME, MAUCHLINE ML, GIACCIA AJ, MINTON NP and BROWN JM, 1997. Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment. Gene therapy. 4(8), 791-6 REIZER J, MITCHELL WJ, MINTON N, BREHM J, REIZER A and SAIER MH, 1996. Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum. Current microbiology. 33(5), 331-3 HENDERSON I, WHELAN SM, DAVIS TO and MINTON NP, 1996. Genetic characterisation of the botulinum toxin complex of Clostridium botulinum strain NCTC 2916. FEMS microbiology letters. 140(2-3), 151-8
MICHAEL NP, CHESTER KA, MELTON RG, ROBSON L, NICHOLAS W, BODEN JA, PEDLEY RB, BEGENT RH, SHERWOOD RF and MINTON NP, 1996. In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein. Immunotechnology : an international journal of immunological engineering. 2(1), 47-57
FOX ME, LEMMON MJ, MAUCHLINE ML, DAVIS TO, GIACCIA AJ, MINTON NP and BROWN JM, 1996. Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. Gene therapy. 3(2), 173-8
FOX, M.E, LEMMON, M.J, MAUCHLINE, M.L, DAVIS, T.O, GIACCIA, A.J, MINTON, N.P and BROWN, J.M, 1996. Corrigendum: Anaerobic bacteria as a delivery system for cancer gene therapy: In vitro activation of 5-fluorocytosine by genetically engineered clostridia Gene Therapy. 3(8), 741
BRIDGEWATER JA, SPRINGER CJ, KNOX RJ, MINTON NP, MICHAEL NP and COLLINS MK, 1995. Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954. European journal of cancer (Oxford, England : 1990). 31A(13-14), 2362-70 MINTON NP, MAUCHLINE ML, LEMMON MJ, BREHM JK, FOX M, MICHAEL NP, GIACCIA A and BROWN JM, 1995. Chemotherapeutic tumour targeting using clostridial spores. FEMS microbiology reviews. 17(3), 357-64 MINTON NP, 1995. Molecular genetics of clostridial neurotoxins. Current topics in microbiology and immunology. 195, 161-94
RIXON, JE, SHARP, R, ODONNELL, AG, HAZLEWOOD, GP, BREHM, JK, MINTON, NP and GILBERT, HJ, 1995. HIGH-LEVEL EXPRESSION OF A HETEROLOGOUS PROTEIN IN LACTOBACILLUS-PLANTARUM AND ITS EFFECT ON THE PERSISTENCE OF THE RECOMBINANT STRAIN IN SILAGE BIOTECHNOLOGY LETTERS. 17(6), 561-566 ELMORE, MICHAEL J., HUTSON, ROGER A., COLLINS, MATTHEW D., BODSWORTH, NICOLA J., WHELAN, SARAH M. and MINTON, NIGEL P., 1995. Nucleotide sequence of the gene coding for proteolytic (group I) Clostridium botulinum type F neurotoxin: Genealogical comparison with other clostridial neurotoxins Systematic and Applied Microbiology. 18(1), 23-31
FAULKNER, JDB and MINTON, NP, 1993. RAPID SMALL-SCALE ISOLATION OF MESSENGER-RNA FROM WHOLE YEAST-CELLS BIOTECHNIQUES. 14(5), 718-+
OULTRAM, JD, LOUGHLIN, M, WALMSLEY, R, GUNNERY, SM and MINTON, NP, 1993. THE NUCLEOTIDE-SEQUENCE OF GENES INVOLVED IN THE LEUCINE BIOSYNTHETIC-PATHWAY OF CLOSTRIDIUM-PASTEURIANUM DNA SEQUENCE. 4(2), 105-111 CHAMBERS, SP, BREHM, JK, MICHAEL, NP, ATKINSON, T and MINTON, NP, 1992. PHYSICAL CHARACTERIZATION AND OVER-EXPRESSION OF THE BACILLUS-CALDOTENAX SUPEROXIDE-DISMUTASE GENE FEMS MICROBIOLOGY LETTERS. 91(3), 277-284
WHELAN, SM, ELMORE, MJ, BODSWORTH, NJ, ATKINSON, T and MINTON, NP, 1992. THE COMPLETE AMINO-ACID-SEQUENCE OF THE CLOSTRIDIUM-BOTULINUM TYPE-E NEUROTOXIN, DERIVED BY NUCLEOTIDE-SEQUENCE ANALYSIS OF THE ENCODING GENE EUROPEAN JOURNAL OF BIOCHEMISTRY. 204(2), 657-667 WHELAN, SM, ELMORE, MJ, BODSWORTH, NJ, BREHM, JK, ATKINSON, T and MINTON, NP, 1992. MOLECULAR-CLONING OF THE CLOSTRIDIUM-BOTULINUM STRUCTURAL GENE ENCODING THE TYPE-B NEUROTOXIN AND DETERMINATION OF ITS ENTIRE NUCLEOTIDE-SEQUENCE APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 58(8), 2345-2354
BREHM, JK, PENNOCK, A, BULLMAN, HMS, YOUNG, M, OULTRAM, JD and MINTON, NP, 1992. PHYSICAL CHARACTERIZATION OF THE REPLICATION ORIGIN OF THE CRYPTIC PLASMID PCB101 ISOLATED FROM CLOSTRIDIUM-BUTYRICUM NCIB 7423 PLASMID. 28(1), 1-13 GODA, S.K, MINTON, N.P, BOTTING, N.P and GANI, D, 1992. Cloning, Sequencing, and Expression in Escherichia coli of the Clostridium tetanomorphum Gene Encoding β-Methylaspartase and Characterization of the Recombinant Protein Biochemistry. 31(44), 10747-10756 BREHM, JK, CHAMBERS, SP, BROWN, KJ, ATKINSON, T and MINTON, NP, 1991. MOLECULAR-CLONING AND NUCLEOTIDE-SEQUENCE DETERMINATION OF THE BACILLUS-STEAROTHERMOPHILUS NCA-1503 SUPEROXIDE-DISMUTASE GENE AND ITS OVEREXPRESSION IN ESCHERICHIA-COLI APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 36(3), 358-363
NICHOLLS, DJ, SUNDARAM, TK, ATKINSON, T and MINTON, NP, 1990. CLONING AND NUCLEOTIDE-SEQUENCES OF THE MDH AND SUCD GENES FROM THERMUS-AQUATICUS B FEMS MICROBIOLOGY LETTERS. 70(1), 7-13 MINTON, NP, SWINFIELD, TJ, BREHM, JK and OULTRAM, JD, 1990. THE GRAM-POSITIVE CLONING VECTOR PBD64 AROSE BY A 1844 BP DELETION OF PC194 DERIVED DNA NUCLEIC ACIDS RESEARCH. 18(6), 1651-1651 THOMPSON, DE, BREHM, JK, OULTRAM, JD, SWINFIELD, TJ, SHONE, CC, ATKINSON, T, MELLING, J and MINTON, NP, 1990. THE COMPLETE AMINO-ACID-SEQUENCE OF THE CLOSTRIDIUM-BOTULINUM TYPE-A NEUROTOXIN, DEDUCED BY NUCLEOTIDE-SEQUENCE ANALYSIS OF THE ENCODING GENE EUROPEAN JOURNAL OF BIOCHEMISTRY. 189(1), 73-81 SWINFIELD, TJ, OULTRAM, J.D, THOMPSON, D.E, BREHM, J.K and MINTON, N.P, 1990. Physical characterisation of the replication region of the Streptococcus faecalis plasmid pAMβ1 Gene. 87(1), 79-90 NICHOLLS, DJ, MINTON, NP, ATKINSON, T and SUNDARAM, TK, 1989. CLONING SEQUENCING AND OVER-EXPRESSION OF ESCHERICHIA-COLI MALATE-DEHYDROGENASE APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 31(4), 376-382
MINTON, NP, WHITEHEAD, PJ, ATKINSON, T and GILBERT, HJ, 1989. NUCLEOTIDE-SEQUENCE OF AN ERWINIA-CHRYSANTHEMI GENE ENCODING SHIKIMATE KINASE NUCLEIC ACIDS RESEARCH. 17(4), 1769-1769 YOUNG, M, MINTON, NP and STAUDENBAUER, WL, 1989. RECENT ADVANCES IN THE GENETICS OF THE CLOSTRIDIA FEMS MICROBIOLOGY LETTERS. 63(4), 301-325 CHAMBERS, SP, PRIOR, SE, EVANS, RA, SHERWOOD, RF and MINTON, NP, 1988. PLASMID PMTL153 - A HIGH COPY NUMBER VERSION OF PAT153 AND ITS USE TO OBTAIN HIGH EXPRESSION OF THE PSEUDOMONAS CARBOXYPEPTIDASE G2 GENE APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 29(6), 572-578
OULTRAM, JD, PECK, H, BREHM, JK, THOMPSON, DE, SWINFIELD, TJ and MINTON, NP, 1988. INTRODUCTION OF GENES FOR LEUCINE BIOSYNTHESIS FROM CLOSTRIDIUM-PASTEURIANUM INTO CLOSTRIDIUM-ACETOBUTYLICUM BY COINTEGRATE CONJUGAL TRANSFER MOLECULAR & GENERAL GENETICS. 214(1), 177-179
MINTON, NP, OULTRAM, JD, BREHM, JK and ATKINSON, T, 1988. THE REPLICATION PROTEINS OF PLASMIDS PE194 AND PLS1 HAVE N-TERMINAL HOMOLOGY NUCLEIC ACIDS RESEARCH. 16(7), 3101-3101 MINTON, NP and OULTRAM, JD, 1988. HOST - VECTOR SYSTEMS FOR GENE CLONING IN CLOSTRIDIUM MICROBIOLOGICAL SCIENCES. 5(10), 310-315
GILBERT, HJ, SULLIVAN, DA, JENKINS, G, KELLETT, LE, MINTON, NP and HALL, J, 1988. MOLECULAR-CLONING OF MULTIPLE XYLANASE GENES FROM PSEUDOMONAS-FLUORESCENS SUBSP CELLULOSA JOURNAL OF GENERAL MICROBIOLOGY. 134, 3239-3247
OULTRAM, JD, LOUGHLIN, M, SWINFIELD, TJ, BREHM, JK, THOMPSON, DE and MINTON, NP, 1988. INTRODUCTION OF PLASMIDS INTO WHOLE CELLS OF CLOSTRIDIUM-ACETOBUTYLICUM BY ELECTROPORATION FEMS MICROBIOLOGY LETTERS. 56(1), 83-88
NICHOLLS, D.J, SUNDARAM, T.K, ATKINSON, T and MINTON, N.P, 1988. Nuleotide sequence of the sucdinyI-CoA synthetase alpha-subunit from Thermus aquaticus B Nucleic Acids Research. 16(20), 9858 BARSTOW, D, MURPHY, J, SHARMAN, A, ATKINSON, T and MINTON, N, 1987. SEQUENCE OF THE BACILLUS-CALDOTENAX AND BACILLUS-STEAROTHERMOPHILUS LCTB GENES NUCLEIC ACIDS RESEARCH. 15(3), 1331-1331 SHUTTLEWORTH, HL, DUGGLEBY, CJ, JONES, SA, ATKINSON, T and MINTON, NP, 1987. NUCLEOTIDE-SEQUENCE ANALYSIS OF THE GENE FOR PROTEIN-A FROM STAPHYLOCOCCUS-AUREUS COWAN-1 (NCTC8530) AND ITS ENHANCED EXPRESSION IN ESCHERICHIA-COLI GENE. 58(2-3), 283-295 SHUTTLEWORTH, H, TAYLOR, J and MINTON, N, 1986. SEQUENCE OF THE GENE FOR ALKALINE-PHOSPHATASE FROM ESCHERICHIA-COLI JM83 NUCLEIC ACIDS RESEARCH. 14(21), 8689-8689 GILBERT, HJ, BLAZEK, R, BULLMAN, HMS and MINTON, NP, 1986. CLONING AND EXPRESSION OF THE ERWINIA-CHRYSANTHEMI ASPARAGINASE GENE IN ESCHERICHIA-COLI AND ERWINIA-CAROTOVORA JOURNAL OF GENERAL MICROBIOLOGY. 132, 151-160
MINTON, NP, BULLMAN, HMS, SCAWEN, MD, ATKINSON, T and GILBERT, HJ, 1986. NUCLEOTIDE-SEQUENCE OF THE ERWINIA-CHRYSANTHEMI NCPPB 1066 L-ASPARAGINASE GENE GENE. 46(1), 25-35 BARSTOW, DA, CLARKE, AR, CHIA, WN, WIGLEY, D, SHARMAN, AF, HOLBROOK, JJ, ATKINSON, T and MINTON, NP, 1986. CLONING, EXPRESSION AND COMPLETE NUCLEOTIDE-SEQUENCE OF THE BACILLUS-STEAROTHERMOPHILUS L-LACTATE DEHYDROGENASE GENE GENE. 46(1), 47-55 MINTON, NP and CLARKE, LE, 1985. IDENTIFICATION OF THE PROMOTER OF THE PSEUDOMONAS GENE CODING FOR CARBOXYPEPTIDASE-G2 JOURNAL OF MOLECULAR AND APPLIED GENETICS. 3(1), 26-35
CLARKE, LE, GIBSON, RF, SHERWOOD, RF and MINTON, NP, 1985. EXPRESSION OF THE PSEUDOMONAS GENE CODING FOR CARBOXYPEPTIDASE-G2 IN SACCHAROMYCES-CEREVISIAE JOURNAL OF GENERAL MICROBIOLOGY. 131(APR), 897-903
ATKINSON, T, BARSTOW, DA, JONES, SA, MINTON, NP and SHERWOOD, RF, 1984. CLONING ENZYME GENES FOR OVERPRODUCTION BIOCHEMICAL SOCIETY TRANSACTIONS. 12(2), 215-218 MINTON, NP, ATKINSON, T and SHERWOOD, RF, 1983. MOLECULAR-CLONING OF THE PSEUDOMONAS CARBOXYPEPTIDASE-G2 GENE AND ITS EXPRESSION IN ESCHERICHIA-COLI AND PSEUDOMONAS-PUTIDA JOURNAL OF BACTERIOLOGY. 156(3), 1222-1227
MINTON, NP and MORRIS, JG, 1983. REGENERATION OF PROTOPLASTS OF CLOSTRIDIUM-PASTEURIANUM ATCC-6013 JOURNAL OF BACTERIOLOGY. 155(1), 432-434
MINTON, NP, MARSH, J and ATKINSON, T, 1983. THE R-FACTORS OF MULTIPLE ANTIBIOTIC-RESISTANT FECAL COLIFORMS ISOLATED FROM A DOMESTIC DOG JOURNAL OF APPLIED BACTERIOLOGY. 55(3), 445-452 MINTON, N, GUNN, J and BEACHAM, IR, 1979. NUCLEOSIDE DIPHOSPHATE SUGAR HYDROLASE GENE OF SALMONELLA-TYPHIMURIUM - CHROMOSOMAL LOCATION DETERMINED BY INTERGENERIC CROSSES JOURNAL OF BACTERIOLOGY. 137(3), 1428-1429
MP DALWADI, Y WANG, JR KING and NP MINTON, Upscaling diffusion through first-order volumetric sinks: a homogenization of bacterial nutrient uptake SIAM Journal on Applied Mathematics. 29 (In Press.)