Liz Simpson

Contact

• workThe University of Nottingham Medical School
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 8230128
• fax0115 82 30142
• liz.simpson@nottingham.ac.uk

Recent Publications

• RABEN, ANNE, VESTENTOFT, PIA SIIG, BRAND-MILLER, JENNIE, JALO, ELLI, DRUMMEN, MATHJIS, SIMPSON, LIZ, MARTINEZ, J. ALFREDO, HANDJIEVA-DARLENSKA, TEODORA, STRATTON, GARETH, HUTTUNEN-LENZ, MAIJA, LAM, TONY, SUNDVALL, JOUKO, MUIRHEAD, ROSLYN, POPPITT, SALLY, RITZ, CHRISTIAN, PIETILAINEN, KIRSI H., WESTERTERP-PLANTENGA, MARGRIET, TAYLOR, MOIRA A., NAVAS-CARRETERO, SANTIAGO, HANDJIEV, SVETOSLAV, MCNARRY, MELITTA A., HANSEN, SYLVIA, RAMAN, LAURA, BRODIE, SHANNON, SILVESTRE, MARTA P., ADAM, TANJA C., MACDONALD, IAN A., SAN-CRISTOBAL, RODRIGO, BOYADJIEVA, NADKA, MACKINTOSH, KELLY A., SCHLICHT, WOLFGANG, LIU, AMY, LARSEN, THOMAS M. and FOGELHOLM, MIKAEL, 2021. The PREVIEW intervention study: Results from a 3-year randomized 2 x 2 factorial multinational trial investigating the role of protein, glycaemic index and physical activity for prevention of type 2 diabetes DIABETES OBESITY & METABOLISM. 23(2), 324-337
• CECILE BETRY, ALINE NIXON, PAUL GREENHAFF and ELIZABETH SIMPSON, 2020. Antecubital Vein Cannula Position Impacts Assessment of Forearm Glucose Uptake During an Oral Glucose Challenge in Healthy Volunteers Exp Clin Endocrinol Diabetes.
• SIMPSON, ELIZABETH J., CLARK, MARIE, RAZAK, AZLINA A. and SALTER, ANDREW, 2019. The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers FOOD & FUNCTION. 10(10), 6690-6698
• SARGEANT, JACK A., BAWDEN, STEPHEN, AITHAL, GURUPRASAD P., SIMPSON, ELIZABETH J., MACDONALD, IAN A., TURNER, MARK C., CEGIELSKI, JESSICA, SMITH, KENNETH, DORLING, JAMES L., GOWLAND, PENNY A., NIMMO, MYRA A. and KING, JAMES A., 2018. Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 118(4), 817-828

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• RABEN, ANNE, VESTENTOFT, PIA SIIG, BRAND-MILLER, JENNIE, JALO, ELLI, DRUMMEN, MATHJIS, SIMPSON, LIZ, MARTINEZ, J. ALFREDO, HANDJIEVA-DARLENSKA, TEODORA, STRATTON, GARETH, HUTTUNEN-LENZ, MAIJA, LAM, TONY, SUNDVALL, JOUKO, MUIRHEAD, ROSLYN, POPPITT, SALLY, RITZ, CHRISTIAN, PIETILAINEN, KIRSI H., WESTERTERP-PLANTENGA, MARGRIET, TAYLOR, MOIRA A., NAVAS-CARRETERO, SANTIAGO, HANDJIEV, SVETOSLAV, MCNARRY, MELITTA A., HANSEN, SYLVIA, RAMAN, LAURA, BRODIE, SHANNON, SILVESTRE, MARTA P., ADAM, TANJA C., MACDONALD, IAN A., SAN-CRISTOBAL, RODRIGO, BOYADJIEVA, NADKA, MACKINTOSH, KELLY A., SCHLICHT, WOLFGANG, LIU, AMY, LARSEN, THOMAS M. and FOGELHOLM, MIKAEL, 2021. The PREVIEW intervention study: Results from a 3-year randomized 2 x 2 factorial multinational trial investigating the role of protein, glycaemic index and physical activity for prevention of type 2 diabetes DIABETES OBESITY & METABOLISM. 23(2), 324-337
• CECILE BETRY, ALINE NIXON, PAUL GREENHAFF and ELIZABETH SIMPSON, 2020. Antecubital Vein Cannula Position Impacts Assessment of Forearm Glucose Uptake During an Oral Glucose Challenge in Healthy Volunteers Exp Clin Endocrinol Diabetes.
• SIMPSON, ELIZABETH J., CLARK, MARIE, RAZAK, AZLINA A. and SALTER, ANDREW, 2019. The impact of reduced red and processed meat consumption on cardiovascular risk factors; an intervention trial in healthy volunteers FOOD & FUNCTION. 10(10), 6690-6698
• SARGEANT, JACK A., BAWDEN, STEPHEN, AITHAL, GURUPRASAD P., SIMPSON, ELIZABETH J., MACDONALD, IAN A., TURNER, MARK C., CEGIELSKI, JESSICA, SMITH, KENNETH, DORLING, JAMES L., GOWLAND, PENNY A., NIMMO, MYRA A. and KING, JAMES A., 2018. Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY. 118(4), 817-828
• FOGELHOLM M, LARSEN TM, WESTERTERP-PLANTENGA M, MACDONALD I, MARTINEZ JA, BOYADJIEVA N, POPPITT S, SCHLICHT W, STRATTON G, SUNDVALL J, LAM T, JALO E, CHRISTENSEN P, DRUMMEN M, SIMPSON E, NAVAS-CARRETERO S, HANDJIEVA-DARLENSKA T, MUIRHEAD R, SILVESTRE MP, KAHLERT D, PASTOR-SANZ L, BRAND-MILLER J and RABEN A, 2017. PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial. Nutrients. 9(6),
• MEKJAVIC IB, AMON M, KÖLEGÅRD R, KOUNALAKIS SN, SIMPSON L, EIKEN O, KERAMIDAS ME and MACDONALD IA, 2016. The Effect of Normobaric Hypoxic Confinement on Metabolism, Gut Hormones, and Body Composition. Frontiers in physiology. 7, 202
• SIMPSON EJ, DEBEVEC T, EIKEN O, MEKJAVIC I and MACDONALD IA, 2016. PlanHab: the combined and separate effects of 16 days of bed rest and normobaric hypoxic confinement on circulating lipids and indices of insulin sensitivity in healthy men. Journal of applied physiology (Bethesda, Md. : 1985). 120(8), 947-55
• SIMPSON EJ, MENDIS B and MACDONALD IA, 2016. Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome; a randomised, controlled trial in an at-risk population. Food & function. 7(4), 1884-91
• DEBEVEC T, SIMPSON EJ, MEKJAVIC IB and EIKEN O,, 2016. Effects of prolonged hypoxia and bed rest on appetite and appetite-related hormones. Debevec T, Simpson EJ, Mekjavic IB, Eiken O, Macdonald IA. Appetite. 107, PMID: 27395413
• DEBEVEC T, BALI TC, SIMPSON EJ, MACDONALD IA, EIKEN O and MEKJAVIC IB, 2014. Separate and combined effects of 21-day bed rest and hypoxic confinement on body composition. European journal of applied physiology. 114(11), 2411-25
• DEBEVEC T, SIMPSON EJ, MACDONALD IA, EIKEN O and MEKJAVIC IB, 2014. Exercise training during normobaric hypoxic confinement does not alter hormonal appetite regulation. PloS one. 9(6), e98874
• MENDIS, B., SIMPSON, E., MACDONALD, I. and MANSELL, P., 2012. Investigation of the haemodynamic effects of exenatide in healthy male subjects British Journal of Clinical Pharmacology. 74(3), 437-444
• PITTAS G, HAZELL MD, SIMPSON EJ and GREENHAFF PL, 2010. Optimization of insulin-mediated creatine retention during creatine feeding in humans. Journal of sports sciences. 28(1), 67-74
• STEVENSON, E.J., ASTBURY, N.M., SIMPSON, E.J., TAYLOR, M.A. and MACDONALD, I.A., 2009. Fat oxidation during exercise and satiety during recovery are increased following a low-glycemic index breakfast in sedentary women Journal of Nutrition. 139(5), 890-897
• SIMPSON, E.J., HOLDSWORTH, M. and MACDONALD, I.A., 2008. Interstitial glucose profile associated with symptoms attributed to hypoglycemia by otherwise healthy women American Journal of Clinical Nutrition. 87(2), 354-361
• GREENHAFF, P.L., KARAGOUNIS, L.G., PIERCE, N,, SIMPSON, E.J., HAZELL, M., LAYFIELD, R., WACKERHAGE, H., SMITH, K., ATHERTON, P., SELBY, A. and RENNIE, M.J., 2008. Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle American Journal of Physiology: Endocrinology and Metabolism. 295(3), E595-E604
• STEPHENS FB, CONSTANTIN-TEODOSIU D, LAITHWAITE D, SIMPSON EJ and GREENHAFF PL, 2007. A threshold exists for the stimulatory effect of insulin on plasma L-carnitine clearance in humans. American journal of physiology. Endocrinology and metabolism. 292(2), E637-41
• STEPHENS, F.B., CONSTANTIN-TEODOSIU, D., LAITHWAITE, D., SIMPSON, E.J and GREENHAFF, P.L, 2006. Insulin stimulates L-carnitine accumulation in human skeletal muscle. FASEB Journal. 20(2), 377-379
• STEPHENS,F.B., CONSTANTIN-TEODOSIU,D., LAITHWAITE,D., SIMPSON,E.J. and GREENHAFF,P.L, 2006. An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle. Journal of Clinical Endocrinology and Metabolism. 91(12), 5013-5018
• SIMPSON, E.J., HOLDSWORTH, M. and MACDONALD, I.A., 2006. Ambulatory blood glucose measurement, dietary composition and physical activity levels in otherwise healthy women reporting symptoms that they attribute to hypoglycaemia British Journal of Nutrition. 95(6), 1127-33
• SIMPSON, E.J., HOLDSWORTH, M. and MACDONALD, I.A., 2006. Prevalence of self-reported symptoms attributed to hypoglycaemia within a general female population of the UK Journal of Psychosomatic Research. 60(4), 403-6
• TSINTZAS, K, SIMPSON, E J, SEEVARATNAM, N and JONES, S, 2003. Effect of exercise mode on blood glucose disposal during physiological hyperinsulinaemia in humans. European Journal of Applied Physiology. 89(2), 217-20
• KHAN, Z.H., SIMPSON, E.J., COLE, A.T., HOLT, M., MACDONALD, I.A., PYE, D., AUSTIN, A. and FREEMAN, J.G., 2003. Oesophageal cancer and cachexia: the effect of short-term treatment with thalidomide on weight loss and lean body mass Alimentary Pharmacology and Therapeutics. 17(5), 677-82
• CHHINA, N., KUESTERMANN, E., HALLIDAY, J., SIMPSON, L.J., MACDONALD, I.A., BACHELARD, H.S. and MORRIS, P.G., 2001. Measurement of human tricarboxylic acid cycle rates during visual activation by (13)C magnetic resonance spectroscopy Journal of Neuroscience Research. 66(5), 737-746
• STEENGE GR, SIMPSON EJ and GREENHAFF PL, 2000. Protein- and carbohydrate-induced augmentation of whole body creatine retention in humans. Journal of applied physiology (Bethesda, Md. : 1985). 89(3), 1165-71
• SIMPSON, E.J., CHAPMAN, M.A., DAWSON, J., BERRY, D., MACDONALD, I.A. and COLE, A., 2000. In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis Gut. 46(1), 73-77
• CONSTANTIN-TEODOSIU, D., SIMPSON, E. J. and GREENHAFF, P. L., 1999. The importance of pyruvate availability to PDC activation and anaplerosis in human skeletal muscle American Journal of Physiology. VOL 276(ISSUE 3), E472-E478
• CAVILL, G, SIMPSON, E J and MAHAJAN, R P, 1998. Factors affecting assessment of cerebral autoregulation using the transient hyperaemic response test. British Journal of Anaesthesia. 81(3), 317-21
• MAHAJAN, R P, CAVILL, G and SIMPSON, E J, 1998. Reliability of the transient hyperemic response test in detecting changes in cerebral autoregulation induced by the graded variations in end-tidal carbon dioxide. Anesthesia and Analgesia. 87(4), 843-9
• GREEN, A L, SIMPSON, E J, LITTLEWOOD, J J, MACDONALD, I A and GREENHAFF, P L, 1996. Carbohydrate ingestion augments creatine retention during creatine feeding in humans. Acta Physiologica Scandinavica. 158(2), 195-202
• SAMRA, J S, SIMPSON, E J, CLARK, M L, FORSTER, C D, HUMPHREYS, S M, MACDONALD, I A and FRAYN, K N, 1996. Effects of epinephrine infusion on adipose tissue: interactions between blood flow and lipid metabolism. American Journal of Physiology. 271(5 Pt 1), E834-9
• SAMRA, J S, SIMPSON, E J, CLARK, M L, FORSTER, C D, HUMPHREYS, S M, MACDONALD, I A and FRAYN, K N, 1996. Effects of adrenaline infusion on the interstitial environment of subcutaneous adipose tissue as studied by microdialysis. Clinical Science. 91(4), 425-30
• WEBBER, J, SIMPSON, E, PARKIN, H and MACDONALD, I A, 1994. Metabolic effects of acute hyperketonaemia in man before and during an hyperinsulinaemic euglycaemic clamp. Clinical Science. 86(6), 677-87
• MORIARTY, K T, SIMPSON, E J, MULLINGER, R N, MACDONALD, I A and TATTERSALL, R B, 1993. Antecedent insulin level and pattern of induction of acute hypoglycaemia do not affect subsequent counterregulatory responses in healthy subjects. Clinical Science. 85(5), 543-8
• MORIARTY, K T, SIMPSON, E J, BROWN, N S, MACDONALD, I A and TATTERSALL, R B, 1993. Effect of acute mild hypoglycaemia on counterregulatory responses to moderate hypoglycaemia induced immediately afterwards in healthy men. Clinical Science. 85(5), 537-42