Senior Research Fellow, Faculty of Science
I am interested in the mechanisms underlying cardiac (cellular) electrophysiology and how the interaction of dynamic processes at different scales (gene, ion channel, cell, tissue) gives rise to… read more
I am interested in the mechanisms underlying cardiac (cellular) electrophysiology and how the interaction of dynamic processes at different scales (gene, ion channel, cell, tissue) gives rise to organised behaviour at the level of the heart. I believe that computational models combined with novel experiments are our best tools to study both the healthy heartbeat and genetic, acquired, or drug-induced arrhythmias. But using models predictively for safety-criticial applications (such as drug safety-testing) requires a level of confidence that can only be achieved by improving our methods of data gathering (e.g. patch clamp experiments), analysis (e.g. parameter estimation), and reproducible & re-usable sharing.
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