Resources
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Glossary
- Acid: any substance that donates H+ ions; A solution that contains more H+ than OH- ions
- Base: any substance that removes free H+ from a solution
- Alkali: any substance that donates OH- ions into a solution; A solution that contains more OH- than H+ ions
- pH: the concentration of hydrogen ions (H+) in a solution
- Acidic: a solution containing excess H+ ions; a solution with a pH less than 7
- Alkaline: a solution containing fewer H+ than OH- ions; a solution with a pH greater than 7
- Neutral: a solution where there are exactly the same number of H+ and OH- ions
- Dissociation: molecules in solution break apart into ions and then re-form again
- Buffer: a molecule that can both accept H+ and donate that H+ ions
- Denaturation: alteration of a molecule's shape and structure leading to loss of function following rearrangement of its atoms
- Neutralisation: combination of an acid and an alkali to form a salt and water
- Salt: a molecule formed by the combination of an acid without its free H+ ions and an alkali without its OH- ions
Resources
| Title/link | Description |
|---|---|
| Centre for Reviews and Dissemination. | The CRD undertakes reviews of research about the effects of interventions used In health and social care. |
| Cochrane library. | The Cochrane Library contains high-quality, independent evidence to inform healthcare decision-making. It includes reliable evidence from Cochrane and other systematic reviews. |
| Health Technology Assessment (HTA) Programme. | The HTA programme works to provide all those who make decisions in the NHS with high-quality information on the costs, effectiveness and broader impact of health care treatments and tests. |
| Steps in conducting a systematic review. | This RLO outlines the five fundamental steps to conducting a systematic review of health care research so as identify, select and critically appraise relevant research. |
Books and Journals
| Egger M, Davey Smith G, Phillips AN. (1997) Meta-analysis: Principles and Procedures.BMJ;315:1533-1537. |
Meta-analysis - Print summary
This RLO covers the use of meta-analysis in summarising data from multiple studies to estimate the benefits of a particular treatment.
Learning outcomes
By completing this resource you should be able to describe:
- how meta-analysis is used to assess clinical effectiveness
- how pooling results from multiple studies improves precision.
By completing this resource you should be able to describe:
- how meta-analysis is used to assess clinical effectiveness
- how pooling results from multiple studies improves precision.
This resource was developed by:
Jo Leonardi-Bee - content author
Barry Wood, Liz Hilton - developers
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