Marianna Laviola
Assistant Professor, Faculty of Medicine & Health Sciences
Contact
Biography
I am a biomedical engineer and, in 2013, I obtained my PhD in Bioengineering at the Polytechnic University of Milan (Italy).
My research interests include the bioengineering of the respiratory and cardiovascular systems, the development of computational models of human physiology and pathology, animal models of respiratory diseases, ultrasonography of the diaphragm and opto-pletismography.
My research focusses on the development of computational simulation and mathematical modelling of the cardiopulmonary system as the primary methodology to model critically ill patients and develop personalised and optimised resuscitation and rescue strategies.
School Responsibilities:
Lead for Early Career Researchers - Injury, Inflammation and Recovery Science
Deputy Lead for PGR Student Teaching & Training - Doctoral Programmes - School of Medicine
Mentoring, coaching & tutoring
Mentor - UoN staff and students
Coach - SoM COALS programme
Tutor - SoM BMedSci students
Others
Associate Editor, IEEE Open Journal of Engineering in Medicine and Biology
Young Professional Representative (2020 -2022) - IEEE Engineering in Medicine and Biology Society (EMBS). Administrative Committee.
Teaching Summary
PGR supervision & BMedSci and PG research project supervision
"Introduction to MATLAB" - SoM PGR course
"Computational Modelling in Critical Illness" - SoM PGR course & Pluripotent Stem Cells module
Research Summary
Computational simulations and mathematical modelling of respiratory and cardiovascular systems
In silico trials
Cardiac arrest and resuscitation strategies
Apnoea and airway management in adults, pregnancy and children
Mechanical ventilation of the lungs
NIHR BRC Pump Priming project: "Computational modelling for optimisation and personalisation of resuscitation during critical hypotension and cardiac arrest secondary to trauma", 2023-24 PI (£5K)
University of Nottingham - Joan Browne PhD studentship: "Investigation of hypoxemia and hypercapnia during apnoea in children using a computer simulation", 2023-26 PI (UKRI PhD stipend and fees)
Fisher & Paykel Healthcare: "Nasal High Flow (NHF) for respiratory support, in silico research", 2022-26 Co-I (£75K)
WT Biomedical Vacation Scholarship: Simulation of cardiopulmonary resuscitation strategies in myocardial infarction and asphyxia using an integrated and high fidelity computational model", 2022. PI (£2K)
Animal Free Research UK: "Simulation of myocardial infarction and hypovolemic shock using an integrated and high fidelity computational model", 2021. PI (£2K)
EPRSC: "Investigating strategies for mechanical ventilation in COVID-19 via computational simulation of virtual patients", 2020-21. Researcher Co-I (£429K)
Fisher & Paykel Healthcare: "Investigating the evolution and application of Optiflow in managing obese patients in the perioperative period", 2019-22. Co-I (£76K)
NC3Rs: "Replacement of animal models of cardiac arrest and resuscitation strategies using a computer simulation", 2019-22. Co-I (£90K)
EPRSC: "Personalised Simulation Technologies for Optimising Treatment in the Intensive Care Unit: Realising Industrial and Medical Applications", 2017-21. Research Co-I (£880K)
Fisher & Paykel Healthcare: "Investigating the mechanism of Optiflow-induced gas exchange and potential optimizations using high-fidelity computational modelling", 2016-2017. Named Researcher. (£110k)
Past Research
October 2013 - September 2015 (Post-doc, Czech Technical University in Prague, Czech Republic)
Investigation of gas exchanges in animal models of ARDS during conventional ventilation and high-frequency oscillatory ventilation.
January 2010 - April 2013 (PhD thesis, Politecnico di Milano, Italy)
PhD thesis: "Development of new methods for noninvasive functional assessment of the diaphragm"