Tuesday, 18 March 2025
Scientists have successfully mapped the genome sequence of Aegilops mutica, a wild relative of wheat, shedding light on its genetic diversity and potential use in breeding programmes.
Researchers at the University of Nottingham assembled a chromosome-level haplotype-resolved genome sequence of Aegilops mutica. The research has been published in Scientific Data and contributes to a growing body of research aimed at safeguarding global wheat production in the face of climate change and emerging plant diseases.
The study was led by Dr Surbhi Grewal, Assistant Professor in the School of Biosciences and conducted as part of the Nottingham Wheat Research Centre’s (WRC) ongoing pre-breeding programme.
The breeding programme aims to introduce beneficial genetic diversity from wild species into cultivated wheat varieties. By using specialist sequencing techniques, Dr Grewal, along with her colleagues at the University of Nottingham and collaborators at the Wellcome Sanger Institute and Earlham Institute, have produced a high-quality fully-annotated genome assembly and valuable insights into the genetic architecture of Aegilops mutica, a species known for its adaptability to challenging environmental conditions.
This high-resolution genome assembly represents a significant step forward in our ability to utilise wild relatives for wheat improvement. With traits such as wheat rust resistance, as demonstrated in our past studies, present in Aegilops mutica, this resource opens new possibilities for enhancing the resilience of modern wheat.
For over a decade, the Nottingham Wheat Research Centre has been developing wheat-Aegilops mutica introgression lines, aiming to transfer beneficial traits from this wild species into cultivated wheat. These efforts have laid the foundation for identifying and integrating novel genetic diversity into wheat breeding programmes.
The research employs wheat chromosome-specific molecular markers and advanced genomic tools to track introgressions from wild relatives into breeding lines, with a particular focus on traits that enhance stress tolerance and disease resistance. The newly assembled genome will greatly enhance the identification of these beneficial traits, allowing wheat breeders to transfer them into their elite breeding material and efficiently track the beneficial introgressions.
Last year, the team also published the genome assembly of Triticum timopheevii, another wheat wild relative, further expanding the genomic resources available for wheat.
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More information is available from Dr Surbhi Grewal at surbhi.grewal@nottingham.ac.uk or
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About the University of Nottingham
Ranked 24 in Europe and 15th in the UK by the QS World University Rankings: Europe 2024, the University of Nottingham is a founding member of Russell Group of research-intensive universities. Studying at the University of Nottingham is a life-changing experience, and we pride ourselves on unlocking the potential of our students. We have a pioneering spirit, expressed in the vision of our founder Sir Jesse Boot, which has seen us lead the way in establishing campuses in China and Malaysia - part of a globally connected network of education, research and industrial engagement.
Nottingham was crowned Sports University of the Year by The Times and Sunday Times Good University Guide 2024 – the third time it has been given the honour since 2018 – and by the Daily Mail University Guide 2024.
The university is among the best universities in the UK for the strength of our research, positioned seventh for research power in the UK according to REF 2021. The birthplace of discoveries such as MRI and ibuprofen, our innovations transform lives and tackle global problems such as sustainable food supplies, ending modern slavery, developing greener transport, and reducing reliance on fossil fuels.
The university is a major employer and industry partner - locally and globally - and our graduates are the third most targeted by the UK's top employers, according to The Graduate Market in 2024 report by High Fliers Research.
We lead the Universities for Nottingham initiative, in partnership with Nottingham Trent University, a pioneering collaboration between the city’s two world-class institutions to improve levels of prosperity, opportunity, sustainability, health and wellbeing for residents in the city and region we are proud to call home.
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