Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: HAMAD BK, PATHAK M, MANNA R, FISCHER PM, EMSLEY J and DEKKER LV, 2017. Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation. Journal of thrombosis and haemostasis : JTH. (In Press.)

Content: MOHAMMED BM, MATAFONOV A, IVANOV I, SUN MF, CHENG Q, DICKESON SK, LI C, SUN D, VERHAMME IM, EMSLEY J and GAILANI D, 2017. An update on factor XI structure and function. Thrombosis research. 161, 94-105

Content: METZLER VM, DE BROT S, ROBINSON RS, JEYAPALAN JN, RAKHA E, WALTON T, GARDNER DS, LUND EF, WHITCHURCH J, HAIGH D, LOCHRAY JM, ROBINSON BD, ALLEGRUCCI C, FRAY RG, PERSSON JL, ØDUM N, MIFTAKHOVA RR, RIZVANOV AA, HUGHES IA, TADOKORO-CUCCARO R, HEERY DM, RUTLAND CS and MONGAN NP, 2017. Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development. Placenta. S0143-4004(17), 30164-9

Content: ATIOMO W, SHAFIEE MN, CHAPMAN C, METZLER VM, ABOUZEID J, LATIF A, CHADWICK A, KITSON S, SIVALINGAM VN, STRATFORD IJ, RUTLAND CS, PERSSON JL, ØDUM N, FUENTES-UTRILLIA P, JEYAPALAN JN, HEERY DM, CROSBIE EJ and MONGAN NP, 2017. Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with Polycystic Ovary Syndrome. Clinical endocrinology.

Content: PENNINGTON LF, ALOUFFI A, MBANEFO EC, RAY D, HEERY DM, JARDETZKY TS, HSIEH MH and FALCONE FH, 2017. H-IPSE is a pathogen-secreted host nucleus infiltrating protein (infiltrin) expressed exclusively by the Schistosoma haematobium egg stage. Infection and Immunity. 85(12),

Content: FISCHER, PETER M., 2017. Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview Medicinal Research Reviews. 37(2), 314-367

Content: KAREEM HAMED B, PATHAK M, MANNA R, FISCHER PM, EMSLEY J and DEKKER LV, 2017. Assessment of the protein interaction between Coagulation Factor XII and Corn Trypsin Inhibitor by molecular docking and biochemical validation Journal of Thrombosis and Haemostasis. 15(9), 1818-1828

Content: LEE, JONG BONG, ADROWER, CECILIA, QIN, CHAOLONG, FISCHER, PETER M., DE MOOR, CORNELIA H. and GERSHKOVICH, PAVEL, 2017. Development of Cordycepin Formulations for Preclinical and Clinical Studies: AAPS PharmSciTech AAPS PharmSciTech. (In Press.)

Content: CRESPILLO-CASADO, ANA, CHAMBERS, JOSEPH E., FISCHER, PETER M., MARCINIAK, STEFAN J. and RON, DAVID, 2017. PPP1R15A-mediated dephosphorylation of eIF2α is unaffected by Sephin1 or Guanabenz: eLife eLife. 6, e26109

Content: LEE, J. B., ZGAIR, A., TAHA, D. A., ZANG, X., KAGAN, L., KIM, T. H., KIM, M. G., YUN, H. Y., FISCHER, P. M. and GERSHKOVICH, P., 2017. Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays European Journal of Pharmaceutics and Biopharmaceutics. 114, 38-42

Content: AHMED M, CHAUDHARI K, BABAEI-JADIDI R, DEKKER LV and NATERI AS, 2017. Emerging Drugs Targeting Epithelial Cancer Stem-like Cells: A Concise Review. Stem cells (Dayton, Ohio). 35(4), 839-850

Content: SCHWEHM, CAROLIN, KELLAM, BARRIE, GARCES, AIMIE E., HILL, STEPHEN J., KINDON, NICHOLAS D., BRADSHAW, TRACEY D., LI, JIN, MACDONALD, SIMON J. F., ROWEDDER, JAMES E., STODDART, LEIGH A. and STOCKS, MICHAEL J., 2017. Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C–C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase $delta$ (PI3K$delta$) Inhib Journal of Medicinal Chemistry. acs.jmedchem.6b01801

Content: PANDUGA V, STOCKS MJ and BOSQUILLON C, 2017. Ipratropium is 'luminally recycled' by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers. International journal of pharmaceutics. (In Press.)

Content: KINDON, NICHOLAS, ANDREWS, GLEN, BAXTER, ANDREW, CHESHIRE, DAVID, HEMSLEY, PAUL, JOHNSON, TIMOTHY, LIU, YU-ZHEN, MCGINNITY, DERMOT, MCHALE, MARK, METE, ANTONIO, REUBERSON, JAMES, ROBERTS, BRYAN, STEELE, JOHN, TEOBALD, BARRY, UNITT, JOHN, VAUGHAN, DEBORAH, WALTERS, IAIN and STOCKS, MICHAEL J., 2017. Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists ACS Medicinal Chemistry Letters. acsmedchemlett.7b00315

Content: KINDON N, DAVIS A, DOUGALL I, DIXON J, JOHNSON T, WALTERS I, THOM S, MCKECHNIE K, MEGHANI P and STOCKS MJ, 2017. From UTP to AR-C118925, the discovery of a potent non nucleotide antagonist of the P2Y2 receptor. Bioorganic & medicinal chemistry letters. 27(21), 4849-4853

Publications