Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: DREES SL, LI C, PRASETYA F, SALEEM M, DREVENY I, WILLIAMS P, HENNECKE U, EMSLEY J and FETZNER S, 2016. PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM. J Biol Chem. 291(13), 6610-24

Content: WONG SS, ØSTERGAARD S, HALL G, LI C, WILLIAMS PM, STENNICKE H and EMSLEY J, 2016. A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain. Blood. 127(23), 2915-23

Content: MIFTAKHOVA R, HEDBLOM A, SEMENAS J, ROBINSON B, SIMOULIS A, MALM J, RIZVANOV A, HEERY DM, MONGAN NP, MAITLAND NJ, ALLEGRUCCI C and PERSSON JL, 2016. Cyclin A1 and P450 aromatase promote metastatic homing and growth of stem-like prostate cancer cells in the bone marrow Cancer Research. 76(8), 2453-64

Content: SARWAR M, SEMENAS J, MIFTAKHOVA R, SIMOULIS A, ROBINSON BD, WINGREN AG, MONGAN NP, HEERY DM, JOHNSSON H, ABRAHAMSSON PA, DIZEYI N, LUO J and PERSSON JL, 2016. Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells. Oncotarget. (In Press.)

Content: NURZYŃSKA, KATARZYNA, AUSTIN, RUPERT P., FISCHER, PETER M., BOOTH, JONATHAN and GOMMER, FRANK, 2016. Survival of the Fittest: Time-To-Event Modeling of Crystallization of Amorphous Poorly Soluble Drugs: Journal of Pharmaceutical Sciences Journal of Pharmaceutical Sciences. 105(6), 1858-1866

Content: SOUKARIEH, FADI, NOWICKI, MATTHEW W., BASTIDE, AMANDINE, POYRY, TUIJA, JONES, CAROLYN, DUDEK, KATE, PATWARDHAN, GEETANJALI, MEULLENET, FRANCOIS, OLDHAM, NEIL J., WALKINSHAW, MALCOLM D., WILLIS, ANNE E. and FISCHER, PETER M., 2016. Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. European Journal of Medicinal Chemistry. 124, 200-217

Content: ZGAIR, ATHEER, WONG, JONATHAN CM, LEE, JONG BONG, MISTRY, JATIN, SIVAK, OLENA, WASAN, KISHOR M, HENNIG, IVO M, BARRETT, DAVID A, CONSTANTINESCU, CRIS S, FISCHER, PETER M and GERSHKOVICH, PAVEL, 2016. Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines. American Journal of Translational Research. 8(8), 3448-59

Content: FRIDGEIRSDOTTIR GA, HARRIS R, FISCHER PM and ROBERTS CJ, 2016. Support Tools in Formulation Development for Poorly Soluble Drugs. Journal of Pharmaceutical Sciences. 105(8), 2260-9

Content: LEE JB, ZGAIR A, KIM TH, KIM MG, YOO SD, FISCHER PM and GERSHKOVICH P, 2016. Simple and sensitive HPLC-UV method for determination of bexarotene in rat plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1040, 73-80

Content: DISNEY AJ, KELLAM B and DEKKER LV, 2016. Alkylation of Staurosporine to Derive a Kinase Probe for Fluorescence Applications. ChemMedChem. 11(9), 972-9

Content: WOODHAM AW, SANNA AM, TAYLOR JR, SKEATE JG, DA SILVA DM, DEKKER LV and KAST WM, 2016. Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro. Virology journal. 13(1), 187

Content: FARAJI F, HU Y, YANG HH, LEE MP, WINKLER GS, HAFNER M and HUNTER KW, 2016. Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7. PLoS genetics. 12(1), e1005820

Content: ASHRAF, SADAF, BOUHANA, KARYN S., PHENEGER, JED, ANDREWS, STEVEN W. and WALSH, DAVID A., 2016. Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis ARTHRITIS RESEARCH & THERAPY. 18,

Content: JOSÉ RAMÓN YUSTE, SALLY EDITA FRANCO, CARLOS SANDERS, SEBASTIÁN CRUZ, MARCELO ERNESTO FERNÁNDEZ-RIVERO and GONZALO MORA, 2016. Bacillus licheniformis as a cause of a deep skin abscess in a 5-year-old girl: An exceptional case following a plant thorn injury Journal of Microbiology, Immunology and Infection. 49(5), 819 - 821

Content: SIMONETTI O, CIRIONI O, CACCIATORE I, BALDASSARRE L, ORLANDO F, PIERPAOLI E, LUCARINI G, ORSETTI E, PROVINCIALI M, FORNASARI E, DI STEFANO A, GIACOMETTI A and OFFIDANI A, 2016. Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound. PloS one. 11(6), e0151956

Publications