School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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DRINKWATER, N, VINH, NB, MISTRY, SN, BAMERT, RS, RUGGERI, C, HOLLERAN, JP, LOGANATHAN, S, PAIARDINI, A, CHARMAN, SA, POWELL, AK, AVERY, V, MCGOWAN, S and SCAMMELLS, PJ, 2016. Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions European Journal of Medicinal Chemistry. 110, 43-64

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MISTRY, SN, JORG, M, LIM, H, VINH, NB, SEXTON, PM, CAPUANO, B, CHRISTOPOULOS, A, LANE, JR, LANE, JR and SCAMMELLS, PJ, 2016. 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor Journal of Medicinal Chemistry. 59(1), 388-409

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MISTRY, SN, LIM, H, JORG, M, CAPUANO, B, CHRISTOPOULOS, A, LANE, JR and SCAMMELLS, PJ, 2016. Novel Fused Arylpyrimidinone Based Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor ACS Chemical Neuroscience. 7(5), 647-661

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CHOY KH, SHACKLEFORD DM, MALONE DT, MISTRY SN, PATIL RT, SCAMMELLS PJ, LANGMEAD CJ, PANTELIS C, SEXTON PM, LANE JR and CHRISTOPOULOS A, 2016. Positive Allosteric Modulation of the Muscarinic M1 Receptor Improves Efficacy of Antipsychotics in Mouse Glutamatergic Deficit Models of Behavior. The Journal of pharmacology and experimental therapeutics. 359(2), 354-365

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MISTRY, SHAILESH N. and BAKER, JILLIAN G., 2016. The effect of the N-alkyl moiety on the interaction of pindolol analogues with the two agonist conformations of the human β1-adrenoceptor In: 6th BPS Focused Meeting on Cell Signalling.

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MISTRY, SHAILESH N. and BAKER, JILLIAN G., 2016. The composite influence of the imidazolone moiety of CGP 12177 on its affinity and efficacy at the two conformations of the human β1-adrenoceptor In: 6th BPS Focused Meeting on Cell Signalling.

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BAKER, JG, GARDINER, SM, WOOLARD, J, FROMONT, C, JADHAV, GP, MISTRY, SN, THOMPSON, KS, KELLAM, B, HILL, SJ and FISCHER, PM, 2016. Development of novel selective beta 1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease In: BPS Pharmacology 2016.

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NESHEVA, D, MEDEIROS, LF, VERLI, H, ROESLER, R, MISTRY, SN and HOLLIDAY, ND, 2016. Development of a fluorescent ligand competition binding assay for the gastrin releasing peptide BB2 receptor In: BPS Pharmacology 2016.

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CINI, MELCHIOR, WILLIAMS, HUW, FAY, MIKE W., SEARLE, MARK S., WOODWARD, SIMON and BRADSHAW, TRACEY D., 2016. Enantiopure titanocene complexes - direct evidence for paraptosis in cancer cells METALLOMICS. 8(3), 286-297

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AL-HAYALI, M., LIM, K.H., KAM, T.S. and BRADSHAW, T.D., 2016. Conopantinine, a Novel Alkaloid with Anti-cancer Properties In: 17th Annual Drug Discovery Leaders Summit 2016 & 4th Annual Discovery Chemistry & Drug Design Congress 2016, at Berlin, Germany.

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QAZZAZ ME, RAJA VJ, LIM KH, KAM TS, LEE JB, GERSHKOVICH P and BRADSHAW TD, 2016. In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. Cancer letters. 370(2), 185-97

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COUSIN, DAVID, ZHANG, JIHONG, HUMMERSONE, MARC G., MATTHEWS, CHARLES S., FRIGERIO, MARK, BRADSHAW, TRACEY D. and STEVENS, MALCOLM F. G., 2016. Antitumor imidazo[5,1-d]-1,2,3,5-tetrazines: compounds modified at the 3-position overcome resistance in human glioblastoma cell lines MEDCHEMCOMM. 7(12), 2332-2343

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HAN LC, STANLEY PA, WOOD PJ, SHARMA P, KURUPPU AI, BRADSHAW TD and MOSES JE, 2016. Horner-Wadsworth-Emmons approach to piperlongumine analogues with potent anti-cancer activity. Organic & biomolecular chemistry. 14(31), 7585-93

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PATHAK M, WILMANN P, AWFORD J, LI C, HAMAD BK, FISCHER PM, DREVENY I, DEKKER LV and EMSLEY J, 2015. Coagulation factor XII protease domain crystal structure. Journal of Thrombosis and Haemostasis. 13(4), 580-591
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School of Pharmacy

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