Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: LAVADO, A.S., CHAUHAN, V.M., ALHAJ ZEN, A., GIUNTINI, F., JONES, D.R.E., BOYLE, R.W., BEEBY, A., CHAN, W.C. and AYLOTT, J.W., 2015. Controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells using porphyrin conjugated nanoparticles Nanoscale. 7(34), 14525-14531

Content: SPILIOTOPOULOS A, OWEN JP, MADDISON BC, DREVENY I, REES HC and GOUGH KC, 2015. Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets. Journal of immunological methods. 420, 50-5

Content: MARLOW, MARIA, AL-AMEEDEE, MOHAMMED, SMITH, THOMAS, WHEELER, SIMON and STOCKS, MICHAEL J., 2015. Linifanib - a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator CHEMICAL COMMUNICATIONS. 51(29), 6384-6387

Content: STOCKS, MICHAEL, 2015. Structure-Based Design of Drugs and Other Bioactive Molecules . Edited by Arun K. Ghosh and Sandra Gemma: ChemMedChem ChemMedChem. 10, 926-928

Content: STONE, ERICA L., CITOSSI, FRANCESCA, SINGH, RAJINDER, KAUR, BALVINDER, GASKELL, MARGARET, FARMER, PETER B., MONKS, ANNE, HOSE, CURTIS, STEVENS, MALCOLM F.G., LEONG, CHEE-ONN, STOCKS, MICHAEL, KELLAM, BARRIE, MARLOW, MARIA and BRADSHAW, TRACEY D., 2015. Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery: Bioorganic & Medicinal Chemistry Bioorganic & Medicinal Chemistry. 23, 6891-6899

Content: MARLOW, MARIA, AL-AMEEDEE, MOHAMMED, SMITH, THOMAS, WHEELER, SIMON and STOCKS, MICHAEL J., 2015. Linifanib – a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator: Chem. Commun. Chem. Commun.. 51, 6384-6387

Content: MITTAL, SHRUTI, CHOWHAN, RIMPY KAUR and SINGH, LAISHRAM RAJENDRAKUMAR, 2015. Macromolecular crowding: Macromolecules friend or foe BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1850(9), 1822-1831

Content: SHARMA, GURUMAYUM SURAJ, MITTAL, SHRUTI and SINGH, LAISHRAM RAJENDRAKUMAR, 2015. Effect of Dextran 70 on the thermodynamic and structural properties of proteins INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 79, 86-94

Content: COOK, AE, MISTRY, SN, GREGORY, KJ, FURNESS, SGB, SEXTON, PM, SCAMMELLS, PJ, CONIGRAVE, AD, CHRISTOPOULOS, A and LEACH, K, 2015. Biased allosteric modulation at the CaSR engendered by structurally diverse calcimimetics British Journal of Pharmacology. 172(1), 185-200

Content: PAIARDINI, A, BAMERT, RS, KANNAN-SIVARAMAN, K, DRINKWATER, N, MISTRY, SN, SCAMMELLS, PJ and MCGOWAN, S, 2015. Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18 PLOS ONE. 10(2), e0115859

Content: SHONBERG, J, DRAPER-JOYCE, C, MISTRY, SN, CHRISTOPOULOS, A, SCAMMELLS, PJ, LANE, JR and CAPUANO, B, 2015. Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D2 Receptor Journal of Medicinal Chemistry. 58(13), 5287-5307

Content: MISTRY, SN, SHONBERG, J, DRAPER-JOYCE, CJ, HERENBRINK, CK, MICHINO, M, SHI, L, CHRISTOPOULOS, A, CAPUANO, B, SCAMMELLS, PJ and LANE, JR, 2015. Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand Journal of Medicinal Chemistry.

Content: DRINKWATER, NYSSA, MISTRY, SHAILESH, SIVARAMAN, KOMAGAL KANNAN, PAIARDINI, ALESSANDRO, AVERY, VICKY, SCAMMELLS, PETER and MCGOWAN, SHEENA, 2015. Antimalarial Agents With a Novel Mode of Action: Dual Inhibition of P. falciparum M1 and M17 Metalloaminopeptidases PROTEIN SCIENCE. 24, 7-7

Content: A AHMED, C DE MATTEIS, N R THOMAS, G MANTOVANI and D BARRETT, 2015. Inhibiting InhA: new weapons in the fight against tuberculosis In: Gordon Research Conference - Challenges, Advances and Future Prospects in the Fight Against Tuberculosis, Spain.

Content: LIM, K.H., RAJA, V.J., BRADSHAW, T.D., LIM, S.H., LOW, Y.Y. and KAM, T.S., 2015. Ibogan, Tacaman, and Cytotoxic Bisindole Alkaloids from Tabernaemontana. Cononusine, an Iboga Alkaloid with Unusual Incorporation of a Pyrrolidone Moiety Journal of Natural Products. 78(5), 1129-1138

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