Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: MARLOW, MARIA, AL-AMEEDEE, MOHAMMED, SMITH, THOMAS, WHEELER, SIMON and STOCKS, MICHAEL J., 2015. Linifanib - a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator CHEMICAL COMMUNICATIONS. 51(29), 6384-6387

Content: STOCKS, MICHAEL, 2015. Structure-Based Design of Drugs and Other Bioactive Molecules . Edited by Arun K. Ghosh and Sandra Gemma: ChemMedChem ChemMedChem. 10, 926-928

Content: STONE, ERICA L., CITOSSI, FRANCESCA, SINGH, RAJINDER, KAUR, BALVINDER, GASKELL, MARGARET, FARMER, PETER B., MONKS, ANNE, HOSE, CURTIS, STEVENS, MALCOLM F.G., LEONG, CHEE-ONN, STOCKS, MICHAEL, KELLAM, BARRIE, MARLOW, MARIA and BRADSHAW, TRACEY D., 2015. Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery: Bioorganic & Medicinal Chemistry Bioorganic & Medicinal Chemistry. 23, 6891-6899

Content: MARLOW, MARIA, AL-AMEEDEE, MOHAMMED, SMITH, THOMAS, WHEELER, SIMON and STOCKS, MICHAEL J., 2015. Linifanib – a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator: Chem. Commun. Chem. Commun.. 51, 6384-6387

Content: MITTAL, SHRUTI, CHOWHAN, RIMPY KAUR and SINGH, LAISHRAM RAJENDRAKUMAR, 2015. Macromolecular crowding: Macromolecules friend or foe BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1850(9), 1822-1831

Content: SHARMA, GURUMAYUM SURAJ, MITTAL, SHRUTI and SINGH, LAISHRAM RAJENDRAKUMAR, 2015. Effect of Dextran 70 on the thermodynamic and structural properties of proteins INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 79, 86-94

Content: COOK, AE, MISTRY, SN, GREGORY, KJ, FURNESS, SGB, SEXTON, PM, SCAMMELLS, PJ, CONIGRAVE, AD, CHRISTOPOULOS, A and LEACH, K, 2015. Biased allosteric modulation at the CaSR engendered by structurally diverse calcimimetics British Journal of Pharmacology. 172(1), 185-200

Content: PAIARDINI, A, BAMERT, RS, KANNAN-SIVARAMAN, K, DRINKWATER, N, MISTRY, SN, SCAMMELLS, PJ and MCGOWAN, S, 2015. Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18 PLOS ONE. 10(2), e0115859

Content: SHONBERG, J, DRAPER-JOYCE, C, MISTRY, SN, CHRISTOPOULOS, A, SCAMMELLS, PJ, LANE, JR and CAPUANO, B, 2015. Structure–Activity Study of N-((trans)-4-(2-(7-Cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a Bitopic Ligand That Acts as a Negative Allosteric Modulator of the Dopamine D2 Receptor Journal of Medicinal Chemistry. 58(13), 5287-5307

Content: MISTRY, SN, SHONBERG, J, DRAPER-JOYCE, CJ, HERENBRINK, CK, MICHINO, M, SHI, L, CHRISTOPOULOS, A, CAPUANO, B, SCAMMELLS, PJ and LANE, JR, 2015. Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand Journal of Medicinal Chemistry.

Content: DRINKWATER, NYSSA, MISTRY, SHAILESH, SIVARAMAN, KOMAGAL KANNAN, PAIARDINI, ALESSANDRO, AVERY, VICKY, SCAMMELLS, PETER and MCGOWAN, SHEENA, 2015. Antimalarial Agents With a Novel Mode of Action: Dual Inhibition of P. falciparum M1 and M17 Metalloaminopeptidases PROTEIN SCIENCE. 24, 7-7

Content: A AHMED, C DE MATTEIS, N R THOMAS, G MANTOVANI and D BARRETT, 2015. Inhibiting InhA: new weapons in the fight against tuberculosis In: Gordon Research Conference - Challenges, Advances and Future Prospects in the Fight Against Tuberculosis, Spain.

Content: LIM, K.H., RAJA, V.J., BRADSHAW, T.D., LIM, S.H., LOW, Y.Y. and KAM, T.S., 2015. Ibogan, Tacaman, and Cytotoxic Bisindole Alkaloids from Tabernaemontana. Cononusine, an Iboga Alkaloid with Unusual Incorporation of a Pyrrolidone Moiety Journal of Natural Products. 78(5), 1129-1138

Content: KURUPPU, ANCHALA I., ZHANG, LEI, COLLINS, HILARY, TURYANSKA, LYUDMILA, THOMAS, NEIL R. and BRADSHAW, TRACEY D., 2015. An Apoferritin-based Drug Delivery System for the Tyrosine Kinase Inhibitor Gefitinib ADVANCED HEALTHCARE MATERIALS. 4(18), 2816-2821

Content: CINI, MELCHIOR, BRADSHAW, TRACEY D., WOODWARD, SIMON and LEWIS, WILLIAM, 2015. Asymmetric Pentafulvene Carbometalation-Access to Enantiopure Titanocene Dichlorides of Biological Relevance ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 54(47), 14179-14182

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