Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: WESAM S. QAYED, MOSTAFA A. HASSAN, WAEL M. EL-SAYED, JOSE ROGERIO A. SILVA and TAREK ABOUL-FADL, 2022. Novel Azine Linked Hybrids of 2-Indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies Bioorganic Chemistry. 126(105884),

Content: ELVA FRIDJONSDOTTIR, THEODOSIA VALLIANATOU, IOANNIS MANTAS, REZA SHARIATGORJI, ANNA NILSSON, LUKE S. SCHEMBRI, LUKE R. ODELL, PER SVENNINGSSON and PER E. ANDRÉN*, 2022. Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems ACS Chemical Biology. 17(1), 147-158

Content: MONAGHAN, T.M., SEEKATZ, A.M., MULLISH, B.H., MOORE-GILLON, C.E.R., DAWSON, L., AHMED, A., KAO, D. and CHAN, W.C., 2021. Clostridioides difficile: Innovations in target discovery and potential for therapeutic success Expert Opinion on Therapeutic Targets. 25(11), 949-963

Content: TARANTINI, F.S., BRUNATI, M., TARAVELLA, A., CARRANO, L., PARENTI, F., HONG, K.W., WILLIAMS, P., CHAN, K.G., HEEB, S. and CHAN, W.C., 2021. Actinomadura graeca sp. nov.: a novel producer of the macrocyclic antibiotic zelkovamycin PLoS ONE. 16(11), e0260413

Content: CHAN, W.C., GENAPATHY, S. and YANG, L., 2021. Antibacterial compounds US 11,192,888 B2 12/07/2021 00:00:00

Content: CHETTY, S., ARMSTRONG, T, DREWE, W.C., DREWE, W.C., DE MATTEIS, C.I., EVANGELOPOULOS, D., BHAKTA, S. and THOMAS, N.R., 2021. New InhA Inhibitors Based on Expanded Triclosan and Di-Triclosan Analogues to Develop a New Treatment for Tuberculosis Pharmaceuticals. 14(4), 361

Content: S MCDONALD, C DE MATTEIS, E NEWALL, F MCCULLOUGH, L MOTT, B VILLA MARCOS, V SOLANKI, N REA, R WRIGHT, S BAGLEY, S BAMFORD, Q WANG and A LAU, 2021. Exploring and supporting undergraduate students’ digital learning transition from school to university In: Horizons in STEM Higher Education Conference, Open University.

Content: COMEO, ELEONORA, TRINH, PHUC, NGUYEN, ANH T., NOWELL, CAMERON J., KINDON, NICHOLAS D., SOAVE, MARK, STODDART, LEIGH A., WHITE, JONATHAN M., HILL, STEPHEN J., KELLAM, BARRIE, HALLS, MICHELLE L., MAY, LAUREN T. and SCAMMELLS, PETER J., 2021. Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A(1) Receptor in Living Cells JOURNAL OF MEDICINAL CHEMISTRY. 64(10), 6670-6695

Content: SOUKARIEH, FADI, MASHABI, ALAA, RICHARDSON, WILLIAM, OTON, EDUARD VICO, ROMERO, MANUEL, ROBERSTON, SHAUN N., GROSSMAN, SCOTT, SOU, TOMAS, LIU, RUILING, HALLIDAY, NIGEL, KUKAVICA-IBRULJ, IRENA, LEVESQUE, ROGER C., BERGSTROM, CHRISTEL A. S., KELLAM, BARRIE, EMSLEY, JONAS, HEEB, STEPHAN, WILLIAMS, PAUL, STOCKS, MICHAEL J. and CAMARA, MIGUEL, 2021. Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa ACS INFECTIOUS DISEASES. 7(9), 2666-2685

Content: SOUKARIEH, FADI, MASHABI, ALAA, RICHARDSON, WILLIAM, OTON, EDUARD VICO, ROMERO, MANUEL, ROBERSTON, SHAUN N., GROSSMAN, SCOTT, SOU, TOMAS, LIU, RUILING, HALLIDAY, NIGEL, KUKAVICA-IBRULJ, IRENA, LEVESQUE, ROGER C., BERGSTROM, CHRISTEL A. S., KELLAM, BARRIE, EMSLEY, JONAS, HEEB, STEPHAN, WILLIAMS, PAUL, STOCKS, MICHAEL J. and CÁMARA, MIGUEL, 2021. Design and Evaluation of New Quinazolin-4(3H)‑one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa ACS Infectious Diseases. 7(9), 2666-2685

Content: DAMASKINAKI, FOTEINI-NAFSIKA, MORAN, LUIS A., GARCIA, ANGEL, KELLAM, BARRIE and WATSON, STEVE P., 2021. Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2 Platelets. 32(6), 744-752

Content: STODDART, LEIGH A., KILPATRICK, LAURA E., CORRIDEN, ROSS, KELLAM, BARRIE, BRIDDON, STEPHEN J. and HILL, STEPHEN J., 2021. Efficient G protein coupling is not required for agonist‐mediated internalization and membrane reorganization of the adenosine A3 receptor The FASEB Journal. 35(4), e21211

Content: COMEO, ELEONORA, TRINH, PHUC, NGUYEN, ANH T, NOWELL, CAMERON J, KINDON, NICHOLAS D, SOAVE, MARK, STODDART, LEIGH A, WHITE, JONATHAN M, HILL, STEPHEN J, KELLAM, BARRIE, HALLS, MICHELLE L, MAY, LAUREN T and SCAMMELLS, PETER J, 2021. Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A 1 Receptor in Living Cells Journal of Medicinal Chemistry. 64(10), 6670-6695

Content: GOULDING, JOËLLE, MISTRY, SARAH J., SOAVE, MARK, WOOLARD, JEANETTE, BRIDDON, STEPHEN J., WHITE, CARL W., KELLAM, BARRIE and HILL, STEPHEN J., 2021. Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels Pharmacology Research & Perspectives. 9(3), e00779

Content: SANCHEZ-BAILON, MARIA PILAR, CHOI, SOO-YOUN, DUFFICY, ELIZABETH R., SHARMA, KARAN, MCNEE, GAVIN S., GUNNELL, EMMA, CHIANG, KELLY, SAHAY, DEBASHISH, MASLEN, SARAH, STEWART, GRANT S., SKEHEL, J. MARK, DREVENY, INGRID and DAVIES, CLARE C., 2021. Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair NATURE COMMUNICATIONS. 12(1),

Publications