Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: VERNALL, ANDREA J., HILL, STEPHEN J and KELLAM, BARRIE, 2014. The evolving small-molecule fluorescent-conjugate toolbox for Class A GPCRs: British journal of pharmacology British journal of pharmacology. 171(5), 1073-1084

Content: SKILLING, KATHRYN J, CITOSSI, FRANCESCA, BRADSHAW, TRACEY D, ASHFORD, MARIANNE, KELLAM, BARRIE and MARLOW, MARIA, 2014. Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications.: Soft Matter Soft Matter. 10(2), 237-256

Content: STODDART, LEIGH A, KELLAM, BARRIE, BRIDDON, STEPHEN J and HILL, STEPHEN J, 2014. Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization.: British journal of pharmacology British journal of pharmacology. 171(16), 3827-3844

Content: SCHWEHM, CAROLIN, LEWIS, WILLIAM, BLAKE, ALEXANDER J, KELLAM, BARRIE and STOCKS, MICHAEL J, 2014. Preparation and structural analysis of (±)-cis-ethyl 2-sulfanylidenedecahydro-1,6-naphthyridine-6-carboxylate and (±)-trans-ethyl 2-oxooctahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate.: Acta crystallographica. Section C, Structural chemistry Acta crystallographica. Section C, Structural chemistry. 70(Pt 12), 1161-1168

Content: MURRAY, E.J., CROWLEY, R.C., TRUMAN, A., CLARKE, S.R., COTTAM, J.A., JADHAV, G.P., STEELE, V.R., O'SHEA, P., LINDHOLM, C., COCKAYNE, A., CHHABRA, S.R., CHAN, W.C. and WILLIAMS, P., 2014. Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors Journal of Medicinal Chemistry. 57(6), 2813-2819

Content: ALHAJ ZEN, A., AYLOTT, J.W. and CHAN, W.C., 2014. An appraisal of the Suzuki cross-coupling reaction for the synthesis of novel fluorescent coumarin derivatives Tetrahedron Letters. 55(40), 5521-5524

Content: DEMPSTER S, HARPER S, MOSES JE and DREVENY I, 2014. Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta crystallographica. Section D, Biological crystallography. 70(Pt 5), 1484-90

Content: HARPER S, GRATTON HE, CORNACIU I, OBERER M, SCOTT DJ, EMSLEY J and DREVENY I, 2014. Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains. Biochemistry. 53(18), 2966-78

Content: MICHAEL J STOCKS, LILIAN ALCARAZ, ANDREW BAILEY, ROGER BONNERT, ELAINE CADOGAN, JADEEN CHRISTIE, JOHN DIXON, STEPHEN CONNOLLY, ANTHONY COOK, STUART PAINE, 2014. Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action ACS Med Chem Lett.

Content: BRIOCHE, JULIEN, COURANT, THIBAUT, ALCARAZ, LILIAN, STOCKS, MICHAEL, FURBER, MARK, ZHU, JIEPING and MASSON, GÉRALDINE, 2014. Chiral Phosphoric Acid-Catalyzed Enantioselective Three- Component Aza-Diels-Alder Reactions of Aminopyrroles and Aminopyrazoles: Advanced Synthesis & Catalysis Advanced Synthesis & Catalysis. 356, 1719-1724

Content: STOCKS, MICHAEL J, ALCARAZ, LILIAN, BAILEY, ANDREW, BONNERT, ROGER, CADOGAN, ELAINE, CHRISTIE, JADEEN, DIXON, JOHN, CONNOLLY, STEPHEN, COOK, ANTHONY, FISHER, ADRIAN, FLAHERTY, ALICE, HUMPHRIES, ALEXANDER, INGALL, ANTHONY, JORDAN, STEPHEN, LAWSON, MANDY, MULLEN, ALEX, NICHOLLS, DAVID, PAINE, STUART, PAIRAUDEAU, GARRY and YOUNG, ALAN, 2014. Discovery of AZD3199, An Inhaled Ultralong Acting β 2 Receptor Agonist with Rapid Onset of Action: ACS Med. Chem. Lett. ACS Med. Chem. Lett.. 5, 416-421

Content: CHOWHAN, RIMPY K., MITTAL, SHRUTI, DAR, TANVEER A., KAMAL, MOHAMMAD A. and SINGH, LAISHRAM R., 2014. Ignored Avenues in Alpha-Synuclein Associated Proteopathy CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. 13(7), 1246-1257

Content: MITTAL SHRUTI and SINGH LSISHRAM RAJENDRAKUMAR, 2014. Macromolecular crowding induces holo α-lactalbumin aggregation by converting to its apo form PLoS One. 9(12),

Content: MITTAL SHRUTI and SINGH LAISHRAM RAJENDRAKUMAR, 2014. Macromolecular Crowding Decelerates Aggregation of a β-rich Protein, Bovine Carbonic Anhydrase: A Case Study. Journal of Biochemistry. 156(5), 273-282

Content: ABDUL-RIDHA, ALAA, LÓPEZ, LAURA, KEOV, PETER, THAL, DAVID M, MISTRY, SHAILESH N, SEXTON, PATRICK M, LANE, J ROBERT, CANALS, MERITXELL and CHRISTOPOULOS, ARTHUR, 2014. Molecular determinants of allosteric modulation at the M₁ muscarinic acetylcholine receptor Journal of Biological Chemistry. 289(9), 6067-6079

Publications