School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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COLLINS HM, ABDELGHANY MK, MESSMER M, YUE B, DEEVES SE, KINDLE KB, MANTELINGU K, ASLAM A, WINKLER GS, KUNDU TK and HEERY DM, 2013. Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells. BMC cancer. 13(1), 37

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BAY-RICHTER, C., O'CALLAGHAN, M.J., MATHUR, N., O'TUATHAIGH, C.M.P., HEERY, D.M., FONE, K.C.F, WADDINGTON, J.L. and MORAN, P.M., 2013. D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors Neuropsychopharmacology. 38(8), 1512-1520

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WADELIN FR, FULTON J, COLLINS HM, TERTIPIS N, BOTTLEY A, SPRIGGS KA, FALCONE FH and HEERY DM, 2013. PRAME is a golgi-targeted protein that associates with the Elongin BC complex and is upregulated by interferon-gamma and bacterial PAMPs. PloS one. 8(2), e58052

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CHAN, C.M., FULTON, J., MONTIEL-DUARTE, C., COLLINS, H.M., BHARTI, N., WADELIN, F.R., MORAN, P.M., MONGAN, N.P. and HEERY, D.M., 2013. A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors Nucleic Acids Research. 41(21), 9663-9679

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SHAO, HAO, SHI, SHENHUA, HUANG, SHILIANG, HOLE, ALISON, ABBAS, ABDULLAHI Y., BAUMLI, SONJA, LIU, XIANGRUI, LAM, FRANKIE, FOLEY, DAVID W., FISCHER, PETER M., NOBLE, MARTIN, ENDICOTT, JANE A., PEPPER, CHRIS and WANG, SHUDONG, 2013. Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, x-ray crystal structure, SAR and anti-cancer activities: Journal of Medicinal Chemistry Journal of Medicinal Chemistry. 56, 640-659

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MISTRY, S.N., BAKER, J.G., FISCHER, P.M., HILL, S.J., GARDINER, S.M. and KELLAM, B., 2013. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists Journal of Medicinal Chemistry. 56(10), 3852-3865

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MORENO, J.A., HALLIDAY, M., MOLLOY, C., RADFORD, H., VERITY, N., AXTEN, J.M., ORTORI, C.A., WILLIS, A.E., FISCHER, P.M., BARRETT, D.A. and MALLUCCI, G.R., 2013. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice: Science Translational Medicine Science Translational Medicine. 5(206), 206ra138

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MARYATI M, KAUR I, JADHAV GP, OLOTU-UMOREN L, OVEH B, HASHMI L, FISCHER PM and WINKLER GS, 2013. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity. Nucleic acids research. (In Press.)

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SHAO H, SHI S, FOLEY DW, LAM F, ABBAS AY, LIU X, HUANG S, JIANG X, BAHARIN N, FISCHER PM and WANG S, 2013. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. European journal of medicinal chemistry. 70, 447-55

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DICKENS MP, ROXBURGH P, HOCK A, MEZNA M, KELLAM B, VOUSDEN KH and FISCHER PM, 2013. 5-Deazaflavin derivatives as inhibitors of p53 ubiquitination by HDM2. Bioorganic & medicinal chemistry. 21(22), 6868-77

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WAHLE E and WINKLER GS, 2013. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Biochimica et biophysica acta. 1829(6-7), 561-70

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MARYATI, M., KAUR, I., JADHAV,G.P., OLOTU-UMOREN, L., OVEH, B., HASHMI, L., FISCHER, P.M. and WINKLER, G.S., 2013. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity Nucleic Acids Research. n/a(n/a), n/a

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WINKLER GS and BALACCO DL, 2013. Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex. Frontiers in genetics. 4, 296
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