School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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DICKENS, M.P., FITZGERALD, R. and FISCHER, P.M., 2009. Small-molecule inhibitors of MDM2 as new anticancer therapeutics Seminars in Cancer Biology. 20(1), 10-18

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KONTOPIDIS, G., ANDREWS, M.J, MCINNES, C., PLATER, A., INNES, L., RENACHOWSKI, S., COWAN, A. and FISCHER, P.M., 2009. Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design. ChemMedChem. 4(7), 1120-8

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FISCHER, P.M., 2009. Cap in hand: targeting eIF4E Cell Cycle. 8(16), 2535-2541

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MAZANETZ, M.P., WITHERS, I.M., LAUGHTON, C.A. and FISCHER, P.M., 2009. A Study of CDK2 Inhibitors Using a Novel 3D-QSAR Method Based on Exploitation of Receptor Flexibility QSAR & Combinatorial Science. 28(8), 878-884

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PACLET, M.H., DAVIDSON-MONCADA, J., LOPEZ-LLUCH, G., SHAO, D. and DEKKER, L.V., 2009. Protein Kinase C as an effector of lipid-derived second messengers. In: LARIJANI, B., WOSCHOLSKI, R. and ROSSER, C.A., eds., Lipid signalling protocols 462. Humana Press Inc, Totowa, USA. 253-263

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FRONTINI, M., VIJAYAKUMAR, M., GARVIN, A. and CLARKE, N., 2009. A ChIP-chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response Nucleic Acids Research. 37(4), 1073-1085

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ASLAM, A., MITTAL, S., KOCH, F., ANDRAU, J.-C. and WINKLER, G.S., 2009. The Ccr4-Not deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation Molecular Biology of the Cell. 20(17), 3840-3850

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HUANG, A., DE JONG, R.N., WIENK, H., WINKLER, G.S., TIMMERS, H.T.M. and BOELENS, R., 2009. E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity Journal of Molecular Biology. 385(2), 507-519

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DUDUIALA, C.-I., WATTIS, J.A.D., DRYDEN, I.L. and LAUGHTON, C.A., 2009. Nonlinear breathing modes at a defect site in DNA (15 pages) Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. VOL 80(NUMB 6), 061906

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COOKSON, J C and LAUGHTON, C A, 2009. The levels of telomere-binding proteins in human tumours and therapeutic implications. European journal of cancer (Oxford, England : 1990). 45(4), 536-50

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WANG, HAO and LAUGHTON, CHARLES A, 2009. Evaluation of molecular modelling methods to predict the sequence-selectivity of DNA minor groove binding ligands. Physical chemistry chemical physics : PCCP. 11(45), 10722-8

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LAUGHTON, CHARLES A, OROZCO, MODESTO and VRANKEN, WIM, 2009. COCO: a simple tool to enrich the representation of conformational variability in NMR structures. Proteins. 75(1), 206-16

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KOENEN, R. R., VON HUNDELSHAUSEN, P., NESMELOVA, I. V., ZERNECKE, A., LIEHN, E. A., SARABI, A., KRAMP, B. K., PICCININI, A. M., PALUDAN, S. R., KOWALSKA, M. A., KUNGL, A. J., HACKENG, T. M., MAYO, K. H. and WEBER, C., 2009. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice: Nat Med Nat Med. 15(1), 97-103

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MIDWOOD, K., SACRE, S., PICCININI, A. M., INGLIS, J., TREBAUL, A., CHAN, E., DREXLER, S., SOFAT, N., KASHIWAGI, M., OREND, G., BRENNAN, F. and FOXWELL, B., 2009. Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease: Nat Med Nat Med. 15(7), 774-80

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MIDWOOD, K. S., PICCININI, A. M. and SACRE, S., 2009. Targeting Toll-like receptors in autoimmunity: Curr Drug Targets Curr Drug Targets. 10(11), 1139-55
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