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Publications in the Biomolecular Science and Medicinal Chemistry Division

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Content: MIDWOOD, K., SACRE, S., PICCININI, A. M., INGLIS, J., TREBAUL, A., CHAN, E., DREXLER, S., SOFAT, N., KASHIWAGI, M., OREND, G., BRENNAN, F. and FOXWELL, B., 2009. Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease: Nat Med Nat Med. 15(7), 774-80

Content: MIDWOOD, K. S., PICCININI, A. M. and SACRE, S., 2009. Targeting Toll-like receptors in autoimmunity: Curr Drug Targets Curr Drug Targets. 10(11), 1139-55

Content: ABULATEEFEH, S.R., SAEED, A.O., AYLOTT, J.W., CHAN, W.C., GARNETT, M.C., SAUNDERS, B.R. and ALEXANDER, C., 2009. Facile synthesis of responsive nanoparticles with reversible, tuneable and rapid thermal transitions from biocompatible constituents Chemical Communications. 2009(40), 6068-6070

Content: WELSER, K., AYAL PERERA, M.D., AYLOTT, J.W. and CHAN, W.C., 2009. A facile method to clickable sensing polymeric nanoparticles Chemical Communications. 2009(43), 6601-6603

Content: WELSER, KATHARINA, GRILJ, JAKOB, VAUTHEY, ERIC, AYLOTT, JONATHAN W. and CHAN, WENG C., 2009. Protease responsive nanoprobes with tethered fluorogenic peptidyl 3-arylcoumarin substrates Chemical Communications. 671-673

Content: DREVENY, I., ANDRYUSHKOVA, A.S., GLIEDER, A., GRUBER, K. and KRATKY, C., 2009. Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity Biochemistry. 48(15), 3370-3377

Content: STOCKS MJ, WILDEN GRH, PAIRAUDEAU G, PERRY MWD, STEELE J and STONEHOUSE JP, 2009. A practical method for targeted library design balancing lead-like properties with diversity. Chemmedchem. 4(5), 800-8

Content: SMITH, NM, GREAVES, MJ, JEWELL, R, PERRY, MWD, STOCKS, MJ and STONEHOUSE, JP, 2009. One-pot, three-component copper-catalysed 'click' triazole synthesis utilising the inexpensive, shelf-stable diazotransfer reagent imidazole-1-sulfonyl azide hydrochloride Synlett. 1391-1394

Content: GUILE, SD, ALCARAZ, L, BIRKINSHAW, TN, BOWERS, KC, EBDEN, MR, FURBER, M and STOCKS, MJ, 2009. Antagonists of the p2x(7) receptor. From lead identification to drug development Journal of Medicinal Chemistry. 52, 3123-3141

Content: BAZZI R, BRADSHAW TD, ROWLANDS JC, STEVENS MFG and BELL DR, 2009. 2-(4-Amino-3-Methylphenyl)-5-Fluorobenzothiazole Is A Ligand And Shows Species-Specific Partial Agonism Of The Aryl Hydrocarbon Receptor. Toxicology And Applied Pharmacology. 237(1), 102-10

Content: TURYANSKA, L., BRADSHAW, T.D., SHARPE, J., LI, M., MANN, S., THOMAS, N.R. and PATANÈ, A., 2009. The biocompatibility of apoferritin-encapsulated PbS quantum dots Small. 5(15), 1738-1741

Content: HOOLEY, ELIZABETH, PAPAGRIGORIOU, EVANGELOS, NAVDAEV, ALEXEI, PANDEY, AMIT V, CLEMETSON, JEANNINE M, CLEMETSON, KENNETH J and EMSLEY, JONAS, 2008. The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure. Biochemistry. 47(30), 7831-7

Content: ZIEGLER, WOLFGANG H, GINGRAS, ALEX R, CRITCHLEY, DAVID R and EMSLEY, JONAS, 2008. Integrin connections to the cytoskeleton through talin and vinculin. Biochemical Society transactions. 36(Pt 2), 235-9

Content: BAKER, J.G., PROUDMAN, R.G.W., HAWLEY, N.C., FISCHER, P.M. and HILL, S.J., 2008. Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human β1-adrenoceptor Molecular Pharmacology. 74(5), 1246-1260

Content: HUBER, K., PATEL, P., ZHANG, L., EVANS, H., WESTWELL, A.D., FISCHER, P.M., CHAN, S. and MARTIN, S., 2008. 2-[(1-Methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation Molecular Cancer Therapeutics. 7(1), 143-151

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