School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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WARNER,, VADOLIA,, LAUGHTON,, KERR, and DOUGHTY,, 2007. Modelling the restoration of wild-type dynamic behaviour in DeltaF508-CFTR NBD1 by 8-cyclopentyl-1,3-dipropylxanthine. Journal of Molecular Graphics and Modelling. 26, 691-699

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MCCARROLL, A.J., BURKE, M.B., LAUGHTON, C.A. and STEVENS, M.F.G., 2007. Quinols as novel therapeutic agents. Part 8 Applications of the Sonogashira route to thioredoxin-inhibitory indolyl-substituted quinols. Arkivoc. 2007(xi), 172-182

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WANG, HAO and LAUGHTON, CHARLES A, 2007. Molecular modelling methods for prediction of sequence-selectivity in DNA recognition. Methods (San Diego, Calif.). 42(2), 196-203

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PÉREZ, ALBERTO, MARCHÁN, IVÁN, SVOZIL, DANIEL, SPONER, JIRI, CHEATHAM, THOMAS E, LAUGHTON, CHARLES A and OROZCO, MODESTO, 2007. Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers. Biophysical Journal. 92(11), 3817-29

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NOY, AGNES, PÉREZ, ALBERTO, LAUGHTON, CHARLES A and OROZCO, MODESTO, 2007. Theoretical study of large conformational transitions in DNA: the B<-->A conformational change in water and ethanol/water. Nucleic Acids Research. 35(10), 3330-8

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HARRIS, S. A. and LAUGHTON, C. A., 2007. A simple physical description of DNA dynamics: quasi-harmonic analysis as a route to the configurational entropy JOURNAL OF PHYSICS CONDENSED MATTER. VOL 19(NUMB 7), 076103

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MIDDLETON,R, BRIDDON,S.J., CORDEAUX,Y., YATES,A.S., DALE,C.L., GEORGE,M., BAKER,J.G., HILL,S.J. and KELLAM,B., 2007. New Fluorescent Adenosine A(1)-Receptor Agonists That Allow Quantification of Ligand-Receptor Interactions in Microdomains of Single Living Cells. Journal of Medicinal Chemistry. 50(4), 782-793

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CORDEAUX, Y., BRIDDON,S.J., ALEXANDER, S.P.H., KELLAM, B. and HILL, S.J., 2007. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.The FASEB Journal FASEB. Available at: <http://www.fasebj.org/papbyrecent.dtl>

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DE BANK, P.A., HOU,Q., WARNER, R.M., WOOD, I.V., ALI, B.E., MACNEIL, S., KENDALL, D.A., KELLAM, B.K., SHAKESHEFF, K.M. and BUTTERY, L.D.K., 2007. Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking Biotechnology and Bioengineering. 97(6), 1617-1625

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WILLIAMS, P., WINZER, K., CHAN, W.C. and CAMARA, M., 2007. Look who's talking: communication and quorum sensing in the bacterial world Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 362, 1119-1134

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HAMZA, D, STOCKS, MJ, DECOR, A, PAIRAUDEAU, G and STONEHOUSE, JP, 2007. Synthesis of novel 2,6-diazaspiro[3.3]heptanes Synlett. 2584-2586

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STOCKS, MJ, HAMZA, D, PAIRAUDEAU, G, STONEHOUSE, JP and THORNE, PV, 2007. Concise synthesis of novel 2,6-diazaspiro [3.3] heptan-1-ones and their conversion into 2,6-diazaspiro[3.3]heptanes Synlett. 2587-2589

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ABUKHADER, MAJED M, HEAP, JOHN, DE MATTEIS, CRISTINA I, DOUGHTY, STEPHEN W, MINTON, NIGEL and PAOLI, MAX, 2007. Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 63(Pt 9), 746-50

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REID, SD, WILSON, C, DE MATTEIS, CI and LOVE, JB, 2007. Using chiral ligand substituents to promote the formation of dinuclear, double-stranded iron, manganese, and zinc mesocates European Journal of Inorganic Chemistry. 33, 5286-5293

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ATHANASIOU, ANDRIANI, CLARKE, ANNA B, TURNER, AMY E, KUMARAN, NETHIA M, VAKILPOUR, SARA, SMITH, PAUL A, BAGIOKOU, DIMITRA, BRADSHAW, TRACEY D, WESTWELL, ANDREW D, FANG, LIN, LOBO, DILEEP N and CONSTANTIN, 2007. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and biophysical research communications. 364(1), 131-7
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