Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: PARISOT, J., CAREY, S., BREUKINK, E., CHAN, W.C., NARBAD, A. and BONEV, B., 2008. Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic Antimicrobial Agents and Chemotherapy. 52(2), 612-618

Content: SANNA, MONICA, WHITE, PETER D and CHAN, WENG C, 2008. A macroporous polymer-supported cyclic anhydride for efficient sequestration of amines Tetrahedron Letters. 49(42), 6160-62

Content: MAYER, JOHN R., CHAN, WENG C. and REZVANI, ZAHRA N., 2008. MEK5 and related proteins as biomarkers of neurodegenerative diseases World Intellectual Property Organization WO 2008/132464-A2 11/01/2008 00:00:00

Content: PARKHOUSE, SUSAN M, GARNETT, MARTIN C and CHAN, WENG C, 2008. Targeting of polyamidoamine-DNA nanoparticles using the Staudinger ligation: attachment of an RGD motif either before or after complexation. Bioorganic and Medicinal Chemistry. 16(13), 6641-50

Content: STONEHOUSE, JP, CHEKMAREV, DS, IVANOVA, NV, LANG, S, PAIRAUDEAU, G, SMITH, N, STOCKS, MJ, SVIRIDOV, SI and UTKINA, LM, 2008. One-pot four-component reaction for the generation of pyrazoles and pyrimidines Synlett. 100-104

Content: BRADSHAW, T.D., STONE, E.L., TRAPANI, V., LEONG, C.-O., MATTHEWS, C.S., TE POELE, R. and STEVENS, M.F.G., 2008. Mechanisms of acquired resistance to 2-(4-amino-3-methylphenyl)benzothiazole in breast cancer cell lines Breast Cancer Research and Treatment. 110(1), 57-68

Content: CHEW, E.H., LU, J., BRADSHAW, T.D. and HOLMGREN, A., 2008. Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity FASEB Journal. 22(6), 2072-2083

Content: AIELLO, S., WELLS, G., STONE, E.L., KADRI, H., BAZZI, R., BELL, D.R., STEVENS, M.F.G., MATTHEWS, C.S., BRADSHAW, T.D. and WESTWELL, A.D., 2008. Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (Pmx 610, Nsc 721648) Journal of Medicinal Chemistry. 51(16), 5135-5139

Content: BRIGGS, G.S., MCEWAN, P.A., YU, J., MOORE, T., EMSLEY, J. and LLOYD, R.G., 2007. Ring structure of the Escherichia coli DNA binding protein RdgC associated with recombination and replication fork repair Journal of Biological Chemistry. 282(17), 12353-12357

Content: ROSADO, C.J., BUCKLE, A.M., LAW, R.H.P., BUTCHER.R.E., KAN, W.-T., BIRD, C.H., UNG, K., BROWNE, K.A., BARAN, K., BASHTANNYK-PUHALOVICH, T.A., FAUX, N.G., WONG, W., PORTER, C.J., PIKE, R.N., ELLISDON, A.M., PEARCE, M.C., BOTTOMLEY, S.P., EMSLEY, J., SMITH, A.I., ROSSJOHN J., HARTLAND, E.L., VOSKOBOINIK, I., TRAPANI, J.A., BIRD, P.I., DUNSTONE, M.A. and WHISSTOCK, J.C., 2007. A common fold mediates vertebrate defense and bacterial attack. Science. 317(5844), 1548-1551

Content: HOOLEY, E, MCEWAN, P A and EMSLEY, J, 2007. Molecular modeling of the prekallikrein structure provides insights into high-molecular-weight kininogen binding and zymogen activation. Journal of Thrombosis and Haemostasis: JTH. 5(12), 2461-6

Content: CRISTIAN BELLODI, KARIN KINDLE, FRANCESCA BERNASSOLA, ANDREA COSSARIZZA,DAVID DINSDALE, GERRY MELINO, DAVID M. HEERY AND PAOLO SALOMONI, 2007. A cytoplasmic PML mutant inhibits p53 function. Cell Cycle. 5(22), 2688-2692

Content: EL-SHEIKH, S., GREEN, A.R., RAKHA, E.A., AHMED, R.A., PAIS, E.C., GRAINGE, M.J., BALL, G.R., ROBERTSON, J.F., HEERY, D.M. and ELLIS, I.O., 2007. Global histone modifications in breast cancer tissue correlate with tumor phenotype, prognostic factors and patient outcome EJC Supplements. 5(3), 14-14

Content: DAVID M HEERY & PETER M FISCHER, 2007. Pharmacological targeting of lysine acetyltransferases in human disease: a progress report Drug Discovery Today. 12(1-2), 88-99

Content: EL-SHEIKH, S.E., GREEN, A.R., RAKHA, E.A., PAISH, E.C., HEERY, D.M. and ELLIS, I.O., 2007. Global histone modifications in breast cancer and their prognostic significance Modern Pathology. 20, 29A-30A

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