School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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WANG, S., ZHELEV, N.Z., DUFF, S. and FISCHER, P.M., 2006. Synthesis and biological activity of conjugates between paclitaxel and the cell delivery vector penetratin Bioorganic & Medicinal Chemistry Letters. 16(10), 2628-2631

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KRYSTOF, V., CANKAR, P., FRYSOVA, I., SLOUKA, J., KONTOPIDIS, G., DZUBAK, P., HAJDUCH, M., SROVNAL, J., DE AZEVEDO, W.F. JR, ORSAG, M., PAPRSKAROVA, M., ROLCIK, J., LATR, A., FISCHER, P.M. and STRNAD, M., 2006. 4-Arylazo-3,5-diamino-1H-pyrazole CDK inhibitors: SAR study, crystal structure in complex with CDK2, selectivity, and cellular effects Journal of Medicinal Chemistry. 49(22), 6500-6509

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ANDREWS, M.J.I., KONTOPIDIS, G., MCINNES, C., PLATER, A., INNES, L., COWAN, A., JEWSBURY, P. and FISCHER, P.M., 2006. REPLACE: A Strategy for Iterative Design of Cyclin-Binding Groove Inhibitors ChemBioChem. 7(12), 1909-1915

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THOMAS, M.P., MCINNES, C. and FISCHER, P.M., 2006. Protein structures in virtual screening: a case study with CDK2. Journal of Medicinal Chemistry. 49(1), 92-104

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FISCHER, P.M., 2006. Peptide, peptidomimetic, and small-molecule antagonists of the p53-HDM2 protein-protein interaction International Journal of Peptide Research and Therapeutics. 12(1), 3-19

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WINKLER, G.S.., MULDER, K.W., BARDWELL, V.J., KALKHOVEN, E. and TIMMERS, H.T.M., 2006. Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription The EMBO journal. 25(13), 3089-3099

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DREIJERINK, KOEN M A, MULDER, KLAAS W, WINKLER, G SEBASTIAAN, HÖPPENER, JO W M, LIPS, CORNELIS J M and TIMMERS, H TH MARC, 2006. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer research. 66(9), 4929-35

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LI, CHAN, YANAGISAWA, SACHIKO, MARTINS, BERTA M, MESSERSCHMIDT, ALBRECHT, BANFIELD, MARK J and DENNISON, CHRISTOPHER, 2006. Basic requirements for a metal-binding site in a protein: the influence of loop shortening on the cupredoxin azurin. Proceedings of the National Academy of Sciences of the United States of America. 103(19), 7258-63

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AL-ANIZY, M., HORLEY, N.J., KUO, C.-W.S., GILLETT, L.C., LAUGHTON, C.A., KENDALL, D., BARRETT, D.A., PARKER, T. and BELL, D.R., 2006. Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain FEBS Journal. 273(5), 936-947

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SHAH, M., WELLS, G., BRADSHAW, T. D., LAUGHTON, C. A., STEVENS, M. F. G. and WESTWELL, A. D., 2006. Antitubercular Properties of Substituted Hydroxycyclohexadienones LETTERS IN DRUG DESIGN AND DISCOVERY. VOL 3(NUMB 6), 419-423

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HALL, GARETH, SHAH, MANISH, MCEWAN, PAUL A, LAUGHTON, CHARLES, STEVENS, MALCOLM, WESTWELL, ANDREW and EMSLEY, JONAS, 2006. Structure of Mycobacterium tuberculosis thioredoxin C. Acta Crystallographica. Section D: Biological Crystallography. 62(Pt 12), 1453-7

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WELLS, GEOFF, MARTIN, CHRISTOPHER R H, HOWARD, PHILIP W, SANDS, ZARA A, LAUGHTON, CHARLES A, TIBERGHIEN, ARNAUD, WOO, CHI KIT, MASTERSON, LUKE A, STEPHENSON, MARISSA J, HARTLEY, JOHN A and JENKINS, TEREN, 2006. Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates. Journal of Medicinal Chemistry. 49(18), 5442-61

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MEYER, T, FERRER-COSTA, C, PEREZ, A, RUEDA, M, BIDON-CHANAL, A, LUQUE, FJ, LAUGHTON, CA and OROZCO, M, 2006. Essential dynamics: A tool for efficient trajectory compression and management Journal of Chemical Theory and Computation. 2, 251-258

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HEWETT, PW, DAFT, EL, LAUGHTON, CA, AHMAD, S, AHMED, A and MURRAY, JC, 2006. Selective inhibition of the human Tie-1 promoter with triplex-forming oligonucleotides targeted to Ets binding sites Molecular Medicine. 12, 8-16

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NIKJOO, H, GIRARD, P, CHARLTON, D E, HOFER, K G and LAUGHTON, C A, 2006. Auger electrons--a nanoprobe for structural, molecular and cellular processes. Radiation Protection Dosimetry. 122(1-4), 72-9
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School of Pharmacy

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