Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: HEWETT, PW, DAFT, EL, LAUGHTON, CA, AHMAD, S, AHMED, A and MURRAY, JC, 2006. Selective inhibition of the human Tie-1 promoter with triplex-forming oligonucleotides targeted to Ets binding sites Molecular Medicine. 12, 8-16

Content: NIKJOO, H, GIRARD, P, CHARLTON, D E, HOFER, K G and LAUGHTON, C A, 2006. Auger electrons--a nanoprobe for structural, molecular and cellular processes. Radiation Protection Dosimetry. 122(1-4), 72-9

Content: MURDOCK, S.E., TAI, K., NG, M.J., JOHNSTON, S., WU, B., FANGOHR, H., LAUGHTON, C.A., ESSEX, J.W. and SANSOM, M.S.P, 2006. Quality assurance for biomolecular simulations Journal of Chemical Theory and Computation. 2, 1477-1481

Content: POTZINGER, H., GERETTI, E., BRANDNER, B., WABITSCH, V., PICCININI, A. M., REK, A. and KUNGL, A. J., 2006. Developing chemokine mutants with improved proteoglycan affinity and knocked-out GPCR activity as anti-inflammatory recombinant drugs: Biochem Soc Trans Biochem Soc Trans. 34(Pt 3), 435-7

Content: WARFIELD, RACHEL, BARDELANG, PHILIP, SAUNDERS, HELEN, CHAN, WENG C, PENFOLD, CHRISTOPHER, JAMES, RICHARD and THOMAS, NEIL R, 2006. Internally quenched peptides for the study of lysostaphin: an antimicrobial protease that kills Staphylococcus aureus. Organic and Biomolecular Chemistry. 4(19), 3626-38

Content: CHAN, W.C., HIGTON, A. and DAVIES, J.S., 2006. Amino acids. In: DAVIES, J.S., ed., Amino acids, Peptides and Proteins 35. Cambridge University Press, Cambridge, UK. 1-73

Content: PEREZ, T, ERCILLA, G, CHAN, W C and HARO, I, 2006. Antigenicity of chimeric and cyclic synthetic peptides based on nonstructural proteins of GBV-C/HGV. Journal of Peptide Science. 12(4), 267-78

Content: BEURON, FABIENNE, DREVENY, INGRID, YUAN, XUEMEI, PYE, VALERIE E, MCKEOWN, CIARAN, BRIGGS, LOUISE C, CLIFF, MATTHEW J, KANEKO, YAYOI, WALLIS, RUSSELL, ISAACSON, RIVKA L, LADBURY, JOHN E and MATTHEWS, STEV, 2006. Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO Journal. 25(9), 1967-76

Content: UCHIYAMA, KEIJI, TOTSUKAWA, GO, PUHKA, MAIJA, KANEKO, YAYOI, JOKITALO, EIJA, DREVENY, INGRID, BEURON, FABIENNE, ZHANG, XIAODONG, FREEMONT, PAUL and KONDO, HISAO, 2006. p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis. Developmental Cell. 11(6), 803-16

Content: PYE, VALERIE E, DREVENY, INGRID, BRIGGS, LOUISE C, SANDS, CAROLINE, BEURON, FABIENNE, ZHANG, XIAODONG and FREEMONT, PAUL S, 2006. Going through the motions: the ATPase cycle of p97. Journal of Structural Biology. 156(1), 12-28

Content: MORTIMER, CATRIONA G, WELLS, GEOFFREY, CROCHARD, JEAN-PHILIPPE, STONE, ERICA L, BRADSHAW, TRACEY D, STEVENS, MALCOLM F G and WESTWELL, ANDREW D, 2006. Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. Journal of Medicinal Chemistry. 49(1), 179-85

Content: LION, CEDRIC J, MATTHEWS, CHARLES S, WELLS, GEOFFREY, BRADSHAW, TRACEY D, STEVENS, MALCOLM F G and WESTWELL, ANDREW D, 2006. Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols'). Bioorganic and Medicinal Chemistry Letters. 16(19), 5005-8

Content: FILLINGHAM, I., GINGRAS, A.R., PAPAGRIGORIOU, E., PATEL, B., EMSLEY, J., CRITCHLEY, D.R., ROBERTS, G.C.K. and BARSUKOV, I.L., 2005. A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head Structure. 13(1), 65-74

Content: GINGRAS, A.R., ZIEGLER, W.H., FRANK, R., BARSUKOV, I.L., ROBERTS, G.C.K., CRITCHLEY, D.R. and EMSLEY, J., 2005. Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod Journal of Biological Chemistry. 280(44), 37217-37224

Content: KINDLE, K.B., TROKE, P.J.F., COLLINS, H.M., MATSUDA, S., BOSSI, D., BELLODI, C., KALKHOVEN, E., SALOMONI, P., PELICCI, P.G., MINUCCI, S. and HEERY, D.M., 2005. MOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP function Molecular and Cellular Biology. 25(3), 988-1002

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