School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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ANDREWS, M.J.I., KONTOPIDIS, G., MCINNES, C., PLATER, A., INNES, L., COWAN, A., JEWSBURY, P. and FISCHER, P.M., 2006. REPLACE: A Strategy for Iterative Design of Cyclin-Binding Groove Inhibitors ChemBioChem. 7(12), 1909-1915

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THOMAS, M.P., MCINNES, C. and FISCHER, P.M., 2006. Protein structures in virtual screening: a case study with CDK2. Journal of Medicinal Chemistry. 49(1), 92-104

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FISCHER, P.M., 2006. Peptide, peptidomimetic, and small-molecule antagonists of the p53-HDM2 protein-protein interaction International Journal of Peptide Research and Therapeutics. 12(1), 3-19

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WINKLER, G.S.., MULDER, K.W., BARDWELL, V.J., KALKHOVEN, E. and TIMMERS, H.T.M., 2006. Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription The EMBO journal. 25(13), 3089-3099

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DREIJERINK, KOEN M A, MULDER, KLAAS W, WINKLER, G SEBASTIAAN, HÖPPENER, JO W M, LIPS, CORNELIS J M and TIMMERS, H TH MARC, 2006. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer research. 66(9), 4929-35

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LI, CHAN, YANAGISAWA, SACHIKO, MARTINS, BERTA M, MESSERSCHMIDT, ALBRECHT, BANFIELD, MARK J and DENNISON, CHRISTOPHER, 2006. Basic requirements for a metal-binding site in a protein: the influence of loop shortening on the cupredoxin azurin. Proceedings of the National Academy of Sciences of the United States of America. 103(19), 7258-63

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BEURON, FABIENNE, DREVENY, INGRID, YUAN, XUEMEI, PYE, VALERIE E, MCKEOWN, CIARAN, BRIGGS, LOUISE C, CLIFF, MATTHEW J, KANEKO, YAYOI, WALLIS, RUSSELL, ISAACSON, RIVKA L, LADBURY, JOHN E and MATTHEWS, STEV, 2006. Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO Journal. 25(9), 1967-76

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UCHIYAMA, KEIJI, TOTSUKAWA, GO, PUHKA, MAIJA, KANEKO, YAYOI, JOKITALO, EIJA, DREVENY, INGRID, BEURON, FABIENNE, ZHANG, XIAODONG, FREEMONT, PAUL and KONDO, HISAO, 2006. p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis. Developmental Cell. 11(6), 803-16

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PYE, VALERIE E, DREVENY, INGRID, BRIGGS, LOUISE C, SANDS, CAROLINE, BEURON, FABIENNE, ZHANG, XIAODONG and FREEMONT, PAUL S, 2006. Going through the motions: the ATPase cycle of p97. Journal of Structural Biology. 156(1), 12-28

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POTZINGER, H., GERETTI, E., BRANDNER, B., WABITSCH, V., PICCININI, A. M., REK, A. and KUNGL, A. J., 2006. Developing chemokine mutants with improved proteoglycan affinity and knocked-out GPCR activity as anti-inflammatory recombinant drugs: Biochem Soc Trans Biochem Soc Trans. 34(Pt 3), 435-7

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SEDMAN, V.L., ALLEN, S., CHAN, W.C., DAVIES, M.C., ROBERTS, C.J., TENDLER, S.J.B. and WILLIAMS, P.M., 2005. Atomic force microscopy study of human amylin (20-29) fibrils Protein and Peptide Letters. 12(1), 79-83

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GARDINER, L., COYLE, B.J, CHAN, W.C and SOULTANAS, P., 2005. Discovery of antagonist peptides against bacterial helicase-primase interaction in B. stearothermophilus by reverse yeast three-hybrid. Chemistry & Biology. 12(5), 595-604

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SEDMAN, V.L., ALLEN, S., CHAN, W.C., KELLAM, B. and TENDLER S.J.B., 2005. Functionalizing human amylin (20-29) fibrils FEBS Journal. 272, 517-518

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SEVILLE, LUCY L, SHAH, NITA, WESTWELL, ANDREW D and CHAN, WENG C, 2005. Modulation of pRB/E2F functions in the regulation of cell cycle and in cancer. Current Cancer Drug Targets. 5(3), 159-70

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ZHELEVA, D.L., FISCHER, P.M., MCINNES, C., ANDREWS, M.J.I., CHAN, W.C. and ATKINSON, G.E., 2005. Cyclin binding peptides, and their use in drug screening assays WO 2005/040802 A3 05/06/2005 00:00:00
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