School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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LAUGHTON, C. A., GRINDON, C., GIRARD, P. and NIKJOO, H., 2004. The mysteries of telomere structure and recognition: could radioprobing help? International Journal of Radiation Biology. VOL 80(NO 11-12), 805-812

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PICCININI, A. M., SCHMID, M. G., PAJPANOVA, T., PANCHEVA, S., GRUEVA, E. and GUBITZ, G., 2004. Chiral separation of natural and unnatural amino acid derivatives by micro-HPLC on a Ristocetin A stationary phase: J Biochem Biophys Methods J Biochem Biophys Methods. 61(1-2), 11-21

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BRIDDON, S.J., MIDDLETON, R.J., CORDEAUX, Y., FLAVIN, F.M., WEINSTEIN, J.A., GEORGE, M.W., KELLAM, B. and HILL, S.J., 2004. Quantitative analysis of the formation and diffusion of A1-adenosine receptor-antagonist complexes in single living cells Proceedings of the National Academy of Sciences of the United States of America. 101(13), 4673-4678

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BRIDDON, S.J., MIDDLETON, R.J., YATES, A.S., GEORGE, M.W., KELLAM, B. and HILL, S.J., 2004. Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level Faraday Discussions. 126, 197-207

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SLEEMAN, MARK C, SMITH, PAUL, KELLAM, BARRIE, CHHABRA, SIRI RAM, BYCROFT, BARRIE W and SCHOFIELD, CHRISTOPHER J, 2004. Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC). ChemBioChem. 5(6), 879-82

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CHAN, W.C., COYLE, B.J. and WILLIAMS, P., 2004. Virulence regulation and quorum sensing in staphylococcal infections: competitive AgrC antagonists as quorum sensing inhibitors Journal of Medicinal Chemistry. 47(19), 4633-41

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MIDDLETON,R.J., MELLOR,S.L., CHHABRA,S.R., BYCROFT,B.W. and CHAN,W.C., 2004. Expedient synthesis of a novel class of pseudoaromatic amino acids: tetrahydroindazol-3-yl- and tetrahydrobenzisoxazol-3-ylalanine derivatives Tetrahedron Letters. 45(6), 1237-1242

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DREVENY, INGRID, KONDO, HISAO, UCHIYAMA, KEIJI, SHAW, ANTHONY, ZHANG, XIAODONG and FREEMONT, PAUL S, 2004. Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47. EMBO Journal. 23(5), 1030-9

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YUAN, XUEMEI, SIMPSON, PETER, KONDO, HISAO, MCKEOWN, CIARAN, DREVENY, INGRID, ZHANG, XIAODONG, FREEMONT, PAUL S and MATTHEWS, STEPHEN, 2004. Complete backbone resonance assignments of p47: the 41kDa adaptor protein of the AAA ATPase p97. Journal of Biomolecular NMR. 28(3), 309-10

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DREVENY, I, PYE, V E, BEURON, F, BRIGGS, L C, ISAACSON, R L, MATTHEWS, S J, MCKEOWN, C, YUAN, X, ZHANG, X and FREEMONT, P S, 2004. p97 and close encounters of every kind: a brief review. Biochemical Society Transactions. 32(Pt 5), 715-20

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YUAN, XUEMEI, SIMPSON, PETER, MCKEOWN, CIARAN, KONDO, HISAO, UCHIYAMA, KEIJI, WALLIS, RUSSELL, DREVENY, INGRID, KEETCH, CATHERINE, ZHANG, XIAODONG, ROBINSON, CAROL, FREEMONT, PAUL and MATTHEWS, STEPHEN, 2004. Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97. EMBO Journal. 23(7), 1463-73

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STOCKS, MJ, CHESHIRE, DR and REYNOLDS, R, 2004. Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles Organic Letters. 6(17), 2969-2971

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LEONG, C.O., SUGGITT, M., SWAINE, D.J., BIBBY, M.C., STEVENS, M.F.G. and BRADSHAW, T.D., 2004. In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazoles. Molecular Cancer Therapeutics. 3(12), 1565-1575

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FICHTNER, I., MONKS, A., HOSE, C., STEVENS, M.F.G. and BRADSHAW, T.D., 2004. The experimental antitumor agents Phortress and Doxorubicin are equiactive against human-derived breast carcinoma xenograft models Breast Cancer Research and Treatment. 87(1), 97-107

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BRANTLEY, E., TRAPANI, V., ALLEY, M.C., HOSE, C.D., BRADSHAW, T.D., STEVENS, M.F.G., SAUSVILLE, E.A. and STINSON, S.F., 2004. Fluorinated 2-(4-amino-3-methylphenyl)benzothiazoles induce CYP1A1 expression, become metabolized, and bind to macromolecules in sensitive human cancer cells Drug Metabolism and Disposition. 32(12), 1392-1401
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