School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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BRADSHAW, T D and WESTWELL, A D, 2004. The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate. Current Medicinal Chemistry. 11(8), 1009-21

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HIORNS, L R, BRADSHAW, T D, SKELTON, L A, YU, Q, KELLAND, L R and LEYLAND-JONES, B, 2004. Variation in RNA expression and genomic DNA content acquired during cell culture. British Journal of Cancer. 90(2), 476-82

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SHEPPARD, H M, MATSUDA, S, HARRIES, J C, KINDLE, K B and HEERY, D M, 2003. Transcriptional activation by estrogen receptor (ERalpha) and steroid receptor coactivator (SRC1) involves distinct mechanisms in yeast and mammalian cells. Journal of Molecular Endocrinology. 30(3), 411-22

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COULTHARD, V. H., MATSUDA, S. and HEERY, D. M., 2003. An Extended LXXLL Motif Sequence Determines the Nuclear Receptor Binding Specificity of TRAP220 Journal of Biological Chemistry. VOL 278(PART 13), 10942-10951

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WU, S.Y., MCNAE, I., KONTOPIDIS, G., MCCLUE, S.J., MCINNES, C., STEWART, K.J., WANG, S., ZHELEVA, D.I., MARRIAGE, H., LANE, D.P., TAYLOR, P., FISCHER, P.M. and WALKINSHAW, M.D., 2003. Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop Structure. 11(4), 399-410

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KONTOPIDIS, G., ANDREWS, M.J.I., MCINNES, C., COWAN, A., POWERS, H., INNES, L., PLATER, A., GRIFFITHS, G., PATERSON, D., ZHELEVA, D.I., LANE, D.P., GREEN, S., WALKINSHAW, M.D. and FISCHER, P.M., 2003. Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange. Structure. 11(12), 1537-1546

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SAREK, J., KLINOT, J., DZUBAK, P., KLINOTOVA, E., NOSKOVA, V., KRECEK, V., KORINKOVA, G., THOMSON, J.O., JANOST'AKOVA, A., WANG, S., PARSONS, S., FISCHER, P.M., ZHELEV, N.Z. and HAJDUCH, M., 2003. New Lupane Derived Compounds with Pro-Apoptotic Activity in Cancer Cells: Synthesis and Structure-Activity Relationships Journal of Medicinal Chemistry. VOL 46(PART 25), 5402-5415

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FISCHER, P.M., 2003. Diketopiperazines in peptide and combinatorial chemistry. Journal of Peptide Science. 9(1), 9-35

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FISCHER, P.M., ENDICOTT, J. and MEIJER, L., 2003. Cyclin-dependent kinase inhibitors. Progress in Cell Cycle Research. 5, 235-248

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MCINNES, C., ANDREWS, M.J.I., ZHELEVA, D.I., LANE, D.P. and FISCHER, P.M., 2003. Peptidomimetic design of CDK inhibitors targeting the recruitment site of the cyclin subunit. Current Medicinal Chemistry - Anti-Cancer Agents. 3(1), 57-69

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FISCHER, P.M. and GIANELLA-BORRADORI, A., 2003. CDK inhibitors in clinical development for the treatment of cancer. Expert Opinion on Investigational Drugs. 12(6), 955-970

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FISCHER, P.M., BELL, G., MIDGLEY, C., SLEIGH, R. and GLOVER, D.M., 2003. Cell cycle target validation: approaches and successes Targets. 2(4), 154-161

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FISCHER, P.M., 2003. The Design, Synthesis and Application of Stereochemical and Directional Peptide Isomers: A Critical Review Current Protein & Peptide Science. VOL 4(NUMB 5), 339-356

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FISCHER, P.M., 2003. CNIO cancer conference: targeted search for anticancer drugs. Expert Opinion on Investigational Drugs. 12(6), 1039-1044

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FISCHER, P.M., 2003. CDK versus GSK-3 inhibition: a purple haze no longer? Chemistry & Biology. 10(12), 1144-1146
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School of Pharmacy

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