School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content
PALLIS, MONICA, BRADSHAW, TRACEY D, WESTWELL, ANDREW D, GRUNDY, MARTIN, STEVENS, MALCOLM F G and RUSSELL, NIGEL, 2003. Induction of apoptosis without redox catastrophe by thioredoxin-inhibitory compounds. Biochemical Pharmacology. 66(9), 1695-705

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WELLS, G., BERRY, J.M., BRADSHAW, T.D., BURGER, A.M., SEATON, A., WANG, B., WESTWELL, A.D. and STEVENS, M.F.G., 2003. 4-Substituted 4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines Journal of Medicinal Chemistry. 46(4), 532-541

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HUTCHINSON, IAN, BRADSHAW, TRACEY D, MATTHEWS, CHARLES S, STEVENS, MALCOLM F G and WESTWELL, ANDREW D, 2003. Antitumour benzothiazoles. Part 20: 3'-cyano and 3'-alkynyl-substituted 2-(4'-aminophenyl)benzothiazoles as new potent and selective analogues. Bioorganic and Medicinal Chemistry Letters. 13(3), 471-4

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PALLIS, M., BRADSHAW, T.D., WESTWELL, A.D., GRUNDY, M., STEVENS, M.F. and RUSSELL, N.H., 2003. The thioredoxin inhibitor AW464 and the dithiol oxidant diamide induce apoptosis without accumulation of reactive oxygen species Leukemia. 17, P25

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LEONG, C-O, GASKELL, M, MARTIN, E A, HEYDON, R T, FARMER, P B, BIBBY, M C, COOPER, P A, DOUBLE, J A, BRADSHAW, T D and STEVENS, M F G, 2003. Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo. British Journal of Cancer. 88(3), 470-7

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UFF, S., CLEMETSON, J.M., HARRISON, T., CLEMETSON, K.J. and EMSLEY, J., 2002. Crystal structure of the platelet glycoprotein Ibα N-terminal domain reveals an unmasking mechanism for receptor activation Journal of Biological Chemistry. 277(38), 35657-35663

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GIRAUD, SANDRINE, BIENVENU, FRéDéRIC, AVRIL, SYLVIE, GASCAN, HUGUES, HEERY, DAVID M and COQUERET, OLIVIER, 2002. Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. Journal of Biological Chemistry. 277(10), 8004-11

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ATKINSON, G.E., COWAN, A., MCINNES, C., ZHELEVA, D.I., FISCHER, P.M. and CHAN, W.C., 2002. Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-site: structural variants of the C-terminal Phe. Bioorganic and Medicinal Chemistry Letters. 12(18), 2501-2505

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MCCLUE, S.J., BLAKE, D., CLARKE, R., COWAN, A., CUMMINGS, L., FISCHER, P.M., MACKENZIE, M., MELVILLE, J., STEWART, K., WANG, S., ZHELEV, N., ZHELEVA, D. and LANE, D.P., 2002. In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine). International Journal of Cancer. 102(5), 463-468

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CHAN, W.C., ATKINSON, G.E., COWAN, A., MCINNES, C. and FISCHER, P.M., 2002. p21(WAF1)-derived octapeptide inhibitors of CDK-cyclin complex: The effect of structural variants of the C-terminal Phe residue Journal of Peptide Science. 8, S146

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ZHELEVA, D.I., MCINNES, C., GAVINE, A., ZHELEV, N.Z., FISCHER, P.M. and LANE, D.P., 2002. Highly potent p21WAF1-derived peptide inhibitors of CDK-mediated pRb phosphorylation: Delineation and structural insight into their interactions with cyclin A Journal of Peptide Research. 60(5), 257-270

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ORNING, L., FISCHER, P.M., HU, C.-K., AGNER, E., ENGEBRETSEN, M., HUSBYN, M., PETERSEN, L.B., ORVIM, U., LLINAS, M. and SAKARIASSEN, K.S., 2002. A Cyclic Pentapeptide Derived from the Second EGF-Like Domain of Factor VII Is an Inhibitor of Tissue Factor Dependent Coagulation and Thrombus Formation Thrombosis and Haemostasis. VOL 87(PART 1), 13-21

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DAVIDSON-MONCADA, J.K., LOPEZ-LLUCH, G., SEGAL, A.W. and DEKKER, L.V., 2002. Involvement of protein kinase D in Fcγ-receptor activation of the NADPH oxidase in neutrophils Biochemical Journal. 363(1), 95-103

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WINKLER, G.S., KRISTJUHAN, A., ERDJUMENT-BROMAGE, H., TEMPST, P. and SVEJSTRUP, J.Q., 2002. Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo Proceedings of the National Academy of Sciences of the United States of America. 99(6), 3517-3522
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