School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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WESTWELL, A.D., WELLS, G., BERRY, J.M., BRADSHAW, T.D., BURGER, A.M., MATTHEWS, C.S. and STEVENS, M.F., 2002. Synthesis of heteroaromatic quinols, novel agents with selective activity clustered in colon and renal cell lines Proceedings of the American Association for Cancer Research. 43, 1034

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STEVENS, M.F., WELLS, G., BRADSHAW, T.D., WESTWELL, A.D. and HOLBECK, S.L., 2002. The use of the COMPARE algorithm to guide mechanistic studies on novel antitumour agents Proceedings of the American Association for Cancer Research. 43, 4731

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MUKHERJEE, A., MARTIN, S., BRADSHAW, T.D., WESTWELL, A.D. and CARMICHAEL, J., 2002. In vitro antitumour and antiangiogenic activity of AW 464 (NSC 706704), a novel quinol British Journal of Cancer. 86(1), S108-S109

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BRADSHAW, T D, CHUA, M-S, BROWNE, H L, TRAPANI, V, SAUSVILLE, E A and STEVENS, M F G, 2002. In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles. British Journal of Cancer. 86(8), 1348-54

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BRADSHAW, T D, TRAPANI, V, VASSELIN, D A and WESTWELL, A D, 2002. The aryl hydrocarbon receptor in anticancer drug discovery: friend or foe? Current Pharmaceutical Design. 8(27), 2475-90

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BRADSHAW, TRACEY D, BIBBY, MICHAEL C, DOUBLE, JOHN A, FICHTNER, IDUNA, COOPER, PATRICIA A, ALLEY, MICHAEL C, DONOHUE, SUSAN, STINSON, SHERMAN F, TOMASZEWJSKI, JOSEPH E, SAUSVILLE, EDWARD A and STEVENS, MALCOLM F G, 2002. Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles. Molecular Cancer Therapeutics. 1(4), 239-46

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LOAIZA-PÉREZ, ANDREA I, TRAPANI, VALENTINA, HOSE, CURTIS, SINGH, SHEO S, TREPEL, JANE B, STEVENS, MALCOLM F G, BRADSHAW, TRACEY D and SAUSVILLE, EDWARD A, 2002. Aryl hydrocarbon receptor mediates sensitivity of MCF-7 breast cancer cells to antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole. Molecular Pharmacology. 61(1), 13-9

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HOLMES, V. E., QI, F. M., LAUGHTON, C. A., BELL, D. R., SHAW, P. N. and BARRETT, D. A., 2002. Structure-activity relationships of CYP4A1 Toxicology. VOL 178(NO 1), 43

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FAN, M. Q., HOLMES, V., LAUGHTON, C. A., SHAW, P. N., BARRETT, D. A. and BELL, D. R., 2002. Study of the residues in conserved C-helix region of CYP4A1: bacterial expression and mutagenesis Toxicology. VOL 178(NO 1), 42

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DRYDEN, I.L., KUME, A., LE, H., WOOD, A.T.A. and LAUGHTON, C.A., 2002. Size-and-shape analysis of DNA molecular dynamics simulations In: Statistics of Large Datasets. 23-26

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MISSAILIDIS,S., STANSLAS,J., MODI,C., ELLIS,M.J., ROBINS,R.A., LAUGHTON,C.A. and STEVENS,M.F.G, 2002. Antitumour polycyclic acridines: Part 12. Physical and biological properties of 8,13-diethyl-6-methylquino[4,3,2-k]acridinium iodide: A lead compound in anticancer drug design Oncology Research. 13(3), 175-189

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HEALD, ROBERT A, MODI, CHETNA, COOKSON, JENNY C, HUTCHINSON, IAN, LAUGHTON, CHARLES A, GOWAN, SHARON M, KELLAND, LLOYD R and STEVENS, MALCOLM F G, 2002. Antitumor polycyclic acridines. 8.(1) Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts. Journal of Medicinal Chemistry. 45(3), 590-7

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CHAN, DAVID C M, LAUGHTON, CHARLES A, QUEENER, SHERRY F and STEVENS, MALCOLM F G, 2002. Structural studies on bioactive compounds. Part 36: design, synthesis and biological evaluation of pyrimethamine-based antifolates against Pneumocystis carinii. Bioorganic and Medicinal Chemistry. 10(9), 3001-10

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SHAKESHEFF, K.M., SILVA, M., HOWDLE, S.M., SALEM, A.K., ROSE, F.R., WHITAKER, M.J., WOOD, I., DE BANK, P., KENDALL, D.A. and KELLAM, B., 2002. Delivering protein and cell therapeutics for tissue regeneration In: International Symposium on Recent Advances in Drug Delivery Systems.

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SMITH, P., CHHABRA, S.R., KELLAM, B. and BYCROFT, B.W., 2002. Synthetic and biotransformations studies on trans-(3S, 5S)-1-carbapenam-3-carboxylic acid In: Third International Meeting. 33
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