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Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: HARRIS, S A., GAVATHIOTIS, E., SEARLE, M S., OROZCO, M. and LAUGHTON, C A., 2001. Cooperativity in drug-DNA recognition: a molecular dynamics study Journal of the American Chemical Society. 123(50), 12658-12663

Content: BOSTOCK-SMITH, C E, HARRIS, S A, LAUGHTON, C A and SEARLE, M A, 2001. Induced fit DNA recognition by a minor groove binding analogue of Hoechst 33258: fluctuations in DNA A tract structure investigated by NMR and molecular dynamics simulations. Nucleic Acids Research. 29(3), 693-702

Content: CHAN, D C, LAUGHTON, C A, QUEENER, S F and STEVENS, M F, 2001. Structural studies on bioactive compounds. 34. Design, synthesis, and biological evaluation of triazenyl-substituted pyrimethamine inhibitors of Pneumocystis carinii dihydrofolate reductase. Journal of Medicinal Chemistry. 44(16), 2555-64

Content: BRADSHAW, T.D., BROWNE, H.L., HUTCHINSON, I., LAUGHTON, C.A., LEONG, C.O., OBRIEN, S., STEVENS, M.F., TRAPANI, V. and WESTWELL, A.D., 2001. Mechanistic studies and evaluation of clinical markers for phortress, a new agent for clinical trials British Journal of Cancer. 85, 272

Content: CHHABRA, S. R., PAREKH, H., KHAN, A. N., BYCROFT, B. W. and KELLAM, B., 2001. A Dde-based carboxy linker for solid-phase synthesis Tetrahedron Letters. VOL 42(PART 11), 2189-2192

Content: PAREKH, H., CHHABRA, S.R., BYCROFT, B.W. and KELLAM, B., 2001. Synthesis, evaluation and solid-phase applications of a Dde-based carboxy linker In: American Peptide Symposium. 145

Content: WARD, P., CHHABRA, S.R. and KELLAM, B., 2001. Nsuper^α-Dmc protected amino acids: Hydrogenolysis and acid stable acceptors for α-glycosyl-1-O-amino acid synthesis In: American Peptide Symposium. P204

Content: QUIRK, R.A., CHAN, W.C., DAVIES, M.C., TENDLER, S.J.B. and SHAKESHEFF, K.M., 2001. Poly(L-lysine)-GRGDS as a biomimetic surface modifier for poly(lactic acid). Biomaterials. 22(8), 865-72

Content: MCDOWELL, P., AFFAS, Z., REYNOLDS, C., HOLDEN, M.T.G., WOOD, S.J., SAINT, S., COCKAYNE, A., HILL, P.J., DODD, C.E.R., BYCROFT, B.W., CHAN, W.C. and WILLIAMS, P., 2001. Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus Molecular Microbiology. 41(2), 503-512

Content: QAZI, S.N.A., COUNIL, E., MORRISSEY, J., REES, C.E.D., COCKAYNE, A., WINZER, K., CHAN, W.C., WILLIAMS, P. and HILL, P.J., 2001. agr expression precedes escape of internalized Staphylococcus aureus from the host endosome Infection and Immunity. 69(11), 7074-7082

Content: CUNLIFFE, R.N., ROSE, F.R.A.J., KEYTE, J., ABBERLEY, L., CHAN, W.C. and MAHIDA, Y.R., 2001. Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease Gut: Journal of the British Society of Gastroenterology. 48(2), 176-185

Content: QUIRK, R.A., DAVIES, M.C., TENDLER, S.J.B., CHAN, W.C. and SHAKESHEFF, K.M., 2001. Controlling biological interactions with poly(lactic acid) by surface entrapment modification Langmuir. 17(9), 2817-2820

Content: CHAN, W.C., MELLOR, S.L. and ATKINSON, G.E., 2001. N-Fmoc-aminooxy-2-chlorotrityl polystyrene resin for high throughput synthesis of hydroxamic acids Solid-phase Organic Syntheses. 1, 85-99

Content: DREVENY, I, GRUBER, K, GLIEDER, A, THOMPSON, A and KRATKY, C, 2001. The hydroxynitrile lyase from almond: a lyase that looks like an oxidoreductase. Structure. 9(9), 803-15

Content: JOHNSON, TIM, CHESHIRE, DAVID R, STOCKS, MICHAEL J and THURSTON, VICKY T, 2001. A Carbonyl Ylide Approach to Substituted Furans: Synlett Synlett. 0646-0648

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