Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: FENN, SAMUEL, DUBERN, JEAN-FREDERIC, STOCKS, MICHAEL, ELMSLEY, JONAS and CAMARA, MIGUEL, 2019. Identification of a nitrite reductase in Pseudomonas aeruginosa as a potential antimicrobial target Access Microbiology. 1(1A), 635

Content: ASHRAF S, RADHI M, GOWLER P, BURSTON JJ, GANDHI RD, THORN GJ, PICCININI AM, WALSH DA, CHAPMAN V and DE MOOR CH, 2019. The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis. Scientific reports. 9(1), 4696

Content: SANCHEZ J, LANE JR, CANALS M and STONE MJ, 2019. Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1. International journal of molecular sciences. 20(10),

Content: LEAVER DJ, CLEARY B, NGUYEN N, PRIEBBENOW DL, LAGIAKOS HR, SANCHEZ J, XUE L, HUANG F, SUN Y, MUJUMDAR P, MUDUDUDDLA R, VARGHESE S, TEGUH S, CHARMAN SA, WHITE KL, KATNENI K, CUELLAR M, STRASSER JM, DAHLIN JL, WALTERS MA, STREET IP, MONAHAN BJ, JARMAN KE, SABROUX HJ, FALK H, CHUNG MC, HERMANS SJ, PARKER MW, THOMAS T and BAELL JB, 2019. Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A. Journal of medicinal chemistry. 62(15), 7146-7159

Content: JISOOK LEE, NATALIE B. VINH, NYSSA DRINKWATER, WEI YANG, KOMAGAL KANNAN SIVARAMAN, LUKE S. SCHEMBRI, MICHELLE GAZDIK, PETER M. GRIN, GEORGINA S. BUTLER, CHRISTOPHER M. OVERALL, SUSAN A. CHARMAN, SHEENA MCGOWAN* and PETER J. SCAMMELLS*, 2019. Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions Journal of Medicinal Chemistry. 62(15), 7185-7209

Content: LUKE S. SCHEMBRI, JONAS ERIKSSON and LUKE R. ODELL*, 2019. Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation The Journal of Organic Chemistry. 84(11), 6970-6981

Content: NG, V., KUEHNE, S. A. and CHAN, W.C., 2018. Rational design and synthesis of modified teixobactin analogues: in vitro antibacterial activity against Staphylococcus aureus, Propionibacterium acnes and Pseudomonas aeruginosa Chemistry - A European Journal. 24(36), 9136-9147

Content: CHAN, W.C., GENAPATHY, S. and YANG, L., 2018. Antibacterial compounds WO 2018/167506 A1 09/20/2018 00:00:00

Content: ZAMBERLAN, F., TURYANSKA, L., PATANE, A., LIU, Z., WILLIAMS, H. E. L., FAY, M. W., CLARKE, P. A., IMAMURA, Y., JIN, T., BRADSHAW, T. D., THOMAS, N. R. and GRABOWSKA, A. M., 2018. Stable DHLA-PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging: Journal of Materials Chemistry B Journal of Materials Chemistry B. 6(4), 550-555

Content: BIN BREAK, MOHAMMED KHALED, HOSSAN, MD SHAHADAT, KHOO, YIVONN, QAZZAZ, MOHANNAD EMAD, AL-HAYALI, MOHAMMED Z. K., CHOW, SEK CHUEN, WIART, CHRISTOPHE, BRADSHAW, TRACEY D., COLLINS, HILARY and KHOO, TENG-JIN, 2018. Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway FITOTERAPIA. 125, 161-173

Content: SANTOS, MARILIA S., NORTCLIFFE, ANDREW, LEWIS, WILLIAM, BRADSHAW, TRACEY D. and MOODY, CHRISTOPHER J., 2018. Synthesis of Highly Substituted 1,2-Diazetidin-3-ones, Small-Ring Scaffolds for Drug Discovery CHEMISTRY-A EUROPEAN JOURNAL. 24(33), 8325-+

Content: COUSIN, DAVID, HUMMERSONE, MARC G., BRADSHAW, TRACEY D., ZHANG, JIHONG, MOODY, CHRISTOPHER J., FOREITER, MAGDALENA B., SUMMERS, HELEN S., LEWIS, WILLIAM, WHEELHOUSE, RICHARD T. and STEVENS, MALCOLM F. G., 2018. Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position MEDCHEMCOMM. 9(3), 545-553

Content: CITOSSI, FRANCESCA, SMITH, THOMAS, LEE, JONG BONG, SEGAL, JOEL, GERSHKOVICH, PAVEL, STOCKS, MICHAEL J., BRADSHAW, TRACEY D., KELLAM, BARRIE and MARLOW, MARIA, 2018. Self-Assembling Benzothiazole-Based Gelators: A Mechanistic Understanding of in Vitro Bioactivation and Gelation MOLECULAR PHARMACEUTICS. 15(4), 1578-1586

Content: LEE JB, ZGAIR A, MALEC J, KIM TH, KIM MG, ALI J, QIN C, FENG W, CHIANG M, GAO X, VORONIN G, GARCES AE, LAU CL, CHAN TH, HUME A, MCINTOSH TM, SOUKARIEH F, AL-HAYALI M, CIPOLLA E, COLLINS HM, HEERY DM, SHIN BS, YOO SD, KAGAN L, STOCKS MJ, BRADSHAW TD, FISCHER PM and GERSHKOVICH P, 2018. Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system. Journal of controlled release : official journal of the Controlled Release Society. 286, 10-19

Content: SMEDLEY, CHRISTOPHER J., STANLEY, PAUL A., QAZZAZ, MOHANNAD E., PROTA, ANDREA E., OLIERIC, NATACHA, COLLINS, HILARY, EASTMAN, HARRY, BARROW, ANDREW S., LIM, KUAN-HON, KAM, TOH-SEOK, SMITH, BRIAN J., DUIVENVOORDEN, HENDRIKA M., PARKER, BELINDA S., BRADSHAW, TRACEY D., STEINMETZ, MICHEL O. and MOSES, JOHN E., 2018. Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site SCIENTIFIC REPORTS. 8,

Publications