Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: CHAN, W.C., GENAPATHY, S. and YANG, L., 2018. Antibacterial compounds WO 2018/167506 A1 09/20/2018 00:00:00

Content: RIEGLER-BERKET L, LEITMEIER A, ASCHAUER P, DREVENY I and OBERER M, 2018. Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures. Biochimica et biophysica acta. 1863(7), 679-687

Content: SPILIOTOPOULOS A, BLOKPOEL FERRERAS L, DENSHAM RM, CAULTON SG, MADDISON BC, MORRIS JR, DIXON JE, GOUGH KC and DREVENY I, 2018. Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11. The Journal of biological chemistry. 294(2), 424-436

Content: SOUKARIEH, F., OTON, E.V., DUBERN, J.-F., GOMES, J., HALLIDAY, N., DE PILAR CRESPO, M., RAMÍREZ-PRADA, J., INSUASTY, B., ABONIA, R., QUIROGA, J., HEEB, S., WILLIAMS, P., STOCKS, M.J. and CÁMARA, M., 2018. In silico and in vitro-guided identification of inhibitors of alkylquinolone-dependent quorum sensing in pseudomonas aeruginosa: Molecules Molecules. 23,

Content: CITOSSI, FRANCESCA, SMITH, THOMAS, LEE, JONG BONG, SEGAL, JOEL, GERSHKOVICH, PAVEL, STOCKS, MICHAEL JOHN, BRADSHAW, TRACEY D, KELLAM, BARRIE and MARLOW, MARIA, 2018. Self-assembling benzothiazole-based gelators: a mechanistic understanding of in vitro bioactivation and gelation: Molecular Pharmaceutics Molecular Pharmaceutics. acs.molpharmaceut.7b01106

Content: SKILLING, KATHRYN J., STOCKS, MICHAEL J., KELLAM, BARRIE, ASHFORD, MARIANNE, BRADSHAW, TRACEY, BURROUGHS, LAURENCE and MARLOW, MARIA, 2018. Nucleoside Based Self-Assembling Drugs for Localized Drug Delivery ChemMedChem.

Content: CONROY, SEAN, KINDON, NICHOLAS D., GLENN, JACQUELINE, STODDART, LEIGH A., LEWIS, RICHARD JAMES, HILL, STEPHEN J., KELLAM, BARRIE and STOCKS, MICHAEL JOHN, 2018. Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y 2 Receptor Based on AR-C118925 Journal of Medicinal Chemistry. 61(7), 3089-3113

Content: SOU, TOMAS, KUKAVICA-IBRULJ, IRENA, SOUKARIEH, FADI, HALLIDAY, NIGEL, LEVESQUE, ROGER C, WILLIAMS, PAUL, STOCKS, MICHAEL, CAMARA, MIGUEL, FRIBERG, LENA E and BERGSTROM, CHRISTEL A S, 2018. Model-based drug development in pulmonary delivery: Pharmacokinetic analysis of novel drug candidates for treatment of Pseudomonas aeruginosa lung infection. Journal of pharmaceutical sciences.

Content: SOUKARIEH, FADI, WILLIAMS, PAUL, STOCKS, MICHAEL JOHN and CAMARA, MIGUEL., 2018. Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. Journal of Medicinal Chemistry. Ahead of Print

Content: LEE, JONG BONG, ZGAIR, ATHEER, MALEC, JED, KIM, TAE HWAN, KIM, MIN GI, ALI, JOSEPH, QIN, CHAOLONG, FENG, WANSHAN, CHIANG, MANTING, GAO, XIZHE, VORONIN, GREGORY, GARCES, AIMIE E, LAU, CHUN LONG, CHAN, TING-HOI, HUME, AMY, MCINTOSH, TECASHANELL M, SOUKARIEH, FADI, AL-HAYALI, MOHAMMED, CIPOLLA, ELENA, COLLINS, HILARY M, HEERY, DAVID M, SHIN, BEOM SOO, YOO, SUN DONG, KAGAN, LEONID, STOCKS, MICHAEL J, BRADSHAW, TRACEY D, FISCHER, PETER M and GERSHKOVICH, PAVEL., 2018. Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system. Journal of Controlled Release. 286, 10-19

Content: GARCES, AIMIE E and STOCKS, MICHAEL J, 2018. Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective. Journal of Medicinal Chemistry. Ahead of Print

Content: MINHAS, HARSIMRAN K., RILEY, WILLIAM, STUART, ALISON M. and URBONAITE, MARTYNA, 2018. Activation of the hypervalent fluoroiodane reagent by hydrogen bonding to hexafluoroisopropanol ORGANIC & BIOMOLECULAR CHEMISTRY. 16(39), 7170-7173

Content: FYFE, TJ, ZARZYCKA, B, LIM, HD, KELLAM, B, MISTRY, SN, KATRICH, V, SCAMMELLS, PJ, LANE, JR and CAPUANO, B, 2018. A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor Journal of Medicinal Chemistry. 62(1), 174-206

Content: VAN DER WESTHUIZEN, ET, SPATHIS, A, KHAJEHALI, E, JORG, M, MISTRY, SN, CAPUANO, B, TOBIN, AB, SEXTON, PM, SCAMMELLS, PJ, VALANT, C and CHRISTOPOULOS, A, 2018. Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptor Molecular Pharmacology. (In Press.)

Content: ALCOBIA, DIANA C., ZIEGLER, ALEXANDRA, I, KONDRASHOV, ALEXANDER, COMEO, ELEONORA, MISTRY, SARAH, KELLAM, BARRIE, CHANG, AESON, WOOLARD, JEANETTE, HILL, STEPHEN J. and SLOAN, ERICA K., 2018. Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET ISCIENCE. 6, 280-+

Publications