Neele Dellschaft

Contact

• workRoom 23 SPMIC
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 84 67774
• Neele.Dellschaft@nottingham.ac.uk

Biography

I attended the Technical University in Munich for a B.Sc. in Human Nutrition followed by an M.Sc. in Molecular Nutrition in the Netherlands at Wageningen University. For my Ph.D. I undertook two projects, one at the University of Nottingham and the second at the University of Alberta in Canada in which I studied the influence of perinatal nutrition on the longterm health of the offspring, focusing on metabolic health and appetite regulation. My first post-doctoral project continued my research in this field in the French Institute for Agronomical Research, INRA, in Nantes. Since 2015 I have been back in Nottingham, working as a research fellow, first in Child Health, Obstetrics and Gynaecology, and since 2017 at the Sir Peter Mansfield Imaging Centre.

Research Summary

I am working at the Sir Peter Mansfield Imaging Centre on a number of projects including digestive health (in people with cystic fibrosis; in constipation; in the rare chronic intestinal… read more

Selected Publications

• DELLSCHAFT NS, ALEXANDRE-GOUABAU M, GARDNER DS, ANTIGNAC J, KEISLER DH, BUDGE H, SYMONDS ME and SEBERT SP, 2015. Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring. The Journal of endocrinology. 224(2), 171-82
• SEBERT, S.P., DELLSCHAFT, N.S., CHAN, L.L.Y., STREET, H., HENRY, M., FRANCOIS, C., SHARMA, V., FAINBERG, H.P., PATEL, N., RODA, J., KEISLER, D., BUDGE, H. and SYMONDS, M.E., 2011. Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa Endocrinology. 152(7), 2816-2826
• CAUDILL MA, DELLSCHAFT N, SOLIS C, HINKIS S, IVANOV AA, NASH-BARBOZA S, RANDALL KE, JACKSON B, SOLOMITA GN and VERMEYLEN F, 2009. Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype. The Journal of nutrition. 139(4), 727-33
• BOUWENS M, VAN DE REST O, DELLSCHAFT N, BROMHAAR MG, DE GROOT LCPGM, GELEIJNSE JM, MÜLLER M and AFMAN LA, 2009. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. The American journal of clinical nutrition. 90(2), 415-24

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Current Research

I am working at the Sir Peter Mansfield Imaging Centre on a number of projects including digestive health (in people with cystic fibrosis; in constipation; in the rare chronic intestinal pseudo-obstruction; assessment of pancreatic health) and investigating placental physiology in healthy and compromised pregnancies. These projects allow me to apply my knowledge in physiology (perinatal health, longterm metabolic health, nutrition) using a new tool: MRI permits drawing conclusions on function as well as anatomy of the organs we investigate.

Past Research

In the past I worked on projects on the effect that maternal obesity and diabetes have on the offspring in the long term. These offspring are more likely to develop obesity and diabetes themselves and this is, in part, due to the high-nutrient environment that the fetus is exposed to during the pregnancy, having direct effects on their development. I especially investigated the role of brown fat, a heat-producing tissue which may have a role in preventing the development of obesity.

• DELLSCHAFT, NEELE S, NG, CHRISTABELLA, HOAD, CAROLINE, MARCIANI, LUCA, SPILLER, ROBIN, STEWART, IAIN, MENYS, ALEX, BARR, HELEN, GOWLAND, PENNY A, MAJOR, GILES and SMYTH, ALAN R, 2022. Magnetic resonance imaging of the gastrointestinal tract shows reduced small bowel motility and altered chyme in cystic fibrosis compared to controls. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 21(3), 502-505
• DELLSCHAFT, NEELE, HOAD, CAROLINE, MARCIANI, LUCA, GOWLAND, PENNY and SPILLER, ROBIN, 2022. Small bowel water content assessed by MRI in health and disease: a collation of single-centre studies ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 55(3), 327-338
• NG, C., DELLSCHAFT, N. S., HOAD, C. L., MARCIANI, L., BAN, L., PRAYLE, A. P., BARR, H. L., JAUDSZUS, A., MAINZ, J. G., SPILLER, R. C., GOWLAND, P., MAJOR, G. and SMYTH, A. R., 2020. Postprandial changes in gastrointestinal function and transit in cystic fibrosis assessed by Magnetic Resonance Imaging: J Cyst Fibros J Cyst Fibros.
• DELLSCHAFT, N. S., HUTCHINSON, G., SHAH, S., JONES, N. W., BRADLEY, C., LEACH, L., PLATT, C., BOWTELL, R. and GOWLAND, P. A., 2020. The haemodynamics of the human placenta in utero PLoS Biol. 18(5), e3000676
• ALBUSTANJI L, PEREZ GS, ALHARETHI E, ALDISS P, BLOOR I, BARRETO-MEDEIROS JM, BUDGE H, SYMONDS ME and DELLSCHAFT N, 2019. Housing Temperature Modulates the Impact of Diet-Induced Rise in Fat Mass on Adipose Tissue Before and During Pregnancy in Rats. Frontiers in physiology. 10, 209
• WILKINSON-SMITH V, DELLSCHAFT N, ANSELL J, HOAD C, MARCIANI L, GOWLAND P and SPILLER R, 2019. Mechanisms underlying effects of kiwifruit on intestinal function shown by MRI in healthy volunteers. Alimentary pharmacology & therapeutics. 49(6), 759-768
• SYMONDS ME, ALDISS P, DELLSCHAFT N, LAW J, FAINBERG HP, POPE M, SACKS H and BUDGE H, 2018. Brown adipose tissue development and function and its impact on reproduction. The Journal of endocrinology. 238(1), R53-R62
• SAROHA V, DELLSCHAFT NS, KEISLER DH, GARDNER DS, BUDGE H, SEBERT SP and SYMONDS ME, 2017. Tissue cell stress response to obesity and its interaction with late gestation diet. Reproduction, fertility, and development. (In Press.)
• ALDISS, P., DELLSCHAFT, N., SACKS, H., BUDGE, H. and SYMONDS, M.E., 2017. Beyond obesity - thermogenic adipocytes and cardiometabolic health Hormone Molecular Biology and Clinical Investigation. 31(2),
• DELLSCHAFT NS, RICHARD C, LEWIS ED, GORUK S, JACOBS RL, CURTIS JM and FIELD CJ, 2017. The dietary form of choline during lactation affects maternal immune function in rats. European journal of nutrition. 57(6), 2189-2199
• ALDISS P, DELLSCHAFT N, SACKS H, BUDGE H and SYMONDS ME, 2017. Beyond obesity - thermogenic adipocytes and cardiometabolic health. Hormone molecular biology and clinical investigation. 31(2),
• LEWIS ED, RICHARD C, GORUK S, DELLSCHAFT NS, CURTIS JM, JACOBS RL and FIELD CJ, 2016. The Form of Choline in the Maternal Diet Affects Immune Development in Suckled Rat Offspring. The Journal of nutrition. 146(4), 823-30
• SYMONDS ME, DELLSCHAFT N, POPE M, BIRTWISTLE M, ALAGAL R, KEISLER D and BUDGE H, 2016. Developmental programming, adiposity, and reproduction in ruminants. Theriogenology. 86(1), 120-9
• LEWIS ED, GORUK S, RICHARD C, DELLSCHAFT NS, CURTIS JM, JACOBS RL and FIELD CJ, 2016. Feeding a diet devoid of choline to lactating rodents restricts growth and lymphocyte development in offspring. The British journal of nutrition. 116(6), 1001-12
• DELLSCHAFT NS, ALEXANDRE-GOUABAU M, GARDNER DS, ANTIGNAC J, KEISLER DH, BUDGE H, SYMONDS ME and SEBERT SP, 2015. Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring. The Journal of endocrinology. 224(2), 171-82
• DELLSCHAFT NS, RUTH MR, GORUK S, LEWIS ED, RICHARD C, JACOBS RL, CURTIS JM and FIELD CJ, 2015. Choline is required in the diet of lactating dams to maintain maternal immune function. The British journal of nutrition. 113(11), 1723-31
• SEBERT, S.P., DELLSCHAFT, N.S., CHAN, L.L.Y., STREET, H., HENRY, M., FRANCOIS, C., SHARMA, V., FAINBERG, H.P., PATEL, N., RODA, J., KEISLER, D., BUDGE, H. and SYMONDS, M.E., 2011. Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa Endocrinology. 152(7), 2816-2826
• CAUDILL MA, DELLSCHAFT N, SOLIS C, HINKIS S, IVANOV AA, NASH-BARBOZA S, RANDALL KE, JACKSON B, SOLOMITA GN and VERMEYLEN F, 2009. Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype. The Journal of nutrition. 139(4), 727-33
• BOUWENS M, VAN DE REST O, DELLSCHAFT N, BROMHAAR MG, DE GROOT LCPGM, GELEIJNSE JM, MÜLLER M and AFMAN LA, 2009. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. The American journal of clinical nutrition. 90(2), 415-24