Publications
36. “Cathodic Radical Cyclisation of Aryl Halides Using a Strongly-Reducing Catalytic Mediator in Flow”, A. A. Folgueiras-Amador, A. E. Teuten, M. Salam-Perez, J. E. Pearce, G. Denuault, D. Pletcher, P. J. Parsons, D. C. Harrowven, R. C. D. Brown, Angewandte Chemie International Edition. August 2022, 61, 35, https://doi.org/10.1002/anie.202203694
35. "Wavelength Dependent Photoextrusion and Tandem Photoextrusion Reactions of Ninhydrin bis-Acetals for the Synthesis of 8-Ring Lactones, Benzocyclobutenes and Orthoanhydrides" , D. C. Harrowven, W. Sun, S. Kayal, W. A. T. Raimbach, X.Z. Sun, M.E. Light, M.W.D. Heine and M.W. George, Chem. Commun, 2022 doi.org/10.1039/D1CC06800H
34. "New approaches to ondansetron and alosetron inspire a versatile, flow photochemical method for indole synthesis" W. Sun, W. A. T. Raimbach, L. D. Elliott, K. I. Booker-Milburn and D. C. Harrowven, Chem. Commun, 2022, 58, 383-386, doi.org/10.1039/D1CC05700F
33. "Self-Optimization of Continuous Flow Electrochemical Synthesis Using Fourier Transform Infrared and Gas Chromatography", J. Ke, C. Gao, A.A. Folgueiras-Amador, K.E. Jolley, O. De Frutos, C. Mateos, J.A. Rincon, R.C.D. Brown, M. Poliakoff, M.W. George, Applied Spectroscopy. December 2021, doi:10.1177/00037028211059848
32. "Integrated Multistep Photochemical and Thermal Continuous Flow Reactions: Production of Bicyclic Lactones with Kilogram Productivity" , R.A.Howie, L.D.Elliott, S.Kayal, X.Z. Sun, M.W.D. Hanson-Heine, J. Hunter, C.A.Clarke, A.Love, C.Wiseall, D.S. Lee, M.Poliakoff, K.I. Booker-Milburn and M.W.George, Org. Process Res.Dev. 2021, 25, 9, 2052–2059, https://doi.org/10.1021/acs.oprd.1c00089
31. "Daisy-chaining Photo- and Thermal Chemistry: Multistep Continuous Flow Synthesis of Visible-Light-Mediated Photochemistry with a High-Temperature Cascade Reaction" L.D. Elliott, K.I. Booker-Milburn, A.J.J. Lennox, Org. Process Res.Dev. 2021, 25,8, 1943-1949, doi.org/10.1021/acs.oprd.1c00187
30. “A Continuous-Flow Electrochemical Taylor Vortex Reactor: A Laboratory-Scale High-Throughput Flow Reactor with Enhanced Mixing for Scalable Electrosynthesis” A. Love, D.S. Lee, G. Gennari, R. Jefferson-Loveday, S.J. Pickering, M .Poliakoff and M. W. George, Org. Process Res.Dev. 2021, 25, 7, 1619–1627 https://doi.org/10.1021/acs.oprd.1c00102
29. "Multi-gram Synthesis of Trioxanes Enabled by a Supercritical CO2 Integrated Flow Process” L. Wu ; B.L. Abreu, A.J. Blake, L.J.Taylor, W. Lewis, S. P. Argent, M. Poliakoff, H. Boufroura, M.W. George Org. Process Res. Dev. 2021, 25, 8, 1873–1881, doi.org/10.1021/acs.oprd.1c00111
28. " A new mode of cyclobutenedione ring opening for the synthesis of 2-oxobut-3-enamides and tetrasubstituted furans” R.M. Bennett, W.Sun, D.C. Wilson, M.E.Light and D.C. Harrowven, Chem. Commun, 2021, 57, 5694-5697, DOI: 10.1039/DICC02097H
27. " A Photochemical Ring Expansion of 6-to 8-membered nitrogen heterocycles by [1,3]-sigmatropic rearrangement" M. A. Manning, W. Sun, M.E. Light and D.C. Harrowven, Chem. Commun, 2021, 57, 4556 DOI: 10.1039/d1cc00393c
26. “Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives” B. Cox, J. Duffy, V. Zdorichenko, C. Bellanger, J. Hurcum, B.Laleu, K. I. Booker-Milburn, L.D. Elliott, M. Robertson-Ralph, C.J. Swain, S.J. Bishop, I.Hallyburton, M. Anderson, CS Med. Chem. Lett, 2020, 11, 12, 2497–2503 doi.org/10.1021/acsmedchemlett.0c00486
25. "Total synthesis of polymorphatin A, a macrocyclic bisbibenzyl with boat configured arenes," F.A. Almalki, W. Sun, M.E. Light, D.C. Harrowven, Tetrahedron, 2020, 76 (42), 131521 , DOI: 10.1016/j.tet.2020.131521.
24. "Rational Design of Triplet Sensitizers for the Transfer of Excited State Photochemistry from UV to Visible," L.D. Elliott, S. Kayal, M.W. George, and K.I. Booker-Milburn, J. Am. Chem. Soc., 2020, 142, 14947-14956, DOI: 10.1021/jacs.0c05069.
23. “Escaping from Flatland: Substituted Bridged Pyrrolidine Fragments with Inherent Three-Dimensional Character”, B. Cox, V. Zdorichenko, P.B. Cox, K.I. Booker-Milburn, R. Paumier, L.D. Elliott, M. Robertson-Ralph, and G. Bloomfield, ACS Med. Chem. Lett., 2020, 11 (6), 1185-1190, DOI: 10.1021/acsmedchemlett.0c00039.
22. "A Design of Flow Electrolysis Cell for 'Home' Fabrication", A. A. Folgueiras-Amador, A. Teuten, D. Pletcher and R.C.D. Brown, React. Chem. Eng., 2020, 5, 712-718, DOI: 10.1039/D0RE00019A.
21. "Scalable Continuous Vortex Reactor for Gram to Kilo Scale for UV and Visible Photochemistry", D. S. Lee, M. Sharabi, R. Jefferson-Loveday, S.J. Pickering, M. Poliakoff, and M. W. George, Org. Process Res. Dev., 2020, 24 (2), 201-206, DOI: 10.1021/acs.oprd.9b00475.
20. "In vitro cytotoxicity assessment of monocationic and dicationic pyridium-based ionic liquids on HeLa, MCF-7, BGM, and EA.hy926 cell lines", S. A. Perez, M. G. Montalban, G. Carissimi, P. Licence, G. Villora, J. Hazard. Mater., 2020, 385, DOI: 10.1016/j.hazmat.2019.121513.
19. “Escaping from Flatland: [2+2] Photocycloaddition; Conformationally Constrained sp3-richScaffolds for Lead
Generation”, C. Cox, K.I. Booker-Milburn, L.D. Elliott, M. Robertson-Ralph, and V. Zdorichenko, ACS Med. Chem. Lett., 2019, 10 (11), 1512-1517, DOI:10.1021/ascmedchemlett.9b00409.
18. "Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions," D.E. Collin, A.A. Folgueiras-Amador, D. Pletcher, M.E. Light, B. Linclau, R.C.D. Brown, Chem. Eur. J., 2020, 26, 374-378, DOI: 10.1002/chem.201904479.
17. "In Situ Sulfidation of Pd/C: A Straightforward Method for Chemoselective Conjugate Reduction by Continuous Hydrogenation", J. C. Moore, R. A. Howie, S. L. Bourne, G. N. Jenkins, P. Licence, M. Poliakoff, and M. W. George, ASC Sustain Chem Eng, 2019, 7 (19), 16814-16819, DOI: 10.1021/acssuschemeng.9b04347.
16. "Tuning the Reactivity of TEMPO during Electrocatalytic Alcohol Oxidations in Room-Temperature Ionic Liquids”, A. E. Delorme, V. Sans, P. Licence, D. A. Walsh, ACS Sustain Chem Eng, 2019, 7, 11691-11699, DOI: 10.1021/acssuschemeng.9b01823.
15. “On The Real Catalytically Active Species for CO2 Fixation into Cyclic Carbonates Under Near Ambient Conditions: Dissociation Equilibrium of [BMIm][Fe(NO)2Cl2] Dependant on Reaction Temperature.” M. K. Leu, I. Vicente, J. Alves Fernandes, I De Pedro, J. Dupont, V. Sans,P. Licence, A. Gual and I. Cano, Appl Catal B: Environ, 2019, 245, 240-250, DOI: 10.1016/j.apcatb.2018.12.062.
14.“Sequential Photochemical and Prins Reactions for the Diasteroselective Synthesis of Tricyclic Scaffolds,” K.I. Booker-Milburn, B. Donnelly, L. Elliott, and C. Willis, Angew. Chem. Int. Ed., 2019, 58, 9095-9098, DOI: 10.1002/anie.201903488.
13. “Photochemically Produced Aminocyclobutanes as Masked Dienes in Thermal Electrocyclic Cascade Reactions”, L.D. Elliott and K.I. Booker-Milburn, Org. Lett., 2019, 21 (5), 1463-1466, DOI: 10.1021/acs.orglett.9b00211.
12. "The influence of non-ionic surfactants on electrosynthesis in extended channel, narrow gap electrolysis cells", A. Folgueiras-Amador, K.E. Jolley, P.R. Birkin, R.C.D.B. Brown, D. Pletcher, S. Pickering, M. Sharabi, O. de Frutos, C. Mataeos, and J.A. Rincon, Electrochem. Commun., 2019, 100, 6-10, DOI:10.1016/j.elecom.2019.01.009.
11. “The Impact of Sulfur Functionalisation on Nitrogen-based Ionic Liquid Cations”, A. R. Santos,R. M. W. D. Hanson-Heine, N. A. Besley and P. Licence, Chem. Commun., 2018, 54, 11403-11406, DOI: 10.1039/c8cc05515g.
10."A Thermally Induced Hydride Transfer from an Amine to an Allene Triggers and Annulation Reaction, Giving Dihydrofuropyridinones", W. Sun, D.C. Wilson, M.E. Light, and D.C. Harrowven, Org. Lett., 2018, 20 (14), 4346-4349, DOI: 10.1021/acs.orglett.8b01792.
9. “A New Approach to Sustainability: A Moore's Law for Chemistry”, M. Poliakoff, P. Licence, M. W. George, Angew. Chem., 2018, 57, DOI: 10.1002/anie.201804004.
8. “UN Sustainable Development Goals: How Can Sustainable/Green Chemistry Contribute? By Doing Things Differently”, M. Poliakoff, P. Licence, M. W. George, Curr. Opin. Green Sustain. Chem., 2018, 13, 146-149, DOI: 10.1016/j.cogsc.2018.04.011.
7. “Photooxidation of Fulvenes in a Continuous Flow Photoreactor using Carbon Dioxide as a Solvent”, L. Wu D. S.
Lee, H. Boufroura, M. Poliakoff and M. W. George, ChemPhotoChem, 2018, 2, DOI: 10.1002/cptc.201800033.
6. “UV PhotoVap: Demonstrating How a Simple and Versatile Reactor Based on a Conventional Rotary Evaporator Can Be Used for UV Photochemistry”, C. A. Clark, D. S. Lee, S. J. Pickering, M. Poliakoff, and M. W. George, Org. Process Res. Dev., 2018, 22, 595-599, DOI: 10.1021/acs.oprd.8b00037.
5. "Using batch reactor results to calculate optimal flow rates for the scale-up of UV photochemical reactions", L.D. Elliott, J.P. Knowles, C.S. Stacey, D.J. Klauber, K.I. Booker-Milburn, React. Chem. Eng., 2018, 3, 86-93, DOI: 10.1039/C7RE00193B.
4. "Combining Engineering and Chemistry for the Selective Continuous Production of Four Different Oxygenated Compounds by Photooxidation of Cyclopentadiene using Liquid and Supercritical CO2 as Solvents", L. Wu, Z. Abada, D.S. Lee, M. Poliakoff, M.W. George, Tetrahedron, 2018, 74 (25), 3107-3112, DOI 10.1016/j.tet.2017.11.048.
3. "Flow Electrolysis Cells for the Synthetic Organic Chemistry Laboratory", D. Pletcher, R.A. Green, R.C.D. Brown, Chem. Rev. 2018, 118 (9), 4573-4591, DOI: 10.1021/acs.chemrev.7b00360.
2. "Continuous Photo-Oxidation in a Vortex Reactor: Efficient Operations Using Air Drawn from the Laboratory", D.S. Lee, Z. Amara, C.A. Clark, Z.Y. Xu, B. Kakimpa, H.P. Morvan, S.J. Pickering, M. Poliakoff, M.W. George, Org. Process Res. Dev. 2017, 21, 1042–1050, DOI: 10.1021/acs.oprd.7b00153.
1. "A Laboratory-scale Annular Continuous Flow Reactor for UV Photochemistry using Excimer Lamps for Discrete Wavelength Excitation and its use in a Wavelength Study of a Photodecarboxylative Cyclisation", E.N. Delaney, D.S. Lee, L.D. Elliott, J. Jin, K.I. Booker-Milburn, M. Poliakoff, M.W. George, Green Chem. 2017, 19, 1431–1438, DOI: 10.1039/C6GC02888H.
