Respiratory Research
 

Ian Sayers

Professor of Respiratory Molecular Genetics, Faculty of Medicine & Health Sciences

Contact

  • workRoom D207B Biodiscovery Institute, Science Road
    University Park
    Nottingham
    NG7 2RD
    UK
  • work0115 823 1066
  • fax0115 823 1059

Biography

Ian Sayers graduated with a BSc in Biochemistry from Sheffield University, UK in 1993. He stayed at Sheffield and undertook research into the molecular basis of Immunoglobulin E (IgE) receptor interactions with a focus on therapeutic intervention in allergy graduating with a PhD in 1997. Dr Sayers has maintained his research interest in the molecular basis of asthma and allergy spending time with the Asthma Genetics Group in Southampton, UK (1998-2001) and in pre-clinical drug development in New Zealand at Genesis Research and Development Corporation and the Malaghan Institute (2001-2003). In 2004, Dr Sayers joined the University of Nottingham as a Lecturer and has developed a research group focussed to understanding the cellular and molecular mechanisms underlying asthma and COPD. He has subsequently been promoted to Associate Professor (2010), Reader (2013) and Professor (2017).

Expertise Summary

  • Molecular genetics
  • Primary airway cell models
  • Large scale genetic association/linkage studies
  • Recombinant protein expression in bacteria, yeast and mammalian systems
  • Site-directed mutagenesis
  • Protein purification/analysis
  • Gene expression profiling
  • Promoter-reporter technology
  • Flow cytometry
  • RNA-seq

Teaching Summary

I co-ordinate the Respiratory Medicine short course given to medical students in their 3rd year which provides a comprehensive overview of both clinical a research topics of relevance to asthma,… read more

Research Summary

Research Interests

  • Molecular, genetic and cellular mechanisms underlying Asthma & Chronic Obstructive Pulmonary Disease.
  • Stratified medicine in respiratory disease.
  • Virus - host interactions in the airways.

Selected Publications

Division of Respiratory Medicine, The School of Medicine

The University of Nottingham
Clinical Sciences Building
Nottingham City Hospital
Hucknall Road
Nottingham, NG7 2UH


telephone: +44 (0) 115 82 31317
email:helen.naylor@nottingham.ac.uk