State of the art system capable of targeted quantitation, wide range screening, and untargeted metabolomics. Samples are separated via a suitable chromatographic method, ionised via (+) or (-) ESI, then separated on the basis of mass to charge ratio via the TOF mass analyser. A Quadrupole mass analyser allows for the isolation and subsequent fragmentation of unknowns, which can be annotated using exact mass and fragmentation patterns via Sirius software.

This system is capable of high sensitivity quantitation of non-volatile targets in a range of complex matrices. This system uses an identical UHPLC front end as our LC Q-TOF, making for easy transfer of chromatographic methods between the two systems.

This system uses full immersion in liquid nitrogen to embrittle even the hardest samples. A steel rod is propelled between electromagnets to reduce the sample to a fine powder, without incurring friction induced heat damage. Typical sample weights can range from 1-25g. Wet samples typically require freeze drying before this milling process is applied, to prevent stickiness on thawing

This unit uses ceramic bead media to homogenise samples in both wet and dry modes. Uses standard 1.5 ml micro centrifuge tubes for low frequency milling, or 2ml milling tubes for higher intensity milling.

Compatible with a wide range of solid phase extraction cartridges, this system can be used to retain target analytes whilst allowing interfering compounds to be washed to waste

This system enables the removal of organic solvents at atmospheric pressure, under a stream of nitrogen gas

This system enables the removal of solvent mixtures, under vacuum, without bumping. Compatible with well plates, as well as 1.5 and 15 ml centrifuge tubes

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