People

Hany Elsheikha

Professor of Interdisciplinary Parasitology, Faculty of Medicine & Health Sciences

Contact

workRoom B75 School of Veterinary Medicine and Science
Sutton Bonington Campus
Sutton Bonington
Leicestershire
LE12 5RD
UK
work0115 951 6445
fax0115 95 16440
hany.elsheikha@nottingham.ac.uk
http://www.nottingham.ac.uk/vet/people/hany.elsheikha

Biography

Hany Elsheikha is a Professor of Interdisciplinary Parasitology in the global health department in School of Veterinary Medicine and Science, University of Nottingham (SVMS-UoN). Hany is also a European Veterinary Parasitology College diplomate, a European Scientific Counsel Companion Animal Parasites member and a Fellow of the Higher Education Academy. He earned his PhD from Michigan State University for research performed on the molecular evolution of the causative agent of equine protozoal myeloencephalitis. He was awarded the prestigious American Society for Microbiology (ASM)/National Center for Infectious Diseases (NCID) Postdoctoral Fellowship. Since joining SVMS-UoN, he has been spearheading the development and delivery of parasitology teaching. Also, he has established a multidisciplinary research programme focused on decoding the interkingdom chemical communication between the host cells and neuropathogenic protozoan parasites, with a special interest in Toxoplasma gondii. Key areas of interest include host-parasite interaction, anti-parasitic drug discovery, parasite evolution and parasites of public health impacts. He has published more than 270 peer-reviewed papers and many other articles in professional magazines and science communication journals. Hany has published 8 books in veterinary, tropical and medical parasitology for students, residents and professionals.

Expertise Summary

I support the aims of the School of Veterinary Medicine and Science, University of Nottingham by creating a teaching and learning environment with the highest academic standards for both PG and UG students. Innovative development of this environment is on-going and includes an integrated veterinary parasitology module and a multidisciplinary research and training programme.

Teaching Summary

Research Summary

Selected Publications

ELSHEIKHA, H.M. and KHAN, N.A., 2010. Protozoa traversal of the blood-brain barrier to invade the central nervous system. FEMS Microbiology Reviews. 34(4), 532-553
ELSHEIKHA, H.M. and ZHAO, X., 2008. Patterns and role of diversifying selection in the evolution of Toxoplasma gondii SAG5 locus. Parasitology Research. 103(1), 201-207
ELSHEIKHA, H M, 2008. Congenital toxoplasmosis: priorities for further health promotion action. Public Health. 122(4), 335-53
ELSHEIKHA,, 2008. Safer food for pregnant women: Practices and risks. Public Health. 122, 1407-1409

View all publications

Innovation and forward-looking vision of where the veterinary medical education is heading is the main drive of my philosophy in teaching. My educational research focuses on technology-aided curriculum development and student assessment in active learning formats [J. Vet. Med. Educ. 2009, 36(3):291-296], and teaching students in the digital age [Med. Educ. 2013, 47(5):518-519]. I constantly develop new ways of stimulating curiosity in my students. I developed iPad and iPhone applications and use latest audio-visual (AV) and digital technologies as well as online resources to motivate students and enhance their learning experience. These resources are used to supplement didactic lectures to create more interactive/engaging atmosphere and to foster problem-based and situated learning.

I am in charge of teaching and convening the whole integrated clinical and veterinary parasitology curriculum to the Nottingham Veterinary students. I instruct graduate and veterinary students in parasitology, zoonotic diseases, public health, clinical diagnostics, and parasite pathogenesis. Also, I direct examination, teaching and tutoring of students in the Vet School.

I realized the need of vet students for a new textbook in parasitology that suits their style of learning, and this was the drive behind my enthusiasm to publish 2 textbooks, "Essentials of Veterinary Parasitology" and "Self-Assessment Colour Review Veterinary Parasitology", to help students to learn the subject in an easy and more effective manner. Comments published by peers about the books have been extremely positive (http://www.horizonpress.com/veterinary-parasitology).

Current Research

My research interests include host-pathogen interaction, anti-parasitic drug discovery and evolutionary aspects of parasitic diseases at the animal-public health interface. We use a multidisciplinary approach to investigate contemporary problems in parasite biology, pathogenesis and therapeutics. Main areas of current research activity are listed below.

1. Neuroparasitology. Primary requirements in neurological infections due to protozoan parasites include hematogenous spread, followed by parasite invasion of the central nervous system. However, it is not clear how do these organisms cross the blood-brain barrier leading to neurologic dysfunction. We investigate the mechanism by which the protozoan parasites Neospora caninum breaches this barrier by interacting with the brain microvascular endothelial cells, which constitute the blood-brain barrier.

2. Modeling and molecular biology of parasitic diseases. The aim of this research focus is to develop alternative animal models to understand host/pathogen interactions, and for the development of new diagnostics, therapeutics and vaccines for parasitic diseases. We developed an experimental invertebrate model to replace the use of rodents in elucidating the pathophysiology of toxoplasmosis and neosporiosis, a leading cause of abortion and infertility problems in farm animals. This research aims at employing therapeutic modalities to interrupt the development of these parasitic infections.

3. Plasticity of Neospora caninum and bradyzoite-tachyzopite switching. Neosporosis is a parasitic disease caused by the protozoan parasite Neospora caninum. In the last two decades, N. caninum has been widely recognized as one of the most frequently diagnosed cause of infectious abortion, stillbirth, and maternal infertility in cattle and neurological disease in various animal species. To survive in the host, N. caninum has the ability to convert to cystic form with a thick capsule both in vivo and in vitro using a poorly understood pathway, this may partly explains the difficulties in the treatment of this infection. Switching between bradyzoite and tachyzoite stages is the key step in the pathogenesis of N. caninum infection. Despite attempts to investigate this biological phenomenon, it is evidenced today that this switching process is a highly concerted multistep process requiring a variety of molecular interactions between parasite, mammalian host cells and environmental factors. Additionally, there is not enough knowledge on the biological, biochemical and biophysical properties of membrane/cyst wall of N. caninum bradyzoite stage and their structure function relationships. This project aims to obtain in depth knowledge on the mechanism and factors involved in the transformation between bradyzoite and tachyzoite stages of N. caninum.

4. Molecular pathogenesis and stress tolerance in Toxoplasma gondii. I study host-pathogen interactions that occur during the establishment of intracellular infection by T. gondii in response to stress. As the causative agent of toxoplasmosis disease in humans and animals, T. gondii represents an important public health and economic problem worldwide, where at least third of the world population are infected. While recent advances in the field have provided a new paradigm for parasite survival within the host cell, little is known regarding the molecular and cellular events required to shape a tolerant host cell environment for intracellular development and endurance of this pathogen. It is the understanding of these basic processes that will guide our efforts toward effective prevention or control of toxoplasmosis disease.

5. Educational research. My educational research focuses on developing new ways of stimulating curiosity in students.

Past Research

1. Molecular epidemiology and evolution of Sarcocytsis neurona in horses and opossums. I integrated field and molecular biology methodologies to study the epidemiology and evolutionary genetics of S. neurona, the etiologic agent of equine protozoal myeloencephalitis (EPM) in horses in the Americas. This research work was hypothesis-based. The key question was: Dose S. neurona have a clonal population structure? To answer this question, new methodologies were developed and various approaches were used to unravel the S. neurona genetic structure in natural populations. These studies included the assembly of a large collection of S. neurona strains and other cyst-forming coccidia, development of methods for purification of the sporocyst stage from intestinal cells of opossums and the merozoite stage from tissue culture and the use of DNA sequencing of the ribosomal gene and major surface antigen gene as well as sequence of the 25/396 diagnostic marker. Whole-genome fingerprinting analysis was also used to develop "species identity" or "genetic fingerprint" for S. neurona strains. These methods were applied to characterize the available Sarcocystis strains that have been assessed by preliminary phenotypic and molecular marker methods such as PCR-RFLP as "neurona-like".

2. Therapeutic efficacy of Sarcocystis neurona-specific IgG monoclonal antibodies against equine protozoal myeloencephalitis (EPM) in mice model. In this project a panel of IgG monoclonal antibodies (MAbs) was evaluated in tissue culture systems and by using Gamma-Interferon-gene-Knockout (IFN-γ-KO) mice lacking the functional gene for gamma interferon. This study revealed that the IgG response can impede the establishment of infective S. neurona parasites in the mouse and these MAbs are candidate molecules for immunotherapy of S. neurona infection in horses. The potential for use of multiple antigens as protective immunogens in preventing S. neurona infection was raised.

3. Research on besnoitiosis in donkeys and opossums. I isolated Besnoitia bennetti, which forms cysts in the connective tissues of equids (Equus asinus) for the first time from Michigan and for the second time from North America. The first-ever genetic description of Besnoitia bennetti was achieved in association with the study of an epidemic on a Michigan donkey farm. I isolated Besnoitia darlingi from opossums (Didelphis virginiana) for the first time from Michigan, developed methods for its continuous in vitro culture, developed laboratory animal model of the disease, and testing chemotherapeutic agents in cell cultures.

ELSHEIKHA, HANY M., AL-SANDAQCHI, ALAA T., HARUN, MOHAMMAD S. R., WINTERTON, FRANCESCA, ALTHARAWI, ALI, ELSAIED, NASHWA A., STEVENSON, CARL W., MACNAUGHTAN, WILLIAM, MINA, JOHN G. M., DENNY, PAUL W., CINQUE, GIANFELICE and CHAN, KA LUNG ANDREW, 2022. Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy Cells. 11, 811
LI, MAN-YAO, KANG, YUAN-HUAN, SUN, WEN-CHAO, HAO, ZHI-PENG, ELSHEIKHA, HANY M and CONG, WEI, 2022. Terrestrial runoff influences the transport and contamination levels of Toxoplasma gondii in marine organisms. The Science of the total environment. 851(Pt 1), 158168
XU, YUE, ZHENG, WEN-BIN, LI, HAO-YU, CAI, LANG, ZOU, YANG, XIE, SHI-CHEN, ZHU, XING-QUAN and ELSHEIKHA, HANY M., 2022. RNA sequencing reveals dynamic expression of spleen lncRNAs and mRNAs in Beagle dogs infected by Toxocara canis PARASITES & VECTORS. 15(1),
WANG, SHA-SHA, ZHOU, CHUN-XUE, ELSHEIKHA, HANY M, HE, JUN-JUN, ZOU, FENG-CAI, ZHENG, WEN-BIN, ZHU, XING-QUAN and ZHAO, GUANG-HUI, 2022. Additional file 9 of Temporal transcriptomic changes in long non-coding RNAs and messenger RNAs involved in the host immune and metabolic response during Toxoplasma gondii lytic cycle Figshare.
FU, YI-TIAN, YAO, CHAOQUN, DENG, YUAN-PING, ELSHEIKHA, HANY M., SHAO, RENFU, ZHU, XING-QUAN and LIU, GUO-HUA, 2022. Human pediculosis, a global public health problem INFECTIOUS DISEASES OF POVERTY. 11(1),
NIE, LAN-BI, LIANG, QIN-LI, WANG, MENG, DU, RUI, ZHANG, MENG-YUAN, ELSHEIKHA, HANY M and ZHU, XING-QUAN, 2022. Global profiling of protein lysine malonylation in Toxoplasma gondii strains of different virulence and genetic backgrounds. PLoS neglected tropical diseases. 16(5), e0010431
LI, MAN-YAO, GAO, XIAO-NAN, MA, JUN-YANG, ELSHEIKHA, HANY M. and CONG, WEI, 2022. A systematic review, meta-analysis and meta-regression of the global prevalence of Toxoplasma gondii infection in wild marine mammals and associations with epidemiological variables TRANSBOUNDARY AND EMERGING DISEASES.
LIANG, QIN-LI, NIE, LAN-BI, LI, TING-TING, ELSHEIKHA, HANY M., SUN, LI-XIU, ZHANG, ZHI-WEI, ZHAO, DAN-YU, ZHU, XING-QUAN and WANG, JIN-LEI, 2022. Functional Characterization of 17 Protein Serine/Threonine Phosphatases in Toxoplasma gondii Using CRISPR-Cas9 System FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 9,
WANG, SHA-SHA, ZHOU, CHUN-XUE, ELSHEIKHA, HANY M., HE, JUN-JUN, ZOU, FENG-CAI, ZHENG, WEN-BIN, ZHU, XING-QUAN and ZHAO, GUANG-HUI, 2022. Temporal transcriptomic changes in long non-coding RNAs and messenger RNAs involved in the host immune and metabolic response during Toxoplasma gondii lytic cycle PARASITES & VECTORS. 15(1),
MA, JUN-YANG, LI, MAN-YAO, QI, ZE-ZHENG, FU, MING, SUN, TIAN-FENG, ELSHEIKHA, HANY M. and CONG, WEI, 2022. Waterborne protozoan outbreaks: An update on the global, regional, and national prevalence from 2017 to 2020 and sources of contamination SCIENCE OF THE TOTAL ENVIRONMENT. 806,
CONG, WEI, LI, MAN-YAO, ZOU, YANG, MA, JUN-YANG, WANG, BO, JIANG, ZHAO-YANG and ELSHEIKHA, HANY M., 2021. Prevalence, genotypes and risk factors for Toxoplasma gondii contamination in marine bivalve shellfish in offshore waters in eastern China. Ecotoxicology and Environmental Safety. 213, 112048
ZHU, YU-CHAO, ELSHEIKHA, HANY M., WANG, JIAN-HUA, FANG, SHUAI, HE, JUN-JUN, ZHU, XING-QUAN and CHEN, JIA, 2021. Synergy between Toxoplasma gondii type I Delta GRA17 immunotherapy and PD-L1 checkpoint inhibition triggers the regression of targeted and distal tumors JOURNAL FOR IMMUNOTHERAPY OF CANCER. 9(11),
WANG, ZE-XIANG, HU, RUI-SI, ZHU, XING-QUAN, SUN, XIAO-LIN and ELSHEIKHA, HANY M., 2021. Global phosphoproteome analysis reveals significant differences between sporulated oocysts of virulent and avirulent strains of Toxoplasma gondii MICROBIAL PATHOGENESIS. 161,
XU, XIAO-PEI, ELSHEIKHA, HANY M., LIU, WEN-GE, ZHANG, ZHI-WEI, SUN, LI-XIU, LIANG, QIN-LI, SONG, MING-XIN and ZHU, XING-QUAN, 2021. The Role of Type II Fatty Acid Synthesis Enzymes FabZ, ODSCI, and ODSCII in the Pathogenesis of Toxoplasma gondii Infection FRONTIERS IN MICROBIOLOGY. 12,
LIU, JIE, LI, TING-TING, LIANG, QIN-LI, ELSHEIKHA, HANY M., ZHAO, DAN-YU, ZHANG, ZHI-WEI, XU, XIAO-PEI, ZHU, XING-QUAN and WANG, MENG, 2021. Characterization of functions in parasite growth and virulence of four Toxoplasma gondii genes involved in lipid synthesis by CRISPR-Cas9 system PARASITOLOGY RESEARCH. 120(11), 3749-3759
ZHENG, WEN-BIN, ZOU, YANG, LIU, QING, HU, MIN-HUA, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2021. Toxocara canis Infection Alters lncRNA and mRNA Expression Profiles of Dog Bone Marrow FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 9,
MA, JUN, HE, JUN-JUN, WANG, MENG, HOU, JUN-LING, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2021. Toxoplasma gondii induces metabolic disturbances in the hippocampus of BALB/c mice PARASITOLOGY RESEARCH. 120(8), 2805-2818
CONG, WEI and ELSHEIKHA, HANY M., 2021. Biology, Epidemiology, Clinical Features, Diagnosis, and Treatment of Selected Fish-borne Parasitic Zoonoses YALE JOURNAL OF BIOLOGY AND MEDICINE. 94(2), 297-309
EHSAN, MUHAMMAD, HU, RUI-SI, HOU, JUN-LING, ELSHEIKHA, HANY M., LI, XIAO-DONG, LIANG, PAN-HONG and ZHU, XING-QUAN, 2021. Fasciola gigantica tegumental calcium-binding EF-hand protein 4 exerts immunomodulatory effects on goat monocytes PARASITES & VECTORS. 14(1),
ZHENG, WEN-BIN, ZOU, YANG, HE, JUN-JUN, ELSHEIKHA, HANY M., LIU, GUO-HUA, HU, MIN-HUA, WANG, SHUI-LIAN and ZHU, XING-QUAN, 2021. Global profiling of lncRNAs-miRNAs-mRNAs reveals differential expression of coding genes and non-coding RNAs in the lung of beagle dogs at different stages of Toxocara canis infection INTERNATIONAL JOURNAL FOR PARASITOLOGY. 51(1), 49-61
CONG, WEI, ELSHEIKHA, HANY M., LI, MAN-YAO, MA, JUN-YANG, ZOU, YANG and JIANG, ZHAO-YANG, 2021. Molecular prevalence, risk factors and genotypes of Toxoplasma gondii DNA in wild marine snails collected from offshore waters in eastern China ACTA TROPICA. 214,
LI, FA-CAI, NIE, LAN-BI, ELSHEIKHA, HANY M., YIN, FANG-YUAN and ZHU, XING-QUAN, 2021. Lysine crotonylation is widespread on proteins of diverse functions and localizations in Toxoplasma gondii PARASITOLOGY RESEARCH. 120(5), 1617-1626
HU, RUI-SI, ZHANG, XIAO-XUAN, MA, QIAO-NI, ELSHEIKHA, HANY M., EHSAN, MUHAMMAD, ZHAO, QUAN, FROMM, BASTIAN and ZHU, XING-QUAN, 2021. Differential expression of microRNAs and tRNA fragments mediate the adaptation of the liver fluke Fasciola gigantica to its intermediate snail and definitive mammalian hosts INTERNATIONAL JOURNAL FOR PARASITOLOGY. 51(5), 405-414
WANG, SHA-SHA, CHEN, DAN, HE, JUN-JUN, ZHENG, WEN-BIN, TIAN, AI-LING, ZHAO, GUANG-HUI, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2021. Fasciola gigantica-Derived Excretory-Secretory Products Alter the Expression of mRNAs, miRNAs, lncRNAs, and circRNAs Involved in the Immune Response and Metabolism in Goat Peripheral Blood Mononuclear Cells FRONTIERS IN IMMUNOLOGY. 12,
WU, YAO-DONG, WANG, QI-QI, WANG, MENG, ELSHEIKHA, HANY M., YANG, XIN, HU, MIN, ZHU, XING-QUAN and XU, MIN-JUN, 2021. Development of a Lateral Flow Strip-Based Recombinase Polymerase Amplification Assay for the Detection of Haemonchus contortus in Goat Feces KOREAN JOURNAL OF PARASITOLOGY. 59(2), 167-171
PEREZ-COTA, FERNANDO, FUENTES-DOMINGUEZ, RAFAEL, LA CAVERA, SALVATORE, HARDIMAN, WILLIAM, YAO, MENGTING, SETCHFIELD, KERRY, MORADI, EMILIA, NAZNIN, SHAKILA, WRIGHT, AMANDA, WEBB, KEVIN F., HUETT, ALAN, FRIEL, CLAIRE, SOTTILE, VIRGINIE, ELSHEIKHA, HANY M., SMITH, RICHARD J. and CLARK, MATT, 2020. Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells JOURNAL OF APPLIED PHYSICS. 128(16),
SHI, WEI, HE, JUN-JUN, MEI, XUE-FANG, LU, KE-JING, ZENG, ZI-XUAN, ZHANG, YAO-YAO, SHENG, ZHAO-AN, ELSHEIKHA, HANY M., HUANG, WEI-YI and ZHU, XING-QUAN, 2020. Dysregulation of hepatic microRNA expression in C57BL/6 mice affected by excretory-secretory products of Fasciola gigantica PLOS NEGLECTED TROPICAL DISEASES. 14(12),
LI, JIE-XI, HE, JUN-JUN, ELSHEIKHA, HANY M., MA, JUN, XU, XIAO-PEI and ZHU, XING-QUAN, 2020. ROP18-Mediated Transcriptional Reprogramming of HEK293T Cell Reveals New Roles of ROP18 in the Interplay Between Toxoplasma gondii and the Host Cell FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 10,
LIU, GUO-HUA, SUN, MIAO-MIAO, ELSHEIKHA, HANY M., FU, YI-TIAN, SUGIYAMA, HIROMU, ANDO, KATSUHIKO, SOHN, WOON-MOK, ZHU, XING-QUAN and YAO, CHAOQUN, 2020. Human gnathostomiasis: a neglected food-borne zoonosis PARASITES & VECTORS. 13(1),
ZOU, YANG, ZHENG, WEN-BIN, HE, JUN-JUN, ELSHEIKHA, HANY M., ZHU, XING-QUAN and LU, YI-XIN, 2020. Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection FRONTIERS IN VETERINARY SCIENCE. 7,
HU, RUI-SI, ZHANG, FU-KAI, ELSHEIKHA, HANY M., MA, QIAO-NI, EHSAN, MUHAMMAD, ZHAO, QUAN and ZHU, XING-QUAN, 2020. Proteomic Profiling of the Liver, Hepatic Lymph Nodes, and Spleen of Buffaloes Infected with Fasciola gigantica PATHOGENS. 9(12),
ELSHEIKHA, HANY M., MARRA, CHRISTINA M. and ZHU, XING-QUAN, 2020. Epidemiology, Pathophysiology, Diagnosis, and Management of Cerebral Toxoplasmosis CLINICAL MICROBIOLOGY REVIEWS. 34(1),
HU, RUI-SI, HE, JUN-JUN, ELSHEIKHA, HANY M., ZOU, YANG, EHSAN, MUHAMMAD, MA, QIAO-NI, ZHU, XING-QUAN and CONG, WEI, 2020. Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts FRONTIERS IN MICROBIOLOGY. 11,
NIE, LAN-BI, LIANG, QIN-LI, ELSHEIKHA, HANY M., DU, RUI, ZHU, XING-QUAN and LI, FA-CAI, 2020. Global profiling of lysine 2-hydroxyisobutyrylome inToxoplasma gondiiusing affinity purification mass spectrometry PARASITOLOGY RESEARCH. 119(12), 4061-4071
DICKSON, AMELIYA, COOPER, ELISE, FAKAE, LENU B., WANG, BO, CHAN, KA LUNG ANDREW and ELSHEIKHA, HANY M., 2020. In Vitro Growth- and Encystation-Inhibitory Efficacies of Matcha Green Tea and Epigallocatechin Gallate Against Acanthameoba Castellanii PATHOGENS. 9(9),
TIAN, AI-LING, TIAN, XIAOWEI, CHEN, DAN, LU, MINGMIN, CALDERON-MANTILLA, GUILLERMO, YUAN, XIAO-DAN, LI, XIANGRUI, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2020. Modulation of the Functions of Goat Peripheral Blood Mononuclear Cells by Fasciola gigantica Thioredoxin Peroxidase In Vitro PATHOGENS. 9(9),
MENG, YU-MENG, ZHAI, BIN-TAO, ELSHEIKHA, HANY M., XIE, SHI-CHEN, WANG, ZE-XIANG, ZHAO, QUAN, ZHU, XING-QUAN and HE, JUN-JUN, 2020. Acetylome analysis of the feline small intestine followingToxoplasma gondiiinfection PARASITOLOGY RESEARCH. 119(11), 3649-3657
HELAL, MOHAMED A., ABDEL-GAWAD, AHMED M., KANDIL, OMNIA M., KHALIFA, MARWA M. E., CAVE, GARETH W. V., MORRISON, ALISON A., BARTLEY, DAVID J. and ELSHEIKHA, HANY M., 2020. Nematocidal Effects of a Coriander Essential Oil and Five Pure Principles on the Infective Larvae of Major Ovine Gastrointestinal Nematodes In Vitro PATHOGENS. 9(9),
ELSHEIKHA, HANY M., ALKURASHI, MAMDOWH, PALFREMAN, SUZY, CASTELLANOS, MARCOS, KONG, KENNY, NING, EVITA, ELSAIED, NASHWA A., GERAKI, KALOTINA and MACNAUGHTAN, WILLIAM, 2020. Impact of Neospora caninum Infection on the Bioenergetics and Transcriptome of Cerebrovascular Endothelial Cells PATHOGENS. 9(9),
HARUN, M. S. R., MARSH, VICTORIA, ELSAIED, NASHWA A., WEBB, KEVIN F. and ELSHEIKHA, HANY M., 2020. Effects of Toxoplasma gondii infection on the function and integrity of human cerebrovascular endothelial cells and the influence of verapamil treatment in vitro BRAIN RESEARCH. 1746,
MA, JUN, HE, JUN-JUN, HOU, JUN-LING, ZHOU, CHUN-XUE, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2020. Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry-Based Metabolomics Reveals Metabolic Alterations in the Mouse Cerebellum DuringToxoplasma gondiiInfection FRONTIERS IN MICROBIOLOGY. 11,
LI, TING-TING, WANG, JIN-LEI, LIANG, QIN-LI, SUN, LI-XIU, ZHANG, HAI-SHENG, ZHANG, ZHI-WEI, ZHU, XING-QUAN and ELSHEIKHA, HANY M., 2020. Effect of deletion of gra17 and gra23 genes on the growth, virulence, and immunogenicity of type II Toxoplasma gondii PARASITOLOGY RESEARCH. 119(9), 2907-2916
LI, ZHONG-YUAN, GUO, HAI-TING, CALDERON-MANTILLA, GUILLERMO, HE, JUN-JUN, WANG, JIN-LEI, BONEV, BOYAN B., ZHU, XING-QUAN and ELSHEIKHA, HANY M., 2020. Immunostimulatory efficacy and protective potential of putative TgERK7 protein in mice experimentally infected by Toxoplasma gondii INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. 310(5),
HARUN, MOHAMMAD S. R., TAYLOR, MICA, ZHU, XING-QUAN and ELSHEIKHA, HANY M., 2020. Transcriptome Profiling ofToxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin MICROORGANISMS. 8(6),
ELSHEIKHA, HANY M., SCHARES, GEREON, PARASCHOU, GEORGIOS, SULLIVAN, REBEKAH and FOX, RICHARD, 2020. First record of besnoitiosis caused by Besnoitia bennetti in donkeys from the UK PARASITES & VECTORS. 13(1),
ELSHEIKHA, HANY M., SIDDIQUI, RUQAIYYAH and KHAN, NAVEED AHMED, 2020. Drug Discovery against Acanthamoeba Infections: Present Knowledge and Unmet Needs PATHOGENS. 9(5),
NIE, LAN-BI, LIANG, QIN-LI, DU, RUI, ELSHEIKHA, HANY M., HAN, NAI-JIAN, LI, FA-CAI and ZHU, XING-QUAN, 2020. Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii FRONTIERS IN MICROBIOLOGY. 11,
HE, JUN-JUN, MA, JUN, WANG, JIN-LEI, ZHANG, FU-KAI, LI, JIE-XI, ZHAI, BIN-TAO, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2020. iTRAQ-based Quantitative Proteomics Analysis Identifies Host Pathways Modulated during Toxoplasma gondii Infection in Swine MICROORGANISMS. 8(4),
WU, JIANGLI, ELSHEIKHA, HANY M., TU, YANGYANG, GETACHEW, AWRARIS, ZHOU, HUAIYU, ZHOU, CHUNXUE and XU, SHUFA, 2020. Significant transcriptional changes in mature daughterVarroa destructormites during infestation of different developmental stages of honeybees PEST MANAGEMENT SCIENCE. 76(8), 2736-2743
WANG, JIN-LEI, LIANG, QIN-LI, LI, TING-TING, HE, JUN-JUN, BAI, MENG-JIE, CAO, XUE-ZHEN, ELSHEIKHA, HANY M. and ZHU, XING-QUAN, 2020. Toxoplasma gondii tkl1 Deletion Mutant Is a Promising Vaccine against Acute, Chronic, and Congenital Toxoplasmosis in Mice JOURNAL OF IMMUNOLOGY. 204(6), 1562-1570
LIANG, QIN-LI, SUN, LI-XIU, ELSHEIKHA, HANY M., CAO, XUE-ZHEN, NIE, LAN-BI, LI, TING-TING, LI, TAO-SHAN, ZHU, XING-QUAN and WANG, JIN-LEI, 2020. RH Delta gra17 Delta npt1 Strain of Toxoplasma gondii Elicits Protective Immunity Against Acute, Chronic and Congenital Toxoplasmosis in Mice MICROORGANISMS. 8(3),
ZHAI, BINTAO, HE, JUN-JUN, ELSHEIKHA, HANY M., LI, JIE-XI, ZHU, XING-QUAN and YANG, XIAOYE, 2020. Transcriptional changes in Toxoplasma gondii in response to treatment with monensin PARASITES & VECTORS. 13(1),
AZIZ, NIDA, BUTT, ABIDA and ELSHEIKHA, HANY M., 2020. Assessment of bioaccumulation of cu and Pb in experimentally exposed spiders, Lycosa terrestris and Pardosa birmanica, using different exposure routes ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH. 27(3), 3309-3319
WANG, JIN-LEI, BAI, MENG-JIE, ELSHEIKHA, HANY M., LIANG, QIN-LI, LI, TING-TING, CAO, XUE-ZHEN and ZHU, XING-QUAN, 2020. Novel roles of dense granule protein 12 (GRA12) in Toxoplasma gondii infection FASEB JOURNAL. 34(2), 3165-3178
AZIZ, NIDA, BUTT, ABIDA and ELSHEIKHA, HANY M., 2020. Antioxidant enzymes as biomarkers of Cu and Pb exposure in the ground spiders Lycosa terrestris and Pardosa birmanica ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. 190,
CONG, WEI, ZHANG, NIAN-ZHANG, HU, RUI-SI, ZOU, FENG-CAI, ZOU, YANG, ZHONG, WEN-YAN, WU, JING-JING, FALLAIZE, CHRISTOPHER J., ZHU, XING-QUAN and ELSHEIKHA, HANY M., 2020. Prevalence, risk factors and genotype distribution of Toxoplasma gondii DNA in soil in China ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY. 189,
SINJAB, FARIS, ELSHEIKHA, HANY M., DOOLEY, MAX and NOTINGHER, IOAN, 2020. Induction and measurement of the early stage of a host-parasite interaction using a combined optical trapping and Raman microspectroscopy system JOURNAL OF BIOPHOTONICS. 13(2),
CHEN XQ, ZHOU CX, ELSHEIKHA HM, HE S, HU GX and ZHU XQ, 2017. Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis. Parasites & vectors. 10(1), 339
WANG JL, ELSHEIKHA HM, ZHU WN, CHEN K, LI TT, YUE DM, ZHANG XX, HUANG SY and ZHU XQ, 2017. Immunization with Toxoplasma gondii GRA17 Deletion Mutant Induces Partial Protection and Survival in Challenged Mice. Frontiers in immunology. 8, 730
TIAN AL, LI GX, ELSHEIKHA HM, GARDNER DS, ZHANG XY, DONG W, YANG XP, LUO YY, LI HL, CONG W and ZHU XQ, 2017. Seroepidemiology of Toxoplasma gondii infection in patients with liver disease in eastern China. Epidemiology and infection. 145(11), 2296-2302
WANG ZX, ZHOU CX, ELSHEIKHA HM, HE S, ZHOU DH and ZHU XQ, 2017. Proteomic Differences between Developmental Stages of Toxoplasma gondii Revealed by iTRAQ-Based Quantitative Proteomics. Frontiers in microbiology. 8, 985
CONG W, ZHANG XX, HE JJ, LI FC, ELSHEIKHA HM and ZHU XQ, 2017. Global miRNA expression profiling of domestic cat livers following acute Toxoplasma gondii infection. Oncotarget. 8(15), 25599-25611
BAI MJ, ZOU Y, ELSHEIKHA HM, MA JG, ZHENG WB, ZHAO Q, ZHANG XX and ZHU XQ, 2017. Toxoplasma gondii Infection in Farmed Wild Boars (Sus scrofa) in Three Cities of Northeast China. Foodborne pathogens and disease. 14(7), 379-385
ZHANG XX, CONG W, ELSHEIKHA HM, LIU GH, MA JG, HUANG WY, ZHAO Q and ZHU XQ, 2017. De novo transcriptome sequencing and analysis of the juvenile and adult stages of Fasciola gigantica. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 51, 33-40
WANG JL, LI TT, ELSHEIKHA HM, CHEN K, ZHU WN, YUE DM, ZHU XQ and HUANG SY, 2017. Functional Characterization of Rhoptry Kinome in the Virulent Toxoplasma gondii RH Strain. Frontiers in microbiology. 8, 84
ZHANG FK, ZHANG XX, ELSHEIKHA HM, HE JJ, SHENG ZA, ZHENG WB, MA JG, HUANG WY, GUO AJ and ZHU XQ, 2017. Transcriptomic responses of water buffalo liver to infection with the digenetic fluke Fasciola gigantica. Parasites & vectors. 10(1), 56
LIU Q, LI FC, ELSHEIKHA HM, SUN MM and ZHU XQ, 2017. Identification of host proteins interacting with Toxoplasma gondii GRA15 (TgGRA15) by yeast two-hybrid system. Parasites & vectors. 10(1), 1
ZHOU, CHUN-XUE, ZHOU, DONG-HUI, ELSHEIKHA, HANY M., ZHAO, YU, SUO, XUN and ZHU, XING-QUAN, 2016. Metabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry SCIENTIFIC REPORTS. 6,
NAEMAT, ABIDA, ELSHEIKHA, HANY M., BOITOR, RADU A. and NOTINGHER, IOAN, 2016. Tracing amino acid exchange during host-pathogen interaction by combined stable-isotope time-resolved Raman spectral imaging SCIENTIFIC REPORTS. 6,
ZHOU, CHUN-XUE, ELSHEIKHA, HANY M., ZHOU, DONG-HUI, LIU, QING, ZHU, XING-QUAN and SUO, XUN, 2016. Dual Identification and Analysis of Differentially Expressed Transcripts of Porcine PK-15 Cells and Toxoplasma gondii during in vitro Infection FRONTIERS IN MICROBIOLOGY. 7,
HE, JUN-JUN, MA, JUN, ELSHEIKHA, HANY M., SONG, HUI-QUN, ZHOU, DONG-HUI and ZHU, XING-QUAN, 2016. Proteomic Profiling of Mouse Liver following Acute Toxoplasma gondii Infection PLOS ONE. 11(3),
HO J, PELZEL C, BEGITT A, MEE M, ELSHEIKHA HM, SCOTT DJ and VINKEMEIER U, 2016. STAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling Pathways. PLoS Biology. 14(10), e2000117
NAEMAT A, ELSHEIKHA HM, BOITOR RA and NOTINGHER I, 2016. Tracing amino acid exchange during host-pathogen interaction by combined stable-isotope time-resolved Raman spectral imaging. Scientific reports. 6, 20811
ORTEGA-RIVAS A, PADRÓN JM, VALLADARES B and ELSHEIKHA HM, 2016. Acanthamoeba castellanii: A new high-throughput method for drug screening in vitro. Acta tropica. 164, 95-99
HE JJ, MA J, ELSHEIKHA HM, SONG HQ, HUANG SY and ZHU XQ, 2016. Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection. Parasites & vectors. 9(1), 427
ZHOU CX, ZHU XQ, ELSHEIKHA HM, HE S, LI Q, ZHOU DH and SUO X, 2016. Global iTRAQ-based proteomic profiling of Toxoplasma gondii oocysts during sporulation. Journal of proteomics. 148, 12-9
ELSHEIKHA HM, SCHNYDER M, TRAVERSA D, DI CESARE A, WRIGHT I and LACHER DW, 2016. Updates on feline aelurostrongylosis and research priorities for the next decade. Parasites & vectors. 9(1), 389
WRIGHT I, STOKES L, MCGARRY J, MORGAN E, ELSHEIKHA H, WAAL TD, CABLE J and ABBOTT EM, 2016. Addressing vectorborne diseases. The Veterinary record. 178(18), 455-6
ELSHEIKHA HM and ZHU XQ, 2016. Toxoplasma gondii infection and schizophrenia: an inter-kingdom communication perspective. Current opinion in infectious diseases. 29(3), 311-8
ELSHEIKHA HM, BÜSSELBERG D and ZHU XQ, 2016. The known and missing links between Toxoplasma gondii and schizophrenia. Metabolic brain disease. 31(4), 749-59
NAEMAT, ABIDA, ELSHEIKHA, HANY M., AL-SANDAQCHI, ALAA, KONG, KENNY, GHITA, ADRIAN and NOTINGHER, IOAN, 2015. Analysis of interaction between the apicomplexan protozoan Toxoplasma gondii and host cells using label-free Raman spectroscopy ANALYST. 140(3), 756-764
ZHOU, CHUN-XUE, ZHOU, DONG-HUI, ELSHEIKHA, HANY M., LIU, GUANG-XUE, SUO, XUN and ZHU, XING-QUAN, 2015. Global Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii PLOS ONE. 10(10),
LAWSON, EDWINA, BURDEN, FAITH and ELSHEIKHA, HANY M., 2015. Pyrantel resistance in two herds of donkey in the UK VETERINARY PARASITOLOGY. 207(3-4), 346-349
ELSHEIKHA, H.M., MCKINLEY C, ELSAIED, N.A. and SMITH, P.A., 2013. Effects of Neospora caninum infection on brain microvascular endothelial cells bioenergetics Parasites & Vectors. 6(January), 24
ELSHEIKHA, HM, 2013. Pet travel Scheme update and future needs to minimise risk of exotic infection in the UK. Animal Health Advisor. 2(6), 19-22.
ORTEGA-RIVAS A, SAORÍN JL, DE LA TORRE J and ELSHEIKHA H, 2013. Touch-pad mobile devices for blended learning in immunology practicals. Medical education. 47(5), 518-9
FOSTER N and ELSHEIKHA HM, 2012. The Immune Response To Parasitic Helminths Of Veterinary Importance And Its Potential Manipulation For Future Vaccine Control Strategies. Parasitology Research: 110(5):1587-99. 110(5), 1587-1599
ZHAO G, LI J, BLAIR D, LI X, ELSHEIKHA HM, LIN R, ZOU F and ZHU X, 2012. Biotechnological Advances In The Diagnosis, Species Differentiation And Phylogenetic Analysis Of Schistosoma Spp. Biotechnology Advances. (In Press.)
ELSHEIKHA HM, 2012. Parasitic control: Fleas and worms in companion animals. Veterinary Times. 42(13), 26-30
DRINKALL E and ELSHEIKHA HM, 2012. Prevalence of Ligula intestinalis in roach: an investigative case study. Animal Health Advisor. 1(1), 22-23.
KONG K, ROWLANDS CJ, ELSHEIKHA H and NOTINGHER I, 2012. Label-free molecular analysis of live neospora caninum tachyzoites in host cells by selective scanning raman micro-spectroscopy. Analyst. 137(18), 4119-4122.
ELSHEIKHA HM, 2012. Toxoplasma gondii and heart disease. Veterinary Times. 42(39), 12-14
LAMB J, HALLOWELL GD, HARRIS P, ZHU XQ, ELSHEIKHA HM, 2012. Lipidomic Analysis of Serum from Horses with Strongyle Infection J Vet Sci Technol. 3, 122
ELSHEIKHA H, FISHER M and MCGARRY J, 2012. Protecting travelling pets from disease. The Veterinary record. 171(2), 37-8
BUTTLE, D.J., BEHNKE, J.M., BARTLEY, Y., ELSHEIKHA, H.M., BARTLEY, D.J., GARNETT, M.C., DONNAN, A.A., JACKSON, F., LOWE, A. and DUCE, I.R., 2011. Oral dosing with papaya latex is an effective anthelmintic treatment for sheep infected with Haemonchus contortus Parasites and Vectors. 4(15 March 2011), 36
SIDDIQUI, RUQAIYYAH, EMES, RICHARD, ELSHEIKHA, HANY and KHAN, NAVEED AHMED, 2011. Area 51: How do Acanthamoeba invade the central nervous system? Trends in parasitology. 27(5), 185-189
ELSHEIKHA, H.M. and SMITH, P., 2011. In vitro respiratory response of K562 cells on Neospora caninum infection In: Society for General Microbiology.
ELSHEIKHA, H.M. and KHAN, N.A, 2011. Essential of Veterinary Parasitology. First Edition, Caister Academic Press, Norfolk, United Kingdom.
ELSHEIKHA, H.M., 2011. Employing integrated approach to lungworm control in cattle. Veterinary Times. 41(4), 6-7
ELSHEIKHA, H.M., 2011. Controlling worms in small animals. Veterinary Times. 41(12), 16-18
ELSHEIKHA, H.M. and PATTERSON, J., eds., 2011. Self-Assessment Colour Review in Veterinary Parasitology Manson publication. In progress.. (In Press.)
ELSHEIKHA, H.M. and SANDS, P., 2011. Psoroptes cuniculi otitis in rabbits. Veterinary Times. 41(17), 20-22.
REGAN, C.S., YON, L. and ELSHEIKHA, H.M., 2011. Investigating the prevalence of Entamoeba species in primate populations. In: British Society for Parasitology.
MCKINLEY, C., ELSAIED, N. and ELSHEIKHA, H.M., 2011. Cultured human brain microvasular endothelial cell response upon infection with Neospora caninum In: British Society for Parasitology.
ELSHEIKHA, H.M., 2011. Controlling worm infection in companion animals. Veterinary Times. 41(9), 24-26
ALKURASHI, M., EASTICK, F.A., KUCHIPUDI, S.V., RAUCH, C., MADOUASSE, A., ZHU, X.Q. and ELSHEIKHA, H.M., 2011. Influence of culture medium pH on internalization, growth and phenotypic plasticity of Neospora caninum Veterinary Parasitology. 177(3-4), 267-274
ELSHEIKHA H, BROWN P and MIDDLETON B, 2011. Soft Thoracic Subcutaneous Mass In A Rabbit (Oryctolagus Cuniculus). Lab Animal. 40(10), 300-1
ABBOTT EM, ARTHUR J, ELSHEIKHA H, FISHER MA, JUDSON A, MCGARRY JW and MORGAN ER, 2011. Removal Of Tick Controls For Animals Entering The Uk. The Veterinary Record. 169(15), 394
AI L, CHEN M, ALASAAD S, ELSHEIKHA HM, LI J, LI H, LIN R, ZOU F, ZHU X and CHEN J, 2011. Genetic Characterization, Species Differentiation And Detection Of Fasciola Spp. By Molecular Approaches. Parasites & Vectors. 4, 101
AI, L., WENG, Y.B., ELSHEIKHA, H.M., ZHAO, G.H., ALASAAD, S., CHEN, J.X., LI, J., LI, H.L., WANG, C.R., CHEN, M.X., LIN, R.Q. and ZHU XQ, 2011. Genetic diversity and relatedness of Fasciola spp. isolates from different hosts and geographic regions revealed by analysis of mitochondrial DNA sequences Veterinary Parasitology. 181(2-4), 329-334
ELSHEIKHA, HM and KHAN, NA, eds., 2011. Essentials Of Veterinary Parasitology Wymondham : Caister Academic Press.
FEATHER, L, GOUGH, K and FLYNN, R.J. AND ELSHEIKHA, H., 2010. A retrospective investigation into risk factors of sarcoptic mange in dogs. Parasitology Research. 107, 279-283
FLYNN, R.J, ELSHEIKHA, H.M and MULCAHY, J., 2010. Coordinating innate and adaptive immunity in Fasciola hepatica infection: Implications for control. Veterinary Parasitology. 169, 235-240
FREEMAN, E., SANDS, P., FLYNN, R. and AURELIAN M, ELSHEIKHA, H.M., 2010. A retrospective study of risk factors predisposing dogs to demodicosis, and the outcome of miticidal treatment Veterinary Times. (In Press.)
SIDDIQUI, R., ELSHEIKHA, H.M. and KHAN, N.A., 2010. Enemy within: strategies to kill 'superbugs' in hospitals. International journal of antimicrobial agents. 36(3), 291
EASTICK, F.A. and ELSHEIKHA, H.M., 2010. Stress-driven stage transformation of Neospora caninum Parasitology Research. 106(5), 1009-1014
ELSHEIKHA, H., PATEL, J. and OBANDA, V, 2010. Altered helminth fauna in African elephants in response to resource availability Veterinary Times. 40(41), 26-29
SALEM, L.M.A., , Y.F. METAWEA, Y.F. and ELSHEIKHA, H.M., 2010. Prevalence of heterophyiosis in Tilapia fish and humans in Northern Egypt Parasitology Research. 107(4), 1029-1034
ELSHEIKHA, H.M. and OBANDA, V., 2010. Parasitic impact on elephant conservation: A Kenyan view. Veterinary Times. 40(19), 18-21
ELSHEIKHA, H.M. and KHAN, N.A., 2010. Protozoa traversal of the blood-brain barrier to invade the central nervous system. FEMS Microbiology Reviews. 34(4), 532-553
FISHER, M. and ELSHEIKHA, H.M., 2010. Small animal worming: Current practices and future needs Veterinary Times. 40(13), 16-17
AI, L., LI, C., ELSHEIKHA, H.M, HONG, S.J., CHEN, J.X., CHEN, S.H., LI, X., CAI, X.Q.., CHEN, J.X. and ZU, X.Q., 2010. Rapid identification and differentiation of Fasciola hepatica and Fasciola gigantica by a loop-mediated isothermal amplification (LAMP) assay Veterinary Parasitology. 174(3-4), 228-233.
AI L, DONG SJ, ZHANG WY, ELSHEIKHA HM, MAHMMOD YS, LIN RQ, YUAN ZG, SHI YL, HUANG WY and ZHU XQ, 2010. Specific Pcr-Based Assays For The Identification Of Fasciola Species: Their Development, Evaluation And Potential Usefulness In Prevalence Surveys. Annals Of Tropical Medicine And Parasitology. 104(1), 65-72
ELSHEIKHA, H.M., CLAYTON, S.J., MORSY, T.A. and YON, L.K., 2009. Parasitic zoonoses at the rodent-captive primate-human health interface Journal of the Egyptian Society of Parasitology. 39(2), 447-460
ELSHEIKHA, H.M., BROWN, P. and SKUSE, H.N.D., 2009. Death and Diarrhoea in Guinea pigs (Cavia porcellus) Lab Animal. 38(6), 189
ELSHEIKHA, H.M., ELSAIED, N. and EL-DAHTORY, F., 2009. Research Points to Staff Risks Veterinary Times. 39(17), 36-37.
ELSHEIKHA, H.M. and MORSY, T.A., 2009. Role of immune response in Toxoplasma gondii tachyzoite-bradyzoite stage interconversion: A Janus in determining disease outcome. Journal of Egyptian Society of Parasitology. 39(2), 595-598.
ELSHEIKHA, H.M., 2009. Clinical and subclinical coccidiosis: performance impacts and diagnosis Veterinary Times. 39(02), 8-10
ELSHEIKHA, H.M., 2009. Control of Persistent Ovine parasites Veterinary Times. 39(45), 20-22
ABDELMONEM, A.A., METWALLY, M.M., HUSSEIN, H.S. and ELSHEIKHA, H.M., 2009. Gross and microscopic pathological changes associated with parasitic infection in European Eel (Anguilla anguilla, Linnaeus 1758) Parasitology Research. 106(2), 463-469
ELSHEIKHA, H.M., EL-MOTAYAM, M.H., ABOUEL-NOUR, M.F. and MORSY, A.T., 2009. Oxidative stress and immune-suppression in Toxoplasma gondii positive blood donors: implications for safe blood transfusion. Journal of Egyptian Society of Parasitology. 39(2), 421-428
BOULD, J.G., ELSHEIKHA, H.M. and TOSSON, M.A., 2009. AVIAN COCCIDIOSIS: THE BASIC PATHOLOGY TO CONTROL Journal of Egyptian Society of Parasitology. 39(1), 85-98.
ELSAIED, NASHWA A, ABBAS, AYMN T, EL-BESHBISHI, SAMAR N and ELSHEIKHA, HANY M, 2009. Increased Helicobacter pylori-associated pathology in outbred mice coinfected with schistosomiasis. Parasitology research. 105(2), 297-9
ELSHAZLY, A.M., AZAB, M.S., ELBESHBISHI, S.N. and ELSHEIKHA, H.M., 2009. Hepatic hydatid disease: four case reports. Cases Journal. 2(1), 58
ELSAIED, N.A., HELALY, M.N. and ELSHEIKHA, H.M., 2009. Decisive research with C. elegans Veterinary Times. 39(27), 10-12
ELSHEIKHA, H.M., 2009. Treatment of Tick-Borne Diseases Veterinary Times. 39(33), 18-19
ELSHEIKHA, H.M., 2009. Has Sarcocystis neurona Dubey et al., 1991 (Sporozoa: Apicomplexa:Sarcocystidae) cospeciated with its hosts? Veterinary Parasitology. 163(4), 307-314.
ELSHEIKHA, H.M., 2009. Varroosis – Moving beyond headlines to clinical solutions for honeybees Veterinary Times. 39(18), 8.
ELSHEIKHA, H.M., 2009. Growing economic backlash demands Lungworm awareness Veterinary Times. 39(28), 12-14
ELSHEIKHA, H.M., 2009. Human health risk implication of ocular Myxoboliosis in fish. Veterinary Times. 39(9), 26-27
ELSHAZLY, A.M., AWAD, S.I., AZAB, M.S., ELSHEIKHA, H.M., ABDEL-GAWAD, A.G., KHALIL, H.H. and MORSY, T.A., 2009. Helminthes of synanthropic rodents (Rodentia: Muridae) from Dakahlia and Menoufia, Egypt. Journal Egyptian Society Parasitology. 38(3), 727-740
ELSHEIKHA, H.M., 2009. Soil nutrients and their implications Veterinary Times. 39(7), 16
ELSAIED, N.A., EL-DAHTORY, F. and ELSHEIKHA, H.M., 2009. Risks to Vets from Pesticides: Study into Organophosphates Veterinary Times. 39(39), 28-29
MASSEY, S., ELSHEIKHA, H.M. and MORSY, G.H., 2009. A CROSS-SECTIONAL STUDY OF INTESTINAL PARASITIC INFECTIONS OF THE EUROPEAN BADGERS IN WOODCHESTER PARK, SOUTH WEST ENGLAND Journal of Egyptian Society of Parasitology. 39(1), 171-182.
ELSHEIKHA, H.M. and KENDALL, N.R., 2009. Linking Theory to Practice in an Undergraduate Systems-Based Veterinary Curriculum: Students' Perspectives Journal of Veterinary Medical Education. 36(3), 291-296
ELSHEIKHA, H.M., 2009. Getting to Grips with Neospora Veterinary Times. 39(14), 30-31.
ELSAIED, N.A. and ELSHEIKHA, H.M., 2009. Lamproglena infestation in fish. Veterinary Times. 39(35), 6-8.
EL-DAHTORY, F. and ELSHEIKHA, H.M., 2009. Male infertility related to an aberrant karyotype 47,XYY: four case reports Cases Journal The Cases Journal. 2(1), 28
ELSHEIKHA HM and MORSY TA, 2009. Role Of Immune Response In Toxoplasma Gondii Tachyzoite-Bradyzote Stage Interconversion: A Janus In Determining Disease Outcome. Journal Of The Egyptian Society Of Parasitology. 39(2), 595-8
ELSHEIKHA HM, ABOUL-DAHAB MAO, ABDEL MABOUD AI and EL-SHERBINI ET, 2009. Prevalence And Risk Factors Of Toxoplasma Gondii Antibodies In Asymptomatic Egyptian Blood Donors. Journal Of The Egyptian Society Of Parasitology. 39(1 Suppl), 351-61
MASSEY S, ELSHEIKHA HM and MORSY GH, 2009. A Cross-Sectional Study Of Intestinal Parasitic Infections Of The European Badgers In Woodchester Park, South West England. Journal Of The Egyptian Society Of Parasitology. 39(1), 171-82
BOULD JG, ELSHEIKHA HM and MORSY TA, 2009. Avian Coccidiosis: The Basic Pathology To Control. Journal Of The Egyptian Society Of Parasitology. 39(1), 85-98
ELSHEIKHA HM, 2009. Has Sarcocystis Neurona Dubey Et Al., 1991 (Sporozoa: Apicomplexa: Sarcocystidae) Cospeciated With Its Intermediate Hosts? Veterinary Parasitology. 163(4), 307-14
ELSHEIKHA HM, AZAB MS, ABOUSAMRA NK, RAHBAR MH, ELGHANNAM DM and RAAFAT D, 2009. Seroprevalence Of And Risk Factors For Toxoplasma Gondii Antibodies Among Asymptomatic Blood Donors In Egypt. Parasitology Research. 104(6), 1471-6
ELSHEIKHA, HANY M and ELSHAZLY, ATTEF M, 2008. Preliminary observations on infection of brackish and fresh water fish by heterophyid encysted metacercariae in Egypt. Parasitology Research. 103(4), 971-977
ELSHEIKHA, H.M., 2008. Working towards cross-disciplinary approaches in veterinary medicine Veterinary Times. 38(24), 6
ELSHEIKHA, H.M., 2008. Cattle worming regimes: importance of developing immunity and rotation. Veterinary Times. 38(2), 12-13 (In Press.)
ELSHEIKHA, HANY M and ELSHAZLY, ATTEF M, 2008. Host-dependent variations in the seasonal prevalence and intensity of heterophyid encysted metacercariae (Digenea: Heterophyidea) in brackish water fish in Egypt. Veterinary Parasitology. 153(1-2), 65-72
ATTALLAH, A M, WAHBA, M A, ELSHEIKHA, H M, ABBAS, A T, ABDEL AZIZ, M M and EL-HEMALY, M A, 2008. Outcomes of Schistosoma mansoni infection in outbred albino mice exposed to Larvin contaminant. Parasitology Research. 103(3), 567-76
ELSHEIKHA, H.M., 2008. Unlimited potential of phylogenetics Veterinary Times. 38(19), 8
ELSHEIKHA, H M, 2008. Congenital toxoplasmosis: priorities for further health promotion action. Public Health. 122(4), 335-53
ELSHEIKHA, H.M., 2008. Recombination in SAG5 locus in Toxoplasma gondii: Phylogenetic evidence Veterinary Times. 38(9), 26-30
ELSHEIKHA, H.M., ELSHAZLY, A.M., EL-BESHBISHI, S.N., HAFEZ, A.O. and MORSY, T.A., 2008. Kinetics of eosinophilia and IgE production in experimantal murine toxocariasis Journal of Egyptian Society of Parasitology. 38(1), 53- 64 (In Press.)
ELSHEIKHA, H.M., 2008. Increasing threat to UK dogs of Angiostrongylus vasorum Veterinary Times. 38(26), 12-13
ELSHEIKHA, H.M., 2008. Coccidiosis Incidence, Control AND Epidemiology Put In Focus Veterinary Times. 39(51), 6-9
ELSHEIKHA, H.M., 2008. Canine vector-borne diseases — Treating this growing threat Veterinary Times. 38(11), 20-21
ELSHEIKHA, H.M., HUSSEIN, S.H. and RAHBAR, H.M., 2008. Clinico-pathological effects of Schistosoma mansoni infection associated with simultaneous exposure to malathion in Swiss outbred albino mice. Acta Tropica. 108, 11-19
MANSFIELD, L S, MEHLER, S, NELSON, K, ELSHEIKHA, H M, MURPHY, A J, KNUST, B, TANHAUSER, S M, GEARHART, P M, ROSSANO, M G, BOWMAN, D D, SCHOTT, H C and PATTERSON, J S, 2008. Brown-headed cowbirds (Molothrus ater) harbor Sarcocystis neurona and act as intermediate hosts. Veterinary Parasitology. 153(1-2), 24-43
ELSHEIKHA, H.M., 2008. Coccidiosis and cryptosporidiosis — growing performance complications Veterinary Times. 38(25), 8-9
ELSHEIKHA, H.M., MANSFIELD, L.S. and MORSY, G.H., 2008. Studies on besnoitiosis bennetti in miniature donkeys Journal of Egyptian Society of Parasitology. 38(1), 171-184
ELSHEIKHA, H.M. and ZHAO, X., 2008. Patterns and role of diversifying selection in the evolution of Toxoplasma gondii SAG5 locus. Parasitology Research. 103(1), 201-207
MANSFIELD, L.S., ROSSANO, M.G. and ELSHEIKHA, H.M., 2008. Sarcocystis neurona: determining life cycle and molecular evolutionary relationships In: cnia.inta.gov.ar.
ELSHAZLY, ATTEF M, ELSHEIKHA, HANY M, RAHBAR, MOHAMMAD H and AWAD, SOHA I, 2008. Comparison of three immunodiagnostic tests for experimental Heterophyes heterophyes infection in dogs. Veterinary Parasitology. 151(2-4), 196-202
ELSHEIKHA,, 2008. Safer food for pregnant women: Practices and risks. Public Health. 122, 1407-1409
ELSHEIKHA, H.M., ABBAS, A.T., ABDEL AZIZ, M.M. and ELSHABINY, L.M., 2008. Therapeutic efficacy of chicken egg yolk immunoglobulins against Mycoplasma gallisepticum infection in chickens. International Journal of Poultry Science. 7(6), 548-554.
HANY M. ELSHEIKHA, 2008. Observations from Anguillicola crassus found in European Eels Veterinary Times. 38(37), 22-23
ELSHAZLY AM, AWAD SI, AZAB MS, ELSHEIKHA HM, ABDEL-GAWAD AGE, KHALIL HHM and MORSY TA, 2008. Helminthes Of Synanthropic Rodents (Rodentia: Muridae) From Dakahlia And Menoufia, Egypt. Journal Of The Egyptian Society Of Parasitology. 38(3), 727-40
ELSHEIKHA HM, MANSFIELD LS and MORSY GH, 2008. Studies On Besnoitiosis Bennetti In Miniature Donkeys. Journal Of The Egyptian Society Of Parasitology. 38(1), 171-84
ELSHEIKHA HM, EL-BESHBISHI SN, EL-SHAZLY AM, HAFEZ AO and MORSY TA, 2008. Kinetics Of Eosinophilia And Ige Production In Experimental Murine Toxocariasis. Journal Of The Egyptian Society Of Parasitology. 38(1), 53-64
ELSHEIKHA, HANY M, 2007. Heterophyosis: risk of ectopic infection. Veterinary Parasitology. 147(3-4), 341-2
ELSHEIKHA, HNY M, EL-BESHBISHI, SAMAR N and MANSFIELD, LINDA S, 2007. Ultrastructure characteristics of Besnoitia darlingi tachyzoites Brumpt, 1913 (Protozoa: Sarcocystidae) of the Michigan strain MIBD1. Journal of the Egyptian Society of Parasitology. 37(3), 989-97
ELSHEIKHA, H. M., 2007. Besnoitia bennetti infection in miniature donkeys: An emerging protozoan of increasing concern Veterinary Parasitology. VOL 145(NUMBER 3-4), 390-391
EL SHAZLY, ATEF M A, SOLTAN, DOAA M, EL-SHEIKHA, HANY M, SADEK, GEHAN S and MORSY, AYMAN T A, 2007. Correlation of ELISA copro-antigen and oocysts count to the severity of cryptosporidiosis parvum in children. Journal of the Egyptian Society of Parasitology. 37(1), 107-20
ELSHEIKHA, HANY M and SHEASHAA, HUSSEIN A, 2007. Epidemiology, pathophysiology, management and outcome of renal dysfunction associated with plasmodia infection. Parasitology Research. 101(5), 1183-90
ABU ELWAFA, S.A., ELSHEIKHA, H.M. and ELSHAZLY, A.M., 2007. Cryptosporidiosis in a flock of sheep and their nomad shepherds In: The Fifth International Scientific Conference, Mansoura University, Egypt.
ELSHEIKHA, H. M., 2007. What Makes Sarcocystis neurona So Special? Journal of Equine Veterinary Science. VOL 27(NUMBER 3), 99-100
ELSHEIKHA, HANY M and MANSFIELD, LINDA S, 2007. Molecular typing of Sarcocystis neurona: current status and future trends. Veterinary Parasitology. 149(1-2), 43-55
ZALATA, A., YAHIA, S., EL-BAKARY, A. and ELSHEIKHA, H. M., 2007. Corrigendum to "Increased DNA damage in children caused by passive smoking as assessed by comet assay and oxidative stress" [Mutation Research 629 (2007) 140-147] Mutation Research. VOL 632(NUMBER 1-2), 126
ELSHEIKHA, H. M., 2007. Heterophyosis: Risk of ectopic infection Veterinary Parasitology. VOL 147(NUMBER 3-4), 341-342
EL-NAHAS, HALA A, EL-BESHBISHI, SAMAR N, AZAB, MANAR S, ZAALOUK, TAREK KH, ELSHEIKHA, HANY M, SALEH, ABDEL-BASET M and EL-SHAZLY, ATEF M, 2007. Diagnostic criteria for house dust mites sensitized allergic patients. Journal of the Egyptian Society of Parasitology. 37(3 Suppl), 1113-24
ELSHAZLY, ATTEF M, ELSHEIKHA, HANY M, SOLTAN, DOAA M, MOHAMMAD, KHAIRY A and MORSY, TOSSON A, 2007. Protozoal pollution of surface water sources in Dakahlia Governorate, Egypt. Journal of the Egyptian Society of Parasitology. 37(1), 51-64
ELSHEIKHA, HANY M, 2007. Besnoitia bennetti infection in miniature donkeys: an emerging protozoan of increasing concern. Veterinary Parasitology. 145(3-4), 390-1
ELSHAZLY, ATEF M, SOLTAN, DOAA M, ELSHEIKHA, HANY M, MORSY, GAZAA H and MORSY, TOSSON A, 2007. Host-induced phenotypic differences in Egyptian Heterophyes heterophyes (Digenea: Heterophyidae). Journal of the Egyptian Society of Parasitology. 37(3), 815-24
MANSFIELD, L S, BELL, J A, WILSON, D L, MURPHY, A J, ELSHEIKHA, H M, RATHINAM, V A K, FIERRO, B R, LINZ, J E and YOUNG, V B, 2007. C57BL/6 and congenic interleukin-10-deficient mice can serve as models of Campylobacter jejuni colonization and enteritis. Infection and Immunity. 75(3), 1099-115
ELSHEIKHA, H. M. and SHEASHAA, H. A., 2007. Epidemiology, pathophysiology, management and outcome of renal dysfunction associated with plasmodia infection Parasitology Research. VOL 101(NUMBER 5), 1183-1190
EL SHEIKHA, HANY M, HUSSEIN, HUSSEIN S, MONIB, MOHAMMAD EL-SALAHY M and MANSFIELD, LINDA S, 2007. Observations on besnoitiosis in Virginia opossum (Didelphis virginiana) from Michigan, USA. Journal of the Egyptian Society of Parasitology. 37(1), 1-16
ZALATA, A., YAHIA, S., EL-BAKARY, A. and ELSHEIKHA, H. M., 2007. Increased DNA damage in children caused by passive smoking as assessed by comet assay and oxidative stress Mutation Research. VOL 629(NUMBER 2), 140-147
ELSHEIKHA, H. M., SOLTAN, D. M. and EL GARHY, M. F., 2006. INFERENCE OF MOLECULAR PHYLOGENY OF SARCOCYSTIS FELIS (SARCOCYSTIDAE) FROM CATS BASED ON NUCLEAR-ENCODED RIBOSOMAL GENE SEQUENCES Journal of Egyptian Society of Parasitology. VOL 36(NUMB 2), 441-444
MAREI, H. E. S. and ELSHEIKHA, H. M., 2006. ENHANCEMENT OF VETERINARY IMAGE-BASED COURSES EDUCATION BY ONLINE MULTIMEDIA INTERACTIVE PRESENTATIONS 4th. 7
ATTALLAH, A. M., ABBAS, A. T., DESSOUKY, M. I., EL-EMSHATY, H. M. and ELSHEIKHA, H. M., 2006. Susceptibility of neonate mice born to Schistosoma mansoni-infected and noninfected mothers to subsequent S. mansoni infection Parasitology Research. VOL 99(NUMBER 2), 137-145
ELSHEIKHA, H. M., IBRAHIM, M. S., SOLIMAN, M., ABBAS, A. T., MORSY, G. H. and ABDEL AZIZ, M. M., 2006. IN VITRO EVALUATION OF BOVINE TURBINATE CELLS AND SARCOCYSTIS FALCATULA PROLIFERATION IN RESPONSE TO SERUM-FREE MEDIUM AND OTHER MEDIA SUPPLEMENTS Journal of Egyptian Society of Parasitology. VOL 36(NUMB 2), 517-530
ELSHEIKHA, H. M., MURPHY, A. J., TREMBLEY, S. J., MANSFIELD, L. S., GHANAM, M. S. and EL GARHY, M. F., 2006. MOLECULAR AND MICROSCOPIC TECHNIQUES FOR DETECTION OF SARCOCYSTIS NEURONA SPORO-CYSTS IN FECAL SAMPLES Journal of Egyptian Society of Parasitology. VOL 36(NUMB 2), 713-725
ELSHEIKHA, H. M., SCHOTT, H. C. and MANSFIELD, L. S., 2006. Genetic Variation among Isolates of Sarcocystis neurona, the Agent of Protozoal Myeloencephalitis, as Revealed by Amplified Fragment Length Polymorphism Markers Infection and Immunity. VOL 74(NUMB 6), 3448-3454
ELSHEIKHA, H. M., KENNEDY, F. A., MURPHY, A. J., SOLIMAN, M. and MANSFIELD, L. S., 2006. SARCOCYSTOSIS OF SARCOCYSTIS FELIS IN CATS Journal of Egyptian Society of Parasitology. VOL 36(NUMB 3), 1071-1086
ELSHEIKHA, H. M., ROSENTHAL, B. M., MURPHY, A. J., DUNAMS, D. B., NEELIS, D. A. and MANSFIELD, L. S., 2006. Generally applicable methods to purify intracellular coccidia from cell cultures and to quantify purification efficacy using quantitative PCR Veterinary Parasitology. VOL 135(NUMBER 3-4), 223-234
ELSHEIKHA, H. M., MACKENZIE, C. D., ROSENTHAL, B. M., MARTENIUK, J. V., STEFICEK, B., WINDSOR, S., SAEED, A. M. and MANSFIELD, L. S., 2005. An Outbreak of Besnoitiosis in Miniature Donkeys Journal of Parasitology. VOL 91(NUMB 4), 877-881
ELSHEIKHA, H. M., MURPHY, A. J. and MANSFIELD, L. S., 2005. Phylogenetic congruence of Sarcocystis neurona Dubey et al., 1991 (Apicomplexa: Sarcocystidae) in the United States based on sequence analysis and restriction fragment length polymorphism (RFLP) Systematic Parasitology. VOL 61(NUMBER 3), 191-202
MANSFIELD, L.S. and ELSHEIKHA, H.M., 2005. Positive selection in the immuno-dominant surface antigen 1 (sag1) of sarcocystis neurona, agent of epm: potential as a diagnostic reagent and as a component of a sub-unit vaccine US20050260692 01/01/1900 00:00:00
ELSAEID, N., NICHOLS, E., MUSTON, J., ELSHEIKHA, H.M., EVERSOLE, R.R., ESTRY, D., WILLIAMS, J.F. and MACKENZIE, C.D., 2004. The hemostatic properties of different formulations of chitosan in rats FASEB JOURNAL. 18(4), A196-A196
ELSHEIKHA, H. M. and MANSFIELD, L. S., 2004. Sarcocystis neurona Major Surface Antigen Gene 1 (SAG1) Shows Evidence of Having Evolved under Positive Selection Pressure Parasitology Research. VOL 92(NUMB 1), 4
ELSHEIKHA, HANY M, MURPHY, ALICE J and MANSFIELD, LINDA S, 2004. Prevalence of Sarcocystis species sporocysts in Northern Virginia opossums (Didelphis virginiana). Parasitology Research. 93(5), 427-31
ELSHEIKHA, H. M., KENNEDY, F. A., MURPHY, A. J. and MANSFIELD, L. S., 2004. Sarcocystis Cysts Associated with Meningeoencephalomyelitis in a Cat (Felis domesticus) AAVP Meeting.
MACKENZIE, C.D., NICHOLS, E., ELSAEID, N., HAUT, R., ELSHEIKHA, H., EVERSOLE, R.R. and WILLIAMS, J.F., 2004. The effects of different chitin and chitosan preparations on wound healing in rats FASEB JOURNAL. 18(5), A940-A940
ELSHEIKHA, HANY M, MURPHY, ALICE J and MANSFIELD, LINDA S, 2004. Viability of Sarcocystis neurona sporocysts after long-term storage. Veterinary Parasitology. 123(3-4), 257-64
ELSHEIKHA, HANY M and MANSFIELD, LINDA S, 2004. Determination of the activity of sulfadiazine against Besnoitia darlingi tachyzoites in cultured cells. Parasitology Research. 93(5), 423-6
ELSHEIKHA, HANY M, MURPHY, ALICE J and MANSFIELD, LINDA S, 2004. Prevalence of and risk factors associated with the presence of Sarcocystis neurona sporocysts in opossum (Didelphis virginiana) from Michigan: a retrospective study. Veterinary Parasitology. 125(3-4), 277-86
ELSHEIKHA, HANY M, MURPHY, ALICE J, FITZGERALD, SCOTT D, MANSFIELD, LINDA S, MASSEY, JEFFREY P and SAEED, MAHDI A, 2003. Purification of Sarcocystis neurona sporocysts from opossum (Didelphis virginiana) using potassium bromide discontinuous density gradient centrifugation. Parasitology Research. 90(2), 104-9
ELSHEIKHA, HANY M, SAEED, MAHDI A, FITZGERALD, SCOTT D, MURPHY, ALICE J and MANSFIELD, LINDA S, 2003. Effects of temperature and host cell type on the in vitro growth and development of Sarcocystis falcatula. Parasitology Research. 91(1), 22-6
MAIDHOF, HEINRICH, GUERRA, BEATRIZ, ABBAS, SASCHA, ELSHEIKHA, HANY M, WHITTAM, THOMAS S and BEUTIN, LOTHAR, 2002. A multiresistant clone of Shiga toxin-producing Escherichia coli O118:[H16] is spread in cattle and humans over different European countries. Applied and Environmental Microbiology. 68(12), 5834-42
SALAH ABU ELWAFA, NISREEN EZZ EL-DIEN, ELSHEIKHA HM, 1999. Description of Trichodina cogwheeli n. sp., and other newly recorded ectoparasites from Egyptian fresh water fish Beni-Suef Vet Med J.. 2, 203-216
ELSHEIKHA HM and KENDALL NR, 1. Linking Theory To Practice In An Undergraduate Veterinary Curriculum: Students' Perspectives. Journal Of Veterinary Medical Education. 36(3), 291-6
ELSHEIKHA, H.M., Vector vigilance: tick-borne diseases Veterinary Times. 39(19), 12-13.
ELSHEIKHA, H.M., Diagnosis and treatment of heartworm in small animals Veterinary Times. 39(31), 14-18
ELSHEIKHA, H.M. and ROSSANO, M.G., Evidence-based approach is wise Veterinary Times. 39(37), 6-10
ELSHEIKHA HM, DODD N and HAIG D, Toxoplasma gondii and heart disease Veterinary Times. 42(39), 12-14

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