Contact

• workRoom A11b Clinical Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 951 6751
• Mark.Dunning@nottingham.ac.uk

Teaching Summary

I deliver lectures, practicals and facilitated sessions on the majority of the clinical modules including urinary, LCB, cardiotrespiratory, endocrinology and gastroenterology.

I previously ran the final year small animal referral rotation which focused on developing clinical reasoning skills and practical techniques using referral cases to enable a deep appreciation of clinical medicine.

Research Summary

One of my current areas of research activity is in the development of non-invasive diagnostic techniques and the validation of point-of-care methodologies to expand the possibilities for cases to be… read more

Selected Publications

• GREENHALGH SN, REEVE JA, JOHNSTONE T, GOODFELLOW MR, DUNNING MD, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2014. Long-term survival and quality of life in dogs with clinical signs associated with a congenital portosystemic shunt after surgical or medical treatment. Journal of the American Veterinary Medical Association. 245(5), 527-33
• STEINBACH, SARAH M. L., STURGESS, CHRISTOPHER P., DUNNING, MARK D. and NEIGER, RETO, 2015. Use of a Microsoft Excel based add-in program to calculate plasma sinistrin clearance by a two-compartment model analysis in dogs RESEARCH IN VETERINARY SCIENCE. 100, 263-264
• CHIKAZAWA, S. and DUNNING, M. D., 2016. A review of anaemia of inflammatory disease in dogs and cats JOURNAL OF SMALL ANIMAL PRACTICE. 57(7), 348-353
• JENNIFER CARTWRIGHT, MALCOLM COBB and MARK DUNNING, 2019. A pilot study evaluating the monitoring of canine diabetes mellitus in primary care practice Veterinary Record Open. (In Press.)

• View all publications

Current Research

One of my current areas of research activity is in the development of non-invasive diagnostic techniques and the validation of point-of-care methodologies to expand the possibilities for cases to be investigated and diseases monitored in primary care practice. A number of current projects are being carried out including those evaluating remote markers of disease activity in blood, urine and faeces.

In addition, allied to the development of techniques to facilitate the effective investigation and management of cases in primary-care practice, we are developing research projects to address important questions arising from problems encountered in primary care practice. These are developing in liaison with the evidence-based medicine group. Our network is currently working directly with primary-care practices avoiding extrapolating anticipated outcomes from referral populations.

A further area of my research activity is in the development of owner and breeder focused canine research. This approach has been designed to empower and enhance owner and breeder involvement in prospective research projects. The ethos is that those people owning and breeding dogs have fundamental questions over the health of their animals. This approach is therefore dedicated to facilitating the development of these concerns into active research projects. At present we are collaborating with a number of breed groups and involve a number of primary research and clinical research groups within the School of Veterinary medicine and Science and the University of Nottingham and other groups in the UK, along with groups in the USA and Europe. One particular area of breed-specific research is into the apparent breed predispositions to the develop and outcome of canine osteosarcoma and other cancers. This is in collaboration with a number of groups both within and outside of the University of Nottingham. This research is allied to similar research in humans and in breeds in both the USA and Europe.

In addition to these areas, I am passionate about student engagement with research and run clinical research projects for students who are keen to experience research. These projects are designed around the students individual areas of interest. These projects have invariably led to students presenting their research at international conferences and writing their research up for publication in peer reviewed journals.

Past Research

My historic research background is in experimental neuroscience. This primarily investigated the potential for glial cells to be labeled with a number of different paramagnetic contrast agents in vitro prior to transplantation into the CNS. The impact of this labeling on the function of the glial cells was assessed both in vitro and in vivo. The ability of the fates of those labeled cells to be followed in vivo using MRI was also investigated at various time points.

Other historic areas of clinical research have included the use of radiotherapy to treat cats with acromegaly, the comparative outcome of dogs managed with medical and surgical approaches that are suffering with portosystemic shunts, identifying therapeutic markers in dogs with nasal tumours and clotting disorders in Weimaraners.

• SIMPSON, SIOBHAN, DUNNING, MARK, DE BROT, SIMONE, ALIBHAI, AZIZA, BAILEY, CLARA, WOODCOCK, CORINNE L, MESTAS, MADELINE, AKHTAR, SHAREEN, JEYAPALAN, JENNIE N, LOTHION-ROY, JENNIFER, EMES, RICHARD D, ALLEGRUCCI, CINZIA, RIZVANOV, ALBERT A, MONGAN, NIGEL P and RUTLAND, CATRIN S, 2020. Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds. Cancers. 12(9),
• MOONEY, CARMEL T., SHIEL, ROBERT E., SEKIYA, MARY, DUNNING, MARK and GUNN, EILIDH, 2020. A Preliminary Study of the Effect of Hyperadrenocorticism on Calcium and Phosphate Concentrations, Parathyroid Hormone and Markers of Bone Turnover in Dogs FRONTIERS IN VETERINARY SCIENCE. 7,
• SIMPSON, SIOBHAN, DUNNING, MARK, DE BROT, SIMONE, ALIBHAI, AZIZA, BAILEY, CLARA, WOODCOCK, CORINNE L., MESTAS, MADELINE, AKHTAR, SHAREEN, JEYAPALAN, JENNIE N., LOTHION-ROY, JENNIFER, EMES, RICHARD D., ALLEGRUCCI, CINZIA, RIZVANOV, ALBERT A., MONGAN, NIGEL P. and RUTLAND, CATRIN S., 2020. Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds CANCERS. 12(9),
• WESTON, PHILIPPA, MORALES, CARLES, DUNNING, MARK, PARRY, ANDREW and CARRERA, INES, 2020. Susceptibility weighted imaging at 1.5 Tesla magnetic resonance imaging in dogs: Comparison with T2*-weighted gradient echo sequence and its clinical indications VETERINARY RADIOLOGY & ULTRASOUND. 61(5), 566-576
• CROFT, RACHEL, CLEMENTI, ELISABETTA, BVM, HELEN FARMER, BVM, RACHEL WHALLEY, DUNNING, MARK and FIRTH, AVA, 2020. Retrospective evaluation of Vitis vinifera ingestion in dogs presented to emergency clinics in the UK (2012-2016): 606 Cases JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE.
• SHUTTLEWORTH A, DUNNING M, WRIGHT I and ELSHEIKHA HM, 2019. Survey-based pilot study into the chosen therapy and prophylaxis used by UK primary care veterinary surgeons against canine angiostrongylosis. Veterinary parasitology, regional studies and reports. 14, 144-149
• ALLERTON, FERGUS, FISHWICK, JOHN, PATERSON, SUSAN, WELLER, RENATE, BATTERSBY, IAN, DOYLE, RONAN, GOULD, DAVID, CADDY, SARAH, DUNNING, MARK, FEATHERSTONE, HEIDI J, HARDY, JON, KENT, ANDREW, PEDRO, BRIGITE, SMITH, KINLEY, SWINBOURNE, FAYE, HARRIS, JAMES, HEINRICH, CHRISTINE, LAU-GILLARD, PERI, LOEFFLER, ANETTE, MADDINSON, REBECCA, MASON, CARLY, RAMSEY, IAN, RIDYARD, ALISON, ROBIN, LOUISE, SCUDDER, CHRISTOPHER, SETH, MAYANK, TAPPIN, SIMON, SINGLETON, DAVID, SMITH, HEATHER, SOUTHERDEN, PETER, WARLAND, JAMES, WHITEHEAD, MARTIN and WILLIAMS, JOHN, 2019. Call for coordinated antimicrobial approach at veterinary diagnostic laboratories. The Veterinary record. 184(26), 805-806
• POSPORIS C, BELTRAN E, DUNNING M, ESPADAS I, GILLESPIE S, BARRY AT and WESSMANN A, 2019. Prognostic Factors for Recovery of Vision in Canine Optic Neuritis of Unknown Etiology: 26 Dogs (2003-2018). Frontiers in veterinary science. 6, 415
• JAFFEY JA, PAVLICK M, WEBSTER CR, MOORE GE, MCDANIEL KA, BLOIS SL, BRAND EM, REICH CF, MOTSCHENBACHER L, HOSTNIK ET, SU D, LIDBURY JA, RAAB O, CARR SV, MABRY KE, FOX-ALVAREZ W, TOWNSEND S, PALERMO S, NAKAZONO Y, OHNO K, VANEERDE E, FIETEN H, HULSMAN AH, COOLEY-LOCK K, DUNNING M, KISIELEWICZ C, ZOIA A, CALDIN M, CONTI-PATARA A, ROSS L, MANSFIELD C, LYNN O, CLAUS MA, WATSON PJ, SWALLOW A, YOOL DA, GOMMEREN K, KNOPS M, CEPLECHA V, DE ROOSTER H, LOBETTI R, DOSSIN O, JOLIVET F, PAPAZOGLOU LG, PAPPALARDO MCF, MANCZUR F, DUDÁS-GYÖRKI Z, O'NEILL EJ, MARTINEZ C, GAL A, OWEN RL, GUNN E, BROWN K, HARDER LK, GRIEBSCH C, ANFINSEN KP, GRON TK, MARCHETTI V, HEILMANN RM, PAZZI P and DECLUE AE, 2019. Effect of clinical signs, endocrinopathies, timing of surgery, hyperlipidemia, and hyperbilirubinemia on outcome in dogs with gallbladder mucocele. Veterinary journal (London, England : 1997). 251, 105350
• DOR C, GAJANAYAKE I, KORTUM A, DAY MJ, TAPPIN S, HARRIS B, BATTERSBY I, WALKER D, GLANEMANN B, MYATT P, DUNNING M and BEXFIELD N, 2019. Characterisation and outcome of idiopathic pyogranulomatous lymphadenitis in 64 English springer spaniel dogs. The Journal of small animal practice. 60(9), 551-558
• POLLEDO L, GRINWIS GCM, GRAHAM P, DUNNING M and BAIKER K, 2018. Pathological Findings in the Pituitary Glands of Dogs and Cats. Veterinary pathology. 55(6), 880-888
• ALLERTON F, SWINBOURNE F, BARKER L, BLACK V, KATHRANI A, TIVERS M, HENRIQUES T, KISIELEWICZ C, DUNNING M and KENT A, 2018. Gall bladder mucoceles in Border terriers. Journal of veterinary internal medicine. 32(5), 1618-1628
• SIMPSON S, DUNNING MD, BROWNLIE S, PATEL J, GODDEN M, COBB M, MONGAN NP and RUTLAND CS, 2017. Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy. BioMed research international. 2016, 6374082
• SIMPSON S, DUNNING MD, DE BROT S, GRAU-ROMA L, MONGAN NP and RUTLAND CS, 2017. Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics. Acta veterinaria Scandinavica. 59(1), 71
• DUNNING M, MAY J, ADAMANY J, HEPTINSTALL S and FOX S, 2017. A Remote Assay for Measuring Canine Platelet Activation and the Inhibitory Effects of Antiplatelet Agents. Journal of veterinary internal medicine. 32(1), 119-127
• ADAMANY JL, CROSS GF, GARDNER D and DUNNING MD, 2017. Preliminary investigation of urine N-telopeptide concentration as a biomarker of bone resorption in dogs receiving glucocorticoids. The Journal of small animal practice. 58(7), 403-407
• DUNNING M, 2017. Improving IBD in dogs through exercise. The Veterinary record. 180(9), 222-223
• 2016. Polyglandular endocrinopathy type II (Schmidt's syndrome) in a Dobermann pinscher. The Journal of small animal practice. (In Press.)
• CHIKAZAWA, S. and DUNNING, M. D., 2016. A review of anaemia of inflammatory disease in dogs and cats JOURNAL OF SMALL ANIMAL PRACTICE. 57(7), 348-353
• STEINBACH, SARAH M. L., STURGESS, CHRISTOPHER P., DUNNING, MARK D. and NEIGER, RETO, 2015. Use of a Microsoft Excel based add-in program to calculate plasma sinistrin clearance by a two-compartment model analysis in dogs RESEARCH IN VETERINARY SCIENCE. 100, 263-264
• GREENHALGH SN, REEVE JA, JOHNSTONE T, GOODFELLOW MR, DUNNING MD, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2014. Long-term survival and quality of life in dogs with clinical signs associated with a congenital portosystemic shunt after surgical or medical treatment. Journal of the American Veterinary Medical Association. 245(5), 527-33
• CHARLESWORTH TM, DUNNING M, SCASE TJ and ANDERSON DM, 2012. Colonic vascular ectasia (angiodysplasia) in a juvenile dog. The Journal of small animal practice. 54(1), 36-9
• BELSHAW Z, CONSTANTIO-CASAS F, BREARLEY MJ, DUNNING MD, HOLMES MA and DOBSON JM, 2011. Cox-2 Expression And Outcome In Canine Nasal Carcinomas Treated With Hypofractionated Radiotherapy. Veterinary And Comparative Oncology. 9(2), 141-8
• GREENHALGH SN, DUNNING MD, MCKINLEY TJ, GOODFELLOW MR, KELMAN KR, FREITAG T, O'NEILL EJ, HALL EJ, WATSON PJ and JEFFERY ND, 2010. Comparison Of Survival After Surgical Or Medical Treatment In Dogs With A Congenital Portosystemic Shunt. Journal Of The American Veterinary Medical Association. 236(11), 1215-20
• DUNNING MD, AVERIS GF, PATTINSON H, TARGETT M, CADE S and HERRTAGE ME, 2009. Haemophilia A (Factor Viii Deficiency) In A Litter Of Weimaraners. The Journal Of Small Animal Practice. 50(7), 357-9
• DUNNING MD, LOWRIE CS, BEXFIELD NH, DOBSON JM and HERRTAGE ME, 2009. Exogenous Insulin Treatment After Hypofractionated Radiotherapy In Cats With Diabetes Mellitus And Acromegaly. Journal Of Veterinary Internal Medicine / American College Of Veterinary Internal Medicine. 23(2), 243-9
• MELLOR PJ, FETZ K, MAGGI RG, HAUGLAND S, DUNNING M, VILLIERS EJ, MELLANBY RJ, WILLIAMS D, BREITSCHWERDT E and HERRTAGE ME, 2006. Alpha1-Proteinase Inhibitor Deficiency And Bartonella Infection In Association With Panniculitis, Polyarthritis, And Meningitis In A Dog. Journal Of Veterinary Internal Medicine / American College Of Veterinary Internal Medicine. 20(4), 1023-8
• DUNNING MD, KETTUNEN MI, FFRENCH CONSTANT C, FRANKLIN RJM and BRINDLE KM, 2006. Magnetic Resonance Imaging Of Functional Schwann Cell Transplants Labelled With Magnetic Microspheres. Neuroimage. 31(1), 172-80
• DUNNING MD, LAKATOS A, LOIZOU L, KETTUNEN M, FFRENCH-CONSTANT C, BRINDLE KM and FRANKLIN RJM, 2004. Superparamagnetic Iron Oxide-Labeled Schwann Cells And Olfactory Ensheathing Cells Can Be Traced In Vivo By Magnetic Resonance Imaging And Retain Functional Properties After Transplantation Into The Cns. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 24(44), 9799-810
• PENDERIS J, WOODRUFF RH, LAKATOS A, LI W, DUNNING MD, ZHAO C, MARCHIONNI M and FRANKLIN RJM, 2003. Increasing Local Levels Of Neuregulin (Glial Growth Factor-2) By Direct Infusion Into Areas Of Demyelination Does Not Alter Remyelination In The Rat Cns. The European Journal Of Neuroscience. 18(8), 2253-64
• DUNNING, M and STONEHEWER, J, 2002. Urinary Tract Infections In Small Animals: Pathophysiology And Diagnosis In Practice. 24(8), 418-+
• DUNNING, M and STONEHEWER, J, 2002. Urinary Tract Infections In Small Animals: Therapeutic Options And Management Of Problem Cases In Practice. 24(9), 518-+
• LASCELLES BD, DAVISON L, DUNNING M, BRAY JP and WHITE RA, 1998. Use Of Omental Pedicle Grafts In The Management Of Non-Healing Axillary Wounds In 10 Cats. The Journal Of Small Animal Practice. 39(10), 475-80