KEVIN D SINCLAIR, 2018. When maternal periconceptional diet affects neurological development, it’s time to think Proceedings of the National Academy of Sciences of the United States of America. WATKINS AJ, DIAS I, TSURO H, ALLEN D, EMES RD, MORETON J, WILSON R, INGRAM RJM and SINCLAIR KD, 2018. Paternal diet programs offspring health through sperm- and seminal plasma-specific pathways in mice. Proceedings of the National Academy of Sciences of the United States of America. (In Press.)
CLARE CE, BRASSINGTON AH, KWONG WY and SINCLAIR KD, 2018. One-Carbon Metabolism: Linking Nutritional Biochemistry to Epigenetic Programming of Long-Term Development. Annual review of animal biosciences. (In Press.)
HUNTRISS J, BALEN AH, SINCLAIR KD, BRISON DR, PICTON HM and , 2018. Epigenetics and Reproductive Medicine: Scientific Impact Paper No. 57. BJOG : an international journal of obstetrics and gynaecology. 125(13), e43-e54 CHOI M, GENEREUX DP, GOODSON J, AL-AZZAWI H, ALLAIN SQ, SIMON N, PALASEK S, WARE CB, CAVANAUGH C, MILLER DG, JOHNSON WC, SINCLAIR KD, STÖGER R and LAIRD CD, 2017. Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells. PLoS genetics. 13(11), e1007060 CORR SA, GARDNER DS, LANGLEY-HOBBS S, NESS MG, KITCHENER AC and SINCLAIR KD, 2017. Radiographic assessment of the skeletons of Dolly and other clones finds no abnormal osteoarthritis. Scientific reports. 7(1), 15685 SINCLAIR, KEVIN, RUTHERFORD, KENNETH, WALLACE, JACQUELINE, BRAMELD, JOHN, STÖGER, REINHARD, ALBERIO, RAMIRO, SWEETMAN, DYLAN, GARDNER, DAVID, PERRY, VIV, ADAM, CLARE and OTHERS, 2016. Epigenetics and developmental programming of welfare and production traits in farm animals Reproduction, Fertility and Development. SINCLAIR KD, CORR SA, GUTIERREZ CG, FISHER PA, LEE JH, RATHBONE AJ, CHOI I, CAMPBELL KH and GARDNER DS, 2016. Healthy ageing of cloned sheep. Nature communications. 7, 12359 SINCLAIR, KD, RUTHERFORD, KMD, WALLACE, JM, BRAMELD, JM and ET AL., 2016. Epigenetics and developmental programming of welfare and production traits in farm animals. Reproduction, fertility, and development. 28(10), 1443-1478 GREGSON E, WEBB R, SHELDRICK EL, CAMPBELL BK, MANN GE, LIDDELL S and SINCLAIR KD, 2016. Molecular determinants of a competent bovine corpus luteum: first- vs final-wave dominant follicles. Reproduction (Cambridge, England). 151(6), 563-75 LEA RG, AMEZAGA MR, LOUP B, MANDON-PÉPIN B, STEFANSDOTTIR A, FILIS P, KYLE C, ZHANG Z, ALLEN C, PURDIE L, JOUNEAU L, COTINOT C, RHIND SM, SINCLAIR KD and FOWLER PA, 2016. The fetal ovary exhibits temporal sensitivity to a 'real-life' mixture of environmental chemicals. Scientific reports. 6, 22279 XU J and SINCLAIR KD, 2015. One-carbon metabolism and epigenetic regulation of embryo development. Reproduction, fertility, and development. 27(4), 667-76 DRAKE AJ, O'SHAUGHNESSY PJ, BHATTACHARYA S, MONTEIRO A, KERRIGAN D, GOETZ S, RAAB A, RHIND SM, SINCLAIR KD, MEHARG AA, FELDMANN J and FOWLER PA, 2015. In utero exposure to cigarette chemicals induces sex-specific disruption of one-carbon metabolism and DNA methylation in the human fetal liver. BMC medicine. 13, 18 DUNFORD, LOUISE J., SINCLAIR, KEVIN D., KWONG, WING Y., STURROCK, CRAIG, CLIFFORD, BETHAN L., GILES, TOM C. and GARDNER, DAVID S., 2014. Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development: Faseb Journal Faseb Journal. 28(11), 4880-4892 SCHAEDLICH K, SCHMIDT JS, KWONG WY, SINCLAIR KD, KURZ R, JAHNKE HG and FISCHER B, 2014. Impact of di-ethylhexylphthalate exposure on metabolic programming in P19 ECC-derived cardiomyocytes. Journal of applied toxicology : JAT. 35(7), 861-9 DUNFORD LJ, SINCLAIR KD, KWONG WY, STURROCK C, CLIFFORD BL, GILES TC and GARDNER DS, 2014. Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(11), 4880-92 ALBERIO R and SINCLAIR KD, 2014. Can we make a placenta in the Petri dish? Reproduction (Cambridge, England). 147(5), E3 WATKINS AJ and SINCLAIR KD, 2014. Paternal low protein diet affects adult offspring cardiovascular and metabolic function in mice. American journal of physiology. Heart and circulatory physiology. 306(10), H1444-52 SINCLAIR KD, GARNSWORTHY PC, MANN GE and SINCLAIR LA, 2013. Reducing dietary protein in dairy cow diets: implications for nitrogen utilization, milk production, welfare and fertility. Animal : an international journal of animal bioscience. 8(2), 262-74 JOSEPH, C., HUNTER, M.G., SINCLAIR, K.D. and ROBINSON, R.S., 2012. The expression, regulation and function of secreted protein, acidic, cysteine-rich (sparc) in the follicle-luteal transition Reproduction. 144(3), 361-372 BELLINGHAM M, FIANDANESE N, BYERS A, COTINOT C, EVANS NP, POCAR P, AMEZAGA MR, LEA RG, SINCLAIR KD, RHIND SM and FOWLER PA, 2012. Effects of exposure to environmental chemicals during pregnancy on the development of the male and female reproductive axes. Reproduction in domestic animals = zuchthygiene. 47 Suppl 4, 15-22 PRING SR, OWEN M, KING JR, SINCLAIR KD, WEBB R, FLINT APF and GARNSWORTHY PC, 2012. A mathematical model of the bovine oestrous cycle: simulating outcomes of dietary and pharmacological interventions. Journal of theoretical biology. 313, 115-26 MALONEY, CHRISTOPHER A, HAY, SUSAN M, YOUNG, LORAINE E, SINCLAIR, KEVIN D and REES, WILLIAM D, 2011. A methyl-deficient diet fed to rat dams during the peri-conception period programs glucose homeostasis in adult male but not female offspring. The Journal of nutrition. 141(1), 95-100 FOWLER PA, BELLINGHAM M, SINCLAIR KD, EVANS NP, POCAR P, FISCHER B, SCHAEDLICH K, SCHMIDT J, AMEZAGA MR, BHATTACHARYA S, RHIND SM and O'SHAUGHNESSY PJ, 2011. Impact Of Endocrine-Disrupting Compounds (Edcs) On Female Reproductive Health. Molecular And Cellular Endocrinology. (In Press.)
TWIGT, J.M., HAMMICHE, F., SINCLAIR, K.D., BECKERS, N.G., VISSER, J.A., LINDEMANS, J., DE JONG, F.H., LAVEN, J.S.E. and STEEGERS-THEUNISSEN, R.P., 2011. Preconception folic acid use modulates estradiol and follicular responses to ovarian stimulation. JCEM: The Journal of Clinical Endocrinology and Metabolism. 96(2), E322-329 HUGHES, J., KWONG, W.Y., LI, D., SALTER, A.M., LEA, R.G. and SINCLAIR, K.D., 2011. Effects of omega-3 and -6 polyunsaturated fatty acids on ovine follicular cell steroidogenesis, embryo development and molecular markers of fatty acid metabolism Reproduction: The Journal of the Society for Reproduction and Fertility. 141(1), 105-118 MALONEY, CA, HAY, SM, YOUNG, LE, SINCLAIR, KD and REES, WD, 2011. A Methyl-Deficient Diet Fed To Rat Dams During The Peri-Conception Period Programs Glucose Homeostasis In Adult Male But Not Female Offspring Journal Of Nutrition. 141(1), 95-100 WONNACOTT, K.E., KWONG, W.Y., HUGHES, J., SALTER, A.M., LEA, R.G., GARNSWORTHY, P.C. and SINCLAIR, K.D., 2010. Dietary omega-3 and-6 polyunsaturated fatty acids affect the composition and development of sheep granulosa cells, oocytes and embryos Reproduction. 139(1), 57-69 RHIND SM, EVANS NP, BELLINGHAM M, SHARPE RM, COTINOT C, MANDON-PEPIN B, LOUP B, SINCLAIR KD, LEA RG, POCAR P, FISCHER B, VAN DER ZALM E, HART K, SCHMIDT J, AMEZAGA MR and FOWLER PA, 2010. Effects Of Environmental Pollutants On The Reproduction And Welfare Of Ruminants. Animal : An International Journal Of Animal Bioscience. 4(7), 1227-1239 KWONG, W.Y., ADAMIAK, S.J., GWYNN, A., SINGH, R. and SINCLAIR, K.D., 2010. Endogenous folates and single-carbon metabolism in the ovarian follicle, oocyte and pre-implantation embryo Reproduction: The Journal of the Society for Reproduction and Fertility. 139(4), 705-15 SINCLAIR KD, KARAMITRI A and GARDNER DS, 2010. Dietary Regulation Of Developmental Programming In Ruminants: Epigenetic Modifications In The Germline. Society Of Reproduction And Fertility Supplement. 67, 59-72
GARDNER, D S, OZANNE, S E and SINCLAIR, K D, 2009. Effect of the early-life nutritional environment on fecundity and fertility of mammals. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 364(1534), 3419-27 GARNSWORTHY, P.C., FOULADI-NASHTA, A.A., MANN, G.E., SINCLAIR, K.D. and WEBB, R., 2009. Effect of dietary-induced changes in plasma insulin concentrations during the early post partum period on pregnancy rate in dairy cows Reproduction. 137(4), 759-768 FOULADI-NASHTA AA, WONNACOTT KE, GUTIERREZ CG, GONG JG, SINCLAIR KD, GARNSWORTHY PC and WEBB R, 2009. Oocyte Quality In Lactating Dairy Cows Fed On High Levels Of N-3 And N-6 Fatty Acids. Reproduction (Cambridge, England). 138(5), 771-81 ROOKE JA, AINSLIE A, WATT RG, ALINK FM, MCEVOY TG, SINCLAIR KD, GARNSWORTHY PC and WEBB R, 2009. Dietary Carbohydrates And Amino Acids Influence Oocyte Quality In Dairy Heifers. Reproduction, Fertility, And Development. 21(3), 419-27 KANAKKAPARAMBIL, R., SINGH, R., LI, D., WEBB, R. and SINCLAIR, K.D., 2009. B-vitamin and homocysteine status determines ovarian response to Gonadotropin treatment in sheep. Biology of Reproduction. 80(4), 743-752 WONNACOTT KE, KWONG WY, HUGHES J, SALTER AM, LEA RG, GARNSWORTHY PC and SINCLAIR KD, 2009. Dietary omega-3 and -6 polyunsaturated fatty acids affect the composition and development of sheep granulosa cells, oocytes and embryos. Reproduction (Cambridge, England). 139(1), 57-69 THURSTON, A., TAYLOR, J., GARDNER, J., SINCLAIR, K.D. and YOUNG, L.E., 2008. Monoallelic expression of nine imprinted genes in the sheep embryo occurs after the blastocyst stage Reproduction. 135(1), 29-40 GARNSWORTHY, P.C., LOCK, A., MANN, G.E., SINCLAIR, K.D. and WEBB, R, 2008. Nutrition, metabolism, and fertility in dairy cows: 1. Dietary energy source and ovarian function Journal of Dairy Science. 91(10), 3814-3823 GARNSWORTHY, P.C., LOCK, A., MANN, G.E., SINCLAIR, K.D. and WEBB, R, 2008. Nutrition, metabolism, and fertility in dairy cows: 2. Dietary fatty acids and ovarian function Journal of Dairy Science. 91(10), 3824-3833 ROOKE, JA, AINSLIE, A, WATT, RG, ALINK, FM, MCEVOY, TG, SINCLAIR, KD, GARNSWORTHY, PC and WEBB, R, 2008. Feeding Frequency Has Diet-Dependent Effects On Plasma Hormone Concentrations But Does Not Affect Oocyte Quality In Dairy Heifers Fed Fibre- Or Starch-Based Diets Animal. 2(9), 1361-1370 GARNSWORTHY PC, GONG JG, ARMSTRONG DG, NEWBOLD JR, MARSDEN M, RICHARDS SE, MANN GE, SINCLAIR KD and WEBB R, 2008. Nutrition, Metabolism, And Fertility In Dairy Cows: 3. Amino Acids And Ovarian Function. Journal Of Dairy Science. 91(11), 4190-7 SINCLAIR, K.D., LUNN, L.A., KWONG, W.Y., WONNACOTT, K., LINFORTH, R.S.T. and CRAIGON, J., 2008. Amino acid and fatty acid composition of follicular fluid as predictors of in-vitro embryo development Reproductive Biomedicine Online. 16(6), 859-868 GARNSWORTHY, P.C., SINCLAIR, K.D. and WEBB, R., 2008. Integration of physiological mechanisms that influence fertility in dairy cows Animal. 2(8), 1144-1152 SINCLAIR KD, LUNN LA, KWONG WY, WONNACOTT K, LINFORTH RST and CRAIGON J, 2008. Amino acid and fatty acid composition of follicular fluid as predictors of in-vitro embryo development. Reproductive biomedicine online. 16(6), 859-68
GARNSWORTHY PC, LOCK A, MANN GE, SINCLAIR KD and WEBB R, 2008. Nutrition, metabolism, and fertility in dairy cows: 2. Dietary fatty acids and ovarian function. Journal of dairy science. 91(10), 3824-33 GARNSWORTHY PC, LOCK A, MANN GE, SINCLAIR KD and WEBB R, 2008. Nutrition, metabolism, and fertility in dairy cows: 1. Dietary energy source and ovarian function. Journal of dairy science. 91(10), 3814-23 ROOKE JA, AINSLIE A, WATT RG, ALINK FM, MCEVOY TG, SINCLAIR KD, GARNSWORTHY PC and WEBB R, 2008. Feeding frequency has diet-dependent effects on plasma hormone concentrations but does not affect oocyte quality in dairy heifers fed fibre- or starch-based diets. Animal : an international journal of animal bioscience. 2(9), 1361-70 GARNSWORTHY PC, SINCLAIR KD and WEBB R, 2008. Integration of physiological mechanisms that influence fertility in dairy cows. Animal : an international journal of animal bioscience. 2(8), 1144-52 GARDNER DS, LEA RG and SINCLAIR KD, 2008. Developmental programming of reproduction and fertility: what is the evidence? Animal : an international journal of animal bioscience. 2(8), 1128-34 SINCLAIR, KEVIN D, ALLEGRUCCI, CINZIA, SINGH, RAVINDER, GARDNER, DAVID S, SEBASTIAN, SONIA, BISPHAM, JAYSON, THURSTON, ALEXANDRA, HUNTLEY, JOHN F, REES, WILLIAM D, MALONEY, CHRISTOPHER A and LEA, RICHARD, 2007. DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proceedings of the National Academy of Sciences of the United States of America. 104(49), 19351-6
ROOKE, JA, MCEVOY, TG, ASHWORTH,CJ, ROBINSON,JJ, WILMUT,I, YOUNG,LE and SINCLAIR,KD, 2007. Ovine fetal development is more sensitive to perturbation by the presence of serum in embryo culture before rather than after compaction. Theriogenology. 67(3), 639-647 SINCLAIR,K.D, LEA,R.G, REES,W.D and YOUNG,L.E, 2007. The developmental origins of health and disease; current theories and epigenetic mechanisms Society for Reproduction and Fertility Supplement. 64, 425-443
SINGH, R and SINCLAIR, K D, 2007. Metabolomics: approaches to assessing oocyte and embryo quality. Theriogenology. 68 Suppl 1, S56-62 SINCLAIR, K D, LEA, R G, REES, W D and YOUNG, L E, 2007. The developmental origins of health and disease: current theories and epigenetic mechanisms. Society of Reproduction and Fertility supplement. 64, 425-43
SINGH, R, FOULADI-NASHTA, A A, LI, D, HALLIDAY, N, BARRETT, D A and SINCLAIR, K D, 2006. Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation. Journal of cellular biochemistry. 99(1), 146-55 POWELL, K, ROOKE, J A, MCEVOY, T G, ASHWORTH, C J, ROBINSON, J J, WILMUT, I, YOUNG, L E and SINCLAIR, K D, 2006. Zygote donor nitrogen metabolism and in vitro embryo culture perturbs in utero development and IGF2R expression in ovine fetal tissues. Theriogenology. 66(8), 1901-12 ADAMIAK, S.J., POWELL, K., ROOKE, J.A., WEBB, R. and SINCLAIR, K.D., 2006. Body composition, dietary carbohydrates and fatty acids determine post-fertilisation development of bovine oocytes in vitro. Reproduction. 131(2), 247-58 STEELE, W, ALLEGRUCCI, C, SINGH, R, LUCAS, E, PRIDDLE, H, DENNING, C, SINCLAIR, K and YOUNG, L, 2005. Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction? Reproductive Biomedicine online. 10(6), 755-66 ALLEGRUCCI, C., DENNING, C.N., BURRIDGE, P., STEELE, W., SINCLAIR, K.D. and YOUNG, L.E., 2005. Human embryonic stem cells as a model for nutritional programming: an evaluation Reproductive Toxicology. 20(3), 353-367 ADAMIAK, S.J., MACKIE, K., WATT, R.G., WEBB, R. and SINCLAIR, K.D., 2005. Impact of nutrition on oocyte quality: cumulative effects of body composition and diet leading to hyperinsulinemia in cattle. Biology of Reproduction. 73(5), 918-926 ALLEGRUCCI C, DENNING CN, BURRIDGE P, STEELE W, SINCLAIR KD and YOUNG LE, 2005. Human embryonic stem cells as a model for nutritional programming: an evaluation. Reproductive toxicology (Elmsford, N.Y.). 20(3), 353-67 YOUNG,L.E., REES,W.D. and SINCLAIR,K.D, 2004. Programming in the pre-implantation embryo. In: Fetal nutrition and Adult Disease: Programming of chronic disease through fetal exposure to undernutrition CAB International, Oxford.
QUINTANS, G., VINOLES, C. and SINCLAIR, K. D., 2004. Follicular growth and ovulation in postpartum beef cows following calf removal and GnRH treatment Animal Reproduction Science. VOL 80(NUMBER 1-2), 5-14 ROOKE, J A, EWEN, M, MACKIE, K, STAINES, M E, MCEVOY, T G and SINCLAIR, K D, 2004. Effect of ammonium chloride on the growth and metabolism of bovine ovarian granulosa cells and the development of ovine oocytes matured in the presence of bovine granulosa cells previously exposed to ammonium chloride. Animal Reproduction Science. 84(1-2), 53-71 QUINTANS, G, VIÑOLES, C and SINCLAIR, K D, 2004. Follicular growth and ovulation in postpartum beef cows following calf removal and GnRH treatment. Animal Reproduction Science. 80(1-2), 5-14
MANN, G.E., GREEN, M.P., SINCLAIR, K.D., DEMMERS, K.J., FRAY, M.D., GUTIERREZ, C.G., GARNSWORTHY, P.C. and WEBB, R., 2003. Effects of circulating progesterone and insulin on early embryo development in beef heifers Animal Reproduction Science. VOL 79(NUMBER 1-2), 71-79 SINCLAIR, K.D., GARNSWORTHY, P.C. and WEBB, R., 2003. Recent advances in reproductive technologies : implications for livestock production and animal nutrition. In: GARNSWORTHY, P.C. and WISEMAN, J., eds., Recent Advances in Animal Nutrition - 2003 Nottingham University Press. 89-113
MCEVOY, T. G., ASHWORTH, C. J., ROOKE, J. A. and SINCLAIR, K. D., 2003. Consequences of manipulating gametes and embryos of ruminant species Reproduction. Supplement. ISSU 61, 167-182
SINCLAIR, K. D., ROOKE, J. A. and MCEVOY, T. G., 2003. Regulation of nutrient uptake and metabolism in pre-elongation ruminant embryos Reproduction. Supplement. ISSU 61, 371-385
SINCLAIR KD, ROOKE JA and MCEVOY TG, 2003. Regulation of nutrient uptake and metabolism in pre-elongation ruminant embryos. Reproduction (Cambridge, England) Supplement. 61, 371-85
MCEVOY TG, ASHWORTH CJ, ROOKE JA and SINCLAIR KD, 2003. Consequences of manipulating gametes and embryos of ruminant species. Reproduction (Cambridge, England) Supplement. 61, 167-82
MANN GE, GREEN MP, SINCLAIR KD, DEMMERS KJ, FRAY MD, GUTIERREZ CG, GARNSWORTHY PC and WEBB R, 2003. Effects of circulating progesterone and insulin on early embryo development in beef heifers. Animal reproduction science. 79(1-2), 71-9 PUSHPAKUMARA, P.G.A., ROBINSON, R.S., DEMMERS, K.J., MANN, G.E., SINCLAIR, K.D., WEBB, R. and WATHES, D.C., 2002. Expression of the insulin-like growth factor (IGF) system in the bovine oviduct at oestrus and during early pregnancy Reproduction. VOL 123(PART 6), 859-868 DAWUDA, P. M., SCAIFE, J. R., HUTCHINSON, J. S. and SINCLAIR, K. D., 2002. Mechanisms linking under-nutrition and ovarian function in beef heifers Animal Reproduction Science. VOL 74(NUMBER 1-2), 11-26 SINCLAIR, K. D., MOLLE, G., REVILLA, R., ROCHE, J. F., QUINTANS, G., MARONGIU, L., SANZ, A., MACKEY, D. R. and DISKIN, M. G., 2002. Ovulation of the first dominant follicle arising after day 21 post partum in suckling beef cows Animal Science. VOL 75(PART 1), 115-126
DAWUDA PM, SCAIFE JR, HUTCHINSON JS and SINCLAIR KD, 2002. Mechanisms linking under-nutrition and ovarian function in beef heifers. Animal reproduction science. 74(1-2), 11-26 PUSHPAKUMARA PG, ROBINSON RS, DEMMERS KJ, MANN GE, SINCLAIR KD, WEBB R and WATHES DC, 2002. Expression of the insulin-like growth factor (IGF) system in the bovine oviduct at oestrus and during early pregnancy. Reproduction (Cambridge, England). 123(6), 859-68
ARMSTRONG, D.G., MCEVOY, T.G., BAXTER, G., ROBINSON, J.J., HOGG, C.O., WOAD, K.J., WEBB, R. and SINCLAIR, K.D., 2001. Effect of dietary energy and protein on bovine follicular dynamics and embryo production in vitro : associations with the ovarian insulin-like growth factor system Biology of Reproduction. 64(6), 1624-1632 YOUNG, L.E., FERNANDES, K., MCEVOY, T.G., BUTTERWITH, S.C., GUTIERREZ, C.G., CAROLAN, C., BROADBENT, P.J., ROBINSON, J.J., WILMUT, I. and SINCLAIR, K.D., 2001. Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture Nature Genetics. 27(2), 153-154 ARMSTRONG, D G, MCEVOY, T G, BAXTER, G, ROBINSON, J J, HOGG, C O, WOAD, K J, WEBB, R and SINCLAIR, K D, 2001. Effect of dietary energy and protein on bovine follicular dynamics and embryo production in vitro: associations with the ovarian insulin-like growth factor system. Biology of Reproduction. 64(6), 1624-32 MALTIN, C A, DELDAY, M I, SINCLAIR, K D, STEVEN, J and SNEDDON, A A, 2001. Impact of manipulations of myogenesis in utero on the performance of adult skeletal muscle. Reproduction. 122(3), 359-74 MCEVOY, T., ROBINSON, J. J., ASHWORTH, C. J., ROOKE, J. A. and SINCLAIR, K. D., 2001. FEED AND FORAGE TOXICANTS AFFECTING EMBRYO SURVIVAL AND FETAL DEVELOPMENT Theriogenology. VOL 55(NO 1), 113-130 SINCLAIR, K. D., LOBLEY, G. E., HORGAN, G. W., KYLE, D. J., PORTER, A. D., MATTHEWS, K. R., WARKUP, C. C. and MALTIN, C. A., 2001. Factors influencing beef eating quality. 1. Effects of nutritional regimen and genotype on organoleptic properties and instrumental texture Animal Science. VOL 72(PART 2), 269-278
MALTIN,C.A., LOBLEY,G.E., GRANT,G.M., MILLER,L.A., KYLE,D.G., HORGAN,G.W., MATTHEWS,K.R. and SINCLAIR,K.D., 2001. Factors influencing beef eating quality. II. Effect of nutritional regimen and genotype on muscle fibre characteristics Animal Science. 72, 279
SINCLAIR KD, YOUNG LE, WILMUT I and MCEVOY TG, 2001. In-utero overgrowth in ruminants following embryo culture: lessons from mice and a warning to men. Human reproduction (Oxford, England). 15 Suppl 5, 68-86
MCEVOY TG, ROBINSON JJ, ASHWORTH CJ, ROOKE JA and SINCLAIR KD, 2001. Feed and forage toxicants affecting embryo survival and fetal development. Theriogenology. 55(1), 113-29 YOUNG LE, FERNANDES K, MCEVOY TG, BUTTERWITH SC, GUTIERREZ CG, CAROLAN C, BROADBENT PJ, ROBINSON JJ, WILMUT I and SINCLAIR KD, 2001. Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture. Nature genetics. 27(2), 153-4 SINCLAIR, K.D., KURAN, M., GEBBIE, F.E., WEBB, R. and MCEVOY, T.G., 2000. Nitrogen metabolism and fertility in cattle: II. Development of oocytes recovered from heifers offered diets differing in their rate of nitrogen release in the rumen Journal of Animal Science. VOL 78(PART 10), 2670-2680
MCEVOY, T. G., SINCLAIR, K. D., YOUNG, L. E., WILMUT, I. and ROBINSON, J. J., 2000. Large offspring syndrome and other consequences of ruminant embryo culture in vitro: relevance to blastocyst culture in human ART Human Fertility. VOL 3(PART 4), 238-246
SINCLAIR, K. D., YOUNG, L. E., WILMUT, I. and MCEVOY, T. G., 2000. In-utero overgrowth in ruminants following embryo culture: lessons from mice and a warning to men Human Reproduction. VOL 15(SUPP/5), 68-86
MCEVOY,, SINCLAIR,, YOUNG,, WILMUT, and ROBINSON,, 2000. Large offspring syndrome and other consequences of ruminant embryo culture in vitro: relevance to blastocyst culture in human ART. Human Fertility. 3(4), 238-246
SINCLAIR, K D, SINCLAIR, L A and ROBINSON, J J, 2000. Nitrogen metabolism and fertility in cattle: I. Adaptive changes in intake and metabolism to diets differing in their rate of energy and nitrogen release in the rumen. Journal of Animal Science. 78(10), 2659-69
SINCLAIR KD, KURAN M, GEBBIE FE, WEBB R and MCEVOY TG, 2000. Nitrogen metabolism and fertility in cattle: II. Development of oocytes recovered from heifers offered diets differing in their rate of nitrogen release in the rumen. Journal of animal science. 78(10), 2670-80
LOBLEY GE, SINCLAIR KD, GRANT CM, MILLER L, MANTLE D, CALDER AG, WARKUP CC and MALTIN CA, 2000. The effects of breed and level of nutrition on whole-body and muscle protein metabolism in pure-bred Aberdeen angus and Charolais beef steers. The British journal of nutrition. 84(3), 275-84
MCEVOY TG, SINCLAIR KD, BROADBENT PJ, GOODHAND KL and ROBINSON JJ, 1999. Post-natal growth and development of Simmental calves derived from in vivo or in vitro embryos. Reproduction, fertility, and development. 10(6), 459-64 SINCLAIR KD, MCEVOY TG, MAXFIELD EK, MALTIN CA, YOUNG LE, WILMUT I, BROADBENT PJ and ROBINSON JJ, 1999. Aberrant fetal growth and development after in vitro culture of sheep zygotes. Journal of reproduction and fertility. 116(1), 177-86
ARMSTRONG, D.G., BAXTER, G., HOGG, C.O. and WOAD, K.J., 1998. The effect of different energy and protein diets on the expression of mRNA encoding components of the ovarian IGF-system in cattle Journal of Reproduction and Fertility. Abstract Series. ISSUE 22, 13
SINCLAIR, K D, DUNNE, L D, MAXFIELD, E K, MALTIN, C A, YOUNG, L E, WILMUT, I, ROBINSON, J J and BROADBENT, P J, 1998. Fetal growth and development following temporary exposure of day 3 ovine embryos to an advanced uterine environment. Reproduction, Fertility and Development. 10(3), 263-9 YOUNG LE, SINCLAIR KD and WILMUT I, 1998. Large offspring syndrome in cattle and sheep. Reviews of reproduction. 3(3), 155-63 MAXFIELD EK, SINCLAIR KD, DUNNE LD, BROADBENT PJ, ROBINSON JJ, STEWART E, KYLE DG and MALTIN CA, 1998. Temporary exposure of ovine embryos to an advanced uterine environment does not affect fetal weight but alters fetal muscle development. Biology of reproduction. 59(2), 321-5 MAXFIELD EK, SINCLAIR KD, BROADBENT PJ, MCEVOY TG, ROBINSON JJ and MALTIN CA, 1998. Short-term culture of ovine embryos modifies fetal myogenesis. The American journal of physiology. 274(6 Pt 1), E1121-3
ARMSTRONG, D.G., BAXTER, G., GUTIERREZ, C.G., WOAD, K.J., SINCLAIR, K.D., ROBINSON, J.J., MCEVOY, T.G. and WEBB, R., 1997. Ovarian IGF-II mRNA expression in cattle fed different energy and protein diets Journal of Reproduction and Fertility. Abstract Series. 19, 51
MCEVOY, T.G., SINCLAIR, K.D., STAINES, M.E., ROBINSON, J.J., ARMSTRONG, D. and WEBB, R., 1997. In vitro blastocyst production in relation to energy and protein intake prior to oocyte collection Journal of Reproduction and Fertility. Abstract Series. 19, 51