Mark Pope

Contact

• workRoom B13 North Lab
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 9516547
• mark.pope@nottingham.ac.uk

Biography

I joined the university as a Senior Research Technician in the Genetics department in 2004 working on a BHF funded project looking for unique variations in the sequence of candidate genes within a Cohort of patients with atrial septal defects.

I next joined Academic Child Health in Jan 2008, where I was involved in early life research with particular emphasis on brown adipose tissue development. I also provided laboratory training and support for clinicians and Ph.D. students in the department.

In January 2022 I moved to the School of Biosciences as a Technical Specialist in Cell Culture within the Division of Nutrition and Dietetics, based in North Lab, Sutton Bonington Campus.

Expertise Summary

Primary stem cell 2D and 3D culture, PCR, qPCR, primer design, Western blotting, histology, Immunohistochemistry, dHPLC

Research Summary

The development of adipose in early life.

Recent Publications

• SYMONDS, M E, ALDISS, PETER, DELLSCHAFT, NEELE, LAW, JAMES, FAINBERG, HERNAN, POPE, MARK, SACKS, HAROLD and BUDGE, HELEN, 2018. Brown adipose tissue development and function and its impact on reproduction. The Journal of endocrinology.
• FAINBERG, HERNAN P., BIRTWISTLE, MARK, ALAGAL, REHAM, ALHADDAD, AHMAD, POPE, MARK, DAVIES, GRAEME, WOODS, RACHEL, CASTELLANOS, MARCOS, MAY, SEAN T., ORTORI, CATHARINE A., BARRETT, DAVID A., PERRY, VIV, WIENS, FRANK, STAHL, BERND, VAN DER BEEK, ELINE, SACKS, HAROLD, BUDGE, HELEN and SYMONDS, MICHAEL E., 2018. Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation SCIENTIFIC REPORTS. 8((1)), 9328
• SYMONDS ME, FARHAT G, ALDISS P, POPE M and BUDGE H, 2018. Brown adipose tissue and glucose homeostasis - the link between climate change and the global rise in obesity and diabetes. Adipocyte. (In Press.)
• SYMONDS ME, ALDISS P, POPE M and BUDGE H, 2018. Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy. F1000Research. 7,

• View all publications

Past Research

Detection of novel single nucleotide polymorphisms and other genetic anomalies in DNA samples from congenital heart defect patients.

Future Research

Mechanisms of physiological adaptation in early life.

• SYMONDS, M E, ALDISS, PETER, DELLSCHAFT, NEELE, LAW, JAMES, FAINBERG, HERNAN, POPE, MARK, SACKS, HAROLD and BUDGE, HELEN, 2018. Brown adipose tissue development and function and its impact on reproduction. The Journal of endocrinology.
• FAINBERG, HERNAN P., BIRTWISTLE, MARK, ALAGAL, REHAM, ALHADDAD, AHMAD, POPE, MARK, DAVIES, GRAEME, WOODS, RACHEL, CASTELLANOS, MARCOS, MAY, SEAN T., ORTORI, CATHARINE A., BARRETT, DAVID A., PERRY, VIV, WIENS, FRANK, STAHL, BERND, VAN DER BEEK, ELINE, SACKS, HAROLD, BUDGE, HELEN and SYMONDS, MICHAEL E., 2018. Transcriptional analysis of adipose tissue during development reveals depot-specific responsiveness to maternal dietary supplementation SCIENTIFIC REPORTS. 8((1)), 9328
• SYMONDS ME, FARHAT G, ALDISS P, POPE M and BUDGE H, 2018. Brown adipose tissue and glucose homeostasis - the link between climate change and the global rise in obesity and diabetes. Adipocyte. (In Press.)
• SYMONDS ME, ALDISS P, POPE M and BUDGE H, 2018. Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy. F1000Research. 7,
• HENRY, B.A., POPE, M., BIRTWISTLE, M., LOUGHNAN, R., ALAGAL, R., FULLER-JACKSON, J.-P., PERRY, V., BUDGE, H., CLARKE, I.J. and SYMONDS, M.E., 2017. Ontogeny and thermogenic role for sternal fat in female sheep Endocrinology. 158(7), 2212-2225
• ALDISS P, BETTS J, SALE C, POPE M, BUDGE H and SYMONDS ME, 2017. Exercise-induced 'browning' of adipose tissues. Metabolism: clinical and experimental. 81, 63-70
• SYMONDS, M.E., DELLSCHAFT, N., POPE, M., BIRTWISTLE, M., ALAGAL, R., KEISLER, D. and BUDGE, H., 2016. Developmental programming, adiposity, and reproduction in ruminants Theriogenology.
• SYMONDS, M.E., POPE, M. and BUDGE, H., 2015. The Ontogeny of Brown Adipose Tissue Annual Review of Nutrition. 35(1), 295-320
• FAINBERG HP, SHARKEY D, SEBERT S, WILSON V, POPE M, BUDGE H and SYMONDS ME, 2013. Suboptimal maternal nutrition during early fetal kidney development specifically promotes renal lipid accumulation following juvenile obesity in the offspring. Reproduction, fertility, and development. 25(5), 728-36
• POPE M, BUDGE H and SYMONDS ME, 2013. The developmental transition of ovine adipose tissue through early life. Acta physiologica (Oxford, England). (In Press.)
• SYMONDS, M.E., POPE, M., SHARKEY, D. and BUDGE, H., 2012. Adipose tissue and fetal programming Diabetologia. 55(6), 1597-1606
• MICHAEL E SYMONDS, MARK POPE and HELEN BUDGE, 2012. Session 1: Early nutrition programming, life performance and cognitive function Adipose tissue development during early life: novel insights into energy balance from small and large mammals: Metabolic flexibility in animal and human nutrition In: Oskar Kellner Symposium 2011. 1-7
• SYMONDS ME, POPE M and BUDGE H, 2012. Adipose tissue development during early life: novel insights into energy balance from small and large mammals. The Proceedings of the Nutrition Society. 71(3), 363-70
• RIVERON, JTG, GHOSH, TK, POPE, M, EASON, J, BULOCK, F, THOMBOROUGH, C, KIRK, EP, FATKIN, D, FENELEY, MP, HARVEY, RP, ARMOUR, JAL and BROOK, JD, 2010. alpha,-cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects In: British Human Genetics Conference. S76-S76
• MATSSON, H, EASON, J, BOOKWALTER, C S, KLAR, J, GUSTAVSSON, P, SUNNEGÅRDH, J, ENELL, H, JONZON, A, VIKKULA, M, GUTIERREZ, I, GRANADOS-RIVERON, J, POPE M, BU’LOCK F, COX J: ROBINSON T E, SONG F, BROOK J D, MARSTON S and TRYBUS K M AND DAHL N, 2008. Alpha-cardiac actin mutations produce atrial septal defects. Human Molecular Genetics. 17(2), 256-65
• GRANADOS-RIVERON JT, POPE M, BU'LOCK FA, THORNBOROUGH C, EASON J, SETCHFIELD K, KETLEY A, KIRK EP, FATKIN D, FENELEY MP, HARVEY RP and BROOK JD, 1. Combined mutation screening of NKX2-5, GATA4, and TBX5 in congenital heart disease: multiple heterozygosity and novel mutations. Congenital heart disease. 7(2), 151-9
• BREEN M, LANGFORD CF, CARTER NP, HOLMES NG, DICKENS HF, THOMAS R, SUTER N, RYDER EJ, POPE M and BINNS MM, 1. Fish Mapping And Identification Of Canine Chromosomes. The Journal Of Heredity. 90(1), 27-30