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Peter Aldiss

Nottingham Research Fellow, Faculty of Medicine & Health Sciences

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Biography

Dr. Peter Aldiss is a Junior Group Leader and Nottingham Research Fellow working across the GI and Liver Theme and Nottingham Digestive Disorders Centre of NIHR Nottingham Biomedical Research Centre and the Biodiscovery Institute. He was awarded his PhD in adipose tissue biology from the University of Nottingham in 2020 having moved to the University of Birmingham in 2018 as a Research Fellow to work with Prof. Gareth Lavery on the role of NAD+ precursors to regulate skeletal muscle metabolism. In 2020, he was awarded a Danish Diabetes Academy Fellowship to work under Prof. Matt Gilum at the Novo Nordisk Centre for Basic Metabolic Research at the University of Copenhagen to investigate the genetic, and peripheral regulation of alcohol and sugar intake. In 2023 he returned to Nottingham following the award of an independent Nottingham Research Fellowship to start his own group.

Expertise Summary

Research Summary

Pete's research is aimed at understanding biological signals that influence what we eat and drink, with a focus on the drive to consume rewarding foods such as sugar and alcohol. His ongoing research… read more

Current Research

Pete's research is aimed at understanding biological signals that influence what we eat and drink, with a focus on the drive to consume rewarding foods such as sugar and alcohol. His ongoing research will seek to understand how genetic variation in digestive enzymes influences preference for sucrose rich foods (link) and whether we can target these pathways pharmacologically to reduce population wide sugar intake. Further, he is interested in understanding how peripheral signals from metabolically active tissues (gut, liver, adipose and muscle) interact to regulate our preferences for alcohol and other palatable, or rewarding, nutrients/substances with a focus on sugar and alcohol intake.

To achieve this, his programme of research combines pre-clinical animal models to investigate the impact of genetics or peripheral factors on appetite and feeding, including preference and binging with human pharmacology and recruit-by-genotype studies to investigate food liking, ad-lib buffet paradigms and neuroimaging.

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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